Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NUP58 STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NUP58 VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VPS37B VPS28 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 8153045 21516116
STAM2 VPS28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS VPS28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM VPS28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
VPS28 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VPS28 TSG101 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ARRDC3 HGS â—¼   COLOCALIZATION 2.0 0.8 intact 23208550 8428323
DAZAP2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ZC3H10 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 ZC3H10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 STAMBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 CCT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LMNA CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDGFRB CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731806 17620338
ITCH CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12226085 5215735
HTT CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CBL MET â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5215187 11894096
CBL FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBL SH3GL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11894095 16713569
CBL FGFR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBL FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
MYC CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT5 STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT5 STAMBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT5 TIMM8A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CDC7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
UBQLN4 DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
STAM2 DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DAZAP2 ZFYVE9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
DAZAP2 RPS27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DAZAP2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DAZAP2 UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
DAZAP2 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
EGFR HRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR PTPN1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 9355745 6671413
SH3KBP1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11894095
UBE2D3 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
UBE2D1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
UBE2D2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
EGFR HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
GRB2 EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
UBQLN1 EPS15 â—¼   COLOCALIZATION 2.0 0.8 intact 5219302 17082820
FGFR1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9480847 16713569
MYC FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TGOLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
STAM2 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VPS37C HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
UBQLN1 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HGS UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HGS VPS37D â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS MVB12B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS MVB12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS UBAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS VPS37B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
MET HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 8380735
HRAS VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPS27A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2H HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VPS37A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT TIMM8A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
RNF11 ITCH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8012720 20676133
ITCH SH3GL2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5216835 14684745
SH3GL2 ITCH â—¼   COLOCALIZATION 2.0 0.8 intact 5216835 14684745
JAK1 STAM2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 10993906 5213009
PDGFRB JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8657151 9484840
STAM2 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10899310 16713569
UBQLN4 KLHL42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
KLHL42 UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
L3MBTL2 STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
L3MBTL2 PHF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MYC LAMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11085504
STAM2 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PTPN1 MET â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18579758 6731904
PTPN1 MET â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6764906 16537444
STAM2 MVB12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM MVB12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 MVB12B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM MVB12B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
MYC UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC PDGFRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15226411 18697203
WFS1 PRPS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPS1 STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPS1 VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PTPN23 ZFYVE9 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBA52 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ZFYVE16 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBQLN2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ZFYVE9 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBE2D2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBC RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 RPS27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 SH3KBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 RPS27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 SH3KBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SH3KBP1 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBA52 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VPS37A STAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
VPS37D STAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
VPS37C STAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM VPS37B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM TSG101 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
STAM UBAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
UBQLN4 STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
WFS1 STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAMBP STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
STAM2 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
STAM2 VPS37B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 TSG101 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 UBAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 VPS37D â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10899310 16713569
UBB STAMBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAMBP UBC â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
WFS1 TIMM8A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22842904 21857666
UBQLN2 UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
WFS1 VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBC UBQLN4 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
EGFR JAK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
GRB2 MET â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ITCH RPS27A â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
GRB2 RET â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
PTPN23 ZFYVE16 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
MYC RPS27A â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
GRB2 VPS28 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UBQL1 STAM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16159959 32296183
UBQL2 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 30442662
UBQL2 HGS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33277362 32296183
STAM2 UBQL2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33277362 32296183
NTRK1 CBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21570973 25921289
EGFR LMNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24780295 26320552
EPHA7 EPHA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FGFR2 FGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LITAF FGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LITAF FGFR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PTPN1 JAK2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 6732089 11970898
PTPN1 JAK2 â—¼   DEPHOSPHORYLATION ✅ 0.82 0.82 mint 6673264 15821101
JAK2 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 0.82 0.82 mint 8287447 201095 21806020
LITAF UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC XRN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
RNF11 UBC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15231748 20676133
GRB2 PDGFRB â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
RPS27A STAMBP â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
UBB UBE2D1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
VPS28 UBAP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 21757351 26186194 28514442 31203368 24284069 22405001
HGS UBQL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16159959 16189514 16713569
UBQL2 UBQL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16813565 32296183 30442662
CBL ITCH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12226085 19341794
EGFR EPHA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15657067 24797263
EPHA4 FGFR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16365308 18790757
RNF11 EPS15 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 14755250 24377927 23222715
EPS15 STAM2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12551915 16713569
STAM2 JAK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16713569 10899310
STAM2 LCP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25416956 32296183 17235283
MYC LMNA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
PRPS1 UBB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SH3KBP1 UBB â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CBL LCP2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CBL UBE2D1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
UBQL1 UBC â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20059542 19798103
UBC HGS â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 12750381 5216384
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
STAM UBB â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
STAM2 UBB â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
ARRDC3 UBA52 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
RPS27A UBQLN1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
EGFR RIN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12783862 17403676
EPHA7 EPHA2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 22036564
STAM2 JAK3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 10899310
RNF11 STAM2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15231748 32814053 16713569 24377927 23222715 16189514
STAM2 TYK2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 10899310
CBL EPHA2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
TSG101 VPS37D â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
JAK2 PTPN1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
UBC UBQLN2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
RIN1 STAM2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22976291 17403676
MET CBL â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 6538879 18273061
MET CBL â—¼   UBIQUITINATION ✅ 0.86 0.86 mint 11894096 5215187
EPHA7 EPHA3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 28514442 22036564
FGFR3 GRB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9045692 26344197
STAM USP8 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
RIN1 HRAS â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 34591612
STAM2 PTN23 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23477725 26866605
EGFR NTRK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR STAM2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10993906 11687594 15212941 17403676
MYC UBC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 16996503 19131971
UBB RNF11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 14755250 33961781
TSG101 UBAP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
UBAP1 VPS28 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EGFR SH3KBP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
UBAP1 VPS37A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
PARK2 SNCA â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GRB2 STAMBP â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ITCH UBE2D3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
UBA52 UBE2D2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
UBA52 UBE2D1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EGFR USP8 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EGFR SH3GL2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
LCP2 CBL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9716598 10204582 19635790 10477741
JAK2 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24240702 23838182 9363897 10358079 10635327 16273093
EPS15 GRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17474147 7797522 19109251
FGFR2 FGFR3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 23972473
JAK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8536716 11527382
EGFR EPS15 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
STAM STAMBP â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ARRDC3 UBE2D1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
PARK2 UBE2D2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
EGFR MET â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
EPS15 HGS â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SH3GL2 SH3KBP1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
HRAS RIN1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
GRB2 LCP2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
STABP GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 20159979 33961781 21706016 12810066 19615732 20936779 26186194 16730941 25416956
RNF11 STABP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32814053 14755250
PTN23 UBAP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27839950 21757351 26456826
CBL UBC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
EGFR LCP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
RET GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7665556 10995764 15677445 9393871 8183561 32062451 16189514
NTRK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10748052 11733534 25921289
STAM2 JAK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10993906 16713569 10899310
UBC UBE2D3 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
TSG101 VPS37C â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
HGS RPS27A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
PARK2 UBE2D3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
EGFR PTPN1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
FGFR2 GRB2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
TSG101 UBA52 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ITCH UBC â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
UBQL1 EPS15 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18199683 16159959 17082820
GRB2 PTN23 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26344197 20936779 21179510 28675297 28514442
EGFR CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23158001 24797263 25872741 31182136 10635327 26055326 14505571 15210722 32714745 23774213 19155296 11370743 19836242 8665853 19947936 18271526 25140053 15668240 22394513 17486068 33323455 32377695 22203672 17182860 12604776 14627991 15383614 23153581 15735736 28541302 16849543 17242169 20562913 32904620 9121472 15677445 7782294 16923119 17995934 19531499 15465819 31959764 32114396 23457600 29629558 18316398 23799367 24714105 31120930 12061819 16713569 7657591 33617900 10086340 19225046 33762435 23175185 16729043 28791635 16246327 28198003 15962011 22266821 15117950 27059931 10428778 12734385 8662998 25005938 27903975 16969069 26177020 8798643 10799548 9756944 15159412 19578043 15657067 18255265 23418353 25754235 22976291 17545148 12803489 18319245 19713535 7592693 30544639 15107835 11994282 17971399 16105874 15282549 20940296 23897813 9130710 18273061 18508924 17880946 20124286 12593795 16914641 20877636 10092522 25521828 11408594 22591401 9890970 20308550 22833562 21772844 33627783 11239464
MYC CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CCT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
UBA52 DAZAP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PTPN1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 6671413 9355745
PTPN1 EGFR â—¼   PHOSPHORYLATION ✅ 0.9 0.9 mint 6671413 9355745
PTPN1 EGFR â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 6732094 9050838
EGFR PTPN1 â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 25796184
EGFR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8524316 15284024
PTPN1 EPHA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21135139
MYC FGFR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PDGFRA GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
JAK2 GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8536716 17474147 8950973 7500025
MET GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9660480 11439336 8662889 19433454 15546961 11063574 7511210 21222362
JAK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8536716 11527382
MET HGF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18593464 20624990 19433454 22897854 8380735 15167892 16537482 17981115 28205554 17804794 28628118 1846706 18495663 1655405
HGS ZFYVE9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 11094085
SH3GL2 LCP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC LMNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC UBA52 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PTPN1 STAM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20504764
UBE2D3 UBA52 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ARRDC3 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PARK2 UBA52 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ITCH UBE2D2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
RPS27A STAM2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
UBC USP8 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
EPS15 UBC â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
UBB UBE2D2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
RPS27A UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
UBB UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
MVB12B VPS28 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
CBL MET â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
RPS27A UBE2D1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
PARK2 RPS27A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
UBA52 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
UBP8 GRB2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 10982817 13129930
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
VPS28 VPS37A â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CBL SH3KBP1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
STAMBP UBC â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
KLHL42 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
RNF11 UBE2D1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
RPS27A SH3KBP1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
TSG101 UBB â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
TSG101 VPS37A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MVB12B VPS37B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PTPN23 STAM2 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
RPS27A UBE2D2 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
UBC UBQLN1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
RPS27A UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A STAM â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PARK2 UBB â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
MVB12B TSG101 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
HGS UBC â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PTPN23 UBAP1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MVB12A VPS37B â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
UBC UBE2D1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
STAM2 UBP8 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 13129930 16713569 20736164 29604273 10982817
STABP STAM2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 20159979 27725184 10899310 16713569 16730941 16189514 19060904
SH3KBP1 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6170483 15090612
LCP2 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10224278 8695800 32296183 19380743 9565634 11314042 7706237 20936779 12176364 10204582 8995445 25416956 9716598 15929943 17235283
RPS27A TSG101 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
HGS STAM2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SH3KBP1 UBC â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
STAM2 STAMBP â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MVB12A TSG101 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
UBC UBE2D2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CBL UBE2D2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
STAM UBC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
SEC13 SEC31A â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
STAM2 UBC â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
VPS28 VPS37B â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
TSG101 UBC â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MVB12A VPS28 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HGS TSG101 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS27A UBA52 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PARK2 UBC â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HGS STAM â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
TSG101 VPS28 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TSG101 VPS37B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RIN1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 11784866 9144171 24441586 34591612 15031288 15886098 7862125 10545207
VPS37C VPS28 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37A VPS28 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37D VPS28 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
TSG101 VPS28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 26871637 19060904 26186194 11134028 15218037 25416956 21757351 11916981 31515488 16189514 32296183 12663786 14505570 24284069
STAM2 CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
HGS CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
CBL STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
SH3KBP1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 20130058 20711168 12618476 11894095 16407834 16713569 11071869 19268472 25472714 17306257 22262777 15456872 11152963 10679202 15962011 25036637 15107835 22833562 11067845 11894096 12177062 17675467 21830225 12135478 24167568 16228008 12874286 17072306 15090612 14596919
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CBL PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 9234717 10347229 18988627 17635922 10514377
CBL MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16397241 15123609 23331499 25241761 21222362 11894096 18672314 21163258 19450681 18273061 35309168 17533376 19433454 17635922 10514377
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CBL RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12727845 15677445
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
USP8 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16520378 16120644 25853104 20736164
JAK2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17389395 10635327 17081983 10358079 16273093 16799092 18691976 10459005 9363897 15284024 23838182 17016520 18669648 15302935
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 17389395 10953014 24269888 19534553 25260758 19583965 19690332 15951569 9049247 17016520
EGFR PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 25796184 31980649 8621392 12573287 18253097 11106648 11506178 24658140 7540771 9050838 9355745 15982634 25402006 10889023 7693694 8999839
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
HGF EPS15 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
MET EPS15 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
EPS15 SH3KBP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
EPS15 SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
EPS15 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7797522 17474147 19109251
FGFR1 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
HRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
FGFR2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22726438 19735729 26103942 20554525 23420874
FGFR4 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
HRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HGS GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
STAM2 GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
GRB2 LCP2 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
MET GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9660480 15546961 22128289 12475979 11063574 7511210 11439336 8662889
PDGFRB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7935391 16713569 7486683
JAK2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8536716 8950973 7500025 17474147 19273609
NTRK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733534 10748052
RET GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9393871 16189514 15677445
LCP2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 7706237 20936779 10224278 8695800 17235283 15929943 25416956 19380743 9716598 32296183 10204582 11314042 8995445
GRB2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17496910 16713569 17673906 11352655
HGS HGF â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
STAM2 HGF â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HGF STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HGF MET â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11290563 12649206 15059978 16212809 17145802 18633355 19631971 20303741 22763439 23402812 23667593 26366398 26819959 27474009 28475121 9242465
HGF MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 17145710 22897854 15167892 1655405 20624990 19433454 23331499 17804794 1846706 28475121 22001117 16537482 15218027 27147579 24362531 17667909 16397249 20178463 17981115 28534512 8380735 18495663 14685170
HGS SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
RNF11 ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14559117 19131965
ITCH SH3GL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14684745 17038327 26613292
JAK1 TYK2 â—¼   PHYSICAL_INTERACTION 85.0 1.0 ACSN 10433356 10485906 10542212 10623821 11160275 11207245 11306493 11371360 11698286 11867689 11870632 11875494 11964292 12223527 12401408 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 14764699 15099563 15282297 15356132 15573129 15579430 15864272 16200688 16243976 16413922 16424049 16713974 17404308 17485448 17513775 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21097505 21115385 21191065 21220452 21469115 21840487 21930765 21930769 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545
JAK1 JAK2 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 JAK2 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 TYK2 â—¼   SHARES_COMPLEX 85.0 1.0 ACSN 10433356 10485906 10542212 10623821 11160275 11207245 11306493 11371360 11698286 11867689 11870632 11875494 11964292 12223527 12401408 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 14764699 15099563 15282297 15356132 15573129 15579430 15864272 16200688 16243976 16413922 16424049 16713974 17404308 17485448 17513775 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21097505 21115385 21191065 21220452 21469115 21840487 21930765 21930769 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545
JAK3 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11641425 19901323 20135364 17259970 12207328 10825200 11909529 15659558 12559972 9553136
JAK1 STAM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10899310 10993906 16713569
JAK1 TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8702790 19901323 7504784 7589562 15659558 30029643
JAK2 TYK2 â—¼   PHYSICAL_INTERACTION 73.0 1.0 ACSN 10485906 10807786 11160275 11306493 11371360 11867689 11870632 12223527 12244147 12372421 12401408 12496409 12754507 12818165 1439146 14610620 14657224 15099563 15356132 15546391 15573129 16243976 16413922 17404308 17485448 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21042762 21097505 21115385 21469115 21840487 22077060 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24204259 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8683106 8700208 8837607 9535722 9834059 9845545
JAK2 TYK2 â—¼   SHARES_COMPLEX 73.0 1.0 ACSN 10485906 10807786 11160275 11306493 11371360 11867689 11870632 12223527 12244147 12372421 12401408 12496409 12754507 12818165 1439146 14610620 14657224 15099563 15356132 15546391 15573129 16243976 16413922 17404308 17485448 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21042762 21097505 21115385 21469115 21840487 22077060 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24204259 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8683106 8700208 8837607 9535722 9834059 9845545
PTPN1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 18988627 15780598 15821101 12748279 11694501 11970899 11970898 21806020
JAK2 STAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 9133424
JAK3 STAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 10899310 9133424 16189514
STAM2 MET â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
MET STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
PTPN1 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 18579758 16537444 22789536 18819921
VPS37A MVB12A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37C MVB12A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37D MVB12A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37D MVB12B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37A MVB12B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37C MVB12B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
TSG101 MVB12B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
PTPN1 NTRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 26214522 12237455 25288805
PDGFRB PDGFRA â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFRB PDGFRA â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFRB PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 21071413 2161888 2542288 7523122 1847074 16189514 11331882 10417313
PTPN1 PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 18567737 7545675 7876130 14966296 7693671 19167335 8290276 12614164 12424235 9355745
PTPN1 TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 29145629 23331499 15780598 11694501 16189514 12748279
STAM SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
STAM2 SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
STAM SH3KBP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
STAM2 SH3KBP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
USP8 STAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16520378 10982817 20736164
VPS37D UBAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37B UBAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37C UBAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37A UBAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139