Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CCND3 E2F5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11157749 9144196
MYOD1 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10373569
CDK6 CCND3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
E2F3 CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12611887 18319725
E2F2 CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12611887 18319725
ABL1 SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDC27 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
JUN ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9746785 15145216
AHR MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114727 16091746
HDAC3 BAG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19595997 7216159
RAF1 BAG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8692945 5221106
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
JUN BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16229810 17434164
MYC CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F5 CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21374739
E2F1 CBX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
E2F4 CBX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
CDC27 CCND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0913813107 20439707
CCND1 E2F5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11157749 9144196
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
E2F3 CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8033208 7958856
CDK2 MCM7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
CDK4 E2F5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11157749 9144196
CEBPA CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11867521 11684017
CDK6 E2F5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11157749 9144196
CEBPA MYC â—¼   DOWN_REGULATES ✅ - 2.0 0.8 ACSN 11340171 20581311
HDAC1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16431920
SP1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10373535 12049196
CEBPB KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23456364 17301242
CEBPB E2F4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16959612
E2F1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15867357
E2F2 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7958836
E2F1 MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14990995
E2F1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067
HDAC1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17980157 18319725
E2F1 E2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15014447 18319725
E2F1 RBBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
E2F2 MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14990995
E2F2 MCM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 14990995
E2F2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11564866 18319725
E2F4 E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F3 MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14990995
E2F3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11564866 18319725
E2F3 MCM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 14990995
E2F4 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067
E2F4 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 RFC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 16135806
E2F4 RBBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
E2F4 MCM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 14990995
E2F5 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17132729
E2F5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12150994 18319725
HMGA2 E4F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14645522
SP1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12847090 5216518
TAL1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
TBP JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17074809 21106530
PML JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671405 10620019
TAF1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17085686 9285713
PML MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
MDM2 PML â—¼   COLOCALIZATION 2.0 0.8 intact 5216620 12915590
MDM2 MDM4 â—¼   COLOCALIZATION 2.0 0.8 intact 17159902 5219425
MYC TRAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11139609
TAL1 RBBP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
SP1 TAL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8058326 9786909
PPIA RB â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12210730 16189514
RB HMGA2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 16766265
ANDR KAT2B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11328859 10779504
CDK2 P53 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 10884347 10747897 12064478 10348343 25241761 19556892
P53 LMNA â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 29568061 30419336 25144556
TFDP1 E2F4 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 24981860
CBX5 RB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15485920 11484059
RFC5 RB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SSF1 RB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CC062 RB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
TAL1 RB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19497860 10866689
RB ANC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17187060 33971196
ANDR ZBT16 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23798432 19762545
ANDR CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33640491 34585037
CDK9 P53 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17942552 16741955 16552184
JUN P53 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 31182485
JUN GBLP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 21860413
RBBP7 SUV91 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11788710
MO4L1 LMNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24623722 17573780
MYC PP1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
CTBP1 DYR1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26186194 35016035
RFPL2 DYR1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
DYR1A EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30137413 23602568
MYC AATF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
EP300 ATF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24069158 10327051
DNMT1 CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12867029 17470536
CDK2 E2F4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25852190 33961781
MYC CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
CTBP1 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15834423 21102443 16122695 35016035
MYC DNMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
JUN HDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 17056544
HDAC1 RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26496610
MYC JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
SP1 KAT2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16050810 15647279
LIN9 TFDP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 17531812
LIN9 TFDP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 17531812
MYC RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC PHB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
MYC RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC TAF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 26496610
MYC RFC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
TFDP1 RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
TGM2 RB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 9315663
LAP2A RB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12475961 16713569
CDK13 RB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RFPL2 RB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TFDP3 RB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RING1 RB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11583618 16189514
ANM2 RB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16616919
RB CEBPA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18239623 10082561 15107404
RB GBLP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 12761493
UBF1 TBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16713569 8552083
MYOD1 SMCA4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 22068056 15870273 20195544
SMCA4 HDAC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20596014 12192000 19081374
BRCA1 MAT1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22493164 15282296
MO4L1 RBBP7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 26186194 17573780 28514442 20332121
MO4L1 KDM5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 26186194 17573780 28514442
ARI4A RBBP7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 11283269
CC062 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 35016035
BRCA1 CDK9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22990118 28278048
CTBP1 PRDM2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 35016035 26186194 28514442 31041561
TFDP3 E2F3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TFDP3 E2F4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LIN9 E2F4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 17159899 17563750 17531812 17671431
RBBP7 KDM5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24981860
RBBP7 LIN9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24981860
MYC LMNA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EID1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
BRCA1 CDK2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
KAT2B MDM2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PHB RAF1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CBX4 RB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11583618 16189514 30317550
HDAC3 RB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10490602 16189514 12479814 10958676
CTBP1 RB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 11583618 35016035 26186194 16713569 28514442 16189514
SP1 RB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10850422 11896613 7732011 11158299
RB ZBT16 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18504436 15949438
RB FZR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17187060 33971196
RB SIR1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17620057 16892051
RB KAT2B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19249677 15044952
RB P53 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20871633 8083962
TAF1 P53 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10359315 15053879 16713569
TF3B P53 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 8943363 16189514 16713569
CDK4 P53 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28218424 28205554 28628118
P53 MK14 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17172861 21675959 21050851 15642743 10581258 20213747
MK14 CDK4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23455922 28205554 28628118
SUV91 DNMT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12711675 17085482
UBP4 PPIA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23022198 29396555
MYC FZR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21150319 28205554 28628118
HDAC1 ARI4A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 10490602 26496610 11283269 23752268 28514442
DYR1B EP300 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23602568 32707033
CDK2 TFDP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25852190 33961781 9199321
CEBPB SP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12665574 12847250 16651265
E2F1 E2F3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 35140242 24981860 20106982
EID1 MDM2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11073989 24167073
HDAC2 PML â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
LMNA RBBP4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25948554 19734887
E2F3 TFDP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
DNMT1 HDAC2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
JUN PML â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
LIN9 RBBP7 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
RB CCND3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9003773 16782892 17972097
DGKZ RB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16286473
ARI4A RB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10490602 21148318 8414517 11283269
RB HMGB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16189514 11748221
ANDR EP300 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28549433 34585037 23518348 10779504 18487222 23172223 27903893 16713569 24480624 32668201
HDAC3 SUV91 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11788710
E2F1 SIR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16892051 19188449 24112038
MYC HDAC3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18483244 31155734 22002311 23079660
TAF1 JUN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11316804 16713569
KDM5A TBP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16713569 7935440
RBBP4 SP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12091390 16713569 12943729
CEBPB EP300 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
E2F1 EP300 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
BRCA1 CCNA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9244350 10373534 16713569
SNPC3 RB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16189514 11094070
MK14 RB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11566021 20871633 17380128 16945434
MAT1 RB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16189514 11113200
RB ID2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 7926730 11034201
RB TBP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9242374 11094070 16713569
SMCA4 PHB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15141164 12065415
CDK4 PP1A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17274640 22939629
CDK2 FZR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 33961781 23670162 12560341 11340163 26083744 23972993 33306668
SIR1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 18823944 20042607 23382074
KAT2B CCND1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10318892 11328859
CDK4 CDK13 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23602568 26496610
CDK2 CDK13 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23602568 26496610
RING1 E2F1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11583618 27705803
TBP HMGB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9880542 8006019 16713569
ID2 MYOD1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9242638 21209940
MYC TBP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15723054 16713569 8755740
PSD10 RB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10613832 30109252 12525503 11900540
BAG1 RB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12845674 16189514
MDM4 RB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16510145 25703327
DNM3A RB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11350943 23280764
MOFA1 RB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11500496 12397079
RB ATF2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 1641004 11566021
RB EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17620057 11433299 31753913 16878158
RB CDC27 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 7756179 17187060
ANDR HMGB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9671457 11748221 16713569
ANDR TAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33640491 20181722
UBF1 TAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12498690 16713569
MYC UBF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 29467282 20195357
P53 HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10777477 20388487 20190809 14976551 21344396 17827154 17805299 22493095
P53 SP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21325822 21831840 12665570 15674334 15710382 23650532 16713569 9685344 8463313 20570896 16740634 18765668 14710355 19846904 15574328 11384995 9492043 28000777 15790310
P53 ABL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10713716 16713569 10629029
SIR1 SUV91 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18004385 19218236
DNM3A CBX5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12867029 19834512 17470536
PSD10 CDK4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17881001 16189514 11779854 11900540
ZBT16 HDAC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15467736 24821727
SP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12706836 14710355 16713569 10720440 17766039
CDK4 BRCA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9244350 16713569 17334399 12509456
MYC CDK6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22094256 28205554 28628118
CTBP1 KAT2B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15834423 9824164 16122695
KAT2B E2F1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 24112038 19188449 15123636 24502362 23001041
E2F4 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9724731 23060449 9858615 21102443
E2F4 LIN9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HDAC1 E4F1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12730668 21666599
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
HDAC1 TFDP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27705803
MYC HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 17314511 30415952 20195357
TBP MDM2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9271120 9388200 16713569
MDM2 PML â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CBX4 CTBP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CDK9 MYC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CCNA1 GBLP â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 15159402
CCNA1 E2F1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16774918 10022926
UHRF2 RB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27114453 21952639
THOC1 RB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 7525595
P55G RB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12588990 16189514
PRKRA RB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 9010216
LIN9 RB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15479636 15538385
RB MYOD1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11285237 8381715
RB E2F5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12502741 16360038 24981860
RB SNPC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 11094070
SP1 ANDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15661808 10809237 9535906 17984071 23369005
UHRF2 P53 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22902639 21952639
RING1 P53 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29187402 22907436
SMCA4 HDAC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14559996 20596014 11238380 12192000 20460684 16800816 19081374
SUV91 CBX4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22078878 12101246
DNM3A HDAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11350943 19786833
DNM3A MYC â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19786833 15616584
MYC SIR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21807113 22190494
DNMT1 SIR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21947282 22094255
SIR1 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20660480 19047049 15632193
AHR EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17392787 21988832 10999956
AHR TBP â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15641800 8794892 16713569
CTBP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11751867 10196224 16713569 21102443 31636387
EP300 CCND1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10567390 15951563 11788592
MYOD1 CDK4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10601020 10022835
CDK4 CDK6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 28205554 28628118
MYC CDK9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17700062 12944920 30415952 26687678 19818711 11673469
CEBPB CEBPA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 1840554 15751966 20102225
SP1 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10651903 34252870 16478997 11030335 11517158 15647279 17623675 17906698 28425985 32115405 31536933 12200149 24530506 23714681 10362258 22415975 16734381 19062177 10899165
TAL1 HDAC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19497860 16407974
PML HDAC3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 11259576
EP300 MYOD1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
KAT2B MYOD1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HDAC2 RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9468139 11593423 11583987 10228159 10490602 17827154 19293945
ANDR RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9813067 16964284 16713569 9675141
ENC1 RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16306221 9566959 16189514
E2F3 RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19249677 8246996 7739537 24981860 8832394 10779361 17380128 31130363 8657117
UBP4 RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11571652 11571651
MYC RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29467282 7838535 30415952 28205554 28628118
E4F1 RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10869426 16189514
PRDM2 RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9223517 7538672
UBF1 RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11042686 7877691
FRK RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7664264 16189514
SMCA4 RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17666433 15485920 7923370 12434308 23438604 9128241 10778858 19081374
TF3B RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10330166 9169441 11997511
TRAP1 RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9312071 8756626
DYR1B RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23602568 32707033
SUV91 RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11533237 11484059 16189514
RB PAI2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16397580 16189514 12944478
RB COM1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22773103 9721205 10779361 17214969 16581787
RB TFDP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16360038 7739537 26186194 28514442
RB PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9448006 16189514 21205865
RB TFDP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16360038 24981860 7739537 27705803 17187060
RB JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9545246 10026157
HDAC1 ANDR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 34585037 11994312 26468294 15835920 16713569 15640443
ANDR BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11085509 11016951 16713569
ANDR HDAC3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16469706 33640491 12943985
ANDR SMCA4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19762545 34585037 14966121 33640491 18487222 28611094
PRKRA P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 9010216
MYC P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28205554 28628118
P53 E2F1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24076372 11739724 8557038
P53 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14976551 20075864 17827154 19011633 10521394 16697957 10777477 16107876 11099047 32494626 16959611 11313951 12426395 18765668 22266186 19303885 25241761 26539911 20633551
SP1 SMCA4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11018012 15317818 12192045 20969766
MCM7 MAT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11056214 16189514
MO4L1 HDAC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 26344197 14966270 17573780 20332121
DNM3A DNMT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29691401 12145218 21406692
PSD10 MDM2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17904523 18332869 16023600
FZR CDC27 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21768287 29700288 11340163 23160376 26963853 9637688 32345958 23670162 12097298 21186364 12797865 17187060 32152539 17609108 25306918 22014574 33306668 12956947 16479161 24100295 23029392 9734353 21986944 20395298 24811168 28514442 30498084 17942546 20663873 21241890 9811605 32076268 18372912 18662541 23972993
CTBP1 COM1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9535825 10196224 26807646 16287852 31636387
BRCA1 ABL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12024016 17352427
RBBP4 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10220405 26831064 16713569
CCND1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9244350 16713569 17334399
E2F4 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9244350 21102443 16713569
HDAC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10220405 21102443 16713569
HDAC2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21946536 10220405 16713569
HDAC3 CCND1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16461912 20484017 12048199 15558026 15713663
E2F1 CDK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11245432 7969176 8458319 1530885 9199321
MYC CDK4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22094256 28205554 21988832 28628118
HDAC2 CTBP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17967884 11022042 18212045 16713569 10766745 28947780 31041561 16036112
HDAC2 DNMT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17967891 23708667 21670149 10888872
TFDP2 E2F5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
KAT2B EP300 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12888487 22384255 9267036 12419806 21413932 20870727 33051058 8684459
PML HDAC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18644863 18073335 25812002 11259576
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
SP1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25879517 16478997 17215518 16713569 33572115 10506225
TBP JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7685215 7848298 16055710 16713569
PML JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10620019 16916642 9671405 15626733
JUN MYOD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 1310896 16713569 8380166
TAF1 MDM2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9388200 16713569 17237821
MYC PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17146439 21150319 32592588 30415952 15735755
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CCND1 CDK2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CCND3 TFDP2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CCND3 E2F4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CCND3 TFDP1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
E2F1 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12611887 16300731
CCNA1 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9139732 10022926 16189514
HDAC1 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9724731 15485920 10228159 12473678 26264872 10891495 17827154 22366686 10958676 12466959 9468139 21900881 11909966 11839806 11158299 10499802 15044952 19081374 9491888 15003538 11583987 10888886 11896613 16766265 10490602 10779361 16189514 10615135 22615382 9988677 10778858 9468140 23752268 11684023 29997244
AATF RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16189514 12450794 10783144
CDK9 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8170997 8870681 12037672 9258347
MO4L1 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11500496 16189514 12397079
RBBP4 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11283269 8350924 11470869 21689726 7503932 16189514 10734134
PA2G4 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19946338 16189514 11268000
KDM5A RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22615382 7935440 11358960 8414517 15949438
E2F2 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8246996 16360038 7739537 24981860 8832394 17380128 31130363 8657117 12502741 16189514
CDK4 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17015477 10486249 15169570 9315635 15695403 16205633 17053782 11287611 17873913 22094256 8867812 12190313 30833542 15147269 19225156 16878158 11900540 12509456 8449399 11971966 15003538 23543736 9003781 19767775 9139732 10202152 12519773 8647086 24292678 11306463 10198259 16326706 9190208 16189514 8756624 16985050 9199321 9464540 12949733 15922743 8626527 12676926 16962592 11254678 15241418 19556892 15998794
ABL1 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7828850 9071815 8242749 8626527
RBBP7 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10220405 7503932 2005966 11283269
TRIPB RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9256431 16713569 16189514
TAF1 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11126356 9242374 16713569 9858607 7724524
EID1 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11964378 11073989 11223246 11073990 15806172 16189514 15044952
E2F4 RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10869426 9380698 16360038 24981860 9501179 8657117 7958924 12401786 9858615
DYR1A RB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 30137413 23602568 32707033
RB DNMT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11847125 10888886 23280764
RB CCND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15485920 21242975 10491434 10486249 9178893 31217276 8867812 21654808 8449399 15681588 8490963 8662825 9003781 9139732 8647086 11593423 11126356 12676926 9823309 9190208
RB MDM2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21990374 16510145 16374512 10078201 11433299 15485814 9003773 25703327 20871633 33185004 16337594 7791904 15044952
RB RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15485920 21139044 10486249 9819434 16189514 19058874 10523633
RB LMNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16189514 8058329 30419336 8278403 29997244 31467278
RB BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11521194 10220405 10518542 16713569
RB E2F1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10869426 15485920 8255752 16374512 16360038 35140242 9400991 9315635 24981860 21085491 16496386 11090181 31130363 9501179 25257171 10891495 19249677 11713253 15837424 18216119 16249186 12096339 19477924 20871633 22768064 9632788 11839806 12502741 8458319 10499802 7958924 1388726 10207050 18391203 7828850 9219533 8449399 22078878 16766265 23472054 29521627 15485814 30867845 15619620 12963846 12947005 17380128 11470869 12397079 8657117 12598654 9422723 15670817 9553123 12401786 28074012 28542143 7739537 8626527 8346196 11583618 8896460 8816798 9125176 9468140 19058874 8230483 10393912 23001041
RB PHB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16964284 16189514 24380853 10523633 10376528
RB MCM7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9566894 12519773 16912045 9705868 16189514
PA2G4 ANDR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15583694 9565586 12165860
BAG1 ANDR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11278763 14517289 9565586 16713569
ANDR CCND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16461912 10344732 15558026 16713569 11328859
ANDR JUN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9211894 33640491 8798722 16713569
ANDR GBLP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12958311 32814769 16713569
MAT1 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 30477538 9372954 16713569 16189514
SMCA4 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17666433 11950834 21900401 18303029 19448667
KAT2B P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20589832 17189186 16537920 14614455 12501250 10891493 17977830 9744860 19680552 10490106 15965232 9891054 16959611 16678111 12068014
E4F1 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12446718 16713569 17110336 16652157 16189514 10644996
TBP P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7799929 8083962 1465435 12379483 10601022 16713569 11313951 8395834 8405994 9349482 10359315
EP300 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29706626 25156994 12724314 23728348 16543236 12501250 9652736 9194564 18243116 9194565 19339993 16678111 16611888 11359905 11782467 12162806 14612423 14759370 15186775 15664194 9288740 23402884 17452980 24157709 9891054 12499368 19234109 27818144 16537920 17977830 15295102 10518217 16713569 26625199 16928824 11070080 17906639 23870121 23796514 15558054 17438265 25867071 17189186 18485870 11907332 15542844 19217391 32807901 16438982 31167125 15337767 10490106 22731250 12690203 25288747 18612383 23329847 24821727 26302407 9809062 16959611 22074660 19218448 16782091 23880760 33196849 25753752 28757384 18391200 16024799 25651062 16135789 22013068 11433299 9744860 10601022 21187340 11804596 23307557 10942770 15509808 20234175 21471221 26229107 19805293 22266186 15965232 23010591
MDM4 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 31462704 10827196 19255450 22745160 23671280 31066983 10075736 10629057 11528400 15604276 24445145 19521340 19075013 12370303 30598450 21965653 19432880 16024788 31152661 21088494 22807444 17301054 30832340 17875722 16713569 20724842 28628118 16227609 30672125 25464845 25825738 22266850 24659749 20515689 21075307 20174603 18316739 17110929 20705607 10608892 24127580 29023092 26876197 24667498 9226370 18677113 27114532 28514442 22374672 17080083 8895579 12393902 29523541 32511789 30045945 19305137 23028042 18485870 11223036 26148237 25609649 19153082 26186194 21925390 28205554 23946421 28487147 15916963 12874296 25961923 27249653
P53 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14978302 9582019 14710355 21742769 18501503 9482880 14636569 9926942 16677609 26140185 19509300 15571721 16713569 16969499 31073355
P53 TFDP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8557038 8816502 16713569 16189514
P53 SIR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18235501 17964266 18235502 15205477 21245319 11672523 18753379 21149449 22735644 12006491 22389628 22689577
P53 PHB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14500729 20134482 16713569 16319068 24380853 16189514
P53 PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21057547 20972456 11704853 16007146 14976551 25241761 15375079 11025664 22869143 12006491 16713569 12915590 11080164 16189514
MYC SMCA4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14559996 17353931 29467282 11839798 30415952 28205554 28628118
CBX5 SMCA4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12411497 20011120 20562864 15882967 19498464
SMCA4 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10943845 23438604 16713569 15034933 26831064
LAP2A LMNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16339967 12475961 26496610 10984438 19727227 24623722 30419336 22412018 16713569 29568061 24927568 16247757 28902428 34079125
SNPC1 SNPC3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9003788 32296183 26186194 28514442 16189514 11056176
MOFA1 MO4L1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11500496 28514442 27107012 33961781 32296183 17008723 24981860 17353931 22038470 16407074 30217970 12397079 26186194 17573780 25416956
ZBT16 PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9294197 11175338 16189514
ZBT16 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15467736 19648967 24821727 16024608 32814053 9765306 9627120 11865059 26264872 16189514 29997244 23898169
BRCA1 PP1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12438214 22990118 17511879 25056273
ANC2 FZR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12956947 26083744 16287863 25043029 33971196 9811605 32905768 21135578 28514442 33306668
ANC2 CDC27 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21768287 22280307 16364912 22939629 25043029 27114510 32152539 25306918 10922056 20360068 12956947 22193957 14657031 17443186 26811472 27120157 16648845 32076268 26083744 21043528
BRCA1 COM1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10764811 29513652 11689934 18285836 10910365 16843262 26387952 19369211 29656893 17525342 31636387 31932421 9738006 25252691 30257991 16818604 25659039 21908405 25310973 19452558 14578343 10196224 17525340 23416467 9811458 34408138 22231403 27454289 11739404 28132842 20351172 24085845 26446986 15485915 25184681 18171670 28398198
ABL1 MDM2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12110584 25624478 16702947
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
ABL1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26603102 25219501
SP1 ATF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2145272 12760745
BAG1 RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11231577 16189514 8692945
MYC BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11916966 9788437 20215511 30415952 16713569 12646176 14612409
CDK2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31270457 8764100 16713569 9244350 10373534
RBBP7 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11394910 10220405 11746496 16713569
EP300 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10655477 21212407 19887647 22787115 16713569 11782371 21102443
JUN BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25609649 12080089 16713569
E2F2 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17106239
DNMT1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19943104 22197621 20631324
E2F3 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17106239
E2F5 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17106239
E2F1 CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12629508
MYC CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
TAF1 CCND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9926939 11126356 16713569
CCND1 E2F4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CCND1 TFDP2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CCND1 TFDP1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CEBPB CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22242598 11162569 12810706
E2F4 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10594784 7929342 9584162
UHRF2 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21952639
UHRF2 CDK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15178429 33876395 21952639
CDK2 CEBPA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34002296 11684017 15107404
CDK2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11598016 19450264
CDK2 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12006580 11420722 9315635
CDK4 TFDP1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CDK4 TFDP2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CDK4 E2F4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CDK6 TFDP2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CDK6 E2F4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CDK6 TFDP1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
SP1 CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12840223 11297539
CEBPA E2F1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12869508 11340171 12702500
CEBPA THOC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17242690
MYC CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12873812
CEBPA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12873812
EP300 CEBPB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9343424 14630807 12471036 28428115
CEBPB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21098707 20581311 16585579
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
E2F1 DNMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24502362 17575144 15867357
E2F4 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14576826 10208422
E2F1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10914734 20837136
EP300 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10753885 15123636 15126619
SP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10547281 8657141 10850422
E2F3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
E2F4 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
E2F1 MCM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18328430 18319725 14990995
E2F1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 18319725 90001421
TFDP2 E2F4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 16360038 32296183 10090723 26186194 9501179 28514442
E2F4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11564866 12150994 18319725
EP300 TAL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11118214 10490830 11756538
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
SP1 HMGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10558886 10471823 11802722
MYC KAT2B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 12660246 15572685
MYC LMNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC MCM7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 30415952 17314511 29467282 17353931
MYC MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MDM4 MDM2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26720344 33961781 27621617 26359458 10827196 10629057 24755078 23671280 22902369 22745160 22333590 15604276 20484049 18566590 12370303 30598450 31796886 10218570 19432880 34551723 12483531 29524278 17159902 27777309 12860999 27215386 11606419 18219319 17301054 19683495 25512388 20724842 28628118 16227609 22493164 20473904 25384516 26001071 25825738 22266850 29057323 25809483 25703327 32427989 20705607 10608892 31024344 19619542 21988832 29262653 25659040 29523541 28514442 27617579 29295817 33985974 12393902 16055726 23028042 24813712 22120712 32300648 32075226 21925390 17616658 28205554 23946421 19838211 25105592 12874296 25961923
TAF1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9388200 17237821 10891494
TAF1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9388200 17237821 16713569
MYC RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28205554 17314511 28628118 9315742
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
SP1 PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24728382 21360626 16713569 9819401
CCND3 CDK2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CCND1 CDK6 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
RBBP4 SUV91 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 11788710 16189514
E2F2 TFDP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HDAC1 SP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CBX4 RING1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
MDM4 MDM2 â—¼   COLOCALIZATION ✅ 0.93 0.93 mint 17159902 5219425
CCNA1 CDK2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
DNMT1 UHRF2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
RBBP9 RB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 9697699 16189514 21689726
MO4L1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 28514442 17573780 26344197 20332121
TFDP2 E2F3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 7739537 8755520 26186194 28514442
CDK2 RB â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10486249 16314512 9315635 21697511 8943373 15173007 12361598 12190313 12970441 11433299 19225156 16878158 15811853 20871633 10938106 9053846 10499802 10207050 15003538 9029153 9139732 8647086 15828833 16326706 8756624 11306463 16189514 9199321 9258347 9885575 8626527 12676926 17254966 12800980 15241418 14681231 9190208
RB CDK6 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10491434 9885575 10486249 8822197 22094256 16878158 24953629 7629134 14627988 16985050 9199321
HDAC2 SUV91 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 11788710 12711603
TFDP1 E2F1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
TFDP2 E2F2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 7739537 8755520 26186194 28514442 16189514
CCND3 CDK6 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
AHR RB â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10644764 11259609 9712901 18524851
CEBPB RB â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 18628207 11596110 8552662
RB PP1A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 17008050 16189514 12434308 17274640 10889204 8384581
ANDR MDM2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 17974989 28151478 33332287 26196320 26973243 23132866 12145204 21157430 28708672 27903893 29755129 32801300 26411689 29402932 18332867 15640443
HDAC1 SUV91 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 11788710 10873456 12711603
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
LIN9 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
CDK6 CCND3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 16782892 11360184 21516116 8114739 26264872 23602568 14681455 32814053 9716181 16713569 32707033 33854235 27107012 32296183 17517622 15232106 30217970 28514442 25416956 16189514 26186194 29997244
P53 HMGB1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9472015 11748221 23063560 16713569 11106654 16189514
P53 MDM2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21317885 11839577 23201157 21316347 25312347 22975381 17369817 21084285 30005830 23443559 21465263 10980696 17936559 10488081 16845383 21149449 22366412 23483203 29549180 14741215 26673821 11713288 18665269 15058298 29524278 28514442 22510990 25241761 22525275 19106616 22467867 25954860 10889512 16595680 24998844 15848166 28628118 28362432 17116689 33650658 14499615 24980433 10608892 26876197 17438265 22103682 22374672 16055726 7689721 17363365 19411066 12167711 23318437 18566590 31796886 30244831 12944468 23261415 27215386 27826076 11178989 19223463 17301054 9724739 32894144 21075307 29121928 19305137 17318220 20659896 20080206 7686617 11744695 18467333 23246961 23150668 23776465 16215989 9223638 16331255 31968249 17908790 14702041 15094782 11278372 28605833 31647545 24200963 10601022 21454483 27893708 21088494 32516735 16861890 26238070 20705607 21887275 19303885 25609649 12915590 31406141 27282385 25156994 23671280 15358376 23609977 25168242 19071110 22991965 22653443 22920093 7926727 17470788 26908445 27856536 26475964 19857530 11709713 11714701 30532073 19411846 11094089 20173098 17591690 9582019 12552135 20542919 28205554 14704432 15001357 29876924 25417702 23880345 20124408 19033382 22487680 30598450 33061576 22575647 9131587 17159902 31152661 17297477 9271120 25384516 24659749 21261729 12529318 22411991 14671306 22084066 20395212 21986495 29487367 33355139 23802716 23370271 23946421 22083959 32807901 15154850 29670376 27905468 35140242 25283148 22085928 11562347 10640350 19098711 32901886 21726810 25624478 25637791 21584881 16870621 12690203 12612087 15824742 11572869 25464845 26203195 22157679 30454706 28082682 9809062 17302414 19085961 24567357 25362358 17080083 17426254 15242646 22524527 29295817 16751805 11431470 26882543 30097011 18604177 20591651 22948151 24462112 10827196 20479273 31533005 22389628 21170087 20694676 17666403 11597128 33503543 14596917 18332869 10321734 21857681 16579792 16414131 18264029 21071676 30464405 17989425 20234175 10681559 27308622 19816404 30355102 19805293 9824166 25313037 16173922 24926618 16159876 26540344 18541670 32904724 17616658 12842086 26720344 27129163 22266868 27031960 32528731 22737255 15604276 16432196 19188367 1614537 22914926 24842904 15247280 32097779 23252402 17347673 16964247 17310983 22331460 30584071 22032989 24240685 31652301 10435614 24621507 24361594 15308643 32334023 16547496 20639885 17139261 15933712 21478269 15313915 23402884 21750659 11112690 19255450 22124327 25277184 19234109 21965653 27336364 15122315 22916255 22262183 15295102 31092600 25512388 16713569 26001071 27807478 31940492 20588255 20174603 20570896 20708156 27886165 17056014 19081178 29547122 23572512 16905769 15542844 19941302 10561590 28542145 32066565 16212962 10202144 28549433 10734067 21572037 18172499 9363941 15550400 17380154 10892746 14559824 22227409 18316739 33495326 17234751 15280377 31177307 24127580 19160491 17290220 8875929 12381304 16857591 18813780 10347217 21561866 24413661 31066983 20847049 21098709 25103245 8058315 22807444 30832340 21268072 20962272 26350565 30175854 20591429 22444248 32427887 16023600 24667498 11351297 11285227 11223036 18784078 11384992 10562557 19568783 31138778 21925390 11486026 19597489 9450543 31665549 22318540 27106262 24207125 15950904 18223694 23728348 22474335 34362424 22912717 20047188 14612427 14517261 30679555 18815136 18061646 28394340 34408321 18309296 11046142 15144954 12897156 23776060 15210108 27811966 19357310 22391559 16338390 29899406 34040386 26186194 11284721 15908921 23652204 33765973 31626714 17848574 9529249 25739118 30879903 10766163 15013777 22588298 18981217 29755129 30320499 11070080 22301280 27543608 30948704 19590512 15558054 12867035 24488098 27462439 18485870 17268548 22819825 31591476 23826318 21471462 9278461 16866370 22659184 19166840 20660730 29269425 31239268 32198344 25543083 17875722 10196247 15053879 21084564 16107876 16678796 17098746 19656744 30109812 11925449 17525743 16624812 30455251 19153082 28553961 21132010 26578655 32874188 31903119 29997244 19837670 20837658 26883110 21060154 33961781 33579943 20235143 15064742 26556313 22745160 20657550 20484049 16152627 11697899 18234963 24314634 12208736 30320919 11713287 28223335 30252118 10722742 31594538 19483087 22266850 24643130 20959462 33020477 21988832 12426395 19332559 23169665 12620407 23134341 27249653
MK14 ATF2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11566021 16456540 14499342 10085140 16998585 10581258 9596579 18695677 10978313 17170118 26391660 21444723 26987986 16945434 12118074 9207092 9753474 7535770 11279118 10708586 11532856 25098452 9162092 9235954 11259586 12110590 31964530 17380123 12697749 11839738 20213747
CBX5 SUV91 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 25931448 32296183 24981860 12242305 32814053 12711603 20562864 27705803 25416956 16189514 12565857
TF3B TBP â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11809839 7624363 30413534 26496610 16713569 18391023 10921893
CDK6 CCND1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14681455 21654808 17420273 33961781 11739795 17517622 11160398 24855949 15232106 9178893 24953629 33854235 11360184 16713569 19075005 10580009 10022865
HDAC1 DNMT1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22274925 10888886 15870198 21670149 17707923 10615135 26794444 17967891 20613874 12473678 17934516 23708667 27593931
TFDP2 E2F1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 35140242 7739537 8755520 26186194 9368098 9501179 28514442 9704927
RBBP4 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 34518534 11302704 11102443 27705803 17827154 10734134 10220385 9885572 10471499 26344197 21258344 12091390 9150133 16713569 11602581 12920132 20127688 9790534 17643391 11470869 19686092 12943729 9150135 28514442 16189514 27068747 10444591 19703393 11171972 15451426 23752268 20585571 9520398 11118440 31435636
RBBP7 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 17255935 22939629 26496610 11102443 27705803 9885572 10471499 26344197 21258344 12920132 9790534 19686092 9150135 28514442 25885317 10444591 19703393 15451426 26186194 23752268
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CDK4 CCND3 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 8153045 21516116
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
E2F5 TFDP1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
E2F1 TFDP1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
E2F4 TFDP1 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
CCND3 CDK4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCND1 CDK4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 MDM4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF1 TBP â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
JUN CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
CCND3 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17517622 8114739 26186194 27107012 23602568 10477583 16782892 21516116 25416956 29997244 31515488 32814053 15232106 32296183 11360184 16713569 9716181
CCND3 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 11896535 25416956 16985050 34591612 21988832 14597415 17517622 16782892 10342870 21516116 23880157 15232106 16189514 11360184 26496610 25910212 26186194 27107012 10477583 19237555 32296183 14641107 9106657 9508775 31515488 9716181
CCND3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CCND3 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9190208 10498883 9315635 10385618 10778858 9736735 7736585 9425340 11520855
SP1 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15922873 10196209
CCNA1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17660363 15840440 16135794 18590585 7575488 17303408 9736735 15133492 15558010 15123636 9556498 10022926 16213134 11980909 16123593 11739724 15279786
BRCA1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12919958 12024016 17352427
ABL1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 23331499 12110584 20651945 29065514 22352870 16702947 25973395 27626309 21081495 27956626 20841568 14757045 19738896 15212693 28690977
ABL1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19818398 18619508 10637231 20841568 14757045 15302935
ABL1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12415271 21212806 26998525 20841568
ABL1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20651945 29262653 26148237 19075013 20841568 28690977 29348869
ABL1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19563810
SP1 AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9778040 16410262 21569840 20478378
ATF2 RAF1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11274345 12738796 18039929 20506250
ATF2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9990041 10915780 11850817 11410592 11739785 15691880 16405968 10464245 10500157 15314161 10066798
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
BRCA1 E2F1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 E2F1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 E2F1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
CTBP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20818429 21681822 23303449
E2F1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10660629 23285190 18660752 19466541 17106239 20068145 23108140
E2F4 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20133863 21701264 17531812 17001309 20818429 17106239 23108140
SP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15252835 17373631 18377656 19466541
E2F4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9244350 18319725 16713569 12909625
E2F1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9244350 18660752 18319725 11278247 12697828 16713569 12909625
CDK4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9244350 16713569 17334399 20932174
CDK2 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8764100 10373534 10550055 19683496 16713569 26719576 15212693
E2F4 CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 11799066
JUN CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16393119 21135252 8917510 17166846 19622016 11402335 20220142 22853846 17670745 10567390 17496887 19499154 9878062 21474819 17278098 15282324 15467760 15994313 14672732 15574422 22550166 10066798 17637753 20482821 15574764 11745411 11410592 18084253 20037604 12794082 10790372 16860316 24190040 17501623 17477349 19435822 10500157 11432833
E2F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10504464 7929342 22768064 19876926 20220142 9584162 17998543 20655656 8618861 8137237 23078099 23543735 10594784
ID2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19587095 21194482 22835384 12527902 17559421
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
TAF1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15870300 10086334 22711989 12569092 15893730
SP1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 10497251 22911796 19850937 9236224 17617380 9407106 15870300 22415074 10850422 9584162 10908361 22734486 16267018 9637785 19755513 11410592 11024050 15922873 12794082 20435036 22334592
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
HDAC2 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799 15713663
CTBP1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
JUN CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
CCND1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 26203195 17145710 8978686 12036906 23562856 25416956 16985050 23707388 19767775 9837900 17517622 19237565 9372967 25502805 23718855 9228064 7736585 15232106 11360184 20837141 21306487 25910212 25241761 27107012 9150368 18537972 9178893 31217276 8867812 10580009 23007395 11160398 19470470 19075005 9106657 8259215 10908655 8756624 23543736 24855949 7568034 24218572 8662825 31515488 17205132
CCND1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CCND1 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19075005 17517622 9178893 11739795 24855949 15232106 16713569 11360184 10580009 11160398
CCND1 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9190208 10498883 9315635 10385618 10778858 9736735 7736585 9425340 11520855
MYC CDK2 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
MYC CDK2 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
CDK2 MCM7 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 E2F1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12086603 14536078 14988723 15136767 15147722 15175241 15279786 15798197 16713580 16805667 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18469862 18590585 18636226 18995830 19282663 19342888 19622404 19793801 20051983 7575488
E2F4 CDK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 22447046
CDK2 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17601773 22369944 17570479 20818427
CDK2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7575488 18590585 9315635 17303408 17570479 25101673 16213134 17660363 12006580 11420722 15279786
CDK2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8386367 27653698 17081983 19966300 18669648 29896817 17570479 20713526 17558397 15103331 22348395 20445224
CDK2 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21902831 10942602 25751651 25552934 22179841 17570479 10082583 26825227 10764802 9710583
CDK2 UHRF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 33876395 21952639 15178429
CDK2 ID2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 28122577 9029153 14733935 26110849
CDK2 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21565170
MYC CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15208653 12835716 24951594 21384303 14519204 22395148 10688915 17728244 11983916 18414489
MYC CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 11602341 17093053 22094256
CDK4 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9190208 10498883 9315635 10385618 10778858 9736735 7736585 9425340 11520855
CDK4 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CDK4 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21902831 10022835 10601020
MYC CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20682794 22395148 12835716
CDK6 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9190208 10498883 9315635 10385618 10778858 9736735 7736585 9425340 11520855
CDK6 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CEBPB CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9990015 19581927 10603305 15509789 16431920 19663997 15110775 7862113 10854425 17301242 24216764 20179325 15158467 17646392 18622014
MYC CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15681429 17082780 7556187 8076602 20097210 12695333 15867211 19259613
E2F1 MCM7 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15279786 17218262 17303408 17660363 18328430 18590585 7575488
E2F3 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14576826 7958836 12063292
SP1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9054613 12697671 10446910 18440323
E2F1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8208548 2721961 7753559 11705881 24038073 8355712 1549358 1567856 12629508
TFDP2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 26186194 9704927 9368098 8755520 9501179 7739537
E2F1 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 20211142 15133492 22327218 7892279 16360038 9199321 8405995 9704927 8816798 9780002 8657117 9464260 22629304 7739537 27705803 25368385 9501179 8816502 8832394
E2F4 E2F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 21247883 9149906 15718499
TFDP2 E2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8755520 7739537 16189514
E2F2 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20211142 8657117 8755520 16189514 7739537 8832394
E2F3 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8755520 7739537 8657117 8832394
E2F4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24573694 17132729 17699159 11689553 12757710
E2F4 MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 14990995
EID1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11073989 11073990
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
EP300 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10944526 9001254
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
HDAC3 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
MYC ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12447693 12695333 12824180 18437010 18483244 12545167
ID2 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9242638 8380166 21209940 1922066
JUN RAF1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
JUN MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 2167198 19723510 1313772 8120060 8264634 1310896
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
SP1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20130956 20144149 17882273 15647279
KAT2B MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 9659901 10944526 10619020
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
MDM2 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 69.0 1.0 Omnipath 17145710 10218570 17616658 16511560 22266850 12874296 21925390 25825738 21988832 25512388 16227609 22493164 22902369 25659040 18219319 12963717 15604276 18566590 12370303 19838211 26359458 27617579 25809483 34551723 10608892 23028042 22120712 25703327 12860999 32300648 16055726 24813712 17301054 12483531 23671280 17159902 27621617 25105592 20484049 20724842 27215386 10827196 26001071 11606419 23946421 19683495 20705607 24755078 25384516 20473904 12393902
MDM2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15195100 12759344 14507915 16713569 12915590
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
TBP MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20886042 7880838 9797456 15876353 14506152
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
MYOD1 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10082523 1662816 9148896
TBP TAF1 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 7597030 17375202 7680771 9153318 9660973 17884155 18391197 16713569 15870300 29111974 15564746 8858156 31753913 8995708 9858607 9674425 17967894 19240132 9603525 9311784
TAF1 TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16858867 11316804 9699517 15808844