GDF9
|
TDGF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SMURF2
|
SMAD5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMURF2
|
SMAD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMURF2
|
SMAD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMURF2
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22298955
15221015
|
ACVR2B
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
SMAD7
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10564272
23331499
|
ACVR2A
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9748228
8612709
|
BMP8B
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10504300
|
BMPR1B
|
ACVR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
SMAD7
|
ACVR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12857866
12519765
|
SMAD6
|
ACVR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12857866
12519765
|
SMAD6
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12857866
12519765
|
BMPR1B
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
FSTL1
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20860622
7990613
|
SMAD7
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12857866
12519765
|
BMPR1A
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
ACVR2B
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
ATF2
|
RHOB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11160903
21565167
|
AXIN1
|
SMAD7
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16601693
5218493
|
TGFBR2
|
BAMBI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10519551
19758997
|
TGFB1
|
BAMBI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10519551
19758997
|
BAMBI
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10519551
23331499
|
SMAD7
|
BAMBI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10519551
19758997
|
BAMBI
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10519551
23331499
|
SMAD7
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12857866
12519765
|
SMAD6
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12857866
12519765
|
BMP2
|
FSTL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20860622
7990613
|
GATA4
|
BMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23632743
24866243
|
SP1
|
BMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12220517
19009553
|
BMP4
|
FSTL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20860622
7990613
|
SP1
|
BMP4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21411747
17350185
|
SMAD1
|
BMP7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20375015
17127702
|
BMP8B
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10504300
|
SMAD7
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12857866
12519765
|
SMAD6
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12857866
12519765
|
BMPR1A
|
FSTL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20860622
7990613
|
SMURF1
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22298955
17317136
|
SMAD7
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10564272
23331499
|
SMAD6
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10564272
23331499
|
NOG
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22298955
12478285
|
BMPR1A
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10712517
|
BMPR1A
|
SMAD9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19620713
11792802
|
BMPR1B
|
SMAD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12857866
12519765
|
BMPR1B
|
SMAD9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19620713
11792802
|
SMAD6
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12857866
12519765
|
SMAD7
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12857866
12519765
|
NOG
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22298955
12478285
|
SMURF1
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22298955
17317136
|
HRAS
|
CAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8621645
5220985
|
RASA1
|
CAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731661
15504032
|
SP1
|
CD83
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12182451
|
HSP90AA1
|
FANCC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18266962
|
FKBP1A
|
TGFBR2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
2.0
|
0.8
|
ACSN
|
11226255
14766396
|
FSTL1
|
FST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20860622
7990613
|
FSTL1
|
TGFBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20860622
7990613
|
FSTL1
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20860622
7990613
|
NOG
|
GDF5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
21976273
19956691
|
RASA1
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5221569
9219684
|
HSP90AA1
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16888650
5218924
|
HSP90AA1
|
TAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AA1
|
TAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AB1
|
TAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
IFNGR1
|
PRKCD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15322115
11972023
|
PDGFRB
|
IL1R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0510973103
16477012
|
LITAF
|
SMAD5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SP1
|
MAP2K1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17889508
16452190
|
TGFBR2
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16360132
|
TAB1
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215125
11847341
|
MAPK14
|
RUNX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
29057206
20551513
|
OTUB1
|
SMAD9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMAD1
|
RUNX2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19664780
24692107
|
RUNX2
|
SMURF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24631292
23042144
|
SMAD1
|
RUNX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17215250
22298955
|
RUVBL1
|
TAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
RUVBL1
|
TAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
SMAD9
|
SMAD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8893010
11779505
|
SMAD1
|
SMAD5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMURF1
|
SMAD5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMAD9
|
SMAD5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8893010
11779505
|
SMAD7
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10519551
19758997
|
TGFB1
|
USP15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22344298
16027725
|
TGFBR2
|
USP15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22344298
16027725
|
GATA4
|
NKX2-5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
ACVR1
|
BMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
ACVR1
|
FKBP1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
BMPR1B
|
FKBP1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
SMAD6
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
MAPK14
|
TAB1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.8
|
0.8
|
Signor
|
19393267
|
GDF5
|
RGMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
ACVR1
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
MRAP2
|
ACVR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CD83
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
MRAP2
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
RHOB
|
CAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
34079125
|
TAB1
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
5218828
16845370
|
BMPR2
|
BMP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11401330
10504300
|
CAV1
|
BMX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11751885
16189514
|
ZAP70
|
RASA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
7760813
16189514
|
SMAD7
|
TAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12589052
11737269
|
SMURF1
|
SMAD6
|
â—¼ RELOCALIZATION
|
✅
|
-
|
0.83
|
0.83
|
Signor
|
22298955
|
SMAD5
|
ACVR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10652350
10583507
9748228
16189514
|
SMAD7
|
WWP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
ACVR1
|
FKBP1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
RUNX2
|
SMAD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
SMAD1
|
SMAD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
855.0
|
0.85
|
STRING
|
36370105
|
BMP7
|
ACVR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
18070108
8006002
16189514
|
SMAD7
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
18593713
16601693
|
SMAD5
|
RUNX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10531362
22966907
|
ACVR2B
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
SMAD7
|
SMAD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26555259
9256479
|
ACVR2B
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
SMURF2
|
SMAD7
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.87
|
0.87
|
Signor
|
18448069
|
SMAD7
|
SMURF2
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
19352540
|
SMURF1
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
BMP4
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
BMPR2
|
BMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
7644468
7791754
|
GDF5
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19229295
9525338
|
BMP2
|
BMPR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
PDGFRB
|
RASA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
HSP90AA1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
BMPR2
|
ACVR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
7890683
7791754
28514442
|
RGMB
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15671031
25938661
|
BMPR2
|
BMP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
7644468
12045205
28126904
8702914
7673243
|
SMAD6
|
SMAD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9256479
12857866
9436979
11483516
|
TGFBR2
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
8044119
21054789
|
BMPR1A
|
GDF5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
SMAD1
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
ACVR2A
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
SMAD5
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
SMURF1
|
SMAD7
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
12519765
|
SMAD7
|
SMURF1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
19352540
|
TAB1
|
TAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
BMPR1B
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12151385
12857866
11278251
|
TGFBR2
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15496141
11163210
11278251
|
ACVR2B
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12151385
12857866
11278251
|
BMPR2
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12151385
12857866
11278251
|
ACVR2A
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12151385
12857866
11278251
|
BMP2
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12151385
12857866
11278251
|
TGFB1
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15496141
11163210
11278251
|
BMPR1A
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12151385
12857866
11278251
|
SMAD6
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23455153
23331499
10564272
|
ACVR1
|
SMAD9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10583507
16189514
11792802
|
ACVR2A
|
ZFYVE16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17356069
8893010
9136927
|
ACVR2A
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12151385
12857866
11278251
|
ACVR2B
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12151385
12857866
11278251
|
ACVR2B
|
ZFYVE16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17356069
8893010
9136927
|
ACVR2B
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
17295905
16446785
|
SP1
|
ATF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2145272
12760745
|
ATF2
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17258390
22542937
15546613
|
AXIN1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16601693
|
BMPR2
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25938661
7791754
10712517
10880444
|
BMP2
|
ZFYVE16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17356069
8893010
9136927
|
BMP2
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12151385
12857866
11278251
|
NOG
|
BMP4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10657699
12700180
11706034
|
BMPR1A
|
ZFYVE16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17356069
8893010
9136927
|
BMPR1A
|
FAM83G
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24554596
|
BMPR1B
|
GDF5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
BMPR1B
|
ZFYVE16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17356069
8893010
9136927
|
SMAD6
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10564272
23331499
15761153
|
SMAD7
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10564272
23331499
15761153
|
BMPR2
|
ZFYVE16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17356069
8893010
9136927
|
CAV1
|
PDGFRB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10066366
11168929
23331499
|
FKBP1A
|
TGFB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11960000
23734213
|
HRAS
|
HSP90AA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16024644
15118125
15284455
|
SP1
|
IFNGR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11477089
17339358
|
TSC22D1
|
OTUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SMAD1
|
TNFRSF11B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11139569
14672939
|
SMURF1
|
SMAD6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11278251
22298955
29950561
|
WWP2
|
SMAD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21258410
31546607
22773947
|
SP1
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16714330
10843994
|
TGFBR2
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15496141
11163210
11278251
|
TGFB1
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15496141
11163210
11278251
|
FBP1
|
FBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
BMP4
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
BMP7
|
NOG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
ACVR2A
|
BMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
ATF2
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
ACVR2A
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
MAPK14
|
TAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
BMPR1A
|
BMP2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
19804412
7261592
|
SMAD7
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
BMP2
|
RGMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
HRAS
|
RASA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
SMAD1
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
SMAD7
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
BMP2
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
MAP3K7
|
TAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
GDF9
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12135884
10712517
|
GDF9
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12135884
|
GDF9
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12135884
|
GDF9
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
1213588412135880
12135884
|
BMP10
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16049014
|
BMP10
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
BMP10
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
30246251
30246252
27252362
31127068
|
BMP10
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15621726
16049014
|
BMP10
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15621726
31127068
16049014
|
BMP5
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11580864
16189514
|
SMAD7
|
SMURF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
26435193
22773947
15231748
23331499
22921829
16641086
17719543
21791611
26679521
11163210
27292644
20937913
15221015
18448069
22624557
32283253
23973329
16061177
14722617
19352540
|
SMURF2
|
SMAD5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
20484049
15221015
22298955
15231748
|
SMURF2
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
14701756
23331499
15221015
11016919
22298955
11158580
32296183
15231748
20937913
|
GDF2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
27252362
19996292
|
AMH
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14656470
|
BMP2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8006002
28977600
|
BMP6
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12297674
|
BMP7
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11282024
8006002
31619522
122976748006002
16189514
12297674
|
BMPR2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
7791754
7890683
|
ACVR1
|
SMAD5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9748228
23331499
10652350
10583507
16189514
11792802
10504300
|
ACVR1
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
19651622
9748228
23331499
9335504
10085121
10652350
9136927
10583507
16189514
11792802
18988627
|
ACVR2A
|
GDF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
BMP2
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17483092
10880444
21702718
17295905
25938661
20959140
|
BMP6
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10504300
|
GDF5
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8702914
|
BMP7
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
9748228
7790373
12667445
|
GDF2
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22622516
19996292
|
TDGF1
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
12682303
|
GDF7
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
GDF1
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
GDF2
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15851468
27252362
26047946
|
BMP7
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9748228
23331499
16446785
|
GDF5
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
8702914
16446785
|
BMP2
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
20385559
16446785
28977600
15064755
18988627
17295905
|
BMP6
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
10504300
|
MAPK14
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
104.0
|
1.0
|
Omnipath
|
17081983
18767875
21098032
20506250
26359454
19690332
11060298
19413330
12788955
10085140
22037767
11566021
17079470
19647037
10581204
10777545
7535770
23331499
7839144
19324872
21071413
21614932
20068231
16393692
15304344
17570479
17380123
18988627
7737130
18669648
15187187
9305639
7737129
15140942
602896
11896587
17548358
12110590
7824938
8663524
33893075
12024021
11078583
11971971
9707433
17258390
10821277
19651622
19436832
11259586
27726305
11781825
9430721
27142525
10909971
12118074
15569672
15212693
9753474
11274345
10903740
26987986
|
SMAD1
|
BMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
14551209
11786386
21471203
19836350
11585340
22072987
|
NOG
|
BMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10657699
12700180
19804412
15064755
|
BMP2
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10880440
23331499
11263668
23180781
18342887
16446785
10880444
10712517
7791754
17295905
25938661
24337809
|
BMP2
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
51.0
|
1.0
|
Omnipath
|
17145710
17483092
10880444
10712517
26330344
21054789
16672363
10881198
11263668
20860622
15064755
18937504
25938661
15621726
12700180
10692589
19804412
|
BMP2
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
7811286
12700180
9872992
10712517
15064755
19229295
|
BMP4
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
8702914
26330344
20860622
21054789
11241215
8006002
16189514
7644468
|
BMP4
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7811286
8702914
11282024
8006002
|
BMP4
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
8702914
23331499
21071413
16446785
12045205
8006002
7673243
7644468
|
BMP6
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
11401330
10504300
|
BMP6
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11401330
12297674
10504300
|
BMP6
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11401330
10504300
|
NOG
|
BMP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17145710
12478285
|
BMP7
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15621726
106311828605097
8605097
10631182
|
BMP7
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16189514
7791754
12297674
8605097
|
BMP7
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
18342887
16446785
7791754
7644468
|
CTDNEP1
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
17141153
|
GDF7
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
GDF5
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
21543859
9525338
11282024
16127465
19229295
|
BMPR2
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18756288
7791754
10712517
|
GDF6
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9525338
160490149525338
16049014
|
BMPR1A
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11438941
24412244
19620713
9136927
16189514
11792802
|
GDF5
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8702914
15890363
9525338
11282024
16127465
15569154
19229295
|
BMPR2
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
18756288
10712517
7791754
|
BMPR1B
|
SMAD5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
19620713
9766532
11792802
|
BMPR1B
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
9748228
23331499
9335504
10085121
19620713
9766532
9136927
11792802
15212693
|
GDF2
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
28646109
15851468
|
GDF5
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8702914
23331499
9525338
23180781
18342887
16446785
19229295
87029149525338
|
GDF6
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
9525338
16446785
18988627
160490149525338
16049014
|
GDF7
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
CAV1
|
TGFBR2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
11102446
17517963
18458534
19411448
20855962
21051947
21150282
21729786
22411312
22874531
23907124
25364523
26828520
|
SP1
|
CAV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15531587
10684646
23280667
21631282
17108117
|
CDK8
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19914168
19914161
|
TGFB1
|
FKBP1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
20207738
7823948
21358634
23525077
|
TGFBR2
|
FKBP1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
20207738
7823948
21358634
23525077
|
NKX2-5
|
GATA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19479054
15653675
16137232
|
TDGF1
|
GDF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
SP1
|
HRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
8106522
8208618
3012774
11559711
21931711
8027084
1776841
|
RASA1
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
10769036
11389730
23331499
18829532
7628625
9219684
10592173
8663024
16713569
26721396
8360177
8537347
1904555
10394594
2833817
|
SP1
|
IGFBP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12200149
11517158
15247904
|
MAPK14
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15187187
18039929
12738796
11274345
12697810
|
TAB2
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
25.0
|
1.0
|
ACSN
|
10391247
11280761
11460167
11477091
12620219
14633987
14660645
15082531
15125833
16603398
16799562
17301840
17363905
18264787
18641653
19161412
20164171
21041997
21133840
21232017
22941947
23681101
24403530
24699077
24958845
|
TAB2
|
MAP3K7
|
â—¼ SHARES_COMPLEX
|
|
|
25.0
|
1.0
|
ACSN
|
10391247
11280761
11460167
11477091
12620219
14633987
14660645
15082531
15125833
16603398
16799562
17301840
17363905
18264787
18641653
19161412
20164171
21041997
21133840
21232017
22941947
23681101
24403530
24699077
24958845
|
TAB1
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
17145710
16289117
18180283
10838074
24912525
23934659
10882101
19556242
11259596
19026643
14670075
17299140
23331499
22158122
12372426
21903422
17560374
21071413
23180781
19775907
14743216
17348859
20200282
26432169
18988627
10094049
8638164
11809792
10702308
25241761
19232515
14633987
18456659
10921914
20538596
15590691
16845370
27468689
12975377
12242293
17172402
22167179
12429732
12624112
12859960
16260783
11460167
|
SMAD7
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12589052
|
SMAD6
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11737269
10748100
|
TAB2
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
112.0
|
1.0
|
Omnipath
|
17145710
11477091
17301840
18180283
10838074
24912525
16251197
10882101
19556242
15125833
19955178
31250519
36130827
17363905
17158449
11259596
19026643
24699077
14670075
18641653
24061540
24403530
23331499
22158122
12372426
21903422
27426733
21071413
23180781
14743216
18021073
21133840
20200282
26432169
21232017
18264787
20194509
10391247
18988627
22081109
8638164
16799562
11809792
19232515
12620219
14633987
19161412
20538596
22941947
23681101
20932475
15590691
12609980
16845370
27468689
12242293
11280761
15082531
26192618
14660645
24958845
17172402
15327770
25642820
22167179
20164171
16603398
17384642
11460167
21041997
|
MAP3K7
|
MAPK14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12589052
17965022
15692051
17947236
|
ZAP70
|
MAPK14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23109003
26390817
15735649
15735648
|
MAPK14
|
TAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
28.0
|
1.0
|
Omnipath
|
24443058
22216226
33204339
19393267
25241761
11847341
16648477
12429732
14592977
22307082
17570479
26391660
17126905
21900206
|
PDGFRB
|
RASA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
11896619
1375321
23331499
8382774
1314164
7486683
1850098
10697503
16713569
|
SMURF1
|
RUNX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17145710
14701828
16299379
12738770
|
SMAD1
|
SMAD6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10692396
17215250
22219353
22072987
|
SMAD6
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23331499
9256479
9335505
9436979
21071413
18988627
11483516
12857866
|
SMURF1
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
14701756
17676934
15221015
19914168
21708152
22298955
24828823
19917253
16611643
17510966
15761153
22670624
22152476
17289590
15231748
21685363
27447855
|
SMAD5
|
SMAD6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10692396
16436528
22219353
|
SMURF1
|
SMAD5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17676934
20484049
11278251
15221015
19914168
22298955
18641638
22670624
15231748
12857866
|
SMAD6
|
TAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
11737269
|
TGFB1
|
SMAD7
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
11133108
11708773
12490555
14557817
15111329
15181457
15252039
15548370
16474430
16607286
16716598
17615296
17934056
18403754
19010789
19109155
19920116
20519943
20644162
21041997
21278795
21900405
21909923
22703233
7594497
9157999
9335507
|
SMAD7
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10887185
15855807
9886263
20631490
22656308
19214138
23633623
14600158
10753944
11912247
11385614
11180003
17928287
19010789
22496417
22841502
17074765
15496141
11448947
|
SMURF1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
22773947
12151385
23331499
22921829
21071413
18988627
11278251
12408818
12519765
22152476
27292644
20937913
15221015
24700460
14722617
16720724
23959799
|
TGFB1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19010789
14718519
16474430
17934056
20519943
9335507
21900405
11133108
14557817
15548370
19920116
|
TGFBR2
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11278251
15221015
11163210
|
SMAD7
|
TAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
11737269
|
SMAD7
|
TAB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
17384642
|
SMURF1
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11278251
15221015
22298955
15761148
21572392
27048878
22949611
|
SP1
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12186868
9580699
2808430
12615726
22415074
27974707
12138160
10964912
9242631
15178441
23437118
23936544
11114293
8325508
16714330
11278686
10212284
9837963
11054406
23806282
15979845
|
SP1
|
TGFBR2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18053089
11507078
22028617
15647279
11687969
10982796
12750289
15895377
10766860
9632722
15905358
|
TAB2
|
TAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
10391247
11274345
12620219
14660645
14704854
14960582
15082531
17127310
17884187
18264787
18762249
18855897
19020754
19136967
20194509
23070005
|
TAB2
|
TAB1
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
10391247
11274345
12620219
14660645
14704854
14960582
15082531
17127310
17884187
18264787
18762249
18855897
19020754
19136967
20194509
23070005
|
TGFB1
|
TGFBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR2
|
â—¼ SHARES_COMPLEX
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
122.0
|
1.0
|
Omnipath
|
1310899
22874531
8047140
11279127
22710166
7878020
16424049
17673906
24132110
18922473
22943793
12729750
16446785
20519943
7706250
15761153
7594497
15548370
15761148
15265520
19010789
26194464
7852346
12717440
17768418
19050695
11133108
14557817
11278410
19920116
22949611
22703233
23331499
23070005
20060931
17070508
21614932
1333888
10716993
16572188
20860622
11323414
21900405
12724770
8106553
23034983
26192618
2871107
12809600
11382746
21372296
20538542
16200688
11792802
26201938
24403530
15099563
11013220
17979848
21054789
23784029
15003992
20644162
8515656
7935686
11157754
20856203
18382895
15282297
18855897
9865696
21441952
10678166
16127449
21041659
10026191
22315516
12767520
17404308
19732719
20616810
21071413
17934056
12738796
18423981
21098712
19747910
9311995
15034927
11274345
12154066
18758450
24336330
21278795
26966341
9261125
16474430
15653932
18490733
8242742
19038247
19109155
|