Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ATM EYA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19234442 19351884
HMGA2 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21339738
ATM HMGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21339738
BCL2L1 BAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
BCL2L1 BAK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
ETV4 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18510939 15466854
IRF8 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21949018 23677993
NR4A3 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30455429
FOXO1 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15817464 15632117
FOS BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16911523
FOXO1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15059979 10871843
IRF8 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10430629 23677993
FUS BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18471544
GOLGA2 BCL6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
BCL6 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
BCL6 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11920165 11341761
BCL6 IRF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10601358
TP53 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16249378
BCL6 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15577913
CDKN1A DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19541625 0812254106
KLF5 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19628677 21383775
NFIA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17130157
SOX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
HNF4A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17885207
SRF CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20068148 16819512
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
CCNA1 CDKN1A â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SMARCA4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414052
AR CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10076995
DDB2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678110
PPARG CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15041706
CDKN1B CCND2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TCF3 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19451188 20191379
PAX6 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20053773 17157287
SOX2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22469032 22855803
MAX CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11313917 18393360
PPARG CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11034103 15763423
CCNA1 CDKN1B â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
FLT3 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28522571
MYC CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24704206 26701207
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
DDIT3 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10912181 10510472
FOS DDIT3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
DDIT3 ITGAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19359519
MYC DDX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
DDX5 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18829551
MYC FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20638938 19366810
FOXO1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16670091 19289458
FOXO1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17717603 17922034
FOXO1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20338229 15632117
USP7 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17522590
FOXO1 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18375530
CEBPB GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16418324 11012671
SMARCA4 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414052
FUS MATR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27731383
MEN1 HOXC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14992727
MEN1 HOXC8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14992727
MYC TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CEBPA MYC â—¼   DOWN_REGULATES ✅ - 2.0 0.8 ACSN 11340171 20581311
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
ERG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25277175 20820186
CEBPE MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12947005
EWSR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8164678 11423975
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
MYC CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21925595 23722468
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
TP53 NCOA6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
NCOA6 KDM6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810100105 19047629
NCOA6 DPY30 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810100105 19047629
NCOA6 KMT2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17021013 0607313103
TP53 PAGR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19039327 7013322
TP53 PAXIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
SMARCA4 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7914327 20224553
MYOD1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17194702 17043109
SMARCA4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11950834 33476981
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
TP53 KMT2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
TP53 CDKN2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ETS2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8649821 10510472
PAX8 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8521821
MAX TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7969121 10348347
ZBTB16 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24821728 24821727
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
TP53 NR4A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30455429
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
MYCN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20145147
HOXA5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19918835
TP53 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16917513
TP53 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10749849 16713569
TP53 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 ID2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16557594
ARNT2 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
EWSR1 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HOXA1 TBR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
RUNX1 HHEX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28213513
HHEX HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22068426
HHEX TLE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15187083
TLE1 CDKN2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RELA GADD45G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23681230
CEBPB GADD45G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11012671
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
AR HOXC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21047772 20610535
KLF15 FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPARG KLF15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20592862
JUP BIRC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ETV6 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17606295 19829305
TCF3 ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19321746 0900912106
GATA4 ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17559079 21330551
POU5F1 ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17068183
MYCN ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12670915
ZBTB16 ID2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19723763
PPARG MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16838108 11477074
POU5F1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21425413 22153073
NFIA MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32991581
MYOD1 MAFB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10721736 10642889
TGFBR2 ETS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATF1 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10567368 9694866
ETV4 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14976186
ZBTB16 IL6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NFKBIZ IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15241416 26226212
MYCN HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
ZBTB16 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 MYCN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
HDAC1 GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
HDAC1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16431920
BCL11B HDAC1 â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
PPARG HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21151932 16431920
HDAC2 BCL11B â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
MAX CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11511535 10508165
RELA SOX9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23592398 19254740
RELA GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20660789
RELA IRF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17018379
RELA NFKBIZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20220144
FOS RELA â—¼   PROXIMITY 2.0 0.8 intact 18172215 0705181105
RELA FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10488148
PPARG FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12921977 17320065
PPARG CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15741503 17237441
CEBPB IRF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19717648
IRF4 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22446486 16272311
SPI1 CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18227805 12393465
CEBPA CD14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
RUNX1 IL2RB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15084276 18003603
ETS1 IL2RB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8413220
SPI1 GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
SPI1 CEBPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8695841 22474248
FOS SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9988737
GATA3 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22446486 12027437
SPI1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24503536 19423615
SPI1 CSF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
SPI1 ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9689920
SPI1 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8264604
ETS2 CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12646185
CEBPB CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7513199 21455770
GZMB ELANE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6796478 9404514
CEBPA IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10453008
RUNX1 IL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9036972
ATF1 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7499271
ETS2 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7731694
ETS2 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19829305
ETS2 DUSP6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18321244 18848526
ETS2 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9334186 16189514
ETV4 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8247540
ETS1 DUSP6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20097731
ETS1 HPGD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10650939
ETS1 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7731694
FOS ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 8557686
MAF ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9566892
CEBPA IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7708053
EWSR1 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21531709 15282325
AR IGFBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16825320
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
TFE3 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14962802 11818452
PAX6 MAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12128206
CEBPA RUNX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17431401 5219852
GATA1 RUNX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16628190
RUNX1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16995417 12835475
RUNX1 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
RUNX1 CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17431401
RUNX1 ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
SOX9 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21862616 19254573
ZBTB16 CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19723763
CEBPA ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
CEBPA CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
SOX9 RUNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605170103 17142326
KLF5 SOX9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23266329 24440658
SOX9 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19306868 20593410
ATF1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10683356 7843287
ERG AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8388477 22531786
GATA2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24423874
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
RXRA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15650026
AR RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15650026
ZBTB16 DUSP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19723763
GATA3 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21536859
FLI1 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21536859
PAX5 CSF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21549805 16482219
PAX5 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15676205
ATF1 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12044952
ATF1 ARNT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12527906
NFIA ETV5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
NFIB ETV5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
NFIX ETV5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
SRF GATA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11003651 11158291
CEBPE ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10233885 17347301
EWSR1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16206264 10975680
FLI1 EWSR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16206264 10975680
ZBTB16 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16547399 15623533
CEBPE GATA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12202480
PAX6 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19651775
MAFB MAFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24520122 18199433
EWSR1 ATF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9569031 12527906
FOXI1 PAX8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12702667
NFIB NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
PAX2 PAX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704761 17166926
NFIA NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
HOXA10 PHGDH â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19778996
H3-4 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-3B H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20211137 20651253
TCF3 MYOD1 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 1649701
GATA4 NKX2-5 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ASH2L HIST2H3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DPY30 HIST2H3C â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CCNT1 MYC â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
HIST1H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
KMT2C NCOA6 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
FBXW7 KLF5 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 24398687 29074464 33078455 20388706 20484041 33972717
GATA1 SPI1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10364157 12202480
HIST2H3C RBBP5 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
HOXA5 HOXC4 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
PPARG ASH2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19047629 24368734
SOX2 ASH2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30089852 35140242
MYC MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC RUNX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC WDR82 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
PPARG RBBP5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19047629 24368734
RBBP5 SOX2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30089852 35140242
PAX9 TLE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 20211142
KLF4 KDM6A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 22801502
MYCN HDAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18003922 31856871
MYCN HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31856871 20697349
HDAC2 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30737378 26949739
BMI1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
AFF1 CCNT1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
RXRG RXRA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SOX2 TEAD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
HIST2H3C KMT2C â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
CDK9 DDX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17643375 26209609
MATR3 DDX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
DPY30 MEN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23508102 24981860 17500065
MAX WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 27705803 20946988
WDR5 SOX2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30089852 35140242 29383478
KDM6A DPY30 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17178841 24981860 29785026
SOX2 KDM6A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 28794006 22801502
MAFB FOS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
CCNA2 CCNA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SOX2 NFIB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 21532573 28794006
ASH2L MEN1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
ERG RUNX2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
FLI1 RUNX2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
DEFA1 DEFA3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HIST2H3C WDR5 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HIST2H3C SOX2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CDK9 TP53 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
MYCN FBXW7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19111882 27837025
CEBPA HDAC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15713621 22355045 23898169
SMARCA4 TP53 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
FBXW7 KLF5 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
BAK1 TP53 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ETS1 RUNX1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MEN1 WDR5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
DOT1L HIST2H3C â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
MYOD1 TCF3 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CDK9 CCNT2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
HNF4A NCOA6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 35140242 18552123 15604093 21292004
WDR5 KMT2D â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
TLE1 TLX3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 35140242 19250647 20211142
RXRA MYOD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9692544 16713569
ETS2 ETS1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 9334186
TLX1 TLE1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 35140242 19250647
CEBPB RUNX1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HDAC1 RUNX1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
ASH2L PAXIP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
ETS1 PAX5 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
DDB2 HIST1H3A â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
MEN1 RBBP5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23508102 24981860 17050672 14992727 15199122
WDR5 PAXIP1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 24981860
WDR5 HDAC2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 27705803
ID2 MYOD1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21209940 9242638
SPI1 CEBPA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16983342 12091339
MAF FOS â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21163924 8108109 23661758
HIST2H3C HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
IRF8 SPI1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CDKN1A GADD45A â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
WDR82 ASH2L â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31076518 20516061 23870121 23508102 24981860
CEBPE DDIT3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15588942 23661758 20211142
HNF4A FOXO1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12519792 19740748
MYC HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 22286234 30415952
MYC WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 27320920 35140242 29467282 31767764 30415952
KDM6A NCOA6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17178841 17761849 19433796 24981860 19047629 29785026
NCOA6 DPY30 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19047629 24981860 17500065
HDAC1 WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 27705803 33961781 26186194 33022573 22689669
ETV7 ETV6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 35140242 33961781 26186194
RXRA FUS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32814053 9440806 16713569
NFIB NFIA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 35140242 33961781 26871637
NCOA6 WDR5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
IGF1 IGFBP3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AFF1 CDK9 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
DDIT3 FOS â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ETS1 FOXO1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK9 MYC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
NCOA6 RXRA â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
NCOA6 RBBP5 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
NCOA6 ASH2L â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17178841 19433796 17925232 12482968 17500065 23870121 23508102 33961781 24981860 34079125 19047629
IRF4 BCL6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10601358 11342629
MYC CDK9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12944920 19818711 26687678 11673469 17700062 30415952
NCOA6 PPARG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15604093 19596656 24368734 10788465 11877444 19047629
RBBP5 DPY30 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23995757 31076518 17500065 23508102 24981860 20305087 31485071 25456412
GATA3 HDAC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29453984 26028330 31409898
RXRB PPARG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20211142 22205725 15604093 25609649 30699358
FOS RUNX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11641401 11274169
CEBPB CEBPA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20102225 1840554 15751966
GATA4 SRF â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11158291 11003651
PAXIP1 WDR5 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HDAC2 RELA â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CCND2 CDKN1B â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
RNF2 WDR5 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC2 SMARCA4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
KDM6A ASH2L â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17178841 17761849 31076518 23508102 33961781 20305087 24981860 34079125 29785026 17825402
MEN1 ASH2L â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23508102 24981860 17050672 14992727 15199122
HDAC1 BCL6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15454082 9627120 9753732 16147992 10611298
AFF1 CDK9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32707033 32479599 20153263 33961781 21729782 21030982 23602568 26186194 27684187 23455922 24367103
CEBPA DDIT3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 27555288 23661758 20102225
HDAC1 DDX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20663877 20022962 15298701 19995069 17369852
MATR3 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27460707 27731383 29884807 26496610
MEN1 WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15960975 27705803 23508102 24981860 14992727 15199122
NCOA6 WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17021013 19433796 17925232 27705803 23870121 17500065 33961781 24981860 26186194 19047629
KDM6A RBBP5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17178841 17761849 31076518 17500065 23508102 33961781 24981860 29785026 17825402
WDR82 RBBP5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31076518 20516061 23870121 23508102 24981860
KDM6A WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17178841 17761849 27705803 33961781 24981860 26186194 29785026 17825402
WDR5 DPY30 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23995757 25666610 17500065 27705803 24981860 20305087 33022573 31485071
HOXC8 LHX2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
HDAC1 MYOD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11285237 11684023 16713569 20124407
GATA3 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29453984 34026424 26028330 31409898
HDAC1 SPI1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14647463 16331260 11593411
IRF4 SPI1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12372320 10022840
SPI1 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 9478924
RUNX2 FOS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11641401 11274169
MAFB MAF â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23661758 20102225
ELF4 RUNX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10207087 14970218
AFF1 CCNT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20153263 21030982 27684187 19956800 24367103
SRF TEAD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11136726 12061776
HNF1B HNF1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 2044952 35140242 33961781 10484768
KDM6A NCOA6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
SMARCA4 SS18 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
ASH2L NCOA6 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CCNA1 CDKN1B â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
KDM6A KMT2C â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ASH2L DPY30 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 16189514 25416956 23995757 31076518 17500065 19556245 23508102 33961781 20305087 24981860 21516116 23414517 31485071 22231628 34079125 25456412
ASH2L WDR5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31544921 17925232 16253997 20305087 21285357 15960975 21531708 15199122 17178841 25666610 16892064 15960974 18066051 23870121 23508102 21884981 32076268 33022573 22939629 16878130 31076518 27705803 19556245 17500065 19131338 33961781 24981860 16603732 26186194
ASH2L RBBP5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 31544921 17925232 12482968 16253997 21124902 20305087 21516116 21285357 32296183 21220120 15199122 17178841 16892064 15960974 23870121 23508102 26886794 16878130 31076518 17500065 19556245 19131338 33961781 24981860 16603732 23414517 34079125
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
ATM ATF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20730097
TP53 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 15077116
ETS1 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17213822
CEBPB BCL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19489038 18512730 12665576
TLE1 BCL2L1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ETS2 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19411629 19179380 10082528
CEBPB BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19043455
AR BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21310825 20610535 18196538
GATA4 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15100413 12468531 17272823
TP53 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23852341 19427386
BCL6 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21106671 12594267 15507530
CDKN1A ZBTB16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A KMT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A TLE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SOX9 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19273910 20651055 11514554
EWSR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12560328 18757425 20153576
ETS1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18955504 12740370
ZBTB16 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11719366 24821728 24821727
RUNX1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10617663 23487742 23150456
AR CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 17522055 18687691
FOS DDIT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 31467278 23661758 26264872 29997244 32814053 10523647 20102225
CEBPB DDIT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12706815 20562859 33961781 20102225 1547942 8662954
MAX DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15021909
DDX5 FUS â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
FBXW7 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27795300 31569395 35140242 15150404 33494392 15498494 28007894 23750012 31638140 17646408 28209614 16023596 17157259 25716680 20970423 23791182 32021252 30606768 32345600 17873522 33821962 31152129 20848231 32047362 22524983 17314511 25720964 31285543 32350066 33086033 15103331
TP53 FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23518350 19366810 12824889
TP53 FBXW7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31346036 12824889
FOXO1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21471200 21281751 20650891
FOXO1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12391153 15613482
FOXO1 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20088826 17599040 15632117
HOXA10 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12493691 18391971
TLE1 GADD45A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GADD45A TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GADD45A JMJD1C â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAX GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15021909
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
CCNT1 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12944920 19818711 11673469 17700062 29467282 30415952
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
CEBPB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21098707 20581311 16585579
MYC MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC DPY30 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
CEBPA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12873812
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
MYC CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12873812
NCOA6 RXRA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10866662 11158331 10567404 10681503 11773444 14578865
NCOA6 RBBP5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17178841 19433796 17925232 12482968 17500065 23870121 23508102 33961781 24981860 19047629
NCOA6 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14645241
PAX5 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8521821 22105368 21319196
PAX2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8521821 16320598
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
TP53 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17530187 15456866
TP53 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15469934 14586398
TP53 CDKN2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16169070 16713569
HHEX FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20176809 22844093 22874537
WDR5 KMT2B â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
EWSR1 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10749119 14534527 10508522
ETS1 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14976186 10508522
RUNX1 HDAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
AR CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17617741 20610535 22040886
RELA MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19530226 20186924
RELA NR4A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20018891
RELA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16713569 8798655
PPARG RXRA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22363753 16189514 12763030 10944516 31547433 30404011 20211142 35140242 25609649 17312272 23703729 7838715 19047629 12966085 22205725 14587029 10882139 30595551 30699358 9065481 21833030 9568716 34081964 21478865 9121466 23275339 17579352 19147680 26260846 16713569 12591919 10854698 30651555 32929351 23711995 11877444 15888456 18217139 19043829 17980149
PPARG IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18394717 20064783 20685873
PPARG FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10678274 23657115 18059282
SPI1 GATA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18250304 10364157 10411939
CEBPE SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12032776 12202480
PAX5 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10688639 11179673 21549805
CEBPB IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12574125 10453008
ETS1 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16861237 18625704 10554042
ETS2 CSF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8552081 8981363 9506963
ETS1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11991951 19829305
ETS1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11857377 18181172 8934537
IGF1R IGF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26027733 21645859 8452530
IRF8 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19103645
AR IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 23859805
FLI1 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21531709 15282325
FOS MAF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21163924
MYCN HMGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
RUNX1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22451420 11283671 17894555
TLE1 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17145710 9751710
SRF CEBPB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9032301 11500490 10318842
CEBPB RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17579210 21302301 21612856
CEBPB RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15713650 11668178
HNF1A CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19074951
HNF4A CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19074951
CEBPA DEFA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10706719
AR RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19389811 20610535
AR MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20610535 20946682 17283128
RXRA HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10744771 11027556
GATA3 ARNT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19559773
RXRA HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11027556
RXRA PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19538480
SRF ELK4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9271374 11406578 17200232 7854423 11846562
GATA1 FLI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 10364157 12556498 12724402
PAX6 PAX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10804178 11003833 12721955
HNF1B ATF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9671480
NFIC NFIB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 9099724 35140242 33961781 25258084
NFIB NFIX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9099724 35140242 33961781 26871637
NFIB NFIX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9099724
HOXA11 HOXA10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17688409
KDM6A WDR5 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RBBP5 WDR82 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
HDAC1 ZBTB16 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
MAX MYCN â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
WDR5 NCOA6 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
TLE1 HDAC1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 19101520 22439931
CCND2 CDKN1A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
KMT2D RBBP5 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
BAX BCL2L1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
ASH2L KMT2B â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
ASH2L KDM6A â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
KDM6A KMT2D â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
KDM6A PAXIP1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
ASH2L KMT2D â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCNA2 CDKN1A â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
NKX2-5 TBX5 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
CCNA1 CDKN1A â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
FBXW7 MYC â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
BAK1 BCL2A1 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
WDR82 WDR5 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 20516061 27705803 23870121
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
CDKN1A CCND2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 16765349 5218735
WDR5 WDR82 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ELK4 SRF â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
ID2 TCF3 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
DPY30 ASH2L â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 8153045 21516116
CDKN1B CCNA2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 34591612
RNF2 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16710298 5218667
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
KMT2B RBBP5 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CDK9 CCNT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 9499409 11145967 15328539 17643375 20562857 9491887 20305087 15713662 19387490 11713532 27684187 14627702 23455922 16980611 26659056 15107825 12588988 12944466 14580347 20153263 22959624 16109377 12115727 21729782 23602568 11282025 30649429 19914168 18483487 24367103 20535204 12832472 19818711 12894230 9872325 23064645 30652970 15713661 21697490 22483617 22939629 32707033 11713533 15528190 15546612 10958691 10617616 10574912 18566585 10465067 24981860 33961781 11689688 17700062 26186194 26344197
CDK9 CCNT2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32707033 9499409 16331689 18566585 17643375 10465067 33961781 24981860 21729782 26186194 23602568 11282025 27684187 23455922 11713533 26344197
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
ASH2L WDR82 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
IGF1 IGF1R â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HIST3H3 WDR5 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ASH2L KMT2C â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
BCL2L1 TP53 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
KMT2C RBBP5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
HIST1H3A WDR5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
KMT2B WDR5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDK9 CCNT1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 6613869 18483487
DPY30 WDR5 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BAK1 BCL2L1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
KMT2C WDR5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PPARG RXRA â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CCNA2 CDKN1B â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KDM6A RBBP5 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RBBP5 WDR5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 31544921 17925232 16253997 20305087 15960975 30089852 21531708 21220120 15199122 17178841 25666610 31685992 15960974 27320920 23508102 21884981 32076268 33022573 16878130 28813667 17041588 31076518 17500065 19556245 27705803 24981860 33961781 16603732 26186194 31400120
MYCN MAX â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 2006410 23792191 26062444 24859015 10229200 1935896 18003922 18488021 27728805 10597290 29028833 25175806 17289033 20946988
POU5F1 SOX2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCNT2 CDK9 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DPY30 RBBP5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
KMT2D WDR5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RBBP5 WDR5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MAX MYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ASH2L RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ATM H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
ATM PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
PAXIP1 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15456759 19414588 17690115
ATM HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24821553 11980910
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
ATM FBXW7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17525332 26774286
DDIT3 BAK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17166886 23339468 16597647 14612528
TP53 BAK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22983126 18519674 21233848 15033822 15489892 15105295 10741712
BCL2L1 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 22705850 9463381 22516262 31467278 32814053 9020082 23680104 34098062 18178565 15901672 16189514 17446862 20836993 23055042 19060904 17289999 32296183 10085290 14596824 15292519 29997244 31515488 11175750 9027312
BAK1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15901672 11571294 16189514 16439990
TP53 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11278953 12203124 16931621 9582019 17693666 11118038 12433990 11395510 8183578 11429705 10400708 15242522 11423991 19067706 24336083 18381427 22732402 15988033 16341121 10935506 10094833 16215989 17280505 10744634 12851404 20673369 15851483 8845569 10559267 12168779 11850816 19505426 8564971 11756653 19054058 15566940 12173040 17690113 8635454 18034190 10510469 10101800 11335718 23100276 9400998 9445173 9582400 24098340 22532570 9122197 11420692 11104574 15679092 11748232 12560513 11928223 20400479 20546728 17145718 20567883 20840522 18172861 10566557 10777477 7834749 12806965 17521288 19242108 9000137 21859835
RELA BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18034190 18158998 20056115
MYC BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8845569 11103792 12695333
BCL2L1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 59.0 1.0 Omnipath 22705850 18981409 21458670 28202514 11283018 17525735 29749471 21567405 9388232 18547146 19074440 16151013 21199865 18178565 26496610 16189514 15486085 26186194 17289999 9111042 12419244 25241761 14963330 12853473 9742125 9153240 19427863 21852238 14766748 21671007 15131699 9670005 8596636 24814347 9824152 9027312
TP53 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14963330 16151013 7834749
RELA BCL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10049356 19343319 17000776 11880364 15592513 10733571
RELA BCL2L1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15079071 15536066 17550372 19171876 23430059 8383323 9743347
RELA BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10925251 17673602 14978135 20585448 15231833 14739605 10585435 20066113 16904634 9439816 10733571 15756023 15986355 21722408 12226754 15856023 16453001 18223231 19706766
TP53 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22869582 9582400 9989972 11713584 18172861 23519249 12705879 9000137 11713302
GATA1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17420275 10381501
MYC BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14517295 18802399 16316993 17331788
TP53 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 24814347 12667443 16151013 26556313 14963330 16713569 20837658 24474649 21900206
BCL2L1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 24814347 12667443 16151013 26556313 14963330 16713569 20837658 24474649 21900206
SPI1 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19564417 15892171 31000603
BCL6 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19337254 18648506 15509806 22723377 17392284
CCNT1 CDK9 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24173284 9372954 11483158 9315650 19413330 19664995 23603988 24202322 11709713 16083285 1088347 16552184 10884347 24286312 10747897 17942552 16741955 17287340 92065884 12064478 10348343 14702041
CEBPA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15466360 9442037 12502863 8846917
ID2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17639499 16557594 21900881 16428453 11706002
MYOD1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10373569 25211658 18211587 18521215 16351709 17959144 14749395
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
AR CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16281084 10076995 11606392 10606230 20610535 10809237
FOS CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12705898 12087103 14755691 16141357 10891399 11789587 21864583
RELA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18954936 22305266 23037503 18269916
RUNX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21913213 17438369 19179305 15107836 12391164
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
FOXO1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17609436 23574718 23918930 24769335
KLF4 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10749849 23884787 18483411 21652709 23861801 19737957 21132436 21224073 22750490 21763782 18645021
CEBPB CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10982390 15466360 15041706
PPARG CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19551868 19103521 19208833 16985067 18509005 15041706 15345676 16091736
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
FOXO1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15084259 19380174 21708191 15084260 21613825 17940099 11154281
CDKN1A CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23443559 26186194 25241761 27107012 8756624 15169570 25416956 16765349 31515488 16189514 32296183
CDKN1A CCNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12383116 25241761 8756624 29997244 16982699 7478582 10022926 32814053 15232106 16009130 16189514
CDKN1A CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 23443559 26186194 21308745 9660939 8756624 15890360 9380407 8242751 8662825 12947099 9632134 17679094 26496610
FLT3 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10323868 17254966 28522571 19075005
TP53 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15145945 15988033 19235838 10516009 21478095 14984207 19427386
FOXO1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21418583 17015685 12359217 12391153 11094066 18593906 19281796 18787071 23160481
FOXO1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11073996 19380174 10783894 20673124 11094066 15668399 17646672 21708191 15084260 21613825 17940099 11994454 11154281
TP53 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21340684 20066118 20457558 20182602 6396087
CDKN1B CCNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15583032 29997244 7478582 10022926 18692475 32814053 16189514
CDKN1B CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25910212 16189514
CDKN1B CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17145710 8684460 26186194 9660939 17254966 15890360 16209941 12947099 12501191 26496610 9724724 9311993 9716181
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
MYC DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15021909 18483244
CEBPB DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8051100 16757577 10085237 8662954
DDIT3 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 7588595 21983012 11050169
DDIT3 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18772138 22031759 17709599 15688424 21471847 18850010 17197543 15659384
DDX5 GATA3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17495528 15343269 19718048 11682626 28539435 14675539
DDX5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24219989 15660129 20876186 19626115
DDX5 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15298701 17369852 20022962
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
FBXW7 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15498494 17145710 32047362 28007894 31569395 33821962 20399964 20970423 17157259 16023596 20852628 15103331 15150404
CEBPB FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18391971 11893744
AR FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18391971 17202144 16713569 12482965
HNF4A FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12519792 19740748
FOXO1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16670091 12966085 17317207
TP53 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10749144 22801474 11221850 15031557 22262183 10321740 17700520 11420680 10094833 23114628 8892753 23948959 9405685 21394211 9931282 10435630 12007564 15721278 17440969 23576563 9566896 9233781 21836608 21245169 15186775 17063488 9154806 10327059 9191059 17344317 9519881 20797428 18350249 7624148 10566557 17084916 16714289 20840860 15735726 12806965 18225552 16581545
MYC GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15721278 9190899 10913183 15021909 14519204 9811446 21835778
TP53 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16990795 15603758 14627995
MEN1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11526476 14508515 16713569
MYC MAX â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MAX â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16596619 21988832 10229200 17471507 26267534 15572685 18003922 20382893 35140242 17418410 25609649 16352593 31767764 17072308 17289033 10918583 9528857 14749374 21807113 19623651 18620061 25522242 32296183 16140957 16705173 19578763 26496610 12584560 17157259 17643117 24951594 20946988 10465786 12706874 12821782 9184233 17353931 10611234 32140074 8266081 20691906 16410719 21150319 10593926 12660246 27859590 12553908 8224841 10319872 2006410 16287840 16606833 23816886 9708738 17314511 9886493 27705803 33298911 33961781 20936779 12824180 9680483 17700062 29467282 30415952 12391307
IRF8 MYC â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10734131 11672593 11875494 11964313 12032143 12417340 12811837 16243976 16413922 16597464 17404308 17485448 22461508 23390297 24091328
MYC MAX â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
GATA1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24336126 19522008 12832487
GATA2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19522008 22951020
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513
MYC CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8386381 10713672 12835716 7608142 12937171 14519204 14729654
MYC CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15681429 17082780 7556187 8076602 20097210 12695333 15867211 19259613
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
MYC ETS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18586674 12695333
MYC CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7526316 11511535 10508165 9339900 15988028 20857481 11060032 14519204 14660677 10956386 21790895 11264343
MYC ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12447693 12695333 12824180 18437010 18483244 12545167
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
MYC MAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508165 15665468 8385351 8649388 8521822 22384171 1406956 17341548
TCF3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
MAX MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 17145710 16287840 25609649 12821782 16606833 16596619 21807113 25522242 20691906 19578763 24951594 8224841 17643117 9528857 12391307 16705173 21150319 10229200 21988832 15572685 9680483 2006410 17314511 14749374 12553908 17289033 17418410 19623651 12824180 17157259 12584560 26496610 20946988 20936779 8425218 23816886 17353931 10319872 17471507 18003922 16140957 20382893 12660246 8266081 7565735 32296183 10465786 26267534 17072308 27705803 9184233 18620061 10918583 17700062 10593926 10611234 16352593 9708738
HNF1A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
ZBTB16 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14645547 19723763 19444914 18246121
MYC CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8425218 15121849 11602341 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
H3-4 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
PAXIP1 PAX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10908331 17925232
WDR5 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
RBBP5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
RBBP5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
SMARCA4 SOX10 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10757804 16373334 17325040 23874858
MYCN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20811720 11107122 10050884 21862876 20145147 19885598
KLF4 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18511453 16244670 17308127 21132436 17659301
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
ETS1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12145208 19022222 8649821 10510472
NFIA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12145335 10505791 10634504 8816507
CEBPB TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19135161 23564453 19075931 24333671
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
TP53 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11818510 16895524
TP53 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15131018 11001824 12089352 20633551 24205274 17097318 10023442 17600529 17014845 8710868 12444079 16181796 22033326
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
TP53 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16931621 8270002 9275177 19671680 16571800 8641461 9360984 21952947
TP53 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12631625 18281476 18174288 21460853
TP53 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10101800 23810988 15661074 7566179 15713654 18084616 9525742 20003326
TP53 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16432214 20080630 17242190 20422012
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
CCNA2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14640983 10884347 16713569
TP53 IGFBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7566179 17409411 18431400
WDR5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ELK3 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 7958835 15548518 23063436 15684718
ID2 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9242638 8380166 21209940 1922066
PAX7 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18854138 15501225 17548510 18508329
SRF MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17377068 8744946 9658178 23406902
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
TCF3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9242638 1649701 10915743 9001211 9184158 9050988
KDM6A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24561908 17713478 20123895
IL6 TGFBR2 â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 11306493 15099563 15356132 15573129 18209571 18555777 18555778 19581928 20138012 23034983 23567181 24011634 24346288 25002027 25582338 26201938 26268945 27557510 7590867 8837607 9845545
FLI1 TGFBR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10749119 14534527 10508522
CD14 IL6 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRF4 IL6 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 10754326 10952726 11438547 11875494 12907458 14660645 15218058 15465827 15644117 15749903 16243976 16413922 16713974 16878026 17404308 17485448 20580461 22003200 23390297 24378531 7594497 9743347
IL6 CEBPB â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 11306493 15099563 15356132 15573129 18209571 18555777 18555778 19581928 20138012 23034983 23567181 24011634 24346288 25002027 25582338 26201938 26268945 27557510 7590867 8837607 9845545
SPI1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15013752 23509362 18680724 19502584 25567680
FOS IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10037779 10542237 9671466 2511437 25567680 20351184 24994901 11356008 11028561 12667961 18502099
RELA IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 114.0 1.0 Omnipath 26596471 19124729 10373597 9523851 23595969 28270510 21537341 17982049 15226358 18243142 12200447 20371366 24664372 23874122 14532843 18942706 10975857 21278793 10469356 22547075 17490702 11459775 23335080 10569191 19707556 19687301 7499267 8290595 23857586 24676671 18061164 11058167 12887736 15013753 15158360 22661093 20935672 20511231 17350185 10903137 16112536 27413250 21810609 16984731 16166627 18469854 12881425 24012417 23386688 22105366 8752656 12176740 27371733 22578249 18057724 20351184 10329846 19164127 10542237 11564778 20221401 15517885 19122653 20534538 7876168 27211851 9516466 18996370 8824277 18310089 21104991 25888873 12359431 11327783 20066113 20100571 19703987 19469019 21106671 16960103 18502099 16043358 21996739 20650996 22021035 11120852 12672795 12058956 18483242 22189669 14976218 17495236 11007957 21131967 11975924 27337441 9182853 10963848 17040605 11504280 15756023 10823821 17932106 19966855 20696864 12177065 8679226 9199307 17196927 20457835 21098092 17532054
CEBPA IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15158360 10748205 11975924
AR IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12237244 8824277 19074897 11049111 17374439 11410519 20610535 19363165
CEBPB IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 8441418 10748205 21069809 1327803 7543095 11004486 9312180 23595969 15389813 12853840 7651415 7744000 9523851 19026986 17332680 8786324 8910763 11250916 23361365 11114305 7821611 21127061 9516466 10816606 1730090 8234276 15044620 9282937 16784777 20511231 1427600 24472318 7818522 10903137 23874122 8336793 22558159 14600152 19632992 9661072 14530280 1421375 11160296 9182853 22895549 25382637 9378980 9648065 24012417 11866474 8725624 12177065 8752656 11035101 18955501 2112087 15613028 9442386 9199508 7744784 15688424 8346247 22074460 17955490 12706815 11594800 11120852 10435001 8325885 19782405
MAF ITGB7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14998494 17490615
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
SOX10 HDAC2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 26423937 12198163 10856243 21423190 21653862 17699610 22814607 18803322
RELA CXCL8 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15079071 15536066 17550372 19171876 23430059 8383323 9743347
CEBPA CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22685373 25119735 8999951 18199703
PPARG CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19395102 18485432 20107546 20554962 16303327 20889551 15331599 12695526 15720834
RELA CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 129.0 1.0 Omnipath 12820969 24337575 15289496 9405619 9698090 20038977 15057743 21665565 24260304 10817569 14631383 10969814 15005855 19668231 16325549 19732956 8207232 18281166 27856305 23894194 9388261 26340924 10975857 10745031 20194077 10928981 16553947 17565687 16764699 22848596 15531761 16105834 16803583 9510190 15355994 18221537 12643600 20053934 11716760 8617886 12218154 12707271 23637609 27076634 8878392 17917246 12163591 16829531 16818736 14670967 12038622 15958549 18362169 8413215 19734226 23386688 11297551 15950427 17362989 16455661 27371733 11953364 8413306 18074095 11973337 18786178 19376732 19837667 17276517 15517885 11342414 18669446 7876168 15350531 14645117 22891766 18034886 11564889 12748173 17586662 18996370 15223809 17041011 12485925 16004996 15079071 21343296 26618242 18435575 17636245 22340043 19173296 24634218 11120852 10477716 21343177 12058956 17045242 19786024 24048734 24770886 10202011 18309103 11864912 21131967 19064995 10530453 12716652 16418726 28283022 18723827 17040605 21255844 15615716 17932106 19966855 20696864 15387324 21451502 15722553 15879558 12855659 12883201 15688424 18045535 10506755
FOS CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11973337 18317936 12218154 22095787 12748173 10969814 15005855 17586662 16818736 24048734 14686613 16846747 15057743 15615716 8999951 25567680 19173296
CEBPB CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 23051921 10775602 17135982 8969274 17997161 18512730 21471847 24554449 14645117 15085176 17845418 12707271 12748173 19489038 22031759 8234276 19064995 8207232 16989899 27856305 11991987 19109189 17471497 19786303 16809637 16818736 21255844 19734226 24038085 18772138 19805069 20861254 18487355 11390611 15688424 10462040 16803583 8999951 11120852
MAX CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
RELA AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24466341 16619263 14576180 15517885 14715080
RELA CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9414129 7636192 9190901 11418664 18230685 9596659 8135780 21071440 14741709 11395507 8934574 18285351 10608823 18056447
RELA BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 15231833 15050749 19343319 17673602 18226221 23250755 17000776 11880364 21279667 21765477 10733571 18566231 12010810 15723831 10823821 11297551 16291753
RELA BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15050749 17673602 12687011 12714587 15756023 12010810 18566231 16453001 20103608
RELA CD86 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10586028 12574356 15949284 19164127 15895390 18929846
RELA CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11313274 17031478 19164127 9733827 10075983
KLF4 PPARG â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10432118 10925299 12193690 21093321 21670502 23390297 6357187
CEBPB PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22473998 23934183 7557387 12524424 16431920 22610404 15110775 18694725 17242167 16054042 15158467 9950217 10862621 20829347
GATA3 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18522800 15632071 15896659
GATA2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18522800 19772889 15896659
CEBPA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22553076 20725087 15664998 15110775 18619497 19059241 9367890 15158467 23071089 10862621 15632071 16580992
PPARG RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12878983 18715135 20589837 12704187
RXRA PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 12763030 25609649 20211142 11877444 16504037 17579352 16713569 9065481 22205725 23331499 22363753 10854698 19147680 19043829 12591919 9568716 10882139 10935544 17980149 26260846 21478865 14587029 23711995 9121466 18217139 31547433 7838715 19047629 23275339 21833030 12966085 17312272 11237216 15888456
RXRB PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22205725 25609649 23331499 20211142 15604093 11237216 18988627 10882139
PPARG RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 12615696 16189514 18988627 15130092
CD14 ITGAM â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10201950 16751103 3537192 2462607
CD14 FLT3 â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
ETS1 IL2RB â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 15001984 15111329 15181457 16391805 17615296 21041997 21081489 22608498 9157999
SPI1 GATA1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 10734131 10753833 12803886 16283355 16418395 20510871
SPI1 GATA1 â—¼   PROTEIN_INTERACTION 6.0 1.0 ACSN 10734131 10753833 12803886 16283355 16418395 20510871
SPI1 FLT3 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10734131 11672593 11964313 12032143 12803886 12811837 16283355 16418395 20510871
GATA2 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19620289 16254139 19491391 24583263
RUNX1 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23817177 19339695 20972335 24037986 18316480 19208846 17994017 12576332
CEBPA SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17671233 24429361 14636649 20972335 12949251 14592841 12032776
SPI1 FCGR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12393465 7869026 8035786 12130529 15304324 14734612 10820245
SPI1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10823830 11481336 14962802 19801646
SPI1 GATA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14559995 10411939 11023493 11001896 20304827
SPI1 CSF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17116688 8264604 9506963 8302571
SPI1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10523830 9858537 23056458
SPI1 ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9689920 8756629 16247445 9192779 14732495
SPI1 ITGAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8955212 19747912 12393465 19502584 9295016 15163413 8095266 25005557
GATA2 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10411939 10364157 18250304
GATA1 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10411939 10753833 15676205 10364157 12202480
CEBPA SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10397723 12091339
SPI1 ITGAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8095266 15676205
SPI1 IRF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10570299 9593745 10734131 17386941 11483597 17200120
ETS1 CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9190901 7478534 8611694 15907486 12475968 15123671
FOS CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9190901 1900839 8135780 11509589 9028942 12432566 7579683 8631792 9862439
IL3 CD86 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15034038 15549123 17200410 23026134 23125331 23762788 24778133
IL3 CD40 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15034038 15549123 17200410 23026134 23125331 23762788 24778133
RUNX1 IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11997340 9036972 20506188 15735013 10023677 8180380
ETS1 IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8704203 12387738 25861992
CD40 CD86 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
ETS1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9349499 8262053 1722028
IGF1 IGF1R â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11237532 12181198 17145802 19631971
AR IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19318566 15033751 17202144 19250214 20610535
IGF1 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21798082 23331499 8452530 21071413 12067807 1852007 21645859 8408032 14604834 19258508 11287679 23675206 19029956 2877871
HNF1A IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7836361 10050749 15933209 12031966 17210751 8943227 8584026 11544200
AR IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24914937 8580999 17363459 22739988
IGFBP3 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10823924 11600567 22578544 1383255
ELK4 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23063436 9734357 8764983 9111305 9130707 8986626 11846562 20637912
SRF FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9315625 10742173 8864058 8986626 19581295 9690619 10777594 11846562 12242287 2104799 17938209 9111305 8007980 12760745 11862715 1902475 8423791 10642500 10330504 10961986 9032300 2511007 8164681 7854423 17182846 2200737 9271374 10369679 8413226 19173292 9349499 1630900 8262053 10319327 7910456 9545312 9571041 9734357 8764983 12231642 2493627 14693367 18557893 7588632
CEBPB FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15860545 18180320 21292824 12773552 10531366
HMGA2 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17324944 21566082 17005673 14645522
BMI1 RNF2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
BMI1 RNF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16710298 22493164 22902369 20068231 22325352 25355358 17157253 16751658 26496610 16714294 26468281 26151332 12183370 12589020 21772249 25843776 20601937 32296183 21676867 27647897 15563468 27705803 16359901 24457600 19636380
TCF3 PTCRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11490000 17050604 11870636 12566462
CD40 BIRC2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19426221 12374738 24298274 9718306
CD40 BIRC3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19426221 12374738 24298274 9718306
PAX6 MAF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11222774 21998302 14521912 19223471
RUNX1 CSF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16007221 17589498 9209363 8577711 8585955
CEBPB CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9990015 19581927 10603305 15509789 16431920 19663997 15110775 7862113 10854425 17301242 24216764 20179325 15158467 17646392 18622014
CEBPA ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17360796 19620402 8756629 16247445 12949251
ZBTB16 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11920165 20731660 18504436 10023668 14527952
ZBTB16 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10023668 18246121
AR ETV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17634427 19789348 20610535 17505060
AR ZBTB16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15334066 20610535 16637071
AR KLF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19460858 20610535
HNF1B HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10518495 8290348 11585914 16479257
HNF4A HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8367288 9111350 9792724 8674436 11717395 9313764 9837989 9204893 9232592 1734282 20850486 8735941 11145965 11085951 10331424 8808405 12601360 16670373
POU5F1 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20505756 12136102 17324942 15988017 17068183
NKX2-5 GATA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19479054 15653675 16137232
TEAD1 SOX10 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
FLI1 GATA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8510925 20110178 21205096 12724402
FLI1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12556498 12724402 16189514 10364157
HNF1B HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15486044 1363228 16793932 15001636
KMT2D H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19219072 18022353
KMT2B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19219072 18022353
GATA1 GATA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19114560 12432220 20670937 14695898 21853041
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
NFIB NFIC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9099724 25258084 16189514
FOXI1 PAX8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15459102 15188428 12538519 15604103
GATA3 H3C2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
GATA3 H3-3B â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
GATA3 H3C14 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763