Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EP300 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20488183
GSK3B YBX1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16198352 5217974
GSK3B PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6673085 7514173
YBX1 CUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218767 16797541
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
APEX1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15634666 20856196
ALYREF AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18562279 0802533105
AKT1 KHSRP â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17177604 19198587
JUN AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 11192249
SIRT1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21775285
AKT1 LARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28650797
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
TRAF6 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0906941106 19955404
ARRB2 MDM2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5214648 11588219
BCAS2 CASC3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
BCAS2 RNF113A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
IRF1 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10751398 23271966
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
SF3A2 BUB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
G3BP1 CAPRIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
G3BP1 CAPRIN1 â—¼   COLOCALIZATION 2.0 0.8 intact 6665011 18005740
CAPRIN1 G3BP1 â—¼   COLOCALIZATION ✅ 0.8 0.8 mint 18005740 6665011
UPF1 CASC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19478851 1000120
CASC3 PLRG1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CASC3 PRPF19 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CASC3 SNRNP200 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CASC3 SRRM2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CASC3 SNRPB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
JUN CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18196534 17922191
SIRT1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22249256 21640770
TFAP2A CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10652362
COPS5 IFIT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17050680 0607830103
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
EIF4B DDX3X â—¼   COLOCALIZATION 2.0 0.8 intact 8407815 22872150
DDX3X EIF4A1 â—¼   COLOCALIZATION 2.0 0.8 intact 8407815 22872150
JUN DUSP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20702711 19585511
MYC DUSP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14519204
EP300 DUSP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20626350 18504304
EEF1G HNRNPH3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EGFR PTPN1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 9355745 6671413
MYC EIF4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18593934
EIF4A3 EIF4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EIF4B RPS6KA1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5218723 16763566
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
ESR1 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6673088 7539106
ESR1 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14605097
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
KRR1 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EWSR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8164678 11423975
FN1 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16005629 16115959
SF3A2 FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
MYC HERC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
U2AF2 HNRNPA0 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPUL1 PRPF40A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PA2G4 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IFIT3 IFIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
YBX1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12446674 8163940
NPM1 IL7R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RNF113A ILF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SF3A2 ILF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
ITGA4 JAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12070135 17525755
JUN UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JUN SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
JUN PDGFB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10506481 9488709
RALY KHDRBS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
U2AF2 KHDRBS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
KHDRBS1 U2AF2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
KRT8 NAA10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC LIN28B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23318446 19211792
LRRK2 POU5F1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
MAPK1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK1 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
RPS6KA1 MAPK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MYCN MCM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17826980
RBBP6 MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0701916104 17470788
MECP2 PTPN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26214522
MRPL40 NDUFAB1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL48 NDUFAB1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MYC UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC NOP56 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC YBX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
MYC PGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18809243
SF3A2 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
NCBP2 NCBP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SF3A2 NCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
PA2G4 RPS11 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SF3A2 PRPF19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
UBQLN1 PRPF40A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RPS11 XBP1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SNRPB SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SRRM2 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
YBX1 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SNRNP200 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
U2AF2 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3B1 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SYNCRIP SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
ATXN2L G3BP1 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
NPM1 PA2G4 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
NCBP2 PRPF40A â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
ALYREF NCBP1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
BCAS2 SRRM2 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
APEX1 EP300 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
TRAF6 GSK3B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 30711629 30806153 31594754 31754475
MDM2 AKT1 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
AKT1 MDM2 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
IRF1 EP300 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 14662860 23670564 10438822 15509808
IRF1 MDM2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 23134341 24583282 24721577 27795392
CASP8 TRAF6 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
H2AX CTCF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CUL1 STAU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30948266 21145461
VCAM1 ACTN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
JUN APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 34079125
EGFR APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24780295 28065597
ESR1 APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
APEX1 NOP56 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28986522 34079125
EGFR APOB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24189400 28065597
MOV10 BMI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 20543829
BMI1 CASC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 FUS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 RALY â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 NCBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 RBM14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 NOL6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 NCBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 STAU2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 ILF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 G3BP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 G3BP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 STAU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
VCAM1 BUB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
PDGFB C1QBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRY1 C1QBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25756610 23133559
E4F1 C1QBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
C1QBP PTCD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 22904065
ESR1 CAND1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
CAND1 STAU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30948266 21145461
U2AF2 CASC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CASC3 STAU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15680326 12843282
MOV10 CDC20 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22658674 29395067
CFTR STAU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CRY1 ILF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25756610 23133559
ZCRB1 CTCF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MDM2 CUL4B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28225217 22032989
CUL4B DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34026424 21145461
CUL4B RBM14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28225217 21145461
G3BP1 DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26777405 29395067
ESR1 DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20308691 19805454 21182205 20348541
VCAM1 DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
NFX1 DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29395067 31059266
TRAF6 DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27507811 17353931
DDX41 SRRM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 25920683
RRS1 DHX30 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOX2 DHX30 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 21280222
DHX30 ILF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22939629
E4F1 UBE2O â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
E4F1 PTCD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
E4F1 GZF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HDAC6 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15102857 19344692 12718889 22778253 23133622
ESR1 MOV10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
ESR1 RRS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
ESR1 RBBP6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20184719 31527615
VCAM1 FUS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
FUS PGK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25192599 26344197
VCAM1 G3BP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HDAC6 G3BP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32082291 18079183 21532619
G3BP1 LARP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26777405 29395067
ZCRB1 GLYR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VCAM1 ILF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MCM5 ILF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25963833 20808282
ILF3 RRS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 29395067
ILF3 STAU2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 29395067
ILF3 STRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 29395067
MYC JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
ZCRB1 KRR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RRS1 KRR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SURF2 LARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
ZCRB1 LARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK2 PTCD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
VCAM1 MCM5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
NEDD8 MCM5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18274552 18247557
PDGFB MDM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MECP2 RPF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STAU1 MOV10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29395067 23125841
MOV10 STAU2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22658674 29395067
SF3B1 MYC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20936779 29467282
MYC RFC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYC NOP58 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC U2AF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
STAU1 NOP56 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29395067 30948266
PDGFB RPF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PDGFB PTCD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SF3A2 PLRG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17332742 26344197
VCAM1 RALY â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
STRBP RALY â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STAU1 RALY â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VCAM1 RBM14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
STAU1 RPF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29395067 30948266
RRS1 ZCRB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RRS1 SF3B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZCRB1 SF3B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STRBP STAU2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZCRB1 STAU2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DAP3 MRPL48 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
MRPL13 MRPL48 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL13 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL40 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL43 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL43 MRPL48 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL48 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL48 MRPS5 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
NOL6 RPS11 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
EIF4A1 RPS11 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
BCAS2 HNRNPH3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
AKT1 GSK3B â—¼   DOWN_REGULATES ✅ - 0.82 0.82 Signor 15829723
AKT1 GSK3B â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 23552696
FUS SYNCRIP â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
SURF2 H2AX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CRY1 CUL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25756610 17463251 34237211 28514442
TRAF6 BIRC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20097753 24464131 23524849 29545793
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
ESR1 DHX30 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 31527615 21182205
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
ESR1 SART3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 23403292 31527615
ESR1 MCM5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 23403292 31527615 19805454
ESR1 SRPK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 31527615 21182205
FUS RALY â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29884807 30354839
STAU1 ILF3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 29395067 23125841 15303970
STAU1 KRR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 29395067 23125841
MCM5 SF3B1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25963833 24981860 26344197
SURF2 MDM2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MOV10 NFX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22658674 29395067 31059266
NCBP1 STAU1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15680326 30948266
SRPK2 RBBP6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 23602568 32460013
SURF2 RRS1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SURF2 ZCRB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BCAS2 EIF4A3 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
MRPS5 PTCD3 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CASP8 CUL3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CFTR USP10 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EP300 IRF1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MDM2 NPM1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RBM14 SF3A2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
BCAS2 SF3B1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
DDX3X FUS â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
DUSP1 MAPK1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CBX6 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
EP300 ILF3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33742100 20808282
ESR1 PA2G4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 PTCD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
LRRK2 LARP4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31046837 29513927
ATXN2L G3BP2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
BIRC3 TRAF6 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
EIF4A3 SNRNP200 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MRPL40 MRPL48 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EIF4A3 PLRG1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
RNF113A SRRM2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
PA2G4 SERBP1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
BCAS2 MAGOH â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
C1QBP YBX1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
MAGOH PLRG1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
MAGOH SNRNP200 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
MAGOH PRPF19 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
MAGOH SRRM2 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
ACTN4 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21078666
TRAF6 CASP8 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16436380 27810922 16920630 30979779
EP300 MCM5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33742100 30110629 20808282
EIF4A3 SNRPB â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
MAGOH SNRPB â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
FBL NOP56 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
KRR1 RPS11 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
CASC3 EIF4A3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
CDC20 FZR1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
MDM2 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24804778 20708156
CUL3 PLRG1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26949739 21145461
NEDD8 CUL4B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 10597293 18274552 21145461 16503656 23201271 31973889 16620772
NOP56 GLYR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 26344197
SOX2 SRP72 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
SRPK2 SRRM2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 23602568 32707033 26167880
RNF113A SNRPB â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
JUN MAPK1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CBX6 MOV10 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21282530 20543829
EGFR ARRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
G3BP2 G3BP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26777405 24981860 29395067 26186194 28514442
IFIT2 IFIT1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 21642987
MYC SMC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 17353931
RRS1 STAU1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 29395067 30948266
RRS1 U2AF2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22939629
STAU1 STAU2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 29395067
SYNCRIP YBX1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
G3BP1 G3BP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
NOP58 RPS11 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
BCAS2 SNRPB â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PLRG1 RNF113A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RNF113A SF3B1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RNF113A SF3A2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RPS11 TSR1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
IFIT2 IFIT3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
FBL NOP58 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
H2AX KRR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
CAPRIN1 G3BP1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
RBM14 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11443112 16713569 33742100
FUS EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33742100 30110629 18509338
NOP56 KRR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 34079125
MDM2 RBBP6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24124579 17470788 29369481
U2AF2 SF3B1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27720643 22939629 26641092 16713569 28514442
SRPK2 SREK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23602568 32707033
ARRB2 MDM2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
FBL RPS11 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SF3B1 SRRM2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MYC GSK3B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16247449 20713710 19131971 21150319 31638140 29467282 11877389 33541412 14563837 8247524
EGFR ACTN4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 26320552 25402006 24658140
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
CASC3 UPF1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MDM2 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12897156 17545634 10766163 11178989 16713569 31012223
JUN ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17317669 16713569 23747343 11477071
ILF3 FUS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29884807 27460707 11438536 16713569
MYC NOP56 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 17314511 29467282 17353931
NOP56 RRS1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 22939629 34079125
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
EGFR PTPN1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
BMI1 CBX6 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
AKT1 MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
EIF4A3 SRRM2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
KHSRP GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B EEF1G â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
GSK3B MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055726 18505846
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
YBX1 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24832798 24446247 19261809
AKT1 EEF1G â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
POU5F1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23041284 20683952
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
TRAF6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34938598 19713527
EP300 APEX1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20856196 19934257 14633989 30110629 20808282
MYCN APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
SIRT1 APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19934257
MDM2 ARRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18544533 21389118 21081496 33649538 32828283 17984062 32450252 12538596 21988832 15878855 26545496 12488444 21466165 11588219
CUL3 CAND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21145461 21249194 22013077 16449638 22405651 26286618 12609982
COPS5 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18926707 17879958
CTCF LRRC59 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
CTCF HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
HDLBP CTCF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31917284 24725430
MYC CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10229837 11145693
PTPN1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 6671413 9355745
MYCN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
PTPN1 EGFR â—¼   PHOSPHORYLATION ✅ 0.9 0.9 mint 6671413 9355745
PTPN1 EGFR â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 6732094 9050838
EGFR PTPN1 â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 25796184
MYC EIF4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC EIF4B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 IRF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15509808 10438822
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
MECP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21655924 23242655 15870696
TFAP2A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10497269 19458056 9850080
ESR1 TYMS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10875244
FN1 ITGA4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 20644254 22067905 24202395
HLA-C IFNG â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
JUN VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9468519 16271621
MAPK13 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11788583
MAPK1 RPS6KA3 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MAPK1 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23024368
MYCN MCM5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17826980
TSG101 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11172000 17060450
NDN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26384308 24349431
TFAP2A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9632747 8276360 7555706
MYC SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12080043 18414489
MYC SNRPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYCN OASL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
RBBP6 YBX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18851979
RRS1 RPF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28514442 26344197 30021884
U2AF2 SRPK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 32296183 9472028 16713569 28514442 23602568 16189514 32707033
SF3A2 U2AF2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
SNRPB SRRM2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
MRPL13 NDUFAB1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
IFIT1 IFIT3 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
EIF4A3 PRPF19 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
SRPK2 U2AF2 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
GTPBP4 RRS1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
SF3B1 U2AF2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
BUB3 CDC20 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
BCAS2 SF3A2 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
NOP56 RPS11 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
NOP56 NOP58 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
NOP56 NOL6 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 26496610 26344197
NOP56 TSR1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 26496610 34079125
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
AKT1 GSK3B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
KRR1 NOL6 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MRPL1 MRPL13 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
NOL6 NOP56 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
U2AF2 C1QBP â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 28514442 32877691
FBL KRR1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
ABCF2 EEF1G â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EEF1G SNRNP200 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PLRG1 SRRM2 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
SF3B1 SNRPB â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
NCAPD3 SMC2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
SF3A2 SRRM2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
PRPF19 U2AF2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PLRG1 SNRPB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PRPF19 SRRM2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PRPF19 RNF113A â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PRPF19 SNRPB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS11 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
NEDD8 CUL2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 23401859 24654937 18274552 10597293 10318914 21145461 31444342 18826954 16503656 23201271 18247557 19617556 18173839 17132228 10585493 16620772
KRR1 NOP58 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
SNRNP200 SRRM2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
DAP3 PTCD3 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21765416 16177058 18723677 18627766 17438373 32726803 24654937 11027288 18274552 10772955 16503656 24076655 18247557 22405651 17318178 10713156 19713960 10318914 21102408 23267066 23201271 22959436 17206147 16620772 18805092 10597293 21119685 21145461 18826954 19245792 19617556 12565873 18264111 24949976 22474075
DAP3 MRPL40 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
NCBP2 NCBP1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11545740 24981860 9933612 22939629 26496610 26382858 26264872 31448526 26344197 17190602 32814053 12374755 29997244 29101316 31467278 22365833 29395067 19668212 16189514 7478990 23665581 12434151
MRPL13 MRPL40 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
MRPL40 MRPS5 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
KRR1 NOP56 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
IFIT1 IFIT3 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
RNF113A SNRNP200 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BCAS2 SNRNP200 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
NOL6 NOP58 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
GTPBP4 RPF2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
FBL NOL6 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
G3BP2 USP10 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
MRPS5 PTCD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
MRPL40 MRPL43 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
G3BP1 USP10 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
MAPK1 RPS6KA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PLRG1 SF3B1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
SF3A2 SNRNP200 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
SNRNP200 SNRPB â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
DAP3 MRPL13 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
DAP3 MRPL43 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MRPL13 MRPS5 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MRPL13 MRPL43 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MRPL43 MRPS5 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
PLRG1 SNRNP200 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
BCAS2 PLRG1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PRPF19 SF3B1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPF2 RRS1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EIF4A3 MAGOH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
FBL NOP58 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
FBL NOP56 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NOP56 NOP58 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PLRG1 SF3A2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
POU5F1 SOX2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SF3A2 SF3B1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EIF4A3 UPF1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SF3A2 SNRPB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CASC3 MAGOH â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
NCBP1 NCBP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SF3B1 SNRNP200 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
BCAS2 PRPF19 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
DAP3 MRPS5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PLRG1 PRPF19 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PRPF19 SNRNP200 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PRPF19 SF3A2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RNF8 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19772495 7575488 18590585 17303408 18001824 18678890 18583988 18001825 18678709 12607003 9407949 17660363 18006705 15279786 15459660
RPS6KA1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11584304 11583116 23331499 8250835 7980435 8524413 24931005 19346560 12054501 16039586 12147701 11035810 22615844 16543730
AKT1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 99.0 1.0 Omnipath 17428466 15207235 17145710 12052830 10729337 8250835 11756412 11923280 16914735 17623045 16697215 8524413 12054501 20398329 18372248 21506126 20028971 12040186 15808505 16543730 20138985 23331499 21303971 16009706 10385618 20214616 23180781 9373175 16039586 15829723 18988627 16282323 11577096 11035810 18669648 18216173 15169778 12851486 16123141 11882383 23109003 9065430 18691976 22094462 10949026 22710759 11715018 12459251 18636226 17192257 11254732 11278246 20858269 9812896 9582355 15023346 17680028 19369195 7945242 12900420 23552696 18387957 10722653 20832730 18570873 12147701 18505846 17052453 17693255 18218901
MAPK1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16039586 28646232 18451303
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
GSK3B MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 73.0 1.0 Omnipath 17081983 18463697 21646472 30037819 26751215 25647305 2663470 20080742 19797085 30003124 16855632 12040186 18679417 11018017 23331499 29229669 16611981 21071413 24265759 20068231 10671551 16039586 17570479 16023596 29258530 12615961 18669648 21113395 22461507 19131971 8247524 16247449 20604938 19575820 15150404 22481935 23668310 19651622 17444818 23964270 20537194 22893788 27684546 24662831 25333250 20399964 11877389 14563837 18408012 17052453 18455992 15212693 16371461 11274345
GSK3B JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 23331499 1846781 25979842 25241761 20537194 21278055 21397588 17482134 1516134 8384355 17570479 16023596 17215518 30086763 92065884 24632621
GSK3B CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16944320 11348595 11967263 14663202 8524413 20080742 19797085 12040186 16611981 10671551 16039586 12615961 15465828 17928543 24063632 10671552 15020233 19575820 17444818 20537194 17052453 9832503 18455992 16371461 11274345
NPM1 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22955283 31434245 16009132 12748172
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
MAPK1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
JUN ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17283040 10369069 17452336 18213731 12907627 14612525 23678002
AKT1 MDM2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
AKT1 SRPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19592491
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
AKT1 ALYREF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18562279
AKT1 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17081983 18691976 11579209 16189514 10480872
AKT1 KHSRP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17177604 19198587
AKT1 ILF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20870937 18097023
AKT1 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23041284 24497960
AKT1 EIF4B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18836482 17570479 25749412
AKT1 YBX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17081983 32028981 33911076 26318844 33151228 20844753 27591085 17704806 21423216 19036157 31906126 15806160 24335958 34272387 33379356 19651622 31387591 16354698 19664994
AKT1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 11756412 11923280 20856200 20452955 20398329 18332867 19664995 10217147 11154281 19216069 20214616 11463845 19166854 15527798 9829964 17570479 16680151 17646672 12145204 15169778 15140942 25241761 11715018 25209720 17680028 21930127 11504915 29311840 15574337 23397142
MAPK1 APBB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14697653
MYC APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14519204 11983916 12695333 11085504
EP300 APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14633989 20856196 20711647
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
CDC20 BUB3 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10477750 11402067 11535616 12640463 15024386 15279786 15592459 17303408 17376779 17498870 17660363 18022367 18590585 19154723 19182530 19503101 21270334 23197039 7575488 8824189 9790499
CDC20 BUB3 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10477750 11402067 11535616 12640463 15024386 15279786 15592459 17303408 17376779 17498870 17660363 18022367 18590585 19154723 19182530 19503101 21270334 23197039 7575488 8824189 9790499
CAPRIN1 G3BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17210633 34799561 18005740
IRF1 CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17036321 14993214 22427665 23255602
MYC CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15367674 12695333
MAPK1 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 24342355 17290218
IRF1 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14993214 19129219
CDH1 IFNG â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
TFAP2A CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9328434 17224907 12391156 10523846 9632747 21377456 12903198
MYC CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9632747 19176757 23364919 10523846
ESR1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12726856 14500345 17893710 19383788 19593637 20101232
CDH1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17548604 10969083 15662113 31980649 14681060 25241761 24189400 25468996 24658140 25402006
CTCF CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19129223 22422629
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
COPS5 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25609649 20093369 18926707 10766246 16713569 8837781
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
DUSP1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 18519678 9925641 11278799 9430728 8389479 23331499 7761091 21071413 8626452 16286470 9922370 7535768 10617468 8221888 7939666
JUN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16170369 23455325 15923621 16423552 10803405 18604200
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
TFAP2A EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16449191 8621697 14522076
YBX1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19036157 17595327 24211838 19648825 17875215 16651443
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
TGFB1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20953304 32103204 19132220 28943431
EGFR PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 25796184 31980649 8621392 12573287 18253097 11106648 11506178 24658140 7540771 9050838 9355745 15982634 25402006 10889023 7693694 8999839
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
RPS6KA1 EIF4B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15187187 21233202 17924679 16286006 16083285 15071500 17664694 16763566 19114553 19413330 15239952
IFNG EP300 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 MACROD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17893710 18206366 19403568 15691879
RPS6KA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10949034 15528270 19925796 15461668 25336146 11139588 12118371 30034315 15059947 16076840 7491495 12093745 11432835 10411321 11507039 9528769 7838153
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
RPS6KA3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11139588 23936765 17570479 19925796 11432835 11507039 19112174 9528769 7838153
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 XBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12954762 12047351 14605097
FBXO33 YBX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16797541
JUN FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24342046 21479385 11052809 9756884 23744703 10325245 11896591 10421838
MYC FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14519204 11896591 8376401 10421838
FN1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9117345 9842903 19738201 11010812
ISG15 HERC5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16407192 17289916 16815975 16352599
IRF1 IFIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19351818 21056555 20137113
JUN IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20006311 22123848 14734615 15187132 11943142 20304822 17556653 1314139 17105733 22413812 19265145 11801649 16713974 7759501 12836278 15522880 12626576 9558063 8756632 18641343 22351517
MYC IGF2BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21779431 18414489 21252116
IRF1 MYC â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10485906 10820262 11399519 11875494 12417340 12433365 15644117 16127449 16597464 17260466 17689680 18345002 21097505 22461508 23390297 6357187 8871614
VCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22623428 19738201 11751331
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
JUN TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8058069 16327802 16730810 23437118 8183578 16365456 22429882 23936544 15546613 10843986 16978906 23762330 7521696 8631909 12794825
MAPK1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 8072547 11313929 15378002 12531896 12853483 23720779 9662434 1496019 17570479 1922387 11278277 11739718 16023596 20086174 25557171 7737130 26755651 8224842 14676207 17920329 25201974 9022811 22327296 18650425 8137421 18443042 12881422 18572021 17001009 33767435 7744008 23616010 26745678 14617628 11432833 16819515 22606284 12040039
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
MAPK1 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18691976 12478298 19664995 20068231
NPM1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
MAPK13 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17081983 32814053 20385094 11532940 7601337 23331499 15342917 8939914 21071413 23047924 20068231 11335727 9687510 12618428 18988627 18669648 23519423 23109003 18691976 12594221 9915826 17906627 8202512 9430688 19651622 12832467 11500364 14966081 29997244 25730857 8387505 10411321 18212344
MAPK1 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21988832 18156174 12016217 25241761 12832467 23602568 8939914 10480933 9915826 17906627 10980595 10856237 19282669
MYCN MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15917661 15644444 15927364 19649205
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
NCBP1 METTL14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
NCBP2 METTL14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
MYC TGFB1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC TYMS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 18677108
POU5F1 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20505756 12136102 17324942 15988017 17068183
RPS6KA1 YBX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28415756 19036157
RPS6KA3 YBX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22674792 28415756 19036157
TRAF6 TAB3 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF6 TAB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 25290089 14633987 15327770
TGFB1 TRAF6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 24132110 24336330 7594497 9865696
TGFB1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18922473 22710166 19010789 16474430 22943793 17934056 20519943 12809600 21900405 11133108 18758450 14557817 15548370 19920116
RNF8 NDUFAB1 â—¼   KO_DOWN_REGULATES ✅ - -3.51 3.5 PKG 28854368