Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HGS TOM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15611048 5217420
BMPR1B ACVR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7644468 7791754
BMPR1B ACVR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7644468 7791754
BMPR1A ACVR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7644468 7791754
ACVR2B BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16446785
BMPR1A BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10712517
BMPR1A SMAD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19620713 11792802
BMPR1B SMAD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19620713 11792802
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
STAM2 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HGS UBAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ZFYVE16 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
SPTAN1 ZFYVE16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STAM2 TSG101 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 UBAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
PTPN23 ZFYVE16 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
EPHA7 EPHA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FGFR2 FGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EPHA4 FGFR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16365308 18790757
RNF11 STAM2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15231748 32814053 16713569 24377927 23222715 16189514
ACVR2B BMPR1A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR STAM2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10993906 11687594 15212941 17403676
TSG101 UBAP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ACVR2B BMP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
BMP2 BMPR1B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ACVR2A BMPR1A â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
ACVR2A ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
ACVR2B ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
ACVR2B BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 17295905 16446785
BMPR2 BMP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25938661 7791754 10712517 10880444
BMP2 ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
BMPR1A ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
BMPR1B ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
BMPR2 ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
PTPN23 STAM2 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
ACVR2A BMP2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PTPN23 UBAP1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
BMPR1A BMP2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 19804412 7261592
HGS STAM2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
BMP2 BMPR1A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
HGS TSG101 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
BMP2 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17483092 10880444 21702718 17295905 25938661 20959140
BMP2 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 20385559 16446785 28977600 15064755 18988627 17295905
SMAD1 BMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14551209 11786386 21471203 19836350 11585340 22072987
BMP2 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10880440 23331499 11263668 23180781 18342887 16446785 10880444 10712517 7791754 17295905 25938661 24337809
BMP2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 51.0 1.0 Omnipath 17145710 17483092 10880444 10712517 26330344 21054789 16672363 10881198 11263668 20860622 15064755 18937504 25938661 15621726 12700180 10692589 19804412
BMP2 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7811286 12700180 9872992 10712517 15064755 19229295
BMPR2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18756288 7791754 10712517
BMPR1A SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11438941 24412244 19620713 9136927 16189514 11792802
BMPR2 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 16446785 18756288 10712517 7791754
BMPR1B SMAD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 19620713 9766532 11792802
BMPR1B SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9748228 23331499 9335504 10085121 19620713 9766532 9136927 11792802 15212693
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
TP53 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22466965 18811981 16557594 24492005
PDGFRB PDGFRA â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFRB PDGFRA â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFRB PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 21071413 2161888 2542288 7523122 1847074 16189514 11331882 10417313
TP53 PDGFRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19952113 19763735 18697203
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
PPP1CC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17274640 15178317 16501611