Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CBX6 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18927235 0805317105
CBX6 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18927235 0805317105
CBX6 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18927235 0805317105
CBX7 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18927235 0805317105
CBX7 CBX8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17332741 5219708
CBX7 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18927235 0805317105
CBX7 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18927235 0805317105
H3-3B H2AC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H2AC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC4 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H2AC4 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H2AC4 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H3-3B H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20211137 20651253
H3C14 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H3-4 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CBX5 H3-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19111658 16127177
CBX8 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18927235 0805317105
APCS H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 3675579 8033412
RRP8 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H3C2 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11242053 5213683
H3C2 KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
H3C2 MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
H3C2 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H3C2 ORC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25689043 22398447
EED H3C2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 SIRT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15469825 18485871
H3C2 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 SUZ12 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
KDM6B H3C2 â—¼   DEMETHYLATION ✅ 2.0 0.8 Reactome 19451218 19451217
NCOA3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
SIRT1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19270680
RRP8 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
ATRX H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20211137 20651253
KDM4B H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22373579 8387631
APCS H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 3675579 8033412
SUV39H1 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H4C6 DNMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
H4C6 MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
H4C6 ORC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25689043 22398447
H4C6 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H4C6 KIF3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EED H4C6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4C6 PRMT6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18079182 11448779
H4C6 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4C6 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4C6 SUZ12 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4C6 SIRT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15469825 18485871
H4C6 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
SP1 H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7779811
H4C6 KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
KDM6B H4C6 â—¼   DEMETHYLATION ✅ 2.0 0.8 Reactome 19451218 19451217
HDAC1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10220385
HDAC2 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
NCOA3 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
KAT2B H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9880483
ORC1 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25689043 22398447
NOS3 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUV39H1 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
CBX8 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18927235 0805317105
RRP8 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
APCS H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 3675579 8033412
H3C14 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H3C14 MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
H3C14 KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 KIF3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RBBP4 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
RBBP7 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EZH2 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EED H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
SUZ12 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C14 SIRT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15469825 18485871
H3C14 KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
KDM6B H3C14 â—¼   DEMETHYLATION ✅ 2.0 0.8 Reactome 19451218 19451217
EP300 H3C14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11509556
CACNA2D1 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RRP8 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
CBX8 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18927235 0805317105
PHF21A H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20953165 8088874
ING2 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20953165 8088874
NOS3 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
ATRX H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20211137 20651253
CBX5 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19834512 7297014
APCS H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 3675579 8033412
EHMT2 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SUV39H1 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H3-3B TAF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20953165 8088874
H3-3B ING4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20953165 8088874
H3-3B REV3L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-3B ORC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25689043 22398447
H3-3B MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
H3-3B DNMT3L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19834512 7297014
H3-3B BPTF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20953165 8088874
H3-3B SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H3-3B KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
EED H3-3B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3-3B SUZ12 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3-3B RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3-3B RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3-3B SIRT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15469825 18485871
H3-3B EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3-3B KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
KDM6B H3-3B â—¼   DEMETHYLATION ✅ 2.0 0.8 Reactome 19451218 19451217
KAT2B H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 34811519 15616580
ZMYND11 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24590075 24675531
AGO2 AGO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16756390 0040210
AGO2 EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PKN1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1218925110 23223530
PRKACA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAMK2A AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NCOA3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16877447 20305690
MAPK8 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16306447
SIRT1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21775285
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
AR KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
AR KDM4C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23698634 20610535
AR MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14619959 20610535
AR SIN3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 16254079
EZH2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 23239736
KDM4C AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17277772 29207681
MAPK3 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK1 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
ASF1A EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19270680
ATRX POT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20211137 20651253
INCENP AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218018 16239925
EP300 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24229708 15138260
CBX1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ORC1 CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1009945107 20689044
CBX5 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YY1 CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19566924
CHAF1A FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
POT1 DAXX â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20211137 20651253
DDIT3 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18794136 19074988
DNMT1 RRP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17172825 18049164
DNMT1 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17172825 17584191
DNMT3B SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16371653 17584191
DNMT3B EHMT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16371653 17584191
MAPK11 ELK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9130707 9235954
MAPK14 ELK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9130707
ING2 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218757 16782091
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
ESR1 NOS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17921256 0704315104
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
PRMT6 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20047962
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
EZH2 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18980680 17584191
SP1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SUV39H1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
ORC1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN PRMT6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
RUNX1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16995417 12835475
SP1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15486968
SP1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12847090 5216518
ING2 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20574448
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
ING4 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PHF21A KDM1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15325272 16140033
PKN1 KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
KMT2A RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23817177 22012064
MAPK1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK1 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
RPS6KA1 MAPK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MAPK1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15778365
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
MAPK14 NCOA3 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16456540 5218295
MAPK3 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK3 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
SP1 PDHA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8476854
SUV39H1 PRMT6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SP1 YY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22553354
HDAC2 PHF21A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EED SUZ12 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MAPK8 MAPK9 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
CBX7 HDAC2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 19706751 22214847
DAXX H3-3B â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 24981860
CBX1 CBX3 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
ASF1A MCM2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
UHRF1 CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28803780 34079125
CBX5 AURKB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20562864 20231385
MYC CBX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CBX1 RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX1 EHMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
DAXX CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 34079125
CBX8 CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 34079125
MYC CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
DNMT1 CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12867029 17470536
DAXX CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 24981860
CBX5 EHMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20562864 24981860
CBX5 SUZ12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27634302 20562864
ESR1 CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
MYC CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
CTBP1 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15834423 21102443 16122695 35016035
CTBP1 EZH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27634302 31041561
MYC DNMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
EED NOC2L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 24457600
EZH2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27634302 26496610
KDM4B ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30418174 21502505
ESR1 SUZ12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 26389696
ESR1 KAT2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16260778 31527615
KAT2B KAT2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10373431 24981860
SP1 KAT2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16050810 15647279
KAT2B NCOA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 9346901 9445475 9267036
LACC1 SIN3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 27478939
MYC RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC TFAM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC NOC2L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYC RUNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
RRP8 NOC2L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CHAF1B RBBP4 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
AKT1 GSK3B â—¼   DOWN_REGULATES ✅ - 0.82 0.82 Signor 15829723
AKT1 GSK3B â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 23552696
CBX1 EHMT2 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CBX1 H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16415788 5218238
H3C2 CBX1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16415788 5218238
AKT1 MAPK14 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
RUNX1 CBFB â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 17431401 5219852
CBX5 EHMT2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
EHMT2 CTBP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 17967884 16702210 26186194 28514442 31041561
DNMT1 RUNX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15735013 28533407
HDAC1 EHMT1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
ESR1 KDM1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17289570 23403292 31527615
ESR1 MBD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 20300195
KDM1A EZH2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31130994 23455924
EZH2 SIN3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27634302 24981860 27705803
RBBP7 KDM5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24981860
CHAF1A CHAF1B â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HDAC1 UHRF1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CBX5 DNMT3B â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CBX1 SUV39H1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
AR FOXA1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CBX5 ATRX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10699177 20110566 15882967
EHMT1 CTBP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 12700765 16702210 26186194 28514442 31041561
DNMT3B EZH2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ESR1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21984853 31527615
EP300 ING2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16782091 16024799
ESR1 FOXA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23403292 25303530 28336670 27926873
ESR1 EZH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
MYC HIRA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21150319 23602572 29467282
CHAF1A RBBP4 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HDAC1 PHF21A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
DAXX HDAC1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
CBX3 CHAF1A â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
DNMT1 HDAC2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
DNMT1 EZH2 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
CBX5 H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 16415788 5218238
H3C2 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 20871592 8087215
H3C2 CBX5 â—¼   PROXIMITY ✅ 0.85 0.85 mint 25281560
EHMT2 CBX1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24981860 17962312 19706462 15200951 27705803
RUNX1 EP300 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16917507 14752096
EP300 MCM2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33742100 30110629 20808282
ESR1 MYLK2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21182203 25604459 21182205 31527615
ESR1 RBBP7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23403292 31527615 18577416 21182205
RBBP4 SP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12091390 16713569 12943729
HDAC1 RUNX1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MBD2 RBBP7 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
EHMT2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21258344 26028330
ING2 RBBP4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 16387653
MAPK3 RPS6KA3 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
AKT1 NOS3 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24379783
HDAC1 YY1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
DAXX DNMT1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
EHMT1 EHMT2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
MAPK11 MAPKAPK3 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
AKT1 AR â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CBX3 EHMT1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27705803 34079125
CBX3 CBX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
KDM1A CTBP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17967884 20547759 16079794 26496610 16140033 26186194 28514442 28947780 31041561
CTBP1 KAT2B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15834423 9824164 16122695
DAXX HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10669754 12140263
RBBP7 EED â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 12435631 26496610 26186194 27705803 28514442
HDAC1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16287849 26496610 23752268 28514442 26028330
EHMT2 KDM1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26751641 26028330
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
SUZ12 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26344197 22439931 24457600
MYC HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 17314511 30415952 20195357
ING2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 16387653 33961781
MYC KDM1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 23455924 32296183 29467282
SUZ12 RBBP7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27634302 24981860 20075857 12435631 35016035 26186194 31281901 24457600 27705803 28514442
ASF1A H4C6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
AKT1 CHUK â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CBX1 CHAF1A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MAPK1 MAPK14 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SP1 YY1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CTBP1 ZNF217 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
KDM1A ZNF217 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ASF1A ASF1B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
DNMT1 DNMT3B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
UHRF1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15361834 22411829 31782885 17934516 19800870 20037778
ASF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
H3C2 ASF1A â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 7219095 19498464
H3C2 ASF1A â—¼   PROXIMITY ✅ 0.88 0.88 mint 25281560
AKT1 NOS3 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ESR1 ASF1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21217774 31527615
AURKB AURKC â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15316025 31586073 27332895
MBD2 DNMT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10947852 27593931
DNMT1 EED â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16357870 22094255
SP1 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10651903 34252870 16478997 11030335 11517158 15647279 17623675 17906698 28425985 32115405 31536933 12200149 24530506 23714681 10362258 22415975 16734381 19062177 10899165
ESR1 GATA3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26153859 23403292 25303530
GATA3 HDAC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29453984 26028330 31409898
GATA3 KDM1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 35140242 26028330 31409898
SIN3A MBD2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24981860 10950960
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
BPTF RBBP7 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
KAT2A MYC â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CTBP1 KDM1A â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CBX5 CHAF1B â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EED HDAC2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
EHMT1 EHMT2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HDAC2 YY1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MYC GSK3B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16247449 20713710 19131971 21150319 31638140 29467282 11877389 33541412 14563837 8247524
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
HIRA ASF1B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 16980972 28514442 26527279
CBX5 SUV39H1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HDAC2 CTBP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17967884 11022042 18212045 16713569 10766745 28947780 31041561 16036112
HDAC2 DNMT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17967891 23708667 21670149 10888872
EHMT2 EHMT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 21258344 28698370 21430779 27705803 34588438 26028330
KAT2B EP300 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12888487 22384255 9267036 12419806 21413932 20870727 33051058 8684459
KDM5A ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11358960 31527615
GATA3 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 34026424 29453984 26028330 31409898
ING2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16728974 16387653 23752268 28514442 18193082
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
EP300 NCOA3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CBX5 CHAF1A â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
EZH2 HDAC2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
KDM1A PHF21A â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
RBBP4 SIN3A â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
DNMT1 GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B DNMT3L â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FYN GSK3B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
MYC GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
AR GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20127713 20610535 18687691
GSK3B AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15361837 15178691 14985354
CBX3 H3-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19111658 16127177 17540172
KDM1A H3-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17537733 15620353
H3C2 UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
H4C6 UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
H3C14 UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
H3-3B UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
UHRF1 DNMT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22064703 21268065 26065575 33170271 28803780 19800870 31322780 29691401 27045799 33465813 24782312 27049577 20613874 24368767 21045206 17934516 19943104 21745816 17673620 29268763 19798101
ASF1B H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
H3C2 ASF1B â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 7219095 19498464
H3C2 ASF1B â—¼   PROXIMITY ✅ 0.9 0.9 mint 25281560
H3C2 ING4 â—¼   ACETYLATION ✅ 3.0 0.9 Reactome 18381289 18623064 19187765
KDM4C H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 29207681 18022353
KDM5B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30246379 17909537
PRKACA H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11749379 9892015
KAT2B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34811519 16096646
SETDB2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20133783 20404330
KDM6B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24561908 20123895
KDM5A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30246379 18483221
KDM5D H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30246379 17909537
KDM3B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18022353 16603237
KDM4B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30759871 18022353
ASF1B H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11985607 12842904
MAPK14 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278789 10806218 12917630
CBX5 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19834512 17403666 19111658
FYN H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15537652
CHEK1 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18243098
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
FOXA1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24875621 18178153
NCOA3 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10965917 17108143 19305643
AR NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21273442 20610535 23689136
AR KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 16079795 22052438
ASF1B RBBP4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28514442 27705803 17353931
DAXX ATRX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 23329831 29084956 24981860 26496610 14990586 29937341 31628488 27029610 23222847 23135716 20147399 28875424 15252119 27872097 25416818 28875283 12953102 24651726 31631027 22102817 34162889
EZH2 ATRX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25417162 27634302 9499421
HDAC1 CBFB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
CBFB SIN3A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
CBFB PRMT6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
EHMT2 CBX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 17962312 22514736 15200951 27705803 34079125
CBX5 CBX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 15306854 17314413 34079125 20562864 11336697 16713569 19498464 27705803 21888893 20231385 20850016
MYC CBX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
PRKACA CBX3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16531993
MYC CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
DNMT1 DNMT3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24423239 16481298 20155458
SUZ12 EED â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
EP300 KAT2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23667505 23555303 21559432
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
NCOA3 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18484708 20181721 19491275 10490106 25728767 26166704 12554772 18645020 16923966 16331275 16713569 11376110 21182203 23403292 11050174 9192892 26487511 28844863 11353774 15145444 17158759 11389589 14966289 9346901 26153859 17646391 20392877 15383283 12630920 9765300 12714702 14766010 30418174
FOXA1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21572391 20501593 24290378
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
RPS6KA5 EZH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EZH2 MAPKAPK3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EZH2 KDM6B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23179372 22014533 23932971
PRKACA FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20658524
MBD2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10444591 33961781 10471499 12183469 12665568 27173435 24981860 21258344 17634443 26496610 11102443 23752268 28514442 11297506 27593931
SIN3A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12724404 24981860 14593184 26496610 11102443 17827154 10220385 14647463 9885572 15695521 12398767 26344197 21258344 9804427 16331260 12091390 9150133 11602581 10640275 12920132 9790534 17643391 12943729 19182791 25314079 12374985 28514442 26949739 10444591 11931768 11171972 17956988 12453419 15451426 23752268 11784859 18059533 20585571 9520398 11118440 17962807
RUNX1 HDAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HDAC1 PRMT6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
HDAC1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18634613 11486036 11940654
KDM1A HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21937684 34031383 21670149 19703393 24981860 16079794 26344197 21258344 20164337 9804427 32882276 12493763 11102443 12032298 23752268 28667074 26949739 34050636
KAT2A KAT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23667505 23555303 21559432
MYC KAT2B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 12660246 15572685
MAPK1 RPS6KA3 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PKN1 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 17251915 12761180
MAPK14 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15649893
SP1 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14561739 16452190 9295358
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
MYC SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SLBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PDHA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
SP1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7541039
RUNX1 PRMT6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
PRMT6 SIN3A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
SIN3A RBBP4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9651585 11602581 24981860 21258344 12453419 15451426 9150133 12943729 27705803 9150135 11118440
SIN3A RBBP7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17255935 9651585 24981860 12453419 15451426 26186194 11784859 27705803 28514442
SP1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23843607 20160399 23704280
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RBBP7 SIN3A â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
HDAC2 SUZ12 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
HDAC1 ING2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ASF1B CHAF1A â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
CHAF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PROXIMITY ✅ 0.91 0.91 mint 25281560
EZH2 EED â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
EED HDAC1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
BPTF RBBP4 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
ING2 SIN3A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CHAF1B H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24981860
H3C2 CHAF1B â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 7219095 19498464
H3C2 CHAF1B â—¼   PROXIMITY ✅ 0.92 0.92 mint 25281560
ASF1A RBBP4 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HDAC1 SP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
EED RBBP7 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ASF1A CHAF1B â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
ESR1 NCOA3 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
AKT1 GSK3B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
EZH2 RBBP7 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
MAPK14 MAPKAPK3 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
EZH2 RBBP4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
CHAF1A CHAF1B â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
RBBP7 SUZ12 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
SUV39H1 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
ASF1B HIRA â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
CBX3 EHMT2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
DNMT3B DNMT3L â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
ASF1B ASF1A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 24981860 22407294 26496610 12842904 34079125
HDAC2 KDM1A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
HDAC2 MBD2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
HDAC1 DNMT1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22274925 10888886 15870198 21670149 17707923 10615135 26794444 17967891 20613874 12473678 17934516 23708667 27593931
RBBP4 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 34518534 11302704 11102443 27705803 17827154 10734134 10220385 9885572 10471499 26344197 21258344 12091390 9150133 16713569 11602581 12920132 20127688 9790534 17643391 11470869 19686092 12943729 9150135 28514442 16189514 27068747 10444591 19703393 11171972 15451426 23752268 20585571 9520398 11118440 31435636
RBBP7 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 17255935 22939629 26496610 11102443 27705803 9885572 10471499 26344197 21258344 12920132 9790534 19686092 9150135 28514442 25885317 10444591 19703393 15451426 26186194 23752268
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
SIN3A HDAC2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12724404 16254079 12082111 24981860 17827154 22493095 9885572 12398767 26344197 21258344 9804427 12493763 14749338 12091390 12943729 25314079 26949739 12453419 15451426 23752268 9150134 18059533
SUZ12 RBBP4 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 27634302 24981860 20075857 22939629 35016035 15225548 24457600 27705803 31281901 28514442
EED RBBP4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ASF1B CHAF1B â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
AURKB INCENP â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 12925766
MBD2 RBBP4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ASF1B MCM2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
AR NCOA3 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MCM2 ORC1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MAPK1 RPS6KA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ATRX DAXX â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
AURKC INCENP â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
HDAC1 MBD2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CBFB RUNX1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RBBP4 SUZ12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DNMT1 UHRF1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ASF1A HIRA â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EED SUZ12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EED EZH2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
RPS6KA1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11584304 11583116 23331499 8250835 7980435 8524413 24931005 19346560 12054501 16039586 12147701 11035810 22615844 16543730
AKT1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 99.0 1.0 Omnipath 17428466 15207235 17145710 12052830 10729337 8250835 11756412 11923280 16914735 17623045 16697215 8524413 12054501 20398329 18372248 21506126 20028971 12040186 15808505 16543730 20138985 23331499 21303971 16009706 10385618 20214616 23180781 9373175 16039586 15829723 18988627 16282323 11577096 11035810 18669648 18216173 15169778 12851486 16123141 11882383 23109003 9065430 18691976 22094462 10949026 22710759 11715018 12459251 18636226 17192257 11254732 11278246 20858269 9812896 9582355 15023346 17680028 19369195 7945242 12900420 23552696 18387957 10722653 20832730 18570873 12147701 18505846 17052453 17693255 18218901
MAPK3 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16039586 28646232
PRKACA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 16543730 15845746 18691976 19836308 8524413 12054501 16039586 12147701 16522636 11035810 18669648
MAPK14 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26822034 17726008 21303975 18451303
MAPK1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16039586 28646232 18451303
PPP2R5D GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
GSK3B MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 73.0 1.0 Omnipath 17081983 18463697 21646472 30037819 26751215 25647305 2663470 20080742 19797085 30003124 16855632 12040186 18679417 11018017 23331499 29229669 16611981 21071413 24265759 20068231 10671551 16039586 17570479 16023596 29258530 12615961 18669648 21113395 22461507 19131971 8247524 16247449 20604938 19575820 15150404 22481935 23668310 19651622 17444818 23964270 20537194 22893788 27684546 24662831 25333250 20399964 11877389 14563837 18408012 17052453 18455992 15212693 16371461 11274345
CHUK H3-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12789342 2789342
CBX1 H3-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19111658 16127177 18438399
RPS6KA3 H3-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10436156
KDM1A H2AC6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
UHRF1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19798101 22064703 20210320 17673620 24368767 19800870 27049577 20613874 21268065 24782312 26065575 17934516 21045206 21745816 19308066 27045799
KDM4B H3C2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 23435229 21445275 20682797 23723241
DNMT1 H3C2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
GATA3 H3C2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
FOXA1 H3C2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
KDM1A H3C2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
ZNF217 H3C2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
NR5A2 H3C2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
H3C2 NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
H3C2 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C2 DNMT3L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19834512 21979949 16829525 15861382 17687327
H3C2 AGO1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16936726 22722852 25313066 16373483 21589992 24086155 17085592 22445173 18227514 18852463 21427083 22961379 24388755 22064859
H3C2 AGO2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16936726 22722852 25313066 16373483 21589992 24086155 17085592 22445173 18227514 18852463 21427083 22961379 24388755 22064859
SUV39H1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16409643 19442252 11242053 10949293
CHEK1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 18451105 20068082 23844048 12560483 18066052 20948546 21357687 18243098
KAT2A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19407812 34811519 20224553
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
EHMT2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19690169 17194708 22387026
ASF1B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11985607 17353931 15664198 27753532 12842904
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
EHMT1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20084102 19010785 20118233
RPS6KA5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20129940 10464286 15994958 14625384 10469656
MAPK14 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20626350 11278789
CBX3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15136563 20871592 20011120 24576085 19111658 16415788 26527279
PRMT6 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18077460 17898714
CBX1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 15136563 11882902 16622419 20871592 11242053 19111658 15960974 16415788 26527279
RPS6KA3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15994958 10464286 10436156 14625384
SETD1B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8680430 32546566 20210320
CBX5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16687578 16622419 20871592 20011120 25281560 26527279 19111658 16415788 19498464
AURKC H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12588998 14583461
AURKB H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11278789 19007248 17938195 10464286 16457588 12234980 12082625 21282660 15249581 10949293 15108802 16185088 14583461 12588998 15681610 17924679 16222246 15684425 12560483 11856369
SIRT6 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18337721 16439206 19408108
KDM1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16223729 20210320 18343668 20228790 15620353
KMT2A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12453419 20210320 24680668 29897600 31485071 20541251 24235145 20452361
ASF1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15664198 10759893 11985607
EZH2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18022353 15196462
ZNF217 H4C6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
FOXA1 H4C6 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
GATA3 H4C6 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
KDM1A H4C6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
DNMT1 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
NR5A2 H4C6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
H4C6 AGO1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16936726 22722852 25313066 16373483 21589992 24086155 17085592 22445173 18227514 18852463 21427083 22961379 24388755 22064859
H4C6 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H4C6 NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
H4C6 DNMT3L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19834512 21979949 16829525 15861382 17687327
H4C6 AGO2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16936726 22722852 25313066 16373483 21589992 24086155 17085592 22445173 18227514 18852463 21427083 22961379 24388755 22064859
MYC H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 12695333
ASF1A H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11985607 15664198 25416956 32296183 10759893
EP300 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19423655 11689053 16332960
KDM1A H3C14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
NR5A2 H3C14 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
FOXA1 H3C14 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
ZNF217 H3C14 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
DNMT1 H3C14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
KDM4B H3C14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 23435229 21445275 20682797 23723241
GATA3 H3C14 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
H3C14 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C14 AGO2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16936726 22722852 25313066 16373483 21589992 24086155 17085592 22445173 18227514 18852463 21427083 22961379 24388755 22064859
H3C14 NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
H3C14 AGO1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16936726 22722852 25313066 16373483 21589992 24086155 17085592 22445173 18227514 18852463 21427083 22961379 24388755 22064859
H3C14 DNMT3L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19834512 21979949 16829525 15861382 17687327
GATA3 H3-3B â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
KDM4B H3-3B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 23435229 21445275 20682797 23723241
DNMT1 H3-3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
ZNF217 H3-3B â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
KDM1A H3-3B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
NR5A2 H3-3B â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
FOXA1 H3-3B â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
H3-3B NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
H3-3B DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3-3B AGO1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16936726 22722852 25313066 16373483 21589992 24086155 17085592 22445173 18227514 18852463 21427083 22961379 24388755 22064859
H3-3B AGO2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16936726 22722852 25313066 16373483 21589992 24086155 17085592 22445173 18227514 18852463 21427083 22961379 24388755 22064859
PRKACA H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 14722118 15308689 14583461 16185088 10464286 12912980 12789343 15249581 15632059 15537652 12805238 15851689
AKT1 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12588998 12529330
MAPK3 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
RPS6KA1 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10464286 15994958 14625384
MAPK9 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12917630 15994958 11278789 20068231
RPS6KA3 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10464286 15994958 14625384
MAPK1 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
CHUK H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12588998 17643371
AURKB H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 28137420 19007248 10464286 16179389 12082625 16222244 15130946 11350965 14722118 16185088 14583461 12789343 15537652 15681610 12588998 15851689 17924679 15684425 12560483 10469656 11856369
RPS6KA5 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10464286 18508628 15994958 14625384
MAPK8 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
AR AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20589722 11278645 17896924 18687691 22740037 12621049 12063252 22970326
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
PPP2R5D AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18039929 19216069 10026142 10995457 18042541 20452955 18559511 18588945 16680151 16406523
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 20832017 18691976 23108403 17418864 20068231 12062056 15107605 17570479 19664995 18669648 26091525
AKT1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26553800 24492612 27521372 26216216 25949795 21151116 21565170
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
AKT1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17470458 18349820 29861848 16210317 21601007 17570479 11404460 22155408 12621049 14555644 11156376
AKT1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 22391560 24526064 29864144 34230470 16224021 26517694
AKT1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 23331499 17680028 20214616 17688959 20398329 16537363 17052453 19575820
AKT1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 70.0 1.0 Omnipath 12759249 20166139 11756412 10376603 11923280 12446767 16697215 11044445 20398329 18372248 11696579 16126727 16839566 15808505 20138985 20299462 10908731 20363286 11988487 11425855 20214616 23103584 11729179 16043647 17570479 12171920 25460366 27322328 11978735 15169778 11029403 25241761 19654415 10949026 18048761 11715018 12791703 24379783 18636226 9812896 23397142 17680028 10376602 12431978 10722653 20832730 18570873 25009123 17052453
AKT1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 15710601 12048203 25241761 19442713 11278366 10485711 15800029 19609947 17570479 17660512 18515365 19088076 10485710
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
AR PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12933667 10075669 9886819 15691881
AR KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18945670 20610535 11328859 23095762
MAPK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18511414 9725910 10318905
MAPK14 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 30644418 24424504 21820033 16282370
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
KDM1A AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17277772 16079795
KAT2B AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
FOXA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23260764 22722839 16713569 12750453
DAXX AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 27671201 17145710 15350595 15572661
NCOA3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 14966121 11747336 15563469 16713569 10965917 21047772
MAPK8 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24424504 21512132 21820033 16282370
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
MAPK3 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
MAPK1 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
ASF1A CHAF1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16980972 11897662
ASF1B CHAF1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16980972 17145710 17353931 11897662
AURKB INCENP â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
CHEK1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23321637 22024163 17276342
AURKB YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23226345
AURKB INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 18773538 20619651 26460953 16565220 21554500 19303298 18477699 33067654 27332895 22024163 15316025 24344188 20068231 19357306 22814604 19951914 15249581 25892238 16571674 27512725 11050385 12925766 18669648 15630414 18767990 18691976 17956729 20562864 21051298 32028528 19369195 19995937 20739936 16239925 32356865 20430883
CBFB RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 25678665 11179217 14729951 24522927 23333304 20195544 17431401 14752096 11276260 2845103 15331439 10856244 11742995 26598521 22498736
CHEK1 MCM2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 MCM2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 MCM2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHUK MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CHUK NCOA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 17145710 19651622 16135815 15808510 11971985 20068231 19413330 22505454 16964243 18669648 15383283 15302935
MAPK8 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 28532298 14567915 17496919 19591900 21372320 19788416 15708980 8608010 16984892 20512932 20220133 21438496 20054826 19616017 23762064 15611655
MYC DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15021909 18483244
MAPK11 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15187187 19436832 15140942 20506250 8650547 21614932 16393692 11274345
MAPK14 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15187187 19436832 11163539 23331499 15140942 20506250 8650547 21614932 16393692 17570479 11426938 16189514 11274345
DNMT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21655924 20946668 17172825 15746193 22975348 12789259 19001520 24058781 23242655 22558281
RBBP7 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
RBBP4 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
SUZ12 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
EHMT2 DNMT3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19308066
MAPK3 ELK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 9020136 9130707 26028036
MAPK8 ELK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 9020136
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
ING2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16782091 16024799
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
KDM1A ESR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
ZNF217 ESR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
NR5A2 ESR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
GATA3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17616709 20130088 20068169
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22052999 11029009 10690351 14742696 19914929
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23911789 19376833 16091743
RPS6KA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10949034 15528270 19925796 15461668 25336146 11139588 12118371 30034315 15059947 16076840 7491495 12093745 11432835 10411321 11507039 9528769 7838153
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
RPS6KA3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11139588 23936765 17570479 19925796 11432835 11507039 19112174 9528769 7838153
ESR1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26153859 25303530 10096242
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
EZH2 RRP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 24737471 19502792 21546904 22563434
MAPK14 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21902831 30022044 17570479 27494834 28067271
YY1 FOXA1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
GATA3 FOXA1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
FOXA1 HDAC1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
HMGB1 FYN â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12646658 15802534 19931333 22842346 26618107 27048821 27192565
FYN RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18156174 12601080
FYN MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15735648
GATA3 YY1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9016636 19139378 11486036 8917507
KAT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11804596 19407812 15522869 12660246
SP1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20130956 20144149 17882273 15647279
MBD2 KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23000163 21452283 24163373 23928305 19738071
MBD2 KDM6B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 24106268 23152497 24158144 20506217
KMT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 16510874
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
SP1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12220517 16797880 20506264 20121399 20882567 18372343 10727414 21170990 17889508
MAPK14 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15187187 21675959 18039929 12738796 11157753 22521293 17255949 11238443 11274345 12697810
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17081983 32814053 20385094 11532940 7601337 23331499 15342917 8939914 21071413 23047924 20068231 11335727 9687510 12618428 18988627 18669648 23519423 23109003 18691976 12594221 9915826 17906627 8202512 9430688 19651622 12832467 11500364 14966081 29997244 25730857 8387505 10411321 18212344
MAPK1 RPS6KA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 20506250 15547943 18267068 15302935 12697810 11940578 12414794 17117922 23331499 21071413 23047924 20068231 16393692 9687510 17255949 15187187 19541618 19565474 17052211 15568999 19651622 14578350 11018520 15684425 11994045 11274345
MAPK1 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21988832 18156174 12016217 25241761 12832467 23602568 8939914 10480933 9915826 17906627 10980595 10856237 19282669
MAPK1 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16046550 17015473
MAPK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19318349 20882567 16377629 18775330 8226933 14744793 16079281 11904305 9604935 15212693 14593115 8388392
MAPK11 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK11 MAPKAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15187187 21988832 18039929 26186194 23602568 12738796 11274345
MAPK11 RPS6KA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15187187 19436832 23331499 15140942 21071413 20506250 21614932 16393692 9687510 11274345
MAPK14 MAPKAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 23602568 10581204 23331499 21071413 12738796 26496610 16189514 25852190 15187187 8626550 26186194 25241761 17906627 9922370 18039929 11157753 31515488 11274345 23455922
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 NCOA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22147914 16135815 20068231 19413330 16456540 16964243 18669648 15383283 15302935
MAPK14 RPS6KA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 20506250 15302935 17117922 23047924 21614932 20068231 10922375 16393692 9687510 15187187 20936779 26186194 19940164 15140942 18813292 15568999 19651622 19436832 14578350 11157753 15684425 11994045 11274345
MAPK3 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 15342917 18039929 12832467 23109003 8387505 14966081 9915826 21071413 17906627 9430688 11335727 18988627 11532940 10411321
MAPK3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18463697 9155018 21071413 32482868 18988627 15210690
MAPK3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 32205409 20150555 21983342 11904305 14593115 18199680 8226933 14744793 16079281 19318349 20882567 22266860 28574228 21097497 8388392 32615164 16377629 19245816 18775330 9604935 15212693
MAPK3 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 18156174 25241761 12832467 8939914 9915826 17906627 10980595 10856237 19282669
MAPK3 RPS6KA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 20506250 15547943 15302935 12697810 12414794 17117922 20068231 16393692 19251839 17255949 15187187 19541618 19565474 18813292 17052211 15568999 19651622 14578350 11891214 11018520 15684425 11994045 11274345
MAPK8 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28831131 22266860 18199680 19245816 25398907 17570479
MAPK8 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 29578371 17081983 19007248 23434668 21540183 22622703 17924679 18187866 24296261 18838864 19413330 20027304 21471201 19107194 16964243 18669648 15302935
MAPK8 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19651622 10551811 17081983 18767875 20068231 91332050 1651323 1748630 16713569 11243879 18669648 15210690
MAPK9 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10551811 34160558 26235622 25893300 25438055 20140016 33928666 11243879
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
PPP2R5D MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
ZNF217 NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
NR5A2 NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
PRKACA NCOA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22505454 15383283
SP1 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12759366 19105596 15722551 18624763 12684688 9614091 10574932 10713142 15061658 12270858 15180995
PRKACA NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15319357 12522122 34204249 10376603 31923467 16839566 33429979 34026871 16946136 10908731 10671564 16270749 11729179 12171920 26132171 11978735 17572401 24379783 10376602 16873402
NR5A2 ZNF217 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
PRKACA PPP2R5D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9688562 17110335 17301223 29294329
SP1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12759366 16574895 16790435 9458366 9415398 12169688 10949931 12694408 11562358
PRKACA TFAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23201127
SIRT1 SUV39H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18004385 19218236
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368