Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ELF1 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10207087 14970218
ELF1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15337760 15645134
CREBBP H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
PRMT5 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1209814109 23071334
H4C6 BRD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20709061 7989531
H4C6 PRMT6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18079182 11448779
H4C6 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18079182 11448779
H4C6 PRMT5 â—¼   METHYLATION ✅ 2.0 0.8 intact 1209814109 23071334
HDAC1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10220385
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EP300 H3C14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11509556
CREBBP H3C14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11509556
JUN AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 11192249
RUNX3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24042352 22231444
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
AKT1 SP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21619873 21777568
SMAD4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD4 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12099698 15242331
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
KMT2A BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056311 19208841
CHGB CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NFATC2 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17377532 16873067
YAP1 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18701449 18280240
EP300 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24229708 15138260
CHRM5 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CBFB PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18316480 26010396
PPM1D CBFB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 22544321 22065775
CDK1 CBFB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17171635 16407259
CCNB1 CBFB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17171635 16407259
CBFB HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
CCNB1 RUNX2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17171635 16407259
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
CDK1 RUNX2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17171635 16407259
MAPK1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17205132
NFATC2 CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12453415
LRRK2 CHGB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
SMAD4 COL7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9582342 9843964
COPRS PRMT5 â—¼   COLOCALIZATION 2.0 0.8 intact 6543161 18404153
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
MAPK1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8941362
SMAD4 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9679056 9679060
CREBBP SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9679056 9679060
RNF7 CUL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
EP300 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
HIPK2 EP300 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16917507 5218981
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
FLI1 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21536859
ERG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25277175 20820186
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
ESR1 JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11477071
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
PRMT6 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20047962
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
PRMT5 FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOS MAPK3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
FOS MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
FOS SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11854297
FOS HSPH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20188076
FOS NFATC2 â—¼   PROXIMITY 2.0 0.8 intact 18172215 0705181105
KMT2A FOXC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16199523
NFATC2 FOXP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17377532 16873067
GATA1 RUNX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16628190
SMAD4 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
RUNX1 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
RUNX1 HIPK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16917507 5218981
HSPBP1 HSPA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
JUN RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11604227
JUN PPM1D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20093361
KMT2A RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23817177 22012064
MYOD1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10805738 9988769
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
NFATC2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23858296 22333584
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
SMAD4 MYOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
MYOD1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17194702 17043109
RUNX1 NFATC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17377532 16873067
RUNX2 PPM1D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1107017108 22065775
PPM1D RUNX2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 22544321 22065775
RUNX2 PPM1D â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 1107017108 22065775
RUNX1 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18316480 26010396
SMAD1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19664780 24692107
SMAD1 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17215250 22298955
YAP1 RUNX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10228168 26364597
SMAD4 RUNX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16135801 10531362
SMARCA2 SMARCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10078207 16713569
SMARCA4 TCEB2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SMARCA4 SMARCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10078207 16713569
SMARCC1 SMARCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1459453 19785031
CCND1 CDK1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
JUNB EP300 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21937452 15308641 17510411
EP300 PAX5 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21357426 31941781
EP300 ATF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24069158 10327051
CBFB ERG â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
CBFB FLI1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
MYC CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC CEBPZ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
ERG EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 28536097
FOS ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
JUN HDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 17056544
MYC JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
MYC RUNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
SMARCA4 TCEB1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
TCEB1 TCEB2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RUNX1 CBFB â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 17431401 5219852
GATA1 DHX36 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 35140242 26186194
ERG RUNX2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
ESR1 JUNB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 11477071
FLI1 RUNX2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
SMAD4 JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649 10220381
BTF3 RPL35 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RUNX1 CDK6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17431401 25241761
ESR1 HDAC4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16051668 19893013
HDAC4 RUNX3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24229708 15138260
RUNX1 EP300 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16917507 14752096
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
SIN3A IKZF1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12015313 10357820 11959865
KMT2A MYB â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RUNX2 SMAD1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
HDAC1 RUNX1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
SMAD4 EP300 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18215124 25514493 10887155 22033265 9679056 14612423 9843571
EP300 RUNX3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24229708 15138260
ATF2 JUNB â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
CCND1 ESR1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
EP300 RUNX2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
JUN MAPK1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
MYC CDK6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22094256 28205554 28628118
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMARCA2 SMARCA4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
EP300 CCND1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10567390 15951563 11788592
MYOD1 CDK4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10601020 10022835
CDK4 CDK6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 28205554 28628118
ELF2 RUNX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14970218 10207087
FOS RUNX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11274169 11641401
IKZF1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 30760870 10204490 10357820 12015313 23752268 16189514
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
JUN RUNX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11274169 11641401
SMAD4 JUNB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10220381 16189514 15231748
CBFB RUNX3 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ESR1 HSPA4 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 MYOD1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CREBBP JUN â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
JUNB ATF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 16511568 20102225
MYC CDK4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22094256 28205554 21988832 28628118
EP300 HIPK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16917507 29170424
JUN ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17317669 16713569 23747343 11477071
RUNX2 FOS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11274169 11641401
FOS NFATC2 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
RUNX2 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11274169 11641401
JUN MYOD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 1310896 16713569 8380166
ATF2 FOS â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
FOS JUNB â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
MYOD1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10973962 16901893 21689744
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
AKT1 SMARCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16568092
MYC APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
FOS ATF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 1828107 32296183 25416956 16511568 23661758 25609649 20102225 26186194 20195357 1827203
HDAC1 CBFB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
CBFB SIN3A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
CBFB PRMT6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
MYB CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17242210
NFATC2 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12453415 11402342 11030334
FOS CHGB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20359597
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20851880 22298955 12697832
ESR1 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28539435 18657504 11029009
RUNX2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17350616
ESR1 FOXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25303530 18414489
GATA1 FLI1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10364157 12556498 12724402 16189514
NFATC2 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25126782 16517728 17463169
MAPK1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15967790
SIN3A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12724404 24981860 14593184 26496610 11102443 17827154 10220385 14647463 9885572 15695521 12398767 26344197 21258344 9804427 16331260 12091390 9150133 11602581 10640275 12920132 9790534 17643391 12943729 19182791 25314079 12374985 28514442 26949739 10444591 11931768 11171972 17956988 12453419 15451426 23752268 11784859 18059533 20585571 9520398 11118440 17962807
RUNX1 HDAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HDAC1 PRMT6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
HDAC1 RUNX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18430739 22274925 18850007
HIPK2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 12874272
IKZF1 IKZF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17383641
SMAD4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
SMAD1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 15576399 22290435 22761862
RUNX1 PRMT6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
PRMT6 SIN3A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
YAP1 RUNX1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18701449 18280240 10228168 25283809
YAP1 RUNX2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31496812 32220262 27684187 25751140 10228168
YAP1 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14765127 22153608 10228168
SMARCC1 SMARCB1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24421395
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
SMARCC1 SMARCC2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CCND1 CDK6 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
JUNB FOS â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218398 16511568
SMARCC1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
JUN NFATC2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
CBFB TCEB2 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CBFB TCEB1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
HIPK2 MYB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 15082531 16055500
JUN JUNB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 25609649 28514442 33961781
CHGB SYT1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
FOXP3 NFATC2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SMAD4 SMAD1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17183365 5219486
SMARCB1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
SMAD1 SMAD4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CDK6 CCND1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14681455 21654808 17420273 33961781 11739795 17517622 11160398 24855949 15232106 9178893 24953629 33854235 11360184 16713569 19075005 10580009 10022865
SMARCA2 SMARCC2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CBFB CUL5 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SMARCA2 SMARCC1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CREBBP MYB â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
SMAD1 YAP1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CREBBP KMT2A â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
SMARCA2 SMARCB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CUL5 RNF7 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CUL5 TCEB2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CUL5 TCEB1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
CBFB RUNX2 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
CBFB RUNX1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCA4 SMARCC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMARCA4 SMARCC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMARCA4 SMARCB1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCB1 SMARCC2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCB1 SMARCC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
TCEB1 TCEB2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCND1 CDK4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PRMT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22231400 20084102 15670829
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
PRMT6 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18077460 17898714
KMT2A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12453419 20210320 24680668 29897600 31485071 20541251 24235145 20452361
MYC H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 12695333
PRMT5 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19234465 29227283 15670829 20951943 23071334
EP300 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19423655 11689053 16332960
H4C6 BRD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14731392 20709061 12776177 17148447 19766566
AKT1 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12588998 12529330
MAPK3 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
MAPK1 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
AKT1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 27979972 25360797 26804165 28273460 25751140 24101154 25751139 34052254 25362852 28114269 28793266 26265440 31239271 25601544 28474680 33630828 26119935 27144834 27425596 25531778 34206989 34465890 21945154 25195862 31792377 18640976 28775168 32015438 32523092 22234184 33536280 33622361 30600590 24362629 34155345 24658687 21060948 33162394 20153295 26668327 21730131 26549256 21666719 25605730 26039999 34226698 20823509 34516278 27033705 32064037 32271880 32513743 33990468 24812269 32053631 32929029 34058200 25772246 26364602 27765911 26678338 27979971 33552953 28171658 34129887 21376238 28416665 25998128 25109332 12535517 31988076 26933062 26598551 25373897
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
AKT1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27053161 16107690 20101202 8206977 26680303
AKT1 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17570479 16568092
JUN APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8063812 11677255 8015372
ATF2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9990041 10915780 11850817 11410592 11739785 15691880 16405968 10464245 10500157 15314161 10066798
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
MAPK1 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10777545 17081983 21098032 9430721 12110590 20068231 19690332 15304344 19413330 10878576 15192015 7737129 18669648 19647037
MAPK3 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10777545 12110590 20068231 15304344 15192015 19647037
SMAD4 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10085140
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
CBFB RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 25678665 11179217 14729951 24522927 23333304 20195544 17431401 14752096 11276260 2845103 15331439 10856244 11742995 26598521 22498736
MYC CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 11522645 11983916 19470724
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
FOS CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 19847806 22550166 15994929 21474819 23157741 15282324 11287611 20188076 9710644 14508521
ESR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11477579 12554765 12808053 17166846 22892083 21505052 18414489 9832502 23864650 22396492 22266855 11358796 23891847 22948256 11986316 15282324 15496458 22521644 14764652 15178330 23108396 11410592 15026472 17998543 17681750 18245487 20821348 16860316 11844790 19858209 12929585 15808510 18997820 15217513 16809759 10500157 16980581 17914104
JUN CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16393119 21135252 8917510 17166846 19622016 11402335 20220142 22853846 17670745 10567390 17496887 19499154 9878062 21474819 17278098 15282324 15467760 15994313 14672732 15574422 22550166 10066798 17637753 20482821 15574764 11745411 11410592 18084253 20037604 12794082 10790372 16860316 24190040 17501623 17477349 19435822 10500157 11432833
JUNB CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15706412 10790372 11402335 20200942
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
JUN CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
ESR1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8649771 11073968 16061635 9039267
CCND1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 26203195 17145710 8978686 12036906 23562856 25416956 16985050 23707388 19767775 9837900 17517622 19237565 9372967 25502805 23718855 9228064 7736585 15232106 11360184 20837141 21306487 25910212 25241761 27107012 9150368 18537972 9178893 31217276 8867812 10580009 23007395 11160398 19470470 19075005 9106657 8259215 10908655 8756624 23543736 24855949 7568034 24218572 8662825 31515488 17205132
CCND1 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19075005 17517622 9178893 11739795 24855949 15232106 16713569 11360184 10580009 11160398
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
CDK1 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 25914884 19386523 21059642 17015473 18003885 16046550
CDK1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21902831 10942602 17014844 10082583 10764802 9710583 14749395
CDK1 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16407259
MYC CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15208653 12835716 24951594 21384303 14519204 22395148 10688915 17728244 11983916 18414489
MYC CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 11602341 17093053 22094256
CDK4 RUNX3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19351720
CDK4 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21902831 10022835 10601020
MYC CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20682794 22395148 12835716
CDK6 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 18261462 20478528 25241761 17023045 16046550 17431401 17015473 21059642 15475366 22531928
CREBBP MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8654374 11073948 12196545 16055500 18585056 16799563 23980173 14761981
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
CREBBP MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10944526 16713569 11463815 9238849 2176177
CREBBP JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8028671 10327051 2138276 9659924 9786917 16713569 17296604 8545107 18443043 16055710
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
EP300 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10944526 9001254
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12419246 14500836 10673036 22298955
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
FLI1 GATA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8510925 20110178 21205096 12724402
FLI1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12556498 12724402 16189514 10364157
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
JUNB FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1380150 2116003 8934539 11698415 9813041
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
SMAD4 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9732876 10942775
MAPK1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 12134156 20506250 15547943 8248197 7816602 15084594 12697810 8226933 20068231 18452278 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 21098038 9604935 11274345
MAPK3 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 17018293 12134156 20506250 15547943 7816602 15084594 12697810 8226933 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 26725323 21098038 9604935 11274345
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
GATA1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24336126 19522008 12832487
MAPK3 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15967790
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
HDAC4 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22298955 15537544 16613856
MYC HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1534087 14519204 1562593 10446203
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
JUN MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 2167198 19723510 1313772 8120060 8264634 1310896
JUN MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1527086 8670250 12475180
RUNX2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11641401 11274169
MAPK1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 8072547 11313929 15378002 12531896 12853483 23720779 9662434 1496019 17570479 1922387 11278277 11739718 16023596 20086174 25557171 7737130 26755651 8224842 14676207 17920329 25201974 9022811 22327296 18650425 8137421 18443042 12881422 18572021 17001009 33767435 7744008 23616010 26745678 14617628 11432833 16819515 22606284 12040039
JUN SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10220381 9312063 9732876
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
MYC JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 2123531 7775604 12695333 18838534 18414489
KMT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 16510874
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12801888
MAPK1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17289590 19914168 9335504 19914161
MAPK1 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16046550 17015473
MAPK3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 27687725 19264160 29057206 25867060 19801668 25122769 21965325 25187572
MAPK3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18463697 9155018 21071413 32482868 18988627 15210690
MAPK3 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 10197981 9335504
MAPK3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 28115363 12801888
MAPK3 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 8798443 8960373
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
SMARCB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10319872 14559996 14964309 19234532
RUNX3 RUNX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17488194 15688019 19403666
YAP1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19914168 35044719 23431053 21685363
SMAD1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17183365 9436979 24412244 11779505 31467278 21454478 10531362 15231748 12167862 23331499 21071413 11700304 12874272 16189514 18988627 20957627 9111321 15761153 32296183 26555259 14701756 14534577
SMARCB1 SMARCA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 18414052 23540691 20506188 8895581 31759698
SMARCA4 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 12917342 23540691 9891079 28420882
TCEB2 TCEB1 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
TCEB2 TCEB1 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258