Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SHANK3 CYP51A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
CREB1 CYP51A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12145339 16123160
CREB1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11116137
JUN CREM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21757709
SP1 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12706891 8247540
NR3C1 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17016446
JUN RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11604227
SP1 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8887648 19994725
TDG NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129768
SP1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10446206
SREBF2 SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212972 10976766
SP1 EPAS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22402494 17024177
LRRK2 RHOA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21454543 31046837
TREX1 CYP51A1 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
RHOC RHOA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 31871319 31980649
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CREM CREB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25609649 22531917 7809053 16189514
TDG CYP51A1 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CREB1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 2138276
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
JUN ETS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8557686 20195357
SP1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25879517 16478997 17215518 16713569 33572115 10506225
RUNX2 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11274169 11641401
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CREB1 FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15126506
SP1 CREM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21757709 21097497 22281835
SREBF1 CYP51A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12145339 16123160 10551787
JUN ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1945412 8247540
JUN NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 7823959 8733011
SP1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12039077 14962081 15249123
CYP51A1 SC5D â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CYP51A1 NSDHL â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CYP51A1 HSD17B7 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CYP51A1 MSMO1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
FDFT1 HSD17B7 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
FDFT1 SC5D â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
FDFT1 NSDHL â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HSD17B7 LSS â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HSD17B7 MSMO1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
LSS SC5D â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
LSS NSDHL â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MSMO1 SIGMAR1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MSMO1 SC5D â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MSMO1 NSDHL â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
BHLHE40 BHLHE41 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14672706 16462771 16267380 12624110 15147242
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
CREM CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22531917 16189514 7809053 1847666
NR3C1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20203101 16713569 8449898 7621901
ETS1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10942770 12444985 12750007 18374905 12928043
JUN ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8557686 20195357
SREBF2 FDFT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11008488 18413311 11111077 9575211
SREBF1 FDFT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9575211 11111077 9748295 11008488 18413311
SP1 HRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8106522 8208618 3012774 11559711 21931711 8027084 1776841
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
NR3C1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20499359 8639160 2169353 9731701
RUNX2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11641401 11274169
SP1 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19716432 20971080 20179320 24458133 18068676 17449871 15462672 21696544 15330762 22511764
SP1 SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 18068676 10224053
SREBF1 SREBF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14702347 16282353 9786926 11278785
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368