Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
JUN JUND â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8922393 2504580
TEAD1 CS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7775450 9259315
ATXN1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JUN AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 11192249
CUX1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14612449 22422878
RUNX3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24042352 22231444
FOXO3 AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 10102273 5211323
CIC ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HIVEP1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RNF2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMARCD1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZNF609 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ZHX2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RYBP ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BCOR RNF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 17296600
JUN BMP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11044605 21898398
CTCF CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18625744
TEAD1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20153295 22286761
NCOA1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21163886 22542550
EHMT1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19010785
CHD3 RAD51 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NCOR2 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12589049 10612426
YY1 CTCF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9756895
EGR2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2115122 1427072
TEAD4 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19285023 22433836
SRF FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15806162
RCOR3 GSE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KDM2B JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17704768
TCF7L2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
TBP JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17074809 21106530
MEF2C JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9384584
KDM2B RNF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 17296600
YY1 KDM6A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
RYBP LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAX MGA â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
TEAD1 MYF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20153295 21527258
TEAD1 MYH7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8253797 10998641
POU2F1 TEAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220828 8423815
TEAD1 RUNX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10228168 26364597
YAP1 RUNX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10228168 26364597
RUNX3 TEAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10228168 26364597
SMC3 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TEAD1 TBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220828 8423815
WWTR1 TEAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
YAP1 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213829 11278685
TCF7L2 TLE3 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
EHMT1 WIZ â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CREBBP FGFR1 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
RYBP TFDP1 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
PBRM1 SMARCA2 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
EHMT2 ZNF644 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
SKP2 AKT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19270694 23911321 19270695 21358672
JUN CHD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 21196933
FOXK2 CIC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 29844126
CIC NFIC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29844126 35140242
CIC TEAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29844126 35140242
CIC NFIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29844126 35140242
CIC NFIA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29844126 35140242
SMC1A CTCF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33196849 18219272
FOXK2 TEAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 26344197
TEAD1 JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 26258633
TLE3 MYH7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TFAP4 NFIC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 19505873
TFDP1 RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
SOX2 SALL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
SOX2 TEAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
TEAD2 TEAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SMARCD1 SMARCD3 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
ARID1B SMARCD3 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
CREBBP FOXO3 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
WWTR1 TEAD2 â—¼   PHYSICAL_INTERACTION ✅ + 0.82 0.82 Signor 23431053
BCL7C PHF10 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
BCL7C ARID2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 18809673 24981860
JUN JUND â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649
BRD7 ARID2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24657164 24981860 26344197 30940648 18809673
FOXK2 ASXL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24748658 26416890 32669118 25609649 27705803
SOX2 KDM6A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22801502 35140242 28794006
LMNA PIAS2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 24623722 34079125
MAX RYBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 29028833 27705803
MAX RING1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24981860 29028833 27705803
SOX2 NCOR2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 28794006 21532573
SOX2 NFIB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 28794006 21532573
TEAD1 RAD51 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TEAD4 TEAD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TEAD4 TEAD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZKSCAN4 ZSCAN21 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
BPTF TFAP4 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ARID2 BRD7 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
AKT1 SKP2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
BCL7C BRD7 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
IRF2BP2 VGLL4 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
TEAD4 VGLL4 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
ARID2 BCL7C â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CBX2 RING1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
MAX TFDP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 24981860 25609649 27705803 29028833
NCOA1 TBP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8754792 16713569
VGLL4 TEAD4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 24525233 26186194 28514442 31559693
SOX2 CHD3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23667531 28794006
SOX2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
FOXC1 NFIC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 35140242
SOX2 FOXK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
FOXK2 NCOR2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 27773593
SOX2 ZFHX4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
EHMT1 EHMT2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
POU2F1 SOX2 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
ARID1A PHF10 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
PHF10 SMARCA2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
ARID1A BCL7C â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BCL7C DPF2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ARID1A ARID1B â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SOX2 CHD7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 28794006 23667531 21532573
DACH1 JUN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16980615 17182846 25609649
SOX2 FOXC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
FOXK2 TFAP4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25609649 28514442 33961781
FOXK2 TBL1X â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25609649 27773593
NFIB NFIA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26871637 35140242
SOX2 SMC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
WWTR1 TEAD1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 32296183 25796446 26186194 28514442
ARID1B BCL7C â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BRD7 PBRM1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BCOR KDM2B â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BCL7C SMARCD1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BCL7C SMARCA2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TEAD1 TEAD4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
DPF2 SMARCD2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
DPF2 SMARCD3 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MGA RYBP â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BCL7C SMARCD2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BCOR RING1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BPTF MAZ â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10727212 15379550
WIZ EHMT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24981860 26496610 16702210 26344197
EHMT2 WIZ â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
RING1 KDM2B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24981860 27705803
TEAD1 MEF2C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12861002 12061776
SMARCD1 SMARCD2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BCL7C SMARCD3 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
BCOR RNF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TEAD1 VGLL4 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
SSBP2 SSBP3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
RING1 RNF2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ARID1B DPF2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
ARID2 BRD7 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
DPF2 SMARCA2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
BRD7 SMARCD1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CREBBP JUN â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
BCOR RYBP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EHMT1 EHMT2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
TEAD4 WWTR1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
FOSL1 JUND â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26258633 24029232
EHMT2 EHMT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 21258344 28698370 21430779 27705803 34588438 26028330
WIZ EHMT2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 21258344 28698370 26496610 16702210 27705803 26028330
NCOA1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10567404 10847592 9642216 16713569
TBP JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7685215 7848298 16055710 16713569
RYBP KDM2B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 34316702 26186194 27705803 23395003 28514442 22325352
SRF TEAD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11136726 12061776
FBRSL1 RYBP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
TEAD1 WWTR1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
KDM6A KMT2C â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CCND1 TFDP1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
FOXM1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23812424 19097132 11572993
SOX2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18456656 25482558
FOXO3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12391153 21294163
YY1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9238849 21852380
FGFR1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25241761 15929978
TEAD1 CSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8621623 7775450 10727247
SOX10 EGR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22492709 19922439 12538520
SOX10 EGR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16582099 16311519
TBP FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22848139 7667110 1538403
FOXO3 RUNX3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16373335 16738314 12637528
TEAD1 MSLN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17909009
NFIC NFIB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 35140242 9099724 25258084 28514442 16189514
VGLL4 TEAD1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 35140242 26186194 15140898 28514442
YAP1 TEAD1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 11358867 29891922 32220262 25751140 26933062 24255178 22863277 30417565 31619268 31496812 30640473 24882516 24581491 28514442 25751139 25796446 27886176 26258633
YAP1 TEAD2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25751139 35140242 32296183 26578655 11358867 20368466 28205554 28628118 28514442 25973055
TP63 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278685 35044719
FOSL1 JUN â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PHF10 SMARCD1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
KDM2B RNF2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
ARID1A SMARCD3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
KDM2B RYBP â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ARID1A SMARCD2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
ARID2 SMARCD1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
KDM6A KMT2D â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
SMC1A SMC3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
KDM6A PAXIP1 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
CBX2 RNF2 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ARID1B SMARCD1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
RING1 RYBP â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
AKT1 FOXO3 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
ARID2 SMARCA2 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
ARID1B SMARCA2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
CBX2 RYBP â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10369680 24981860
ARID2 PBRM1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
TEAD4 VGLL1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ARID1A SMARCA2 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
SMARCA2 SMARCD2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
SMARCA2 SMARCD3 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
RYBP RNF2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
NCOR2 TBL1X â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PBRM1 SMARCD1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
TEAD2 YAP1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
NIPBL SMC1A â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
SMARCA2 SMARCD1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
JUN FOSL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11912197 33961781 11431474 11708771 23661758 9160889 24029232 20511396 26258633
RYBP RING1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 32296183 17070805 24981860 16943429 30217970 34316702 10369680 26186194 27705803 25416956 34133714 16189514 22325352
SMC3 SMC1A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 22939629 26496610 31807710 30021884 21880767 17112726 10931856 26344197 11590136 12759374 17349791 9789013 23242214 11877376 18832153 27173435 31010829 11076961 22885700 21111234 17113138
YAP1 TEAD4 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25751139 32537835 11358867 25796446 24525233 33571521 25751140 29091762 26186194 30472188 28514442 31559693 26592798
CREBBP NCOA1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ATXN1 CIC â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
DPF2 SMARCD1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ARID1A DPF2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ARID1A SMARCD1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NIPBL SMC3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
TEAD4 YAP1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
TEAD1 YAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RNF2 RYBP â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMC1A SMC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SRF MEF2D â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 21057636 7923378 16484497 15880109 29559111 19116276 19193899 9390517
MEF2D JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9252389 7760790 12054430
JUND FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23319049 13679379
JUND CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10760799 19828633
JUND IVL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11254751 17882273 7759510 17205062 10816578
JUN IVL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15586248 22649503 16374477 15790882 9424084 9506439 17882273 15025563 7759510 20006635 17205062 21966511 15037572
FOSL1 IVL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15790882 11254751 17882273 7759510 17205062 10816578
FOXO3 AKT1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
AKT1 FOXO3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
FOXO3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19424579 23517348 21752881 22539004 11278373
AKT1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 27979972 25360797 26804165 28273460 25751140 24101154 25751139 34052254 25362852 28114269 28793266 26265440 31239271 25601544 28474680 33630828 26119935 27144834 27425596 25531778 34206989 34465890 21945154 25195862 31792377 18640976 28775168 32015438 32523092 22234184 33536280 33622361 30600590 24362629 34155345 24658687 21060948 33162394 20153295 26668327 21730131 26549256 21666719 25605730 26039999 34226698 20823509 34516278 27033705 32064037 32271880 32513743 33990468 24812269 32053631 32929029 34058200 25772246 26364602 27765911 26678338 27979971 33552953 28171658 34129887 21376238 28416665 25998128 25109332 12535517 31988076 26933062 26598551 25373897
AKT1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 19951971 11756412 11953455 11923280 20452955 21798082 20398329 21329882 10217147 11154281 11994454 23331499 10995739 19216069 20214616 11463845 21775285 20068231 9829964 17570479 10102273 18593906 17646672 16680151 18988627 21621563 15169778 17522590 25241761 23109003 11715018 19188143 15023346 17680028 26192618 11864996
AKT1 ATXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15757972 15824120 17540008 34302818 24903464 29212253 33709453 12741986 17570479 21722762 29758256 23719381 20037628 23213356 12757707 24858692 20477910
AKT1 SKI â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19875456
AKT1 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23807222 28446188 22733130 19270695 20160512 19549334 21963805
JUN CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11413310 10760799 19828633 10075858 20862675 26096887 7513046
JUN CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16393119 21135252 8917510 17166846 19622016 11402335 20220142 22853846 17670745 10567390 17496887 19499154 9878062 21474819 17278098 15282324 15467760 15994313 14672732 15574422 22550166 10066798 17637753 20482821 15574764 11745411 11410592 18084253 20037604 12794082 10790372 16860316 24190040 17501623 17477349 19435822 10500157 11432833
POU2F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14645506 12391146 15282324 15885880
TCF7L2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17108104 17360646 17468517 15026412 12235165 15126340 22005519 22318732
FOXM1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16585184 11572993 10567581 11391529
JUN CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
MAX CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
TCF7L2 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
CCND1 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9190208 10498883 9315635 10385618 10778858 9736735 7736585 9425340 11520855
CREBBP TCF7L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
NCOA1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10777539 15671023 12748280 11463834 14966289 19194461 9792627 18193094 11747826 17400812 17244199 9223281 10594042
CREBBP JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8028671 10327051 2138276 9659924 9786917 16713569 17296604 8545107 18443043 16055710
EGR2 SOX10 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16136673 25974668 11734543 8842374
EGR2 WWTR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
EGR2 TEAD1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
JUN FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18435914 15806162 13679379 17082637
JUN FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9160889 11708771 23661758 20511396 11431474 24029232 11912197
FOXM1 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16585184 16314512
MEF2C JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9069290 9252389 10523670 11158308 7760790 10849446 12054430
MAX MGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21988832 20936779 25609649 27705803 7954804
NFIB NFIC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9099724 25258084 16189514
TEAD1 SOX10 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
YAP1 SOX10 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
SOX10 WWTR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
ZEB1 SOX2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
TLE1 TCF7L2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10485845 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
TLE3 TCF7L2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10485845 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
YAP1 TEAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22863277 11358867 25751140 30417565 24882516 26258633 23431053 24581491
YAP1 TEAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 25973055 26578655 11358867 25751139 20368466 23431053 35140242
WWTR1 TEAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 31515488 16189514 32296183 23431053 20972459
YAP1 TEAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24525233 25751140 11358867 25751139 26592798 23431053 32537835
TLE1 TLE3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10485845 11934263 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
YAP1 WWTR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338