Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GSK3B CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
FOXI1 PAX8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12702667
NOTCH1 PAX8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18495817
TLE5 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20676368
ERG AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8388477 22531786
GATA2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24423874
AR NOTCH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22347519 23145211
TBR1 AUTS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20615956
DDB1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
CTNNB1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18948405 15031118
NLK CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12556497
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
GATA3 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21536859
ERG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25277175 20820186
ESR1 HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 19039095
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
GATA3 FOXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25303530 22120723
GATA1 RUNX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16628190
HDAC1 GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
NOTCH1 GATA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15689374 11719365
RUNX1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16995417 12835475
NOTCH1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15356142 17658279
GATA3 TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951069
XIAP GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GOLGA2 XIAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
MYC HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20388374 19021144
HES1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19129776
HES1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10066785
HES1 TLE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19250647 16608701
HES1 TLE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24270405 8687460
NR3C1 KLF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27777311
KLF5 NOTCH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21868761
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
NOTCH1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10644343 16847353
MYOD1 MYH7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1939278 17111365
NKX2-5 MYH7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20559569 11555635
TEAD1 MYH7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8253797 10998641
NFIA MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32991581
NOTCH1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12050162 10066785
NFIA NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
NFIB NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
NOTCH1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17537801
TCF7L2 TLE3 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
DDB1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24249678 26679995 25189618 34026424
PAX8 AES â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 32296183
TLE3 TITIN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 TITIN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 25604459
TLE3 ACTS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TLE3 EF1A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TLE3 CO1A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HME1 AES â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 35140242
HME1 TLE3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 35140242
STAR7 AES â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STAR7 TLE3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
RIPP1 TLE3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RIPP1 TLE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RIPP2 TLE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RIPP2 AES â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RIPP2 TLE3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HLX AES â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AES PROP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23732115 32296183
AES PAX9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 32296183
VENTX AES â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 BCOR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 26487511
FOXC1 NFIX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 35140242
HDAC1 PRDM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19124609 22733990
TLE3 LDHC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC RUNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
TLE3 MYH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TLE3 MYH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TLE3 MYH3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TLE3 MYH4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TLE3 MYH7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TLE3 MYH8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PAX9 TLE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 20211142
TLE3 PYGM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOX2 UBR5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30894683 23667531
SOX2 TEAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
TLX2 TLE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 20211142
VENTX TLE3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DDB1 HIST1H4A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HIST1H4A SOX2 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
ANDR TLE3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33640491 28611094 34585037
ANDR BCOR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31925334 33640491 28611094
SOX2 NFIB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 28794006 21532573
TLE1 VENTX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 20211142
TLE3 TLE2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
DDB1 HIST1H3A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
NLK TCF7L2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ANDR ERG â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20478527 22722839
BCOR HDAC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23658227 16713569 10898795
HES1 TLE2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9874198
HIST1H2AA HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
GSK3B CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 16293724
HES1 TLE1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
HIST1H2AA HIST1H3A â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
HME1 TLE1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 16571670 35140242 18611861 19956621
CUL4B HDAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25189618 34026424
PRDM1 TLE2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9887105 16713569
TLX1 TLE1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 35140242 19250647
TLE1 TLX3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 35140242 20211142 19250647
TLE1 TLE4 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
HDAC1 RUNX1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
HIST1H3A HIST1H4A â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
FOXC1 NFIC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 35140242
TLE1 FOXG1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18611861 22354967 16314515 11238932 24356439
FOXL1 TLE3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 35140242
FOXQ1 TLE3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 35140242
HDAC1 NR3C1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
RNF6 ANDR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28324045 19345326
PAX6 ANDR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19790232 21935435
RIPP1 AES â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32296183
AES TLE1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 22354967 17353931
AES TLE3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 17353931
SOX2 FOXC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
NFIB NFIA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26871637 35140242
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ANDR GSK3B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15178691 15361837
SIX2 TLE1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28514442 12441302
ESR1 GATA3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26153859 23403292 25303530
PHF12 HDAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26496610 26841866 23752268 28514442 11390640
HLX TLE3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
HLX TLE2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
PRDM1 TLE1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9887105 35140242 16713569
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MYC GSK3B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16247449 20713710 19131971 21150319 31638140 29467282 11877389 33541412 14563837 8247524
HDAC1 ANDR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 34585037 11994312 26468294 15835920 16713569 15640443
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
GATA3 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 34026424 29453984 26028330 31409898
NLK LEF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12556497 24394665 20194509 12901858
TLE2 TLE1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9874198 16189514 33961781 24981860
FOXG1 TLE1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
GSK3B TLE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
AR GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20127713 20610535 18687691
GSK3B AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15361837 15178691 14985354
AES ANDR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11416139 33640491 16713569
LEF1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16741972 16474850 19351848
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
AR TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12799378 20610535
TCF4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12799378 16713569
BCOR HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 10898795
ESR1 NFIB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26153859 18414489
ESR1 FOXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25303530 18414489
GATA3 MYH3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19559773
RUNX1 HDAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
TLE2 HES1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8649374 8001118 8687460
TLE3 HES1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8649374 8001118 8687460
TLE4 HES1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8649374 8001118 8687460
NOTCH1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
NFIC NFIB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 35140242 9099724 25258084 28514442 16189514
NFIB NFIX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 35140242 9099724 26871637 28514442
NFIB NFIX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9099724
PIN1 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19151708
PAX6 PAX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10804178 11003833 12721955
TLE1 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17145710 9751710
XIAP TLE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14685266 19590513 22304967
XIAP TLE2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14685266 19590513 22304967
XIAP TLE3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14685266 19590513 22304967
XIAP TLE4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14685266 19590513 22304967
LEF1 NLK â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
TLE1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 22439931 19101520
CTNNB1 TCF4 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
TLE1 HES1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 33961781 19321451 18611861 19956621 8687460 24270405
HDAC1 PHF12 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
SIX2 TLE3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 28514442 32296183
TCF4 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219694 17318191
TLE1 LEF1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 15768032 9751710
CTNNB1 GSK3B â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
TCF7L2 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 11713475 5214798
CTNNB1 LEF1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CTNNB1 TCF7L2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
GSK3B NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16944320 15465828 12123574 11967263 14663202 8524413 21828089 16713569 9832503 15020233
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
GSK3B MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 73.0 1.0 Omnipath 17081983 18463697 21646472 30037819 26751215 25647305 2663470 20080742 19797085 30003124 16855632 12040186 18679417 11018017 23331499 29229669 16611981 21071413 24265759 20068231 10671551 16039586 17570479 16023596 29258530 12615961 18669648 21113395 22461507 19131971 8247524 16247449 20604938 19575820 15150404 22481935 23668310 19651622 17444818 23964270 20537194 22893788 27684546 24662831 25333250 20399964 11877389 14563837 18408012 17052453 18455992 15212693 16371461 11274345
GSK3B KLF5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24398687 20484041 28480051
GSK3B NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 30250038 18838540
GSK3B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 183.0 1.0 Omnipath 22415718 11967263 27158593 29455668 19303846 19797085 8638126 19293931 23056571 22662165 25352148 16611981 27068260 28337019 10671551 21743491 20688898 16293724 23721711 23552738 18687691 28977889 19622173 12051714 25241761 27683053 28549350 22699938 19565571 23076981 21562161 19575820 20219694 20537194 10330181 21986938 29183346 27773936 11251183 19711366 21035499 19675674 7542250 23151663 24451375 14663202 23804296 8524413 25639486 23770025 18070361 26892600 30143633 9233789 19667122 27507058 19061640 19223551 29387014 23331499 16199882 11533658 18644116 24501426 24913829 11835406 17318191 26014148 25366337 28183999 22640743 26910375 12000790 12114015 18387957 19107203 9832503 16371461 29805709 27462866 20137080 27902311 12040186 19576224 25644994 12615961 19060929 25897075 12851486 15465828 17053159 18952601 10228155 15020233 17444818 20140245 26453498 17052453 16944320 24015932 23602568 24975844 24931005 28948000 20080742 23209942 30271168 28220106 16520547 28430641 11818547 25546293 27672271 11955436 11154277 26373837 16039586 23778311 28697793 20302655 25136145 26905812 22216350 8666229 12957350 23109003 10074433 28529629 20215423 21329734 11254732 9501208 27098453 27281614 30279527 19631635 25482131 18455992 24403311 11274345
FOXI1 PAX8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15459102 15188428 12538519 15604103
TLE4 TLE5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 11290324 15187083 9783587 11266540 8365415 9887105
TLE3 TLE5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 11290324 15187083 9783587 11266540 8365415 9887105
LEF1 TBXT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10704849 12032083 12234972 11447280 14575694 18948405 15292219 15579438 16139800 14557550 10953028
CTNNB1 TBXT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10704849 12032083 12234972 14575694 18948405 15292219 15579438 16139800 14557550 10953028
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
AR KLF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19460858 20610535
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
CTNNB1 TLE2 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 10485845 11934263 9819412 8955148 19460168 15768032 15121853 9118222 10080941 10831834 11713476 8756721 9751710 11136974 8757136 9488439
CTNNB1 TLE4 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 10485845 11934263 9819412 8955148 19460168 15768032 15121853 9118222 10080941 10831834 11713476 8756721 9751710 11136974 8757136 9488439
TCF7L2 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24214913 14706452 19347947 24317174
CTNNB1 TCF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12086873 11943708 13679048 15806138
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
CTNNB1 LEF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17785445 15473860 11326276 17335794 15728254
PIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16713569 11533658
CTNNB1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17145710 9488439 11713475 12446687 17143293 27902311 16569639 22014570 16724116 11955446 16442529 26350900 19202075 17050667 20126258 22056988 16306047 17914096 19443654 18391971 21670201 22155184 10080941 17283121 16230076 22304967 16630820 15684397 11713476 12861022 19304756 20492721 19816403 18772112
CTNNB1 TCF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 24532795 11713475 18281465 25402006 16724116 12799378 12944908 12727872 23331499 15060161 17412698 22080605 21743491 17875931 12657632 17983804 20126258 17318191 24798214 24876153 29361949 17909039 23449499 22699938 18595660 9308964 16007074 15331612 11713476 15665104 17072306 15525529 17962194
CTNNB1 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 16510874 23151663 11751639 15735151 17143293 16204248 23331499 12556497 21071413 14638683 15768032 18296023 12748295 21743491 11835406 16510875 18077326 8757136 9065403 20123964 15728254 17517646 21078818 15684397 8892228 10890911 15525529 12077367 9419974
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
GATA3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17616709 20130088 20068169
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26153859 25303530 10096242
GATA1 GATA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19114560 12432220 20670937 14695898 21853041
GATA1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24336126 19522008 12832487
GATA2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19522008 22951020
TLE4 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
TLE2 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
TLE3 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
HDAC1 TCF7L2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
NR3C1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15826950 16762839 18762022 18028994
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
NOTCH1 HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10520600 11120788 10066785 16869730 12814948 7566092 21956839 9819428 10933396 11866432 20007915 10205173 11741889 19165418 15546612
NOTCH1 HES1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23343194 19000719 18495817 16039586 19619488 17143292
TLE2 LEF1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10485845 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
TLE3 LEF1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10485845 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
TLE4 LEF1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10485845 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
TCF7L2 LEF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15473860 20802155 17335794 11326276
LEF1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19620402 18202148 17132729 19653274
NLK LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 28.0 1.0 Omnipath 16714285 14960582 23331499 22373574 12482967 12556497 24816797 12901858 11274345 20194509 19623618 18855897
NOTCH1 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11604490 16713569 18988627
LEF1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
LEF1 TLE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 23331499 15768032 9751710
MYC PIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC PIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
TCF4 MYC â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10391247 11955436 11967263 12051714 15001769 15082531 15576399 16039586 17143292 17936032 19619488 20705860 22290435 22761862 23343194 24023259 25730849 7542250 8666229
TCF7L2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 12095419 19561604 19895682 15579438 26947016 16204248 12799378 12907606 17360646 9727977 21533051 20133699 15576399 19784072 24447505 12591729 20818421 18852287 11973610
TCF4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21533051 19778454 15928669 20133699 18852287 19561604 19662654
PRDM1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12626569 11279146 10713181 12032779
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
TCF7L2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
TCF4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
PIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26655473 15048125 30723410 23716601
PAX7 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18854138 15501225 17548510 18508329
NFIB NFIC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9099724 25258084 16189514
NLK TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 16714285 14960582 12556497 12901858 11274345 20194509 18855897
NLK TCF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14960582 2861485 12556497 11274345 20194509 18855897
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
TLE2 TCF7L2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10485845 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
TLE1 TCF7L2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10485845 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
TLE4 TCF7L2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10485845 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
TLE3 TCF7L2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10485845 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
TLE1 TLE3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10485845 11934263 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
TLE3 TLE4 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10485845 11934263 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710