Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
UBE2I ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUMO2 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
E2F3 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18469863 12527885
E2F3 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12527885 18319725
ATM L3MBTL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29581593 31225475
LNX2 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CCT3 LNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
MYC CCT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
CCT5 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT5 STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT8 PFDN2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CEP76 PAICS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DNAJC5 L3MBTL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
L3MBTL2 E2F3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0610279104 17517653
E2F3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11564866 18319725
E2F6 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12004135
SUMO2 ELF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16904644
RB1 HDAC1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
HDAC1 RBPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9694793
UBE2I HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25704882 22493095
RB1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211419 10228159
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
L3MBTL2 HDAC3 â—¼   COLOCALIZATION 2.0 0.8 intact 7719892 20385135
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
HIST1H4A HIST4H4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
KLF3 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18687676
UBE2I L3MBTL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24782567 24369422
SUMO2 L3MBTL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24782567 24369422
LNX2 L3MBTL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
L3MBTL2 MEAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
L3MBTL2 LNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
L3MBTL2 STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
L3MBTL2 PHF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MAX MGA â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
UBE2I MDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
MYC TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11139609
RNF2 PCGF6 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
SUMO2 RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
UBE2I RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RNF8 RNF168 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20385750
SUMO2 RNF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RNF8 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
CCT2 CCT4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RNF2 SCML2 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
WDR5 ZBTB48 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
CCT4 PFDN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CCT5 PFDN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CCT6A PFDN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CCT7 PFDN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
PFDN2 TCP1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
HIST1H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
L3MBTL2 RNF2 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
CBX1 CBX3 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
SUMO2 MDC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 32786267 19471022 22661230 19394292
RYBP TFDP1 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
CCT4 CCT6A â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CCT2 PFDN2 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT3 PFDN2 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT2 TCP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
YAF2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22325352 27705803
BAP1 ELF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 20805357
MYC CBX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CBX1 RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX1 E2F6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX1 EHMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX1 WDR5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX1 MAX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
MDC1 CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22990118 34079125
MYC CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CBX3 TFDP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
RB1 E2F3 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5219804 17380128
HDAC1 RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26496610
HIST1H4A WDR5 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
LIN54 NFYC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 32296183
MYC RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
TFDP1 RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
TFDP1 WDR5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
L3MBTL2 MGA â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ATM MDC1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 12607003
CBX1 EHMT2 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
MAX YAF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 29028833 27705803
YAF2 WDR5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 26186194 27705803 22325352
YAF2 RYBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
MAX CBX3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24981860 29028833 27705803
CBX3 WDR5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33022573 24981860 27705803
MAX E2F6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 25609649 27705803 29028833
MIER2 E2F6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HDAC1 E2F6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
MIER2 EHMT1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HDAC1 EHMT1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
MIER2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
KLF12 EHMT2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 32296183 16189514
EHMT2 KLF3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25416956 35140242 32296183
HDAC1 MIER2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 23752268
MAX RYBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 29028833 27705803
MAX WDR5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20946988 24981860 27705803
MAX RING1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24981860 29028833 27705803
MIER2 TFDP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MIER2 PCGF6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MYC PCGF6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30415952 35140242 29467282
RING1 WDR5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24981860 33022573 22325352 27705803
CBX3 PCGF6 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
COMMD4 TFDP1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
PIAS1 ELK3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 35140242 15580297
HNF4A SUMO2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 35140242 22505616
E2F3 TFDP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ZBTB26 ZBTB48 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
HIST1H3A HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4A HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CCT3 CCT5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CCT8 PFDN5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CCT5 CCT7 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
TADA3 WDR5 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
EHMT2 CBX1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24981860 17962312 19706462 15200951 27705803
MYC HDAC3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18483244 31155734 22002311 23079660
MAX TFDP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 24981860 25609649 27705803 29028833
PCGF6 WDR5 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
CCT5 CCT8 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CCT2 CCT3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HIST1H3A HIST1H4A â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EHMT2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21258344 26028330
WDR5 HDAC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 27705803
HIST4H4 WDR5 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CCT2 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT3 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT4 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT5 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT6A PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT7 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
PFDN5 TCP1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
HDAC1 YY1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
EHMT1 EHMT2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CCT2 CCT7 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CBX3 YAF2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 22325352 12004135 27705803
YAF2 TFDP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22325352 27705803
YAF2 E2F6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 27705803 28514442 22325352
BAP1 CBX3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 29686263 32509391 34591877
PCGF6 CBX1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 24981860 27705803
RYBP CBX3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 34316702 27705803 22325352
CBX3 RING1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 12004135 27705803
CBX3 EHMT1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27705803 34079125
WDR5 E2F6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 15960975 26186194 27705803 28514442
HDAC1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16287849 26496610 23752268 28514442 26028330
PCGF6 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22325352 27705803
HDAC1 TFDP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27705803
HDAC1 WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 22689669 26186194 23752268 27705803 28514442 33022573
MYC HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 17314511 30415952 20195357
PCGF6 HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27705803
MYC WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31767764 35140242 17353931 29467282 30415952 27320920
WDR5 TADA3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 18838386 26186194 27705803 28514442
E2F6 RYBP â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CCT2 CCT8 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
MYC PFDN5 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CCT6A TCP1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
E2F6 PCGF6 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MGA PCGF6 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MGA RYBP â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PIAS1 SUMO2 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
E2F6 RNF2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HIST3H3 HIST4H4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
E2F6 MGA â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
HDAC3 YY1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MGA WDR5 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
E2F6 L3MBTL2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
L3MBTL2 RYBP â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
RING1 RNF2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RNF2 WDR5 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
EHMT1 EHMT2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HDAC2 YY1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
YAF2 RING1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 24981860 25416956 27684187 21516116 27705803 28514442 22325352
MDC1 ATM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29656893 26734725 12607005 14519663 18006705 28943310
CBX3 E2F6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 12004135 27705803 34079125
PCGF6 E2F6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 26186194 27705803 11171983 28514442 16189514 22325352
EHMT2 EHMT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 21258344 28698370 21430779 27705803 34588438 26028330
L3MBTL2 PCGF6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
NFYC MYC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10446203 11282029
RING1 PCGF6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12167161 33961781 32296183 24981860 27705803 28514442 22493164 22325352
PFDN2 PFDN5 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CCT6A CCT7 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CCT6A CCT8 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
ATM TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15838517 15494392 15140942
EHMT2 CBX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 17962312 22514736 15200951 27705803 34079125
MYC CBX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CCT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
RYBP E2F6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 12411495 26186194 27705803 11171983 28514442 16189514 22325352
MYC GAS8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HDAC1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18634613 11486036 11940654
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
RNF8 MDC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24240613 25512560 18001825 26734725 18001824 18006705 28943310
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
RBPJ MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18490439 10644343 16847353
MYC SMARCAD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC ZFP36 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
SUMO2 PIAS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22578841 19471022 19394292 20016603 16524884 21252943 18806873 19217413 21693764
CCT3 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT2 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT4 CCT8 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
E2F3 RB1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CCT3 CCT4 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT5 CCT6A â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
PCGF6 RING1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
LHX4 YY1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PCGF6 RNF2 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
RNF2 YAF2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
RING1 YAF2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
CCT4 TCP1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
HDAC1 RB1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CCT4 CCT7 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
E2F6 TFDP1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CCT7 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT8 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
RING1 RYBP â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CCT3 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT3 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
CCT7 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
CBX1 HIST3H3 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TFDP1 E2F6 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
RB1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 6550000 10779361
CCT2 CCT5 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
CCT3 CCT7 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
CBX3 EHMT2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
E2F6 RING1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 11171983 24981860 27705803
RYBP RNF2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
PIAS1 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CBX3 HIST1H3A â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CBX1 HIST1H3A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
RYBP RING1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 32296183 17070805 24981860 16943429 30217970 34316702 10369680 26186194 27705803 25416956 34133714 16189514 22325352
CBX3 HIST3H3 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
RB1 TFDP1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HIST3H3 WDR5 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
HIST1H3A WDR5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT3 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A TCP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SUMO2 UBE2I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT5 CCT6A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT8 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT4 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MAX MYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RNF2 RYBP â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ATM MDC1 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM MDC1 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM MDC1 â—¼   ENZYMATIC_REACTION ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM MDC1 â—¼   REGULATES ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 28193847 21705321 22234877 12607003 12607005 22234878 17525332 18006705
E2F3 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19015245 9711036 24287699 16449662
RB1 E2F3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17380128 8657117 17488475 10779361 7739537 8832394
E2F3 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8755520 7739537 8657117 8832394
UBE2I HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
UBE2I HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12820959 15340381 11960997
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
HDAC3 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC2 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9016636 19139378 11486036 8917507
HDAC3 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11486036 9346952 17925399 16189514 18940814
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
IRF1 MYC â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10485906 10820262 11399519 11875494 12417340 12433365 15644117 16127449 16597464 17260466 17689680 18345002 21097505 22461508 23390297 6357187 8871614
PIAS1 KLF8 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 15117942 16127449 19218564 20711444
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
MYC MAX â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MAX â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508165 15665468 8385351 8649388 8521822 22384171 1406956 17341548
MAX MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 17145710 16287840 25609649 12821782 16606833 16596619 21807113 25522242 20691906 19578763 24951594 8224841 17643117 9528857 12391307 16705173 21150319 10229200 21988832 15572685 9680483 2006410 17314511 14749374 12553908 17289033 17418410 19623651 12824180 17157259 12584560 26496610 20946988 20936779 8425218 23816886 17353931 10319872 17471507 18003922 16140957 20382893 12660246 8266081 7565735 32296183 10465786 26267534 17072308 27705803 9184233 18620061 10918583 17700062 10593926 10611234 16352593 9708738
MAX MGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21988832 20936779 25609649 27705803 7954804
MDC1 RNF8 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 12607003 15279786 15459660 15496928 15549137 15655342 17303408 17660363 18001824 18001825 18006705 18087291 18171670 18212739 18583988 18590585 18678709 18678890 18809224 19217833 19270065 19490890 19772495 20021983 20064462 7575488 9407949
MDC1 RNF8 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12607003 15279786 15459660 15496928 15549137 15655342 17303408 17660363 18001824 18001825 18006705 18087291 18171670 18212739 18583988 18590585 18678709 18678890 18809224 19217833 19270065 19490890 19772495 20021983 20064462 7575488 9407949
MDC1 RNF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 24240613 18001824 25512560 18001825 18678647 18082599 18006705
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
UBE2I MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11779867 16713569 22910413
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
MYC PAICS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
MYC NFYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11282029 10446203
RB1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12588874 11118439
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368