Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PAX8 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9413150 11453662
NFKB1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704864 11313951
BCL2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15210690
TRIM27 BCL6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GOLGA2 BCL6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
BCL6 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
BCL6 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14654791 11914273
BCL6 IRF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10601358
HDAC3 CCND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16461912 0506281103
CCND1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16461912 0506281103
KLF8 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21518760 12820964
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
SOX17 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21957254 19479035
RFX6 CCNK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RBPMS CCNK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RHOXF2 CCNK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CCNK STX11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GORASP2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GORASP2 GOLGA2 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 21900206 2001699 8089645
GRB2 HNRNPF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DDX6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAPK14 SP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20682789
MAPK14 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18253836
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
GFAP SMARCB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18691180 9650586
CRX PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19850845 18172122
CRX PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19850845 18172122
MAGOHB IKZF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
LDOC1 IKZF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
LDOC1 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HHEX HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22068426
HHEX TLE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15187083
C1orf216 MTUS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
C1orf216 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
PRKAA2 KIFC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CFAP206 C1orf94 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CFAP206 UBXN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GFAP PPP1R16A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RHOXF2 RBPMS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NFIA MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32991581
SMAD3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11711431
CALCOCO2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UBXN11 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
BAHD1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRAF2 IRF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
AR SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20739403 20610535
SMAD3 PAX8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14623893
SMAD3 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11790301
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
HDAC3 GATA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0607926103 17075044
L3MBTL2 HDAC3 â—¼   COLOCALIZATION 2.0 0.8 intact 7719892 20385135
KLF3 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18687676
NFE2L2 OSGIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18535259
IRF4 PRDM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16919487 20064451
FOS NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20188076
NFKB1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20660789
TRAF1 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
IKZF3 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GOLGA2 IKZF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GOLGA2 KANK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
GOLGA2 ARHGAP32 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GATA2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24423874
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
ABI2 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CSNK1A1 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15747065
U2AF2 CPSF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219196 17024186
U2AF2 SRPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SOX17 LEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17218525 17875931
FOXP2 TBR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
C1orf109 TRIM27 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
GFAP BAHD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOXI1 SIX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17035528
SIX1 PAX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17035528
SIX1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12874121
FOXI1 PAX8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12702667
NFIB NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
KIFC3 ZGPAT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
C1orf94 RBPMS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FAM124A RBM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NFIA NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
HNRNPF VPS37C â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
OLIG3 PROP1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
GOLGA2 GORASP2 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
PAX9 VPS37C â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
KRTAP10-8 VENTX â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
MYC U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC MFAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
LMO4 LHX4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 24981860
PAX9 TLE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 20211142
VENTX TLE3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HDAC1 PRDM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22733990 19124609
SIX1 TLE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16189514 12441302
TLX2 TLE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 20211142
FRS3 STK16 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
LHX4 ABI2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TLE1 VENTX â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 20211142
BAHD1 HDAC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 21252314
SOX2 NFIB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 21532573 28794006
FOXP2 TBR1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25232744 21653829
AR CCND1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
LSM2 MFAP1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MYC HDAC3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23079660 31155734 22002311 18483244
TLE1 TLX3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 35140242 19250647 20211142
KLF5 NFKB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16102021 16713569 14573617
TLX1 TLE1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 35140242 19250647
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
HDAC9 BCL6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16147992 12590135
MLH1 PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15225546 32814904 28439008
FRS3 RFX6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
C1orf216 PPP1R16A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
HDAC9 HDAC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12590135 16611996 10487760 10655483
HDAC1 PPARD â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18037904 11867749 16189514
FOXL1 TLE3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 25609649
FOXQ1 TLE3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 25609649
PPP1R16A TSSK3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
ZGPAT HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24116224 19644445
GATA3 HDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29453984 17075044
SOX2 HDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 21532573 23667531
HDAC3 GATA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 11567998
NFIB NFIA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 35140242 33961781 26871637
MFAP1 OLIG3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
IRF4 BCL6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10601358 11342629
FOS SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21829441 9732876
SMAD3 LEF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10890911 15750622
PHF12 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 23752268 11390640 26496610 26841866 33961781
HDAC3 PPARD â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12943985 11867749
PRDM1 TLE1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 35140242 16713569 9887105
HLX TLE3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
PRKAA2 VPS37B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
BYSL KRT40 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CFAP206 KRT40 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CFAP206 CRX â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CRX RHOXF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
HDAC1 BCL6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15454082 9627120 9753732 16147992 10611298
HDAC3 CCND1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15713663 12048199 16461912 20484017 15558026
MYC MLH1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12584560 29467282
SMAD3 SKIL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22442258 16959829 11306568 10531062 12764135 17469184 12426322 15231748 11691834
BHLHE40 BYSL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
HDAC1 MYOD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11285237 11684023 16713569 20124407
GATA3 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29453984 34026424 26028330 31409898
HDAC3 HDAC9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12590135 10655483 11466315
NLK LEF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12901858 12556497 20194509 24394665
DDX6 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
RHOXF2 VENTX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
SKIL SMAD3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
BYSL STX11 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT31 LMO4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
MAGOHB STX11 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
FRS3 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
PCNA CCND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15681588 7908906 8101826 33961781 7903056 21654808
SOX2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18456656 25482558
BHLHE40 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23423709 21506129 22905217
GRB2 IKZF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 32296183 25416956 27107012
CARD9 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14560001 15692051 17187069
MAPK14 GATA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25056917 27545880
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC MFAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
NFKB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2191300 18490439 19219071
HDAC1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11929879 16189514 16713569 14988403
TRAF1 TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10544141 25241761 20385093 14557256 21903422 14743216 32296183 29748372 11181075 15383523 8702708 8069916 19287455 16713569 9718306 25996949 9500555 33961781
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
HDAC3 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12150997 15811852 15494311
TCF4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12799378 16713569
NFKB1 REL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 27609421 17962807 35140242 33961781 25609649 26186194 15143182
LEF1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16741972 16474850 19351848
U2AF2 SRPK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16189514 16713569 33961781 9472028 23602568 32707033
PAX6 PAX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10804178 11003833 12721955
NFIB NFIX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9099724 35140242 33961781 26871637
NFIB NFIX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9099724
LEF1 NLK â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CRX VPS37C â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRTAP10-7 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
BYSL LDOC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
LMO4 MYOD1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
FRS3 KRT31 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT31 STK16 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
TLE1 HDAC1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 19101520 22439931
HDAC1 HDAC9 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
SRPK2 U2AF2 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
LDOC1 MFAP1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CRX TLX3 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
NFKB1 REL â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
BYSL VPS37B â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP10-8 OLIG3 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP10-8 STK16 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
C1orf216 KRT31 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
MFAP1 PRPF31 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
HHEX KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
MFAP1 U2AF2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HDAC1 PHF12 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
TLE1 LEF1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 9751710 15768032
MORF4L2 PHF12 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
LSM2 PRPF31 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
TRAF1 TRAF2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
NFKB1 BCL2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11313951 11704864 21725609 23178297 23572150
BCL2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11463391 11463392 11532940 11704864 12566895 12667443 14764585 15516985 17446862 19289794 19565474 22039431 23064052 23377657 23430059 23850759 24027568 8929532 9069260 9872359
MYC BCL2 â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 11274345 11283613 11283614 11704864 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
BCL2 TRAF2 â—¼   DOWN_REGULATES ✅ - 8.0 1.0 ACSN 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532
NFKB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 16254192 11567031 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 12032828 19233129 16022909 18761399 18987666 15934930 21224428 16453001
MYC BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8036017 17404573 12695333 24167291 18809243 19201832 16316993 19649202
AR BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17655826 11567031 23160675 20610535
MAPK14 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 29050237 16714293 19336399 11495898
BCL6 PRDM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12165517 20123757 18256039 22406686 20483239 19405121 21674482
NFKB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17673602 10464245 18566231 18341653 11861406 20103608 12894581 17098279 22306268 10409765 19766095 15756023 17407600 18184402 17944672 17008396 15856023 20538607 19263436 16453001
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
TCF4 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19662654 19778454 20459685
LEF1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17360796 10318916 17666529 19620402 19653274 12748295 15798764 17885813
FOS CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 19847806 22550166 15994929 21474819 23157741 15282324 11287611 20188076 9710644 14508521
LEF1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
KLF8 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
TCF4 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
FRS3 GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
FOS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
MAPK14 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 30644418 24424504 21820033 16282370
MAPK14 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 10197981 15241418 14512875 16156666 15520018
PCNA MLH1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20154325 22118461 11274057 23840062
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
NFKB1 MYC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18490439 19219071 21725609 2191300 23178297 23572150
TCF4 MYC â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10391247 11955436 11967263 12051714 15001769 15082531 15576399 16039586 17143292 17936032 19619488 20705860 22290435 22761862 23343194 24023259 25730849 7542250 8666229
NFKB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 12504005 19469019 21790895 19766095 17018379 8289784 18566231 1515224
GATA2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19522008 22951020
PRDM1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12626569 11279146 10713181 12032779
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
TCF4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21533051 19778454 15928669 20133699 18852287 19561604 19662654
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
LEF1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19620402 18202148 17132729 19653274
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
LEF1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
TCF4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
SMARCB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10319872 14559996 14964309 19234532
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
SKIL SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 12764135 23331499 21071413 22442258 11306568 16959829 10531062 12793438 17469184 15231748 11691834 12426322
PRKAA2 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12740371
PAX7 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18854138 15501225 17548510 18508329
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
TRAF2 TRAF1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   ENZYMATIC_REACTION ✅ 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
NFKB1 TRAF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15723831 15041463 19392652 18990758
TRAF1 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
TRAF2 TRAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
SMAD3 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 10890911 21071413 18988627
SMAD3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 11248024 11280774 12226080 16713569 11707452
TLE3 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
NFE2L2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24466341 17640564 18588981 15655294 22951256
NFKB1 IRF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12218129 17018379 16272311
LRP6 FZD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
CSNK1A1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 25301071 23331499 21887268 16890161 27821587 14731402 24794231 25735981 20229235 16341017
NLK TCF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14960582 2861485 12556497 11274345 20194509 18855897
NFKB1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14576180 15517885 20159994 12165860 16619263
NFKB1 TRAF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19343319 17673602 14991743 17018379 9733827 9733516 10823821 11297551
AR RBPMS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535 17721441
AR KLF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19460858 20610535
PRKAA1 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12740371
HNF1B HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10518495 8290348 11585914 16479257
NLK HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14960582 18855897 11274345 20194509
TLE3 LEF1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10485845 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
LEF1 TBXT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10704849 12032083 12234972 11447280 14575694 18948405 15292219 15579438 16139800 14557550 10953028
NLK LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 28.0 1.0 Omnipath 16714285 14960582 23331499 22373574 12482967 12556497 24816797 12901858 11274345 20194509 19623618 18855897
LEF1 TLE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 23331499 15768032 9751710
TLE1 TLE3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10485845 11934263 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
FOXI1 PAX8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15459102 15188428 12538519 15604103
TLE3 TLE5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 11290324 15187083 9783587 11266540 8365415 9887105