Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16249378
BCL6 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15577913
H4C6 CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CBX5 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19834512 7297014
CBX5 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YY1 CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19566924
ATP6V1B1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KLF3 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SETDB1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KDM1A EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
RELA KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19208907 23423566
MDM2 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 23839035
EZH2 MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19749796 23349306
SIRT6 ELF5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 TFDP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574328 24096481
TP53 COX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MAX TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7969121 10348347
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
TP53 IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11672436 18056423
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
TP53 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
H4C6 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YY1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12039077 10030686
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
ATXN1 ATP5F1D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NR3C1 KLF15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20956975 23508109
ADIPOQ HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CREB1 ADIPOQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23568554 19932681
NFIA MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32991581
RELA ZEB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23584475 16862183
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
HDAC1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10220385
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
HDAC2 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
MAX MGA â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
KLF8 CTBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17671186 19798104
KLF8 CTBP2 â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 17671186 19798104
KLF3 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18687676
RELA DNMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23457487 24025864
ETV3 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18025162
NFKB1 CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15459115
NFKB1 HIF1AN â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 17003112 0606877103
HTT CREB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CREB1 ALAS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11139395 10600163
CREB1 ETV3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14754893
H3C2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF12 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H4C6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H3C14 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT ATP5F1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CBS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 ATP6V1B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H4C6 DNMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 CA12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18451179 18414489
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
EED H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EED H3C2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EED H3-3B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EED H4C6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
RNF2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF3 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AK2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ADCY6 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
H4C6 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3-3B EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EZH2 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
HNF4A CYP2C19 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20086032 16540586
RNF2 PCGF6 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
KLF12 EHMT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LCOR EHMT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EHMT2 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EHMT2 XAGE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ZNF516 CTBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 28947780
CTBP1 ZNF516 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 28947780
YAF2 RING1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 8153045 21516116
JARID2 EHMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19010785
MYB PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9371644 7838532
MYB NFIB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20647765 19841262
NFIC ALAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15123725
NFIC CYP2A6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17148654 15123731
NFIB NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
NFIA NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
NFIA CYP2A6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15123731 11741324
DBH H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATP5F1E ATP5F1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CA12 ATP5F1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
HIST1H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
CHD4 EZH2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
L3MBTL2 RNF2 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
CTBP1 ZEB1 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
CBX3 TFDP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
DNMT1 CBX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17470536 12867029
CBX5 WIZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 20562864
CBX5 EHMT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 20562864
SOX2 KDM1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30442713 28794006
YAF2 MDM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TFDP1 WDR5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
HDAC2 ZBTB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26949739 33301849
HDAC1 RING1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26496610
HDAC1 WIZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
YAF2 HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22325352 27705803
KLF8 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21416054 35140242
ESR1 CTBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
CTBP1 EZH2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31041561 27634302
EZH2 EHMT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 26496610
EHMT2 ZNF644 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
REST EHMT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17468742 15200951
SOX2 TEAD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
TFDP1 RING1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
H3F3A WDR5 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
DNMT3A H3F3A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
L3MBTL2 MGA â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
DNMT3A HIST3H3 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
CHD4 H3F3A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
H3F3A SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
MAX CBX3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29028833 24981860 27705803
CBX3 WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 33022573 27705803
ESR1 KDM1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23403292 17289570 31527615
KDM1A EZH2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31130994 23455924
MAX WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 27705803 20946988
YAF2 WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27705803 22325352 33961781 24981860 26186194
RING1 WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 24981860 33022573 27705803
WDR5 SOX2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30089852 35140242 29383478
HDAC1 ZBTB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 33301849 26496610 33961781
HDAC1 RREB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 33961781 26496610
HDAC1 MIER2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 33961781 26186194
HDAC1 E2F6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
HDAC1 EHMT1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
MAX RING1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29028833 24981860 27705803
MAX E2F6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27705803 33961781 25609649 24981860 29028833
MAX PCGF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27705803 22325352 33961781 25609649 24981860 29028833 20946988
MAX YAF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29028833 33961781 27705803
EZH2 CHD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28486105 28068325 24981860 26344197
EHMT2 CHD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28486105 26028330 32744500
CTBP1 CHD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31041561 24981860
E2F6 EZH2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16565076 15536069
MIER2 EHMT2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
KLF12 EHMT2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 16189514 35140242
EHMT2 CTBP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 17967884 31041561 16702210 33961781 26186194
EHMT2 KLF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 35140242
WIZ CTBP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 17967884 31041561 16702210 33961781 35016035 26186194
CTBP1 KLF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27107012 35140242 24722188
CTBP1 RREB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 17967884 33961781 35016035 26186194
CTBP1 RCOR3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31041561 33961781 26186194
MIER2 PCGF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MIER2 E2F6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MIER2 EHMT1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MIER2 WIZ â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SOX2 NFIB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 21532573 28794006
MIER2 TFDP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CBX5 EHMT2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
CBX3 H3F3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 H3F3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX3 PCGF6 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RCOR1 REST â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CTBP1 ZEB2 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
NR3C1 RELA â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
ESR1 IGF1R â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10749889 24051437 14764897 28555617 16113100
ESR1 EHMT2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21984853 31527615
ESR1 EZH2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
EHMT1 CTBP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 31041561 16702210 33961781 26186194 12700765
HIST3H3 MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
H3F3A MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MEN1 WDR5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
CDYL HDAC2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
DNMT1 HDAC2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
H3C2 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 20871592 8087215
CBX5 H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 16415788 5218238
H3C2 CBX5 â—¼   PROXIMITY ✅ 0.85 0.85 mint 25281560
CTBP1 ELK3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 35140242 16189514 16713569 10369679
MAX TFDP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27705803 33961781 25609649 24981860 29028833
DNMT1 EZH2 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
KLF12 CTBP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25416956 11373277 35140242 24722188 27107012
PCGF6 WDR5 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
H3F3A HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
HIST3H3 SETDB1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
CBX5 EHMT2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24981860 17962312 20562864 15200951
KLF3 KDM1A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 23455924
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
WDR5 HDAC2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 27705803
MIER1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 6613464 18451879
EHMT2 HDAC2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21258344 26028330
HDAC2 RREB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23752268 21258344
SOX2 EHMT2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
EHMT2 MIER1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21258344 18451879
SOX2 MIER1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
HDAC1 NR3C1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
HDAC1 YY1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CBX4 RNF2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CHD4 HIST3H3 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CBX3 EHMT1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 27705803
CBX3 YAF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22325352 27705803 24981860 12004135
CBX3 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 33961781 21888893 24981860 28977666
CBX3 WIZ â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 27705803
CBX3 RING1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 33961781 12004135 24981860
CBX5 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32744500 27705803 24981860 15882967 28977666
EHMT2 KDM1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26028330 26751641
KDM1A RREB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 23752268 16140033
KDM1A CTBP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 17967884 31041561 28947780 20547759 26496610 33961781 26186194 16140033 16079794
RCOR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 17967884 19242095 31041561 28947780 33961781 26186194
PCGF6 WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860 26186194
HDAC1 WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 27705803 33961781 26186194 33022573 22689669
WDR5 E2F6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15960975 28514442 27705803 33961781 24981860 26186194
ZEB2 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34026424 18182442 26028330
PCGF6 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22325352 33961781 27705803
HDAC1 REST â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18806873 10491605
HDAC1 EHMT2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 26028330 26496610 33961781 16287849
HDAC1 TFDP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803
HDAC1 RCOR3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 26496610 21258344 33961781
PCGF6 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803
EZH2 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10581039 24981860 21685935 26344197
HDAC2 MIER2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 30737378 21258344 33961781 26186194
LCOR EED â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 26496610 27705803
LCOR EZH2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 26496610 27705803
CBX4 PCGF6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21282530 33961781 27705803
PCGF6 TFDP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
PCGF6 YAF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
YAF2 E2F6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
NFIB NFIA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 35140242 33961781 26871637
YAF2 TFDP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22325352 33961781 27705803
CBX3 CBX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CBX4 CTBP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
KDM1A ZNF217 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CTBP1 ZNF217 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
E2F6 PCGF6 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MGA PCGF6 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CDK7 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15461668 10949034 31527615
IGF1R MDM2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 12821780 20195357 28092675 18632619 19165858
MDM2 CTBP2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12867035 21057548
ZEB2 CTBP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31041561 33961781 12714599 26186194 24722188 16061479 35016035
ZEB2 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34026424 18182442 26028330
HDAC1 CHD4 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 26949739
CTBP2 LCOR â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CBX4 CTBP2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 16189514 9858600
DNMT1 EED â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16357870 22094255
WIZ EHMT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26344197 16702210 26496610 24981860
RCOR1 ZNF217 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
E2F6 RNF2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
EHMT2 WIZ â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
IGF1R MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MGA WDR5 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTBP1 CTBP2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
E2F6 MGA â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
E2F6 L3MBTL2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
HDAC2 RELA â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
RNF2 WDR5 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RING1 RNF2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CTBP1 KDM1A â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HDAC1 BCL6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15454082 9627120 9753732 16147992 10611298
CBX3 PCGF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27705803 12004135 22325352 33961781 24981860
CBX3 E2F6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27705803 12004135 33961781 24981860 34079125
HDAC1 KDM1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16079794 19703393 21258344 34050636 11102443 27183383 16140033 21937684 12032298 26496610 22143567 19497860 11171972 17634443 12493763 20856864 20585571 31130994 21670149 26344197 23752268 32882276 17687328 33961781 24981860 28667074
MDM2 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12897156 11178989 16713569 10766163 17545634 31012223
MEN1 WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15960975 27705803 23508102 24981860 14992727 15199122
HDAC2 YY1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
HDAC1 MYOD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11285237 11684023 16713569 20124407
EED HDAC2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
HDAC2 CTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17967884 31041561 16713569 28947780 16036112 10766745 18212045 11022042
HDAC2 RCOR3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23752268 21258344 24981860 26949739
HDAC2 DNMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23708667 17967891 21670149 10888872
HDAC2 MIER1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23752268 19293945 30737378 21258344 18451879
CTBP2 LCOR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 25416956 27705803 12535528 33961781
CTBP2 CTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31041561 16189514 25416956 16713569 21988832 28947780 30585266 26496610 33961781 35016035 26186194 24722188 27107012 9858600 26344197
DNMT1 EZH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31130994 16357870 22094255 28068325 21378168
EHMT1 EHMT2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
WIZ EHMT2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16702210 26028330 27705803 26496610 21258344 24981860 28698370
EHMT2 EHMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21430779 26028330 27705803 21258344 24981860 34588438 28698370
CTBP1 LCOR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31041561 20211142 12535528 27705803 33961781 35016035 26186194 24722188
YAF2 RING1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 25416956 27705803 22325352 33961781 24981860 21516116 27684187
RING1 PCGF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 22493164 12167161 27705803 22325352 33961781 24981860
PCGF6 E2F6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16189514 11171983 27705803 22325352 33961781 24981860 26186194
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
L3MBTL2 PCGF6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HIST1H3A KDM1A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HDAC1 MIER1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
EZH2 HDAC2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
TP53 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23852341 19427386
CBX5 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314413 11336697 16713569 20850016 27705803 20231385 33961781 21888893 24981860 15306854 34079125 20562864 19498464
EHMT2 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27705803 22514736 33961781 24981860 15200951 34079125 17962312
CBX5 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19834512 17403666 19111658
RCOR1 KDM1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19703393 21258344 34050636 11102443 18806873 16140033 12032298 22143567 20389281 11171972 21300290 16885027 21602794 26226427 21142040 21670149 26344197 24217620 32882276 20164337 28667074 17687328 33961781 27173435 24981860 34079125 34031383 16956976 16079794
KDM1A RCOR3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 21258344 23455924 24981860 34079125 26344197
KDM1A HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 32882276 19703393 9804427 12032298 20164337 28667074 26949739 34031383 21258344 26344197 34050636 21670149 24981860 11102443 12493763 16079794 21937684
HDAC1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15640443 33985974 12426395 30818224
NFKB1 MEN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11526476 16651450 16713569
RCOR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 17939992 19703393 12032298 26496610 17938259 21258344 33961781 15897453 19497860 12192000 11602581 11171972 17956988 18806873 11102443
RCOR1 HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 12032298 30737378 26949739 21258344 33961781 24981860 12192000 11171972 11102443
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
TP53 MGA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
YY1 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9199306 7494244 12296377
HDAC1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18634613 11486036 11940654
ADIPOQ ADIPOR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 26578976 12878598 12802337
MIER1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 16189514 26496610 21258344 33961781 12482978 18451879
CTBP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 9650586 16189514 23752268 31041561 16713569 28947780 10995736 34147029 18765668 11022042
CHD4 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25247294 32744500 21258344 11102443 28977666 9885572 26496610 20585571 10220385 22075476 21670149 22939629 23752268 27616479 9790534 9804427 26949739 20693977 33961781 24981860 12920132 26344197
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
HDAC2 CHD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 9790534 9804427 11003653 22939629 30737378 28977666 26949739 32744500 21258344 24981860 21670149 12493763 9885572 10545197 26344197
CTBP2 KLF8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 35140242 10756197
NR3C1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12734399 9261164 9442377
MYB IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10465027 19427836 23675407
KLF3 CTBP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9724649 35140242 32296183 12556451
CREB1 DBH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8753872 9763470 9341190
DNMT1 CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21392518 20082704 20214950
ESR1 CYP2B6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20079471 18414489 22484313
ESR1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15358113 15499176 18299335
ESR1 CYP2C19 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20675569
ESR1 NFIB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26153859 18414489
NR3C1 IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23161582 9369450 18483179
NR3C1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17978169 24399729
CBX4 CTBP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15592428 20098713 33961781 20361981 12679040 26186194 11583618 9858600 12829790
CBX4 RING1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282530 16189514 9858531 22078878 9199346 26496610 27705803 22325352 24981860 30317550
E2F6 TFDP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16189514 25416956 9501179 20211142 9704927 27705803 33961781 24981860 26186194 26871637 15536069
NFIC NFIB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 9099724 35140242 33961781 25258084
NFIB NFIX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9099724 35140242 33961781 26871637
NFIB NFIX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9099724
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
HIST1H3A SETDB1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
EZH2 EED â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
HDAC2 RCOR1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
EED HDAC1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
LHX4 YY1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PCGF6 RING1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
PCGF6 RNF2 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
RNF2 YAF2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
RING1 YAF2 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
MDM2 USP7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ATP6V0A1 ATP6V0C â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CBX4 RING1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
DNMT3A MPHOSPH8 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ATP6V0C ATP6V0D2 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ATP6V0A1 ATP6V1B1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
HDAC1 RCOR1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
E2F6 TFDP1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CHD4 HDAC2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
EZH2 JARID2 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
DNMT3A HIST1H3A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
CHD4 HDAC1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ATP6V1B1 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
CTBP2 ZEB1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 9724649 16713569 34462429 25086746 12714599 10567582 19754958 10359772
TFDP1 E2F6 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
CBX3 EHMT2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CBX5 HIST1H3A â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CTBP1 ZEB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 17967884 31041561 34462429 25086746 33961781 10567582 26186194 35016035 10359772
EZH2 HDAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 21685935 15520282 10581039 24771265 31130994 22439931 26344197
E2F6 RING1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11171983 24981860 27705803
HDAC2 KDM1A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
CHD4 HIST1H3A â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
CBX3 HIST1H3A â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
USP7 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6799761 18566590
RCOR1 REST â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10449787 17939992 15897453 25197063
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
EED HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10581039 11124122 26496610 22439931
HDAC1 DNMT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22274925 20613874 26794444 10615135 10888886 17707923 17934516 15870198 21670149 27593931 17967891 12473678 23708667
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
EED HDAC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30737378 10581039 11124122 24981860 24457600
EED EZH2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21135039 9584197 9742080 31948940 29379173 27338022 18931660 28068325 33754075 11158321 9584199 32296183 22897849 17937919 19026780 21190999 26496610 24320048 33849069 27634302 15385962 16314526 29669287 15225548 18285464 10581039 21123648 12435631 31786184 23624935 24457600 20075857 15882624 19026781 21078963 22094255 22439931 28320739 27705803 31527584 24981860 33961781 23280602 26344197
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
CBX3 HIST3H3 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
DNMT1 USP7 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
HIST3H3 WDR5 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CBX5 HIST3H3 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
HIST1H3A WDR5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
KDM1A RCOR3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
EED JARID2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
KDM1A RCOR1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBX3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15136563 20871592 20011120 24576085 19111658 16415788 26527279
E2F6 CBX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18319725 12909625
CBX5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16687578 16622419 20871592 20011120 25281560 26527279 19111658 16415788 19498464
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
CDK7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17591690 11709713 12064478 1088347 16083285 9372954 11483158 9620776 10348343 10884347 16552184 9315650 11007451 9571186 10747897 17898864 1454855 11585729
KDM1A H3-3B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
KDM1A H3C2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
KDM1A H4C6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
KDM1A H3C14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
KDM1A ESR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
RCOR1 KDM1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 21300290 18806873 24217620 11102443 21258344 20389281 11171972 21142040 21670149 19703393 17537733 21602794 16885027 26226427 12032298 20164337 17218267 16140033 22143567 17687328 16956976 16079794
KDM1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17805299 26334721 19381457
KDM1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16223729 20210320 18343668 20228790 15620353
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
USP7 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 17936559 26460617 15916963 24462112 22056774 18566590 20816748 16402859 20713061 16943424 17380154 29236775 16082221 26238070 34799561 16845383 16474402 28406480 27452404 28196907
AKT3 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
AKT2 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 11504915 17646672 10217147
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MDM2 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 25241761 28092675 12821780 18632619 17303558 19165858 36042202 20195357
MEN1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11526476 14508515 16713569
MEN1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11526476 16997566 16713569
RCOR1 REST â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19394292 10449787
SIRT6 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18337721 16439206 19408108
SIRT6 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19408108 19135889
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
YY1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10787423 10634504 8816507 10505791 18391986
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
NFIA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12145335 10505791 10634504 8816507
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11818510 16895524
TP53 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15131018 11001824 12089352 20633551 24205274 17097318 10023442 17600529 17014845 8710868 12444079 16181796 22033326
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
NFKB1 YY1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17438126 21725609 23178297 23572150
HDAC2 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9016636 19139378 11486036 8917507
ADIPOR1 APPL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16622416 23762377
ADIPOQ ADIPOR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21284979 12802337 16622416
CTBP1 ELK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10369679 14693367 16713569
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
ZEB1 SOX2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
CTBP1 ZEB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24722188 26186194 12714599 16061479
ZEB2 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24722188 26186194 12714599 12743039 16061479
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
NR3C1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15826950 16762839 18762022 18028994
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC2 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
MAX MGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21988832 20936779 25609649 27705803 7954804
KLF8 CTBP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10756197 16713569
CREB1 RELA â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CREB1 RELA â—¼   PROTEIN_INTERACTION 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
CREB1 RELA â—¼   DOWN_REGULATES ✅ - 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
RELA CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19002106 16608838
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
NR3C1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
RELA NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
NR3C1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8639160 17016446
NR3C1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 8290595 16380507 7823959
CREB1 CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15955695 23846817 21212407 17596931 9365194 19679653 12846424 16740737 23566437 11850205
AKT2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
NR3C1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20203101 16713569 8449898 7621901
AKT3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
CAMK4 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 11175347 12356771 15733869 11160957 8195196 7958915 9829964 12235136 9687510 7864890 8887554 11698596 11970865 8688081 17389598 9528766 12835716 11018520 11969286 11909979
AKT3 CREB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
DNMT1 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT1 H3-3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT1 H3C2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT1 H3C14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21655924 20946668 17172825 15746193 22975348 12789259 19001520 24058781 23242655 22558281
ZNF217 ESR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
ESR1 CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19462000 20351196 19605792 11973645 16885386 19282383 19250199 12839940
AKT2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11139588 11432835 11507039 9528769 7838153
EED EZH2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
H4C6 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C2 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C14 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
EHMT2 DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19308066
EZH2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18022353 15196462
HNF4A AKR1C4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11284743 12220531 2044952
HNF4A CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19077665 20926756 21952236 14742674 17764444 15698577 17344340 12514743 16455805 19934400
HNF4A CYP2B6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19467232 16540586 18666237 8751713
MYB NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16263717 15044598 22516378
NR3C1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18805405 7499421 17572486 10772626 11602528
NR3C1 CYP2B6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14683479 11093784 12695351 19702527
EHMT2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19690169 17194708 22387026
EHMT1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20084102 19010785 20118233
ASH1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17923682 21239497 20068231
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
NFIB NFIC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9099724 25258084 16189514
SETDB1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21243721 11791185 11252719 11959841
ZNF217 H4C6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
ZNF217 H3-3B â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
ZNF217 H3C2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
ZNF217 H3C14 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799