Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RB1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671466 14527674
EZH2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18980972 21765901
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
H3C2 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3-3B RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
TBP TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7666533 17967894
KDM5A PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31374292
HIF1A PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18340011 19648120
EZH2 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24719098 22956625
RB1 HDAC1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
HDAC1 RBPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9694793
RB1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211419 10228159
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
HIF1A KDM5A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
HIF1A AVP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16507742 12691740
HIF1A TM9SF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25961573
HIF1A NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15699159
ESR1 AVP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11089536
EED H3C2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EED H3-3B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
RB1 KDM5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22615382 1119836109
EPAS1 KDM5A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
TBP BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9303434 9388207
RB1 TBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11094070 16713569
TBP NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 9649342
H3-4 GATAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C2 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3-3B EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
NR3C1 PER2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19805059
H3-3B SUZ12 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 SUZ12 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3-3B H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20211137 20651253
SAP18 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16189514 9150135
ESR1 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31527615 26389696
ESR1 SIN3B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16469706 31527615
ESR1 PGR â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
GATD1 RBBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20850016 26496610 26841866 33961781 24981860 26186194
MO4L1 RBBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20332121 17573780 33961781 24981860 26186194
RBBP7 KDM5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
RBBP7 PHF12 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26496610 26841866 33961781 24981860 26186194
HDAC1 GATD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 20850016 26496610 26841866 33961781
HDAC1 KDM5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 33961781 26496610
GATD1 HDAC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26841866 24981860 20850016 26496610
PHF12 HDAC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26841866 24981860 26496610
GATD1 PHF12 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20850016 26496610 26841866 33961781 24981860
PHF12 KDM5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26841866 24981860 26496610
PHF12 SIN3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26841866 33961781 26496610 24981860
MO4L1 KDM5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 17573780 33961781 24981860 26186194
GATD1 KDM5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20850016 26496610 26841866 33961781 24981860
KDM5A SIN3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17573780 33961781 26496610 24981860
MO4L1 SIN3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20332121 17573780 33961781 24981860 26186194 19553677
GATD1 SIN3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20850016 26496610 26841866 33961781 24981860
GATD1 MO4L1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20850016 26496610 26841866 33961781 24981860 26186194 22038470
KDM5A SIN3B â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
ESR1 EZH2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
RB HMGB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11748221 16189514
ESR1 RBBP7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18577416 23403292 21182205 31527615
HDAC2 HIF1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25241761 11641274
KDM5A TBP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7935440 16713569
KDM5A RARA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11358960 16713569
TBP HMGB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 8006019 9880542 16713569
ESR1 RARA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9717844 25303530 25604459
RB TBP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11094070 16713569 9242374
C11orf30 MORF4L1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
HDAC1 NR3C1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
EZH2 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 26496610 33961781 24981860 26186194 27634302 24457600
SUZ12 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 35016035 26186194 24981860 12435631 27634302 24457600 31281901 20075857
RBBP7 EED â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 26496610 33961781 24981860 26186194 12435631
RBBP7 SIN3B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 26496610 33961781 24981860 26186194
SUZ12 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24457600 26344197 22439931
EZH2 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10581039 24981860 21685935 26344197
HDAC2 SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 24981860 26344197 20075857
GATAD1 MORF4L1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GATAD1 RBBP7 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MORF4L1 MORF4L2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HDAC2 SIN3B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PHF12 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 23752268 11390640 26496610 26841866 33961781
RB1 RBBP7 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
EED HDAC2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MO4L1 HDAC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20332121 17573780 24981860 14966270 26344197
HDAC2 SIN3B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15935060 26949739 21258344 24981860 16464847
HDAC2 RB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10490602 19293945 11583987 11593423 10228159 17827154 9468139
KDM5A ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11358960 31527615
TBP ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9259327 16713569 31527615 11595744
GATAD1 KDM5A â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
PHF12 RBBP7 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
GATAD1 HDAC1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
EZH2 HDAC2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
RBL1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
RBL1 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
HIF1A CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19342889 20138114 19940121
VDR CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16518840 15064717
ESR1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17163418 17681750
TBP HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16705163 21840992 12612066
MORF4L1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11500496 16189514 12397079
RBBP7 RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11283269 7503932 2005966 10220405
HIF1A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17273746 11641274 16511565 21148070 24015760
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
HDAC1 RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10490602 16189514 15003538 11909966 15485920 10888886 11158299 11896613 11583987 10228159 9988677 10778858 11839806 22615382 19081374 12466959 26264872 9491888 10615135 16766265 15044952 17827154 22366686 12473678 10499802 23752268 10891495 9468140 11684023 10958676 21900881 29997244 9724731 10779361 9468139
HDAC1 SIN3B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 11959842 20585571 10357820 15935060 10444591 26496610 33961781 11102443 24951594 26344197
TBP FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22848139 7667110 1538403
ESR1 CD24 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18404683
ESR1 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664452 17556531 12710998
SUZ12 EED â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
PHF12 MO4L1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22038470 25416956 20332121 21440557 17573780 26496610 26841866 22244764 33961781 24981860 26186194 12391155 19553677
KDM5A RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22615382 8414517 7935440 11358960 15949438
KDM5A ME3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20644511 20406991 21604327
KDM5A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30246379 18483221
TBP RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9242374 10197586 9400991
RARA RBP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8530418 8288643 8015546
EZH2 SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21135039 21884980 27338022 18931660 28068325 23079660 24469040 19026780 21190999 26496610 26748827 24320048 33849069 35016035 27634302 29669287 18285464 20543829 18453536 31130994 21123648 20123894 24183680 27728805 25470042 12435631 22939629 16224021 23624935 24457600 26344197 20075857 15882624 23684459 31786184 31281901 23238014 26130719 19026781 27705803 22439931 27303043 31631027 24981860 33961781 19734898 31948940 18483221 21378168
MO4L1 RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 12397079 11500496
KDM5A MORF4L1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
HDAC2 SUZ12 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
HDAC2 PHF12 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
RBBP7 SIN3B â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
EZH2 EED â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
EED HDAC1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
MORF4L1 RBBP7 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
KDM5A PHF12 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EED RBBP7 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
HDAC1 RB1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
HDAC1 MORF4L1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
HDAC2 MORF4L1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
EZH2 RBBP7 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
HDAC1 PHF12 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
MO4L1 HDAC1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 17573780 20332121 26344197
ARNTL PER2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RBBP7 SUZ12 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
RB1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 6550000 10779361
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
MORF4L2 PHF12 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
EZH2 HDAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 21685935 15520282 10581039 24771265 31130994 22439931 26344197
HDAC1 RBL1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10490602 9724731 16189514
HDAC1 SIN3B â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
HDAC2 RBBP7 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 20388487 27705803 21258344 33961781 24981860 26186194 15451426 12493763 9885572 26344197
RBBP7 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19703393 10444591 21258344 11102443 9885572 17255935 10471499 26496610 25885317 22939629 9150135 23752268 9790534 27705803 33961781 26186194 19686092 15451426 12920132 26344197
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
EED HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10581039 11124122 26496610 22439931
EED HDAC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30737378 10581039 11124122 24981860 24457600
EED SUZ12 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 29379173 27338022 19026780 26496610 35016035 27634302 15385962 15225548 18285464 20543829 12435631 31786184 24457600 31281901 20075857 19026781 21078963 27705803 22439931 28320739 33961781 24981860 23280602 18483221
EED EZH2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21135039 9584197 9742080 31948940 29379173 27338022 18931660 28068325 33754075 11158321 9584199 32296183 22897849 17937919 19026780 21190999 26496610 24320048 33849069 27634302 15385962 16314526 29669287 15225548 18285464 10581039 21123648 12435631 31786184 23624935 24457600 20075857 15882624 19026781 21078963 22094255 22439931 28320739 27705803 31527584 24981860 33961781 23280602 26344197
MORF4L1 SIN3B â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PHF12 SIN3B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
MORF4L1 PHF12 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EED SUZ12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RB1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
TBP CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15280358 17130157 17996705
RBPJ CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11432830 11306509 15866158 14670925
EZH2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21572997 21546904 24074410 21629038 22956625
NR3C1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11080152 17989362 9873044 10413457 15466360 12969137 9442037
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
RARA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10356361 24821728 21383775
HIF1A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15071503 15190211 10559391 20043814 21362093
VDR CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17680631 23087083 16434701 21088000
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
CDKN1A RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10498883 9315635 17303408 10486249 16236519 11520855 15279786 9190208 7575488 10385618 9736735 7736585 19075565 18590585 20068082 9425340 18786381 17660363 10778858 17556661
RB1 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
HIF1A HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11592948 19828020 20819234 17389506 10600883 11356853 15805230 18799519 17122584 17996129 20526373 15050899 20833713 14970910 19254160
ESR1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21411498 12122114 21693539 18519947 16690106 10805720 19360348 23409030 18754863
HIF1A TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18754863 15048086 17699105 16961934
RBPJ PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17245125 19479935 24113181
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
NR3C1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15826950 16762839 18762022 18028994
HDAC2 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HIF1A EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20513003 18174278 16924414 19030186
RB1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15674338
EZH2 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 22179855 22312437 21512140 23933322 24737471 23932971 23918806 19053175 19502792 24928441 23424038 24032713 24474760 20634887 18704159 24652950 22072987
KDM5A FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21604327 20644511 20851996 21348942 20406991
ESR1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8300756 8912864 8732679 11038749 15831516 15870697 10076999 9626663 18414489
ESR1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 12829318 12554765 12446585 11000528 15019994 8043503 23027806 9058379 9717846 18414489 12706304 10835496 16293641 18784357 12761896 8145766 22543272 15743834 8530508 10894148
PGR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 22396492 16168121 12612073 11000528 18988627 26153859
ESR1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 17641689 15831516 9717844 9841885
EED EZH2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARNTL PER2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20576619 23620290 17660446 20215567 19168071 22750052 21960634 24051492 23469106 20852621 11441147 11798163 22039518
PER2 ARNTL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18662546 20159955
EZH2 ME3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 22179855 22312437 23788032 24018208 21512140 24737471 23932971 20368440 24928441 19053175 23424038 24032713 20634887 18704159 24652950 22072987
EZH2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18022353 15196462
NR3C1 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 8218210 8213259 9388207 2038339 9303434
VDR BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17786964 11891855 15299011 8119880 11278818 15456860 7705332 7981122 8382695 8076631 8920918 1664043 12697832 20227497 8990171 10677586 21964930 9257196 15225783 2175914 22405968 1353882 17218095 8014199