Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HMGA2 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21339738
ATM HMGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21339738
TP53 ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9925639 10435622
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
RASSF1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12024041
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
HMGA2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20074583 18957199
CSNK2A1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20711232
PRKDC H1-1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18250087
SMARCA4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11950834 33476981
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
YBX1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12835324 16963428
TP53 ZSCAN25 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
TP53 YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18504427 22417301
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
RPS27A USP7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
USP7 RPS27A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 26235645
RB1 HDAC1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TCF3 PVR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2960975 2157873
HMGA2 E4F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14645522
TCF3 ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15826912 12748286
ANP32A E4F1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17557114 5225803
E4F1 ANP32A â—¼   COLOCALIZATION 2.0 0.8 intact 17557114 5225803
LNX1 E4F1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8201084 21666599
E4F1 CTNND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14645522 10869426
SMAD9 E4F1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
E4F1 LNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8201084 21666599
SMAD9 SF3B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PTCD3 LNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MRPS7 RPS8 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
RB HMGA2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16766265
PVR ATR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 DDX21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DDX21 DKC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25470060
DDX21 RL19 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 33961781
E4F1 LARP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PARP1 ZEB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 34462429
E4F1 C1QBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
C1QBP RT07 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 22904065
C1QBP RT22 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 22904065
C1QBP RT09 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 22904065
C1QBP RT02 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 22904065
C1QBP PTCD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 22904065
C1QBP RT29 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 22904065
C1QBP RT05 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 22904065
C1QBP RT23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 22904065
E4F1 ABT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LNX1 LNX2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11922143 22889411
ESR1 MOV10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
FBLN3 E4F1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VWCE E4F1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RL36L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RL26 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 ZN770 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 ZBT24 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 ZBT11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT22 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT09 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RS27A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 UBE2O â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 PTCD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RPF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT31 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 LTBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 ZNF70 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 H11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 ZN579 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RS8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 DBPA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT33 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT24 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 ZC3H8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT35 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 ZN574 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT02 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 HIC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 ZN771 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RS16 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 ZN498 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RL19 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 SURF6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 CSK21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT05 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 GZF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RL26L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT29 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT18C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 YBOX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 LIN41 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 RT07 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RS8 SF3B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
RPF1 RS16 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RPF1 RL26L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RPF1 ZBT11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN574 UBE2O â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RT05 PTCD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
PTCD3 RT29 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
PTCD3 RT09 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
PTCD3 RT35 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
YBOX1 RS8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 22118625
YBOX1 RT22 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 22118625
YBOX1 RT07 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 22118625
YBOX1 MOV10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25497084 23986595
YBOX1 RT31 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 22118625
YBOX1 RT05 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 22118625
P53 MOV10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32807901 25609649
P53 RT22 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22653443 23443559
P53 RS27A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22653443 21561866
RL26L RS16 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
RL19 RS27A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 33961781
RT11 RT07 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RT35 RT07 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
ZN574 RT09 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RT09 RT22 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
RS8 RT31 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
RS8 ZC3H8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
RS8 RT35 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RS8 ZBT24 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RT22 RT23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
RT02 RT22 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
RT11 RT23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RT11 RT33 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RT11 RT35 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RT24 RT11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VWCE LTBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN574 LTBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MRPS33 MRPS9 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
MRPS24 MRPS9 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
TP53 YBX1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
MRPS7 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPS18C PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPS24 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPS33 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
LNX1 RPS27A â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
MRPS18C MRPS23 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
LARP7 DDX21 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26725010 29845934 33961781 25470060
H11 LARP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 29845934
ZC3H8 LARP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26725010 33961781 26186194 29845934
RS8 LARP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26725010 33961781 26186194 29845934
RS8 DKC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
AN32A E4F1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17557114
NSA2 RL26L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT11 PTCD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT02 PTCD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26186194 26344197 24981860
RS8 PTCD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PTCD3 RT23 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
RT29 RT23 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
RT29 RT02 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
RT29 RT11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
RT29 RT09 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
RL19 RS16 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197
RS16 RS8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22863883 33961781 22939629 26344197
H11 SURF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT02 RT07 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT07 RT09 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197
RS8 RT07 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RS8 RT09 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT35 RT09 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
RT11 RT09 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT05 RT09 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT09 RT23 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
RS8 RT05 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RS8 RT11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RS8 ZN498 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
H11 MOV10 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT35 RT23 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
RT05 RT23 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT02 RT31 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
RT02 RT11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT02 RT35 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
RT05 RT11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT31 RT11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT11 RT18C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
H11 ZN574 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
H11 RL36L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
H11 ZN498 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
H11 ZC3H8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
H11 ZN771 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
H11 LIN41 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
H11 ZNF70 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT31 RT24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
RT31 RT33 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT31 RT05 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT31 RT18C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT05 RT18C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RT05 RT33 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ZC3H8 RL26L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CSNK2A1 HDAC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MRPS18C MRPS22 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
MRPS18C MRPS24 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
MRPS18C MRPS33 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
PRKDC PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16794079 9398855 21575865 20085707
RT29 ESR1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10903152 21182203
ESR1 RT22 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
ESR1 RT31 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
ESR1 PTCD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
ESR1 RT02 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
ESR1 RT35 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
E4F1 FHL2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 16652157
RB P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20871633 8083962
SMARCA4 TP53 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
LARP7 YBX1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
DAP3 MRPS33 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DAP3 MRPS24 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MRPS23 MRPS7 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MRPS23 MRPS24 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MRPS23 MRPS33 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MRPS24 MRPS7 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MRPS33 MRPS7 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MRPS22 MRPS7 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MRPS22 MRPS24 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MRPS2 MRPS24 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MRPS24 MRPS33 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MRPS22 MRPS33 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
C1QBP YBX1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
LARP7 CSK21 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22113938 29845934
P53 CCNA2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16713569 10884347
CCND1 CDKN2A â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
ATM PRKDC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10608806 10464290
PARP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 16204234 20596014 19470756
ESR1 FHL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15666801 31527615
CCND1 ESR1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
E4F1 TP53 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
C1QBP DDX21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 32877691 28565870
YBOX1 DDX21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25497084 33961781 23986595
YBOX1 LARP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23986595 25497084 26725010 33961781 29845934
HDAC1 E4F1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12730668 21666599
ESR1 RL36L â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21182205 21182203 31527615
RT31 PTCD3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 26186194 26344197
YBOX1 DBPA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25497084 33961781 23986595
YBOX1 RT29 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25497084 33961781 22118625
RT31 RT29 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 26186194 26344197
RT05 RT29 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26186194 26344197
RS8 RL26 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 26344197
RT31 RT07 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 26344197
RT31 RT09 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 26186194 26344197
RL19 RS8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 26344197
RS8 RL26L â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 26344197
RT31 RT23 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 26186194 26344197
RT02 RT23 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 26186194 26344197
RT31 RT35 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 26186194 26344197
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ATR TP53 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
LARP7 ZC3H8 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RB1 SMARCA4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PRKDC P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11551930 10747897 25362358 9679063 11709713 9765199 10601022 11883897 19918261 12756247 10713094 11751391 8940078 10951572 10673501 10608806 9744860 10470151 16713569 9363941
RL19 RL26 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
RL26 RS16 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21376236 26344197
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
PRKDC TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CCNA2 RB1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
P53 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19303885 25241761 11313951 10777477 16697957 10521394 19011633 26539911 20075864 12426395 22266186 16107876 17827154 11099047 16959611 20633551 14976551 18765668 32494626
P53 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 26556313 10766163 17545634 21761334
E4F1 RB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 10869426
YBOX1 PTCD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25497084 33961781 22118625 23986595
CSK21 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15358769 25241761 23443559 11709713 10951572 11883897 10747897 12628923 10348343 12393879 24725084 22975381 10884347
RT02 RT05 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
CDKN2A TP53 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ATM P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28654064 11551930 14744854 27559048 11875057 15790808 11459832 11709713 9765199 23525106 21383020 25086746 10864201 23907539 15064416 10713094 24469230 15159397 20010693 10673501 19965871 17157788 9843217 15632067 23890999 10608806 10744722 16858402 16713569 17409407 15713674 30252118
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
ATR P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16293623 15159397 11551930 11709713 9765199 10951572 15775976 10747897 11883897 10673501 20798688 15082766 10608806 10435622 11459832
RB CCND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15485920 9003781 8867812 9823309 8662825 9139732 11593423 10486249 11126356 12676926 15681588 21242975 31217276 10491434 9190208 8490963 8647086 8449399 21654808 9178893
CCND1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16061635 9039267 11073968
YBX3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16508013 20133805 19730435
P53 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 9312059 23169665 15044383 12898523 14627987 9565608 32807901
TP53 FHL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18615633 11062252 22796152
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
HDAC1 RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10490602 16189514 15003538 11909966 15485920 10888886 11158299 11896613 11583987 10228159 9988677 10778858 11839806 22615382 19081374 12466959 26264872 9491888 10615135 16766265 15044952 17827154 22366686 12473678 10499802 23752268 10891495 9468140 11684023 10958676 21900881 29997244 9724731 10779361 9468139
E4F1 ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1387083 2965007 2169022
ESR1 APRT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
E4F1 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 17110336 12446718 10644996 16652157
P53 YBOX1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 23443559 21344396 11175333 11973333 25144556 15136035 32807901
RT29 RT35 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 24981860 26186194 30021884 26344197
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
RPL26L1 RPS16 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
HDAC1 RB1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
RPL26L1 RPS8 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
MRPS18C MRPS7 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
SURF6 CSK21 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22113938 27705803
RT02 RT09 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 24981860 26186194 22939629 26344197
MRPS22 MRPS9 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
MRPS22 MRPS31 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
MRPS22 PTCD3 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
MRPS9 PTCD3 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
RPS27A USP7 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
CCND1 RB1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
MRPS22 MRPS5 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
MRPS24 MRPS5 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
MRPS2 MRPS33 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
RB1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 6550000 10779361
MRPS2 MRPS22 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
MRPS23 MRPS9 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
DAP3 MRPS7 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
RPL26 RPS27A â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
DAP3 MRPS18C â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
MRPS18C MRPS9 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
DAP3 MRPS22 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
MRPS33 MRPS5 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
MRPS24 MRPS31 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
MRPS22 MRPS23 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
CSK21 HDAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32707033 23752268 22113938 11327722 11602581 17827154
MRPS23 MRPS5 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
MRPS18C MRPS31 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
ATM ATR â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MRPS2 MRPS31 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MRPS31 MRPS5 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
MRPS31 MRPS33 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
YBOX1 C1QBP â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22118625 21653829 23986595 25497084 33961781 26344197
DAP3 PTCD3 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
MRPS23 PTCD3 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
DAP3 MRPS23 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MRPS7 MRPS9 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
MRPS31 MRPS9 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MRPS31 PTCD3 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MRPS2 PTCD3 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MRPS5 PTCD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
MRPS23 MRPS31 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MRPS2 MRPS23 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DAP3 MRPS31 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
MRPS31 MRPS7 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
RPL26 RPS3A â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPS27A TP53 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
MRPS18C MRPS2 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPL19 RPL26 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPL26 RPS16 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
MRPS5 MRPS7 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
MRPS2 MRPS7 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MRPS18C MRPS5 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL26 RPS8 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMARCA4 SMARCD1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPL19 RPS27A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPS16 RPS27A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPS27A RPS3A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPS27A RPS8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DAP3 MRPS9 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DAP3 MRPS5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
DAP3 MRPS2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MRPS2 MRPS9 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MRPS5 MRPS9 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MRPS2 MRPS5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL19 RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL19 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL19 RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS16 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS16 RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS3A RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATM PARP1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATR ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15510216 10608806 17478428 17124492
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
ATM RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 31175105 22438769 19962312 27322327 10608806 22389451
ATR PARP1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12186630 22592045 22057367 24500207 18077418 16908529 15507430 29309644
ATR TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17145710 22778941 24395704 28468838 12401524 15159397 24877058 15254178 9733515 11483158 15806145 19056039 11875057 15865930 11551930 11883897 19923893 12548019 18697815 29170437 16293623 19010925 11709713 10446957 9363941 21748595 17272272 22797063 12242661 10196661 22084686 10747897 10608806 10673501 12091386 17118344 23892398 9765199 15489221 24037342 15140942 10435622 17241873 10597277 10801407 11711532 17174997 21593792 25201202 9843217 10606744 15024084 15226429 15922368 21415014 21480565 15585169 24947324 9925639 23380594 9733514 11865061 19625493 16390936 10951572 10570149 23311997 12111733 26144601
RB1 CCND1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
ESR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11477579 12554765 12808053 17166846 22892083 21505052 18414489 9832502 23864650 22396492 22266855 11358796 23891847 22948256 11986316 15282324 15496458 22521644 14764652 15178330 23108396 11410592 15026472 17998543 17681750 18245487 20821348 16860316 11844790 19858209 12929585 15808510 18997820 15217513 16809759 10500157 16980581 17914104
TP53 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 24189068 8702807 10669755 22270849 12808109 17942917 19086036 20731879 16061648 20554748 24460719 11798189 10082575 15205322 18769160 19800042
TCF3 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
ESR1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8649771 11073968 16061635 9039267
CCND1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 10498883 9315635 17303408 16236519 11520855 15279786 9190208 7575488 10385618 9736735 8490963 26225123 19237565 7736585 19075565 18590585 27507850 26121043 20068082 9425340 18786381 17660363 10778858 9380698 27430527
TP53 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 16103197 22467867 18555006 8631601 11402335 19649205 22020338 21164364 17265068 16764954 15775976 22056554 18275833 21483786 10348346 19216023 12384561 12091906 19901969 11360201 15205322 11818069 21892281 10980602 11739748 11559812 24672805 10097151 17907153 19244234 15361884 10652576 9436028 21447739 20569441 21555589 21637567 10816133 9774662 19240179
TCF3 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15138269 20194619
CDKN2A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15856024 15989956 9724636 19960022 12740913 17158541 12640129 19590512
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
PARP1 H1-1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18250087 18851700 18927583
PRKDC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 15355354 19398950 15254178 9372954 11483158 7862459 16713569 11875057 11551930 11883897 12548019 25168287 8502477 11709713 10446957 28145533 22726545 24886358 16552184 12242661 17570479 10196661 10747897 9885574 10673501 12091386 22355272 9765199 15489221 9561848 10801407 22504299 22444248 15177184 11042698 10358069 10470151 10606744 9744860 16397295 12959929 12064478 27130668 10951572 12111733 25937999 15381073 28102346 9363941 19918261
TP53 RASSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23779024 23038753 21364923
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
TP53 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16931621 8270002 9275177 19671680 16571800 8641461 9360984 21952947
TP53 PVR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10644996 10435089 9037031 9094626
TP53 ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20935676 9649502 10514438 17209038 9288775 22243239 9525640 2936901 7823921 10435630
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
E4F1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10644996 16652157 12446718 16713569 17110336
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
CCNA2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14640983 10884347 16713569
HMGA2 ZEB1 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12743038 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 19839049 20519943 20731704 21199805 21224848 21317430 21614932 21883379 22006115 22406545 225147423 22945800 9389648
HMGA2 ZEB1 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12743038 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 19839049 20519943 20731704 21199805 21224848 21317430 21614932 21883379 22006115 22406545 225147423 22945800 9389648
HMGA2 ZEB1 â—¼   UP_REGULATES ✅ + 36.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12743038 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 19839049 20519943 20731704 21199805 21224848 21317430 21614932 21883379 22006115 22406545 225147423 22945800 9389648
ZEB1 TCF3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
CSNK2A1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17287340 19413330 22113938 18669648
E4F1 PVR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10644996 9418893 16112766 2956091 1831536 2545525 2169022 10373523 1387083 12730668 2960975 9121437
HMGA2 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17324944 21566082 17005673 14645522
E4F1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11283272 14645522 15805267
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153