Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAC3 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17625931
PXN PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 15574420 14665621
KIR2DS4 B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19858347 15265913
HLA-C B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211709 10429675
B2M KIR2DL3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HLA-F KIR2DS4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27649529 24018270
ABL1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
ABL1 DOCK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PAK1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11121037
FLT3 ACAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 34289383
CANX CISD2 â—¼   COLOCALIZATION 2.0 0.8 intact 20010695 7712851
GRB2 CBR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
HLA-B CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9331948 10809759
HLA-C CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12899833 10809759
CDC42 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
CLTC TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
GRB2 DOCK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
GPR182 HLA-C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
GPR37 HLA-C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
PTPN6 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10660620 6671678
GRB2 IMPDH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 GSTM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUFM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
HLA-A KLRD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9405670 9295021
NPSR1 HLA-C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
OPRL1 HLA-C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
HLA-C KIR2DS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24078689 11172020
MYC HLA-F â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8206526
LILRB1 HLA-G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19583775 7144930
HLA-G KIR3DL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21115737 21746965
HSPA5 PSME3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPA5 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YBX1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12446674 8163940
KIR2DL1 PTPN6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6730656 8691146
YBX1 KPNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20596676
MYC LAMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11085504
PTPN11 MET â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18579758 6731904
PAK1 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0701065104 17389360
RAC1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
KIR2DL3 PTPN6 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
GRB2 MET â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
RAC1 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAC2 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
MET ERBB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21918175 25326665
LAMP1 FAM3C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC GANAB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 17314511
RAC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 31980649
PTPN6 KIR2DL3 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 6730623 8648092
MCM3 MYC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYC PCBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
TMED6 NETO2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB ROR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
PCBP1 MET â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RHOC RHOA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 31871319 31980649
HLA-F KIR3DL2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
KLRC1 PTPN6 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
B2M TAPBP â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
HLA-A KIR2DL3 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
RHPN2 RHOA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12221077 31871319 12773565
CD8A CD8B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
PSMA2 PSMA6 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
RHPN2 RHOB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31871319 12473120
HLA-B KIR3DL1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HLA-B KIR3DL2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TAP1 TAPBP â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
B2M KIR3DL1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
B2M KIR2DL1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HLA-A KIR3DL2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
TAP2 TAPBP â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
NUDT21 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
ABL1 GRB2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
PCNA MAD2L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
KIR2DS2 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
CD8A B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15136729 15534202 16551255
KIR2DL1 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
KIR2DL3 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
KIR3DL1 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
CANX B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14681859 2450918 10064069
KIR2DL2 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
CD8B B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15136729 15534202 16551255
KIR3DL2 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
B2M KIR2DL4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
HLA-C DAP10 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
KIR2DL2 DAP10 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ERBB3 RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
MET GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9660480 11439336 8662889 19433454 15546961 11063574 7511210 21222362
KIR2DL2 GRB2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
HLA-C GRB2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
HLA-C KIR2DL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 11513144 21339333 9605119
HLA-C KIR2DL3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 11513144 8574854 9751747
HLA-C PTPN6 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11513144 21339333 9605119
HLA-C PTPN11 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11513144 21339333 9605119
HLA-C IFNG â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
KIR2DL2 IFNG â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
KIR2DL1 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18574028 9751747 19828694
KIR2DL2 PTPN6 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11513144 21339333 9605119
KIR2DL2 PTPN11 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11513144 21339333 9605119
KIR2DL3 PTPN6 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11513144 8574854 9751747
KIR2DL3 PTPN11 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11513144 8574854 9751747
MYC LTA4H â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840 12808131
MYC MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC MSN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12695333 11085504
MYC RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22159222 20383141 22235332
MYC YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12080043 18414489
TAP1 TAPBP â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
PSMB10 PSMD6 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
B2M HLA-F â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
HLA-B B2M â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8624811 5220994
CANX GANAB â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
B2M KLRD1 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
PSMB8 PSMD6 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
PSMB9 PSMD6 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
PAK1 RAC3 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
B2M CD8A â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
GRB2 WIPF1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 21706016 20936779 21988832 28514442
B2M KLRC1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
HLA-E KLRC1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
ERBB3 GRB2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
GRB2 PTPN11 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
PSMB10 PSMB8 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
B2M LILRB1 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
TAP1 TAP2 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
PSMA6 PSMB10 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PSMB10 PSMB9 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
HLA-A TAPBP â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
PAK1 CDC42 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7744004 12879077 23455922 15548653 10802735 24276241 31871319 10684602 21167153 19596003 12606577 10360579 18057010 20936779 11157984 25150978 18426980 21029865 12650940 9705280 8107774 23175184 21048135 31478661 9535855 16678097
B2M LILRB2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HLA-G LILRB2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
KLRC1 KLRD1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
TAP1 TAP2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
RAC1 PAK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5217506 15688026
PSMB8 PSMB9 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
B2M HLA-G â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
B2M HLA-C â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
B2M HLA-E â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PSMB4 PSMD6 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
B2M HLA-B â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
B2M HLA-A â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
PSMA2 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMA6 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
EIF3F EIF3L â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PSMA2 PSMB10 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PSMA2 PSMB9 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA2 PSMB8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA6 PSMB9 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA6 PSMB8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB10 PSMB4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB4 PSMB8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB4 PSMB9 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC42 PAK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PAK1 RAC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA2 PSMB4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMA2 PSMA6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA6 PSMB4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
KIR3DS1 IFNG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12731048 17202323 23715743 24586048 9625766
HLA-C KIR2DS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 28546555 31210416 28484462 18624290 9464792 7650491
CDC42 PXN â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10934474 11248548 11340065 15001467 15003621 15020669 15169870 15882626 16329184 17517963 17785506 18719708 19741094 21178402 22126964 22821962 27248291 7761442 9831565
ABL1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7615549 15817476 11774284 16254239 15107421 12408869 15572663 11695992 15592455 16094384 10823820 20841568 16713569 9603926 7537852
PTPN11 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 23397142 10082579 8986614 10655584 14665621
PAK1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 26598620 10330411 11096073 16717130 14580336 18986306 27542844 28214467 25472536 17440071 23317503
B2M HLA-E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9605335 16189514 10064069 9660937
GRB2 DAP10 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
GRB2 DAP10 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
HLA-C KIR2DS4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 28484462 9521070 15265913 31210416
HLA-C ABL1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
KIR2DL1 ABL1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
HLA-E ABL1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 22464172 2731048 8478617 9485206 9486650 9655483
KLRD1 ABL1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 22464172 2731048 8478617 9485206 9486650 9655483
ABL1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 11726515 16713569 20841568 8596638 16955467 10592173 8647802 8194526 7926767 14725908 23950177 8112292 9407116 23181695 19380743 17474147 9516488 19823681
ABL1 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9826708 12766170 9391119 9242692 10506185 8547236 10069803 7687741 10490849 11741535 21777671 8906793 12475979 9444958 7513258 7961992 15475459 9252406 7838524 7731718 8662889 7708691
ABL1 PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 8692915 8696915 14699166 12468540 10574931 7512963 16497976 20841568 14757045 8114715 10488096
KIR2DL1 CD48 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
HLA-C CD48 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
KIR2DL4 CD48 â—¼   DOWN_REGULATES ✅ - 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
CD48 SH2D1A â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
HLA-G CD48 â—¼   DOWN_REGULATES ✅ - 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
CD48 SH2D1A â—¼   SHARES_COMPLEX 18.0 1.0 ACSN 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26794910 7890616 9535722
HLA-A CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9177355 10809759
HLA-G CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1908512 10843658 10809759
MYC CDC25A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8994810 10205150 11154267 9371770 14519204 15677471 17671423
MYC CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8425218 15121849 11602341 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
WIPF1 CDC42 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11340081 11829459 10878810 12213210 11553796 10781580 11157975
CDC42 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 810774 10360579 21167153 8107774 10559936 9705280 12650940 16678097 23331499 21029865 10684602 18057010 15020669 21070974 11340065 21048135 15003621 20936779 10934474 11413130 15788770 15713627 9535855 23109003 11950587 19628037 7744004 12879077 12606577 24276241 10224076 19596003 8973630 19812368 11248548 10802735 18719708 10613909 10461188 23455922
PAK1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 28007610 12872159 16999872 18354494 20361981 23291169
ERBB3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9756944 24189400 11173924 24658140 14967450 16729043
FLT3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10080542
GRB2 RAC1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 RAC1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
PTPN11 GRB2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10358138 11447289 11572860 12138178 12707331 15240681 15699106 15713798 19833085 9751747
MET GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9660480 15546961 22128289 12475979 11063574 7511210 11439336 8662889
PTPN11 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 8702859 9361008 16371368 21706016 8041791 11085989 8978300 11432792 15882975 9362449 10212213 11684012 7523381 10592173 16189514 10747947 10973965 9632781 8959326 11602579 12577067 9254654 10080542 15010462 31585087 12531430 8995399 19380743 7522233 9804835 7534299 9824671 9660791
GRB2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12522133
HLA-A KIR3DL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11955593 25033772 15580655 15719024 8760804 8617928
HLA-A KIR3DL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 28484462 17182537 31210416
KIR3DL1 HLA-B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
HLA-B PTPN11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
HLA-B PTPN6 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
HLA-B KIR3DL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11955593 15580655 22020283 25480565 8046332 15607823 17182537 25740999 16189514
HLA-B KLRD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8046333 16189514
HLA-B KIR2DL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 28514659 7931060 8760827 19858347
HLA-B KIR3DL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23857132 23804219 28484462 17407096 23440420
HLA-C KIR2DL1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
HLA-C WIPF1 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
HLA-C SH2D1A â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
HLA-C KIR2DL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 11955593 15580655 10497191 9768753 18322206 28484462 15607823 19858347 16189514 8692965 31210416
HLA-C KIR2DL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 30761133 11955593 15580655 10190900 10850706 28484462 18322206
HLA-C KIR2DL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 58.0 1.0 Omnipath 15580655 11163076 10429675 28484462 9686591 9768753 9378975 11323700 12454284 16141329 28546555 11955593 15607823 18624290 11009104 12794140 31519864 19858347 10820396
HLA-E KLRC2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11015446 12731048 20814939 23715743 24586048 2731048 9486650 9625766 9655483
HLA-E KLRD1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 15728498 15884055 20814939 22464172 23715743 24586048 24935923 2731048 8478617 9485206 9486650 9625766 9655483
HLA-E KLRC3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11015446 12731048 15728498 15884055 23715743 24586048 24935923 2731048 9486650 9625766 9655483
HLA-E KLRC2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11015446 12731048 20814939 23715743 24586048 2731048 9486650 9625766 9655483
HLA-E KLRC3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11015446 12731048 15728498 15884055 23715743 24586048 24935923 2731048 9486650 9625766 9655483
HLA-E KLRD1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 15728498 15884055 20814939 22464172 23715743 24586048 24935923 2731048 8478617 9485206 9486650 9625766 9655483
HLA-E PTPN6 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 22464172 2731048 8478617 9485206 9486650 9655483
HLA-E PTPN11 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 22464172 2731048 8478617 9485206 9486650 9655483
HLA-E KLRD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9486650 9886400 14734748 16189514 9815261
HLA-E KLRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9486650 24223577
HLA-E KLRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 26697006 9486650 9103421
HLA-F KIR3DL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 27649529 27455421 28484462
HLA-F KIR3DL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 27455421 24018270 28484462
HLA-G LILRB1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 10591185 11513144 11994457 15771571 16287995 9933109
HLA-G KIR2DL4 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
HLA-G KIR2DL4 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
HLA-G IFNG â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
HLA-G PTPN11 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
HLA-G SH2D1A â—¼   DOWN_REGULATES ✅ - 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
HLA-G KLRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9560253 9295021
HLA-G KLRD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9405670 9295021 16189514
HLA-G LILRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12853576 17056715 19841038 19583775 12874224 28484462 16455647 16189514 15718280 9933109
HLA-G KIR2DL4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11955593 15580655 26973020 17056715 10190900 16487070
MYC HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333 10600159
KIR2DS2 IFNG â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11015446 12731048 20814939 23715743 24586048 9490415 9625766 9655483
KIR2DL4 IFNG â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
PTPN6 IFNG â—¼   DOWN_REGULATES ✅ - 34.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26667266 26755705 27474009 8976179 8986721 9751747 9765283
PTPN11 IFNG â—¼   DOWN_REGULATES ✅ - 34.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26667266 26755705 27474009 8976179 8986721 9751747 9765283
PTPN11 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28065597 23331499 11779860 7642582 10082579 8895367
MYC IMPDH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18628958 18677108
KIR2DL1 PTPN11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
KIR2DL1 SH2D1A â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
KIR2DL1 PTPN6 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
KIR2DL1 WIPF1 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
KIR2DL3 PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8691154 8574854 8648092 9148918
KIR2DL4 PTPN11 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
KIR2DL4 SH2D1A â—¼   DOWN_REGULATES ✅ - 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
KIR3DL1 PTPN11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
KIR3DL1 PTPN6 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
KLRD1 KLRC2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11015446 12731048 20814939 23715743 24586048 2731048 9486650 9625766 9655483
KLRD1 KLRC2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11015446 12731048 20814939 23715743 24586048 2731048 9486650 9625766 9655483
KLRD1 KLRC3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11015446 12731048 15728498 15884055 23715743 24586048 24935923 2731048 9486650 9625766 9655483
KLRD1 KLRC3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11015446 12731048 15728498 15884055 23715743 24586048 24935923 2731048 9486650 9625766 9655483
KLRD1 PTPN11 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 22464172 2731048 8478617 9485206 9486650 9655483
KLRD1 PTPN6 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 22464172 2731048 8478617 9485206 9486650 9655483
RHOA MSN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9856983 15659383 11867620 35267019
MYC PIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC PIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
PIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26655473 15048125 30723410 23716601
RAC1 PAK1 â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11121431 11274345 11544274 11756498 15157156 15229651 18000759 19151919 24459205 27331412 9655398
RAC2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9705280 23331499 10224076
RAC1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 130.0 1.0 Omnipath 17145710 15229651 21167153 8107774 24792722 16551621 14579272 10023776 8805275 18325335 11134022 19693014 19277120 21474670 12650940 15673687 19961560 20711231 11950930 16678097 12123608 19270716 9744077 9148763 11689432 23331499 21029865 16368433 11121431 16492808 15075243 21454543 10592173 24172987 15212766 7493928 10793146 21070974 10706722 8910277 17245428 25819133 20936779 11030651 9989831 15157156 9535855 19359598 25150978 16049136 18854161 19628037 15688026 12879077 7744004 11728826 16002993 9764820 9032259 25843002 10224076 19732720 19596003 10802735 19893577 16212495 11130076 12480336 11152757 19327867 22117219 22581261
PTPN11 PTPN6 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283
PTPN11 PTPN6 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283
RAC1 ROR2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11226259 11274345 11756498 12533515 14704854 14747478 15265686 15618519 17127310 17884187 18000759 18497258 18851840 18953287 19020754 19151919 19565474 19853559 20006983 20093472 20215527 21087212 21380625 21796133 22017973 27331412 7641885 8655584
RAC1 ROR2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11226259 11274345 11756498 12533515 14704854 14747478 15265686 15618519 17127310 17884187 18000759 18497258 18851840 18953287 19020754 19151919 19565474 19853559 20006983 20093472 20215527 21087212 21380625 21796133 22017973 27331412 7641885 8655584
ROR2 RHOA â—¼   PHYSICAL_INTERACTION 53.0 1.0 ACSN 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605
ROR2 RHOA â—¼   SHARES_COMPLEX 53.0 1.0 ACSN 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605
TAP2 TAP1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 10973281 11717192 14508489 16181333 17204652 22076556 22790179
TAP2 TAP1 â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 10973281 11717192 14508489 16181333 17204652 22076556 22790179