Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NOTCH1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10933396 15107403
GORASP2 GOLGB1 â—¼   COLOCALIZATION 2.0 0.8 intact 20608975 7897361
IMMT HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA IMMT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 27153535
MYO9B RHOA â—¼   GTPASE_REACTION ✅ - 0.8 0.8 Signor 32203420
IFNGR1 PRKCD â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
JAK1 PRKCD â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
PRKCD MARCKS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8422248
JUP ARHGDIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
JUP PTPRJ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12370829 6671521
CANX CISD2 â—¼   COLOCALIZATION 2.0 0.8 intact 20010695 7712851
PRKACA ITGAV â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN HMOX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PTPN2 FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22080863
NOTCH1 ITCH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8313469 19567869
HLA-C B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211709 10429675
NGFR RHOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9195882 12692556
CNKSR1 RHOA â—¼   PROXIMITY 2.0 0.8 intact 15670823 5217486
PTPN2 ITGA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15592458 8284715
PTPN2 ITGA1 â—¼   COLOCALIZATION 2.0 0.8 intact 15592458 8284715
ITGA1 PTPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592458
PI4K2A ITCH â—¼   COLOCALIZATION 2.0 0.8 intact 23146885 8426259
PTPN13 EFNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9920925
GNA13 PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10821841
GNA11 GNB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
PRKACA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LNX1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AFG3L2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAB5B HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NCLN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 25942483 1002142
RHOC CNKSR1 â—¼   PROXIMITY 2.0 0.8 intact 15670823 5217486
CTNNA1 PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
CCDC47 PTPRS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PTPRJ MET â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6671721 12475979
GOLGB1 GOLGA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CAV1 RHOA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31871319 20460433 9647788
C1QBP DDX50 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 32877691
CISD2 EMD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 32296183
FAF2 EMD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22119785 34079125
LYN FRS2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 23503679
C1QBP DDX54 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 32877691
CPT1A RHOA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 31871319
RHOA FAT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
RHOA RAP2C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RAB2A CAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26496610
RAB1A RAB2A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26344197
CDH2 CTNNA1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
CXCR4 ITCH â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
GNAI2 MCU â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
EMC7 EMC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22119785 33961781 28514442
EMC7 EMC4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22119785 33961781 28514442
EMC7 EMC8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22119785 33961781 28514442
GNAI3 NDC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HMOX2 CISD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RHOC RHOA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31871319 33961781 31980649
RABL3 RHOA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31871319 33961781
FAF2 CAV1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CXCR4 GNA13 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11994484 23773523
AURKA PEAK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FAF2 ATAD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RAB7A ARL8B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28325809 29360040 26344197
EMC8 EMC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22119785 33961781 28514442
EMC3 EMC4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22119785 33961781 28514442
EMC8 EMC4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22119785 33961781 31536960
CD44 MET â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22897854 28628118 28205554
OSMR JAK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 10586060 33961781
EMC10 EMC4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 32439656
EMC8 EMC10 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22119785 32439656
FYN PRKCD â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
GNAI2 GNB4 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
KPNA1 LMNB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
EHD2 AP2M1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16713569 15182197
KTN1 RHOA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8769096 12773565 31871319 11162552 11689693
FYN PTK2B â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
RAB7A CAV1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
CNNM3 PTP4A3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
AP2M1 BCR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24189400 33961781 26186194 19380743 32203420
EMD LMNB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 17620012 12670476
LYN MET â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 24728074
BCR RHOA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9535855 31871319
DAG1 CAV1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 11724572
CAV1 PTRF â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 22939629 19726876 24013648
FYN CD44 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9573028 16189514 16713569
EMC7 EMC10 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22119785 33961781 32439656 28514442
IL6ST JAK1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
RHOA ITPR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 12766172
RAB7A RAB5B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10329441 26344197
EMC3 EMC10 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22119785 33961781 32439656 28514442
MYO9B RHOA â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
GNAI3 GNB4 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
GNAI2 GNAI3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
AP2M1 NUMB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 23211419 33961781 26186194
DAG1 FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17474147 11724572
ITCH NUMB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20818436 12682059 18628966
RAB1A RAB8A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26824392
RAB7A RAB2A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 26344197 26496610
PTPRJ MET â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12370829 19167335 12475979
CDH2 JUP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RAB1A RAB8A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PRKACA CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16785995
HMOX2 IMMT â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LYN ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11782428
RHOA MYO9B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9490638 11207612 26529257
PRKCD ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11389095 12919677
PRKCD CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10521508 28449947
PRKACA FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20658524
GNAS ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690
GNAS ADCY9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
RHOA ARHGEF12 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
RHOA PFN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22820501 22479341 27228149
CANX B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14681859 2450918 10064069
CXCR4 ITCH â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19116316 34927784 24489825 28264927 22275353
PTPN2 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18819921
PRKACA ARHGDIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18768928
RHOC ARHGEF12 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
PLXNB2 HMOX2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ARHGEF12 RHOA â—¼   GTPASE_REACTION ✅ + 0.91 0.91 Signor 11094164
CTNNA1 JUP â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
JAG1 NOTCH1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
HLA-B B2M â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8624811 5220994
EMC4 EMC8 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CANX GANAB â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
KRIT1 RAP1B â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
RAB1A RAB7A â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CYP51A1 NSDHL â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
GNAI2 GNAI3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22939629 33961781 26186194
ADCY9 GNAS â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EMC3 EMC7 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
EMC7 EMC8 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
EMC10 EMC4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
EMC4 EMC7 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
EMC10 EMC8 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
EMC3 EMC8 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
LNX1 NUMB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16002321 11782429 29121065 14990566 9535908
EMC10 EMC7 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
EMC10 EMC3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ATP1A1 ATP1B1 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ARHGEF12 RHOA â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
B2M HLA-C â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
B2M HLA-B â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
B2M HLA-A â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
ARHGDIA RHOA â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EMC3 EMC4 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
LAMTOR1 LAMTOR2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATF2 LAMTOR2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11274345 12738796 18039929 20506250
PRKACA ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1661585 15105425 92095966
LYN JAK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8197119 16492764 16720384 7512720 10537111
GNAI2 LYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 11160627 10753828 9722546
LYN PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9692543 7575560 15774464 96421649 11812791 20190138 18387943 10319993 15302935 10945993
LYN PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18453587 23109003 12495636 17570479 11311138 7529876 10593973
FYN PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 25241761 11927579 10383400 8621384 28259175 12721299 18387943 10319993
PRKCD IL6ST â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12361954
PRKCD MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17496910 11940581 21386996 7925482 15075332 11447289 19615955 8294430 16488589 6321473 8321321 12845332 11313945 94124523 12040186 19568798 15567848 14585353
FYN JUP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14517306
CXCR4 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
GNAI3 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
ITGAV ITGB5 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGAV ITGB5 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
JAK1 ITGB5 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
ITGB5 ITGA1 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
FYN ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16387660 17053785
FYN ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 14761954 28598420 18056410 8633244
FYN CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 9252391 29371975 11805080 12925753 21705803 12529448 11075810 15692085 14992595 8632005 10592173 16943184 12921535 16332692 12135605 20228056 15466865 33804982 24632723 33928090 18347068 34321069
JAK1 IL6ST â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8390097 9238703 16051226 11943154
JAK1 IFNGR1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IFNGR1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IL6ST JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7896787 23331499 11468294 9388212 21220115 24710148 11742534 23663276 12487370
PTPN2 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 23331499 15588985 15780598 11909529
OSMR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10586060 23331499 15935618
JAK1 IFNGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12133952 8232552 8550631 8156998 7796299 7615558 8649432 19041276
JAK1 PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10702271
PTP4A3 RHOC â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 16540666 17192274 17409395 18268019 20681446 22677902 22825514 23691193 24030100 24376839 25687758 27036022 27452906
PTP4A3 RHOA â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 16540666 17192274 17409395 18268019 20681446 22677902 22825514 23691193 24030100 24376839 25687758 27036022 27452906
NOTCH1 NUMB â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 23343194 24023259 25730849 7542250 8666229
NOTCH1 JAG1 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 23343194 24023259 25730849 7542250 8666229
NOTCH1 NUMB â—¼   PROTEIN_INTERACTION 21.0 1.0 ACSN 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 23343194 24023259 25730849 7542250 8666229
NOTCH1 JAG1 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 23343194 24023259 25730849 7542250 8666229
NOTCH1 NUMB â—¼   DOWN_REGULATES ✅ - 21.0 1.0 ACSN 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 23343194 24023259 25730849 7542250 8666229
NOTCH1 JAG1 â—¼   LOCALISATION ✅ 21.0 1.0 ACSN 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 23343194 24023259 25730849 7542250 8666229
NUMB NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12682059 15358736 16713569 8755477
ITCH NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12682059 10940313 23331499 16713569
JAG1 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 18495817 16921404 15137944 769772111006133 16713569 23331499 21071413 23086448 22363130 18988627 21820430 18292500 18660822 22330899 17537801 11006133 7697721 10958687 22353464
JAG1 NUMB â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 23343194 24023259 25730849 7542250 8666229
JAG1 NUMB â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 23343194 24023259 25730849 7542250 8666229
JAG1 NUMB â—¼   DOWN_REGULATES ✅ - 21.0 1.0 ACSN 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 23343194 24023259 25730849 7542250 8666229
NGF NGFR â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 10764727 11729324 16893414 2172988 1372492 24224055 14985763 22227462 11114882 15258592 14699954 3037029 1714587 9775403
RHOA KTN1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7787244 11933159 8769096 9822636 8912005 11689693
CXCR4 RHOA â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
ARHGDIA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 10489445 20628200 11368848 17353931 9490022 9113980 25416956 20711218 16189514 15659383 14749388 11149925
PRKACA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12654918 21572420 20591975 8599934 16109481 34088899 11162591 15890975
ARHGEF12 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9789025 17145710 15364580 23405219 32203420 9113980 9641915 20300064 10592173 11373293 12515866 11094164 11149925
RHOA CIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8543060 12773565 17332740
RHOA DIAPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22820501 12773565 18218625 16109481 15864301
RHOA KTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12773565 11689693 8769096 11162552
NUMB ITCH â—¼   PHYSICAL_INTERACTION 12.0 1.0 ACSN 10940313 11318614 16469705 16861923 17115028 17312394 18552861 18628966 20818436 20940030 21107885 21383157
NUMB ITCH â—¼   PROTEIN_INTERACTION 12.0 1.0 ACSN 10940313 11318614 16469705 16861923 17115028 17312394 18552861 18628966 20818436 20940030 21107885 21383157
LNX1 NUMB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16002321 9535908 9846878 16713569 11782429
NUMB ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12682059 23331499 20818436 18628966
ITCH CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28264927 19116316 24489825
CXCR4 GNAI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
PRKACA AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 23861900 16222244 16246726 33744274 29764989 26165940 11039908 17545617 27242098 26481147 28869606 26134678 33988677 26831064 33760847 16083426 17895985
AURKA PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19812038
PRKACB NGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12682012 26119933
PTPN12 PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12231407 15588985 11337490
GNA13 ARHGEF12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12515866 11094164 12024019
GNAI2 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
GOSR2 NSF â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
PRKACA RAP1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8463283 19651783 27760305 12089143 1551424 90343822
PRKACA PTPN12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 19651622 18767875 20068231 7520867 94349924 18669648
PRKACA PTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12851456 18669648
PRKACA GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12399457
PRKACA ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 2847175 1847804 8132598 19144319 12529267 14741364
PRKACA PDE3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 26031333 8163498 2839485 10454575 17255105 8626720
BMPR2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18756288 7791754 10712517
OSMR IL6ST â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10692570 23331499 21071413 10854424 18988627 8999038 9188471
PTPRJ MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12370829 15475459 19167335 12475979
EFNB1 EPHB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24003208 15114347 11114742 9330863