Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MTA1 HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23791785 16511565
GRB2 ABLIM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK1 BCL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217079 15225643
MAPK1 BCL2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217079 15225643
HSP90AA1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18266962
BCL2 XRCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18313378
BCL2L1 TCEB2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HRAS BLZF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BLZF1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
CDK4 CDC7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDC7 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDK4 PTK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25733683 18719096
CDKN1A UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7298683 19536131
HNRNPK CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16360036
CHD3 FUBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LNX1 DDX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HNRNPK DDX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
EXOSC5 DDX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0712276105 18334637
KHDRBS1 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
GRB2 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
DHX9 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPA2B1 DHX9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6542847 18519039
GRB2 DHX9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
DHX9 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SPG21 DTX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
GRB2 EEF1A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
EEF1A1 RPL28 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
EEF1A1 TAF9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EEF1G EEF1D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GRB2 EEF1G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
ILF2 EEF1G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EEF1G SNRPD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EEF1G PKN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NCL FBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18292223 0712387105
HDAC7 FOXP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17360565 0700298104
FRS3 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15485655
SHC1 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10704825 5212298
GRB2 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212828 10913131
MAPK3 GAB2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217186 15356145
KAT5 GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
GAPDH PRDX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SMARCD1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
LCK GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
SMARCD2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 SNRPD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PRDX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PKM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RBBP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPL24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HOXC8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 RPLP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 IL2RG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 KHSRP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPL12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RUVBL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPS25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ILF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPL23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
IL2RB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10602027
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
HNRNPA3 HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPL HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001635 23976881
HNRNPA3 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPK HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPA2B1 ILF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001635 23976881
SYNCRIP HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
NOS3 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RBMX HNRNPK â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 8153045 21516116
RASA1 HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221569 9219684
HRAS KRT19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS SMARCB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS MCRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17138645
HSPA8 PSIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA8 PRKAA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 26902588 25961502
HSPD1 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PIK3R2 IGHG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IKZF3 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20676092 22751139
JAK3 IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RB IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RA JAK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RA IL2RB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RA JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RA IL2RG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RG SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 8643566
IL2RG PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10421845
SOCS3 JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10421843 10064597
JAK1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9670964
NOS3 KANK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
KAT5 SNRPD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KRT19 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A STX11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A MCRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A SMARCD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PIK3R2 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
LNX1 RBMX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PARP1 MAPK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
MAPK3 SOS1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MAPK3 PARP1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
POLR1C MKRN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
MKRN3 POLR1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
RHOA NCL â—¼   COLOCALIZATION 2.0 0.8 intact 21281639 8086571
TCHP NME7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PARP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
PIK3R2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499 9651378
PIN1 SOCS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PTBP1 ZMYM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15975576 5217783
SOCS3 PTK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16568091 22547065
RASA1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8155326
XRCC6 RBBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBC RHOA â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5217531 15710384
SYNCRIP RPL24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SOS1 SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9544989 6547749
USP2 UBC â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
BCAS2 SAP18 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ACIN1 HNRNPL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
DDX5 SYNCRIP â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
DDX17 HNRNPL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPA1 HNRNPA2B1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPK SAP18 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
KLHL38 KRT85 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
SAP18 HDAC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 9150135 16189514
JAK1 SOCS3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 10373548 10707961
ACTG1 RUVBL2 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
ACIN1 SAP18 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
BCAS2 SFPQ â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
BUB3 HNRNPK â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EEF1A1 EEF1G â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
HNRNPA3 HNRNPK â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
BCAS2 HNRNPA2B1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RPL28 RPS24 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPL KHDRBS1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MTA1 SIN3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 12920132
CDK4 JAK3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
KDM1A CHD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21937684 19703393
DDX5 CHD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20676135 28977666
CHD3 XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30585729 28977666
IKZF3 CHD4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30760870 12015313
DDX17 SFPQ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34133714 26344197
DHX9 XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30585729 15723802
IKZF3 HDAC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30760870 12015313
HDAC7 RHOA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TOP1 RBM25 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
SHC1 SHC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SIN3B SIN3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
KHDRBS1 SFPQ â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
TAF5 TAF6 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPA2B1 HNRNPA3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DDX17 SAP18 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
FRS3 STK16 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
LNX1 UBC â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
HDAC2 ZMYM2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
RPS2 RPS7 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SHC3 GRB2 â—¼   RELOCALIZATION ✅ + 0.82 0.82 Signor 16829981
RBBP4 MTA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
SHC1 IL2RG â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 8643566
LCK KHDRBS1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 7208262 16107303
MTA2 SIN3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11602581 24981860 12920132
RBBP4 SIN3B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 27705803
TAF6 TAF9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23292512 7597030
HNRNPA1 HNRNPA3 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
ILF2 SNRPD2 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
BCAS2 HNRNPL â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
DDX17 SFPQ â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
GAB2 SHC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HDAC1 SFPQ â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EEF1A1 RPL23 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HSPD1 SNRPD2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
EEF1A1 EEF1D â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
HNRNPA2B1 SAP18 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
EEF1A1 RPS25 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
PIN1 BCL2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11988841 11326318 16713569
CHD4 CHD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24981860 28977666 22939629 32744500 9885572
HDAC2 FOXP3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25609649 19276356
RASA1 GRB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12441060 16189514 16713569
KHDRBS1 HNRNPA1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24514149
KDM1A ZMYM2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ZGPAT RBBP7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19644445 24116224
HNRNPK HNRNPL â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RPL24 RPL28 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RPS2 RPS24 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPA3 SAP18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
FOXP3 IL2 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
MTA1 HDAC2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6613464 18451879
DOK2 LCK â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15831486 25814554 16189514 10799545
IL2RB GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10602027 16189514
PARP1 HDAC2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 34079125 16204234 20596014
BLK SOCS3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
SFPQ SIN3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HNRNPK KHDRBS1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
HNRNPA2B1 HNRNPK â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EEF1A1 RPS7 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
HNRNPK SFPQ â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPA1 SAP18 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
RPL24 RPS2 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPA3 HNRNPL â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CBX3 XRCC6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21888893 34079125
DDX17 PTK6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32296183 31980649
KAT5 FOXP3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19996091 17360565
PARP1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19470756 34079125 16204234 20596014
HDAC4 RBBP4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31040226 10220385
IL2RA IL2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17032757 1993646 16477002
HSPA9 HSPD1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
MAPK1 SHC1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
SAP18 SFPQ â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
GOLGA6A KLHL38 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
NCL TOP1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
SOCS3 YES1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
KLHL38 MKRN3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
GOLGA6A MKRN3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
HDAC1 RUVBL2 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
MTA1 CHD3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12431981 28977666 26344197 24981860 17922035 9885572
BCL2 BCL2L1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DDX17 DDX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DHX9 ILF2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23986595 22863883 22939629
GATAD2A MTA2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ZMYM2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26496610 23752268 28514442 18806873
ZGPAT HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19644445 24116224
HNRNPK RBMX â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
IL2RB JAK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
XRCC6 ILF3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30585729 31536960 21969602
ZGPAT MTA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19644445 24116224
PSMA1 UBC â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HNRNPA1 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HNRNPA1 HNRNPL â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
BCAS2 SNRPB â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HNRNPA3 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
GATAD2A MTA1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HNRNPA2B1 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
KHDRBS1 RASA1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HNRNPL SAP18 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CHD3 CHD4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HNRNPA1 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
EEF1A1 RPS24 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HDAC2 SIN3B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HNRNPL PTBP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MKRN3 PRKAA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
MTA2 MTA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21670149 34026424 24981860 26344197 12920132
KDM1A MTA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21670149 19703393 26028330
MTA2 CHD3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10444591 19703393 28977666 26344197 24981860 22939629 11297506
HDAC1 CHD4 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 26949739
JAK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8536716 11527382
PARP1 HMGB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28190768 29721183 34079125
HNRNPA1 HNRNPL â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MTA2 KDM1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21937684 21670149 19703393
KRT19 TCHP â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
RBBP7 MTA2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
SFPQ TOP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15848144 24981860 9756848
SMARCD1 SMARCD2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
GRB2 KHDRBS1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
RPL28 RPS2 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
HNRNPA2B1 HNRNPL â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HNRNPU SYNCRIP â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
EXOC8 KRT19 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
GATAD2A HDAC1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
KRT19 KRT85 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CDK4 HSP90AA1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
GEM MKRN3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
HNRNPA2B1 HNRNPL â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
MTA1 CHD4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21670149 24440720 28977666 26344197 12920132 24981860 32744500 26028330 9885572
MTA1 MTA2 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CBX3 CHD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21888893 28977666 34079125
HDAC1 CHD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28977666 22939629 26496610 9804427 23752268 20585571 11784859 17827154 28514442 27068747 9885572
DDX17 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15298701 16189514 19995069 20663877
HDAC1 DDX5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19995069 20022962 17369852 15298701 20663877
ILF3 DHX9 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12946349 22751105 22939629 23986595 31536960
SHC1 IL2RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10602027 16189514 8294403
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
GATAD2A HDAC2 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MKRN3 TCHP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
HNRNPL SFPQ â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
EEF1A1 RPL12 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
RBBP4 SIN3A â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
MTA1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21670149 34026424 24981860 16511565 22939629 26496610 9885572 27098840 26344197 21258344 10840944 14722073 26028330 12920132 33264408 17922035 28514442 16189514 26949739 18451879 11146623 23752268 20585571 29997244
HDAC1 CBFB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
CBFB SIN3A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
CDC7 PSIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7231784
PKM CDK4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDK4 PRDX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11986303
HSP90AA1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
RPS2 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EEF1A1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PKM CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ING5 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A RBBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KAT5 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17671089 20351180 16601686
HDAC2 CHD3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28977666 24981860 22939629 9804427 12493763 23752268 17827154 12198550 30737378 26949739 9885572
MTA2 CHD4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21670149 19703393 28977666 12920132 26344197 24981860 9790534 22939629 25247294 20693977 32744500
HDAC2 CHD4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21670149 28977666 26344197 24981860 21258344 9790534 22939629 11003653 9804427 12493763 23752268 32744500 30737378 10545197 26949739 9885572
PARP1 CHD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20693977 26565020
LCK DOK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25814554 10799545 16189514
NUDT21 EEF1G â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LCK GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11572860
PRKAA1 GAPDH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18183946 26626483
GATAD2A RBBP7 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
JAK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8536716 11527382
SHC3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16729043 12242309 16829981
RASA1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12441060 16713569
GRB2 IKZF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 32296183 25416956 27107012
SIN3A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12724404 24981860 14593184 26496610 11102443 17827154 10220385 14647463 9885572 15695521 12398767 26344197 21258344 9804427 16331260 12091390 9150133 11602581 10640275 12920132 9790534 17643391 12943729 19182791 25314079 12374985 28514442 26949739 10444591 11931768 11171972 17956988 12453419 15451426 23752268 11784859 18059533 20585571 9520398 11118440 17962807
KDM1A HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21937684 34031383 21670149 19703393 24981860 16079794 26344197 21258344 20164337 9804427 32882276 12493763 11102443 12032298 23752268 28667074 26949739 34050636
MTA2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10444591 20714342 19703393 18451879 12920132 26344197 21258344 31980649 24981860 22939629 12493763 11102443 19686092 23752268 11297506 30737378 26949739
PRKAA1 HDAC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21892142
HRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
IKZF5 IKZF3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 10978333 25416956 28514442 16189514
LCK JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278738 17570479 16189514
RHOA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
RHOA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK3 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15930121
SHC1 NUDT21 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TOP1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15247263 15848144 34079125
PIK3R2 SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21653832 16456001 10068651
PKM PIN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SFPQ PTBP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8449401 15975576 17507659 16713569 10653975 11514619
RASA1 XRCC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SIN3A RBBP4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9651585 11602581 24981860 21258344 12453419 15451426 9150133 12943729 27705803 9150135 11118440
SIN3A RBBP7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17255935 9651585 24981860 12453419 15451426 26186194 11784859 27705803 28514442
KAT5 RUVBL2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RBBP7 SIN3A â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
GATAD2A RBBP4 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
EEF1A1 RPL24 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
SOS1 HRAS â—¼   GTPASE_REACTION ✅ + 0.9 0.9 Signor 23132018
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
BCAS2 SNRPE â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
BCAS2 SNRPD2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GRB2 SOS1 â—¼   RELOCALIZATION ✅ + 0.9 0.9 Signor 23452850
RBBP7 SIN3B â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
SHC1 SOS1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CHD4 MTA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CBX3 STK16 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CHD3 MTA1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CHD4 GATAD2A â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CHD3 HDAC2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
ACIN1 SAP18 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
PKN1 RHOA â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CHD3 MTA2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
ILF2 ILF3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
JAK3 IL2RG â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 27742835 7973659 7973658 16189514
CHD3 GATAD2A â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CHD4 MTA2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CBFB TCEB2 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
FBL RPS7 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CHD3 HDAC1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CHD4 HDAC2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CHD3 RBBP7 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
EEF1A1 RPS2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
IL2RB IL2RG â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
MTA2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6613464 18451879
SOS1 HRAS â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 17084389 5219305
TAF5 TAF9 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 17355863 23292512
CHD3 RBBP4 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RBM25 SNRPB â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RBM25 SNRPE â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RBM25 SNRPD2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CHD4 RBBP7 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CHD4 RBBP4 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CHD4 HDAC1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
EEF1G EFTUD2 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
FBL NHP2 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
IL2RG IL2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 16477002 10662798 8006584 8049354 22446627 11418623
STAMBPL1 UBC â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
HDAC2 MTA1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
MTA1 RBBP7 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
EFTUD2 SNRPB â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
HDAC1 MTA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
ILF3 ILF2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 17389650 11739746 26472337 29395067 22939629 21969602 26186194 20808282 23986595 28514442 16189514
HDAC1 SIN3B â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
HDAC2 KDM1A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SMARCB1 SMARCD2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
MTA2 RBBP4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
RBBP4 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 34518534 11302704 11102443 27705803 17827154 10734134 10220385 9885572 10471499 26344197 21258344 12091390 9150133 16713569 11602581 12920132 20127688 9790534 17643391 11470869 19686092 12943729 9150135 28514442 16189514 27068747 10444591 19703393 11171972 15451426 23752268 20585571 9520398 11118440 31435636
RBBP7 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 17255935 22939629 26496610 11102443 27705803 9885572 10471499 26344197 21258344 12920132 9790534 19686092 9150135 28514442 25885317 10444591 19703393 15451426 26186194 23752268
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
SIN3A HDAC2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12724404 16254079 12082111 24981860 17827154 22493095 9885572 12398767 26344197 21258344 9804427 12493763 14749338 12091390 12943729 25314079 26949739 12453419 15451426 23752268 9150134 18059533
CBX3 HIST1H1E â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SOCS3 TCEB2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HRAS RASA1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
GAB2 GRB2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
HDAC2 MTA2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CDK4 CDKN1A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
UBC USP2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
EFTUD2 SNRPD2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL12 RPL28 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL24 RPL28 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL28 RPS7 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL28 RPS24 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
HRAS SOS1 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
SHC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12213123 8491186 8950973 9927207 9733714 8112292 10356320 11370743 32062451 8294403 16371368 22057045 9045692 9032244 8995379 7514169 9175774 9541596 8663178 7629070 9019162 7597091 7798267 9544989 9488479 8940013 10570290 15812354 11792427 8621719 24430869 7650032 11453982 16713569 7516467 10477741 8662733 11302736 26551075 9254595 7559490 12441060 8662998 8235613 12485888 28690151 16520382 8939605 11505033 9129019 11707405 15888547 8647288 7524086 25416956 24189400 11827484 12149229 8195171 21725358 9020193 10049786 9797459 9886492 33961781 9126968 8626525 7537740 12577067 11964172 12898421 8810340 22974441 19380743 9434624 10080542 9083103 21706016 15688026 7535773 31980649 8561895 7744881
RPL28 RPS2 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
BCAS2 EFTUD2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EFTUD2 SNRPE â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPLP2 RPS24 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HDAC1 MTA1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MTA2 RBBP7 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPL12 RPS24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPS24 RPS7 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPL12 RPLP2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCB1 SMARCD1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SNRPB SNRPD2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SNRPB SNRPE â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MTA1 RBBP4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPS24 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPL28 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL24 RPS7 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL24 RPLP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL24 RPS24 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL28 RPLP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL12 RPS7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL23 RPLP2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL23 RPS7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL28 RPS25 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP2 RPS25 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP2 RPS2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP2 RPS7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS2 RPS24 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS24 RPS25 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SNRPD2 SNRPE â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL12 RPS25 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL24 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS25 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPL24 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL24 RPS25 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL24 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EEF1D EEF1G â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GRB2 SOS1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS2 RPS25 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS2 RPS7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS25 RPS7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF5 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
RHOA ACTG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
BCL2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11463391 11463392 11532940 11704864 12566895 12667443 14764585 15516985 17446862 19289794 19565474 22039431 23064052 23377657 23430059 23850759 24027568 8929532 9069260 9872359
BCL2L1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18835031 14980220 26186194 11583631
MAPK3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9115213 10669763 9735392 11323415 21785723 9738012 10677502 23272207 25826088
MAPK1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9115213 10567572 12039864 10669763 15225643 11323415 21785723 9738012 11337027 10677502 23272207
YES1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18479465
CDKN1A CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 23443559 15169570 18850315 9658399 16962592 15232106 9632134 16189514 8622677 15695403 20102411 8242751 9464540 23007395 7626805 9106657 12383116 30193583 17556661 23543736 8756624
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
HDAC4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18632985 18850004
MAPK1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20519948 19364816 28368408
DDX5 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15298701 17369852 20022962
EEF1D EEF1G â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 16169070 32814053 16189514 30021884 9407120
FOXP3 IL2RA â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12522256 17237765 17449799 21411734
FOXP3 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 25567984 23275607 22806628 21458306 17028180 16873067 21955384 17586580 23954131 17922010 20429413 18324310 19172156 17416586 22579476 18779564 17430097 21654845 17632414 11483607 18759924 19564342
FOXP3 IL2RA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23144749 20554955 17028180 18606654 15466453 21036387
LCK FOXP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 28757603 26441996 30011797 24155921
FRS3 GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
FRS3 SOS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
GRB2 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
SHC1 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
MAPK3 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12008033 15356145
GRB2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 16371368 25416956 21706016 15143164 10391903 19172738 10913131 11027663 9973481 10973965 20936779 10068651 11882361 32296183 16199887 24737791 15010462 19523899 16253990 19380743 31515488 11782427
MAPK1 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12008033 15356145
GAB2 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9973481 10982827 18950707
GAB2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8995358 10704825
SOS1 GRB2 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 8810325 33961781 8695800 7510700 8626525 34407391 16520382 10570290 16906159 16893902 7642581 8816480 9447984 12577067 11964172 8112292 8493579 7664271 16713569 7516467 19380743 9009162 10207103 17474147 10477741 32062451 7629138 21706016 20473329 19323566 9872323 32203420 7514169 21988832 28166272 28514442 9716598 11997436 9344843 15192046 10716926 8479541 14679214 8943292 31980649 7629168 7559490 9478994 7527391 8188688 11960376 10025673 11726515 7773779 10319320 9569023 9797459
GRB2 SHC1 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
LCK GRB2 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 8478617 8986721 9438848 9738502 9751747
HRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
GRB2 SHC1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
SHC1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 198.0 1.0 Omnipath 8808684 9083103 8551221 9126968 8621483 25416956 9252386 8524223 7535773 8662998 11302736 11827484 8995379 9541596 9175774 10207047 7717978 17673906 7744881 11505033 10523831 24189400 9927207 7650032 8810340 9045692 23178716 19531499 15812354 9129019 10356320 12485888 9461587 8114695 7514169 9566877 8939605 16371368 15341520 7529871 10891441 10749687 7524086 26645482 8491186 10592173 10049786 9171350 11707404 7537740 15688026 8663178 19380743 11782427 9544989 16436051 9434624 16713569 21725358 11964172 17314098 11792427 8195171 1465135 12213123 8647288 12955078 10477741 11707405 12577067 9199344 10080542 8112292 7760801 10570290 11997181 7798267 16520382 10961885 8950973 21706016 9448048 8662733 11370743 8051109 9733714 8621475 9254595 8294403 10748054 8621719 8940013 12441060 22057045 7505797 24737791 20697350 9886492 18174162 18273058 8235613 7963520 7523859
GRB2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17496910 16713569 17673906 11352655
GRB2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 145.0 1.0 Omnipath 9544989 9872323 7642581 15746962 11726515 8621483 23334917 16520382 11997436 21706016 10359574 8950973 7664271 16713569 16893902 16906159 21988832 19323566 9009162 10716926 11964172 7629168 9815779 10592173 9716598 8647802 28166272 7773778 7773779 18778683 8188688 10319320 8810325 9344843 23452850 11960376 8816480 10025673 7510700 8940013 12955078 9697839 12345678 10477741 8493579 8943292 12577067 7862167 9199344 8112292 7898932 10207103 8695800 19531499 10570290 7760801 20005866 19380743 9447984 8235613 8479540 7527391 14679214 8479541 17474147 7514169 7629138
GRB2 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10467411 20936779 21988832 7537265 9872323 8576157 11960376 11278465 9045636 21706016 16713569 12112020 7799925
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
PRKAA1 HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27010499 18184930 21892142
MAPK3 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11259409 16564677 11231586
HNRNPK KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21988832 22365833 31413325 16713569 12370808
PIK3R2 HRAS â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
HRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS SOS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
RASA1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 10769036 11389730 23331499 18829532 7628625 9219684 10592173 8663024 16713569 26721396 8360177 8537347 1904555 10394594 2833817
SOS1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12628188 10208427 16713569 10913276 23331499 18454158 15507210 10592173 17673906 17496910 26721396 20133692 19141281 23132018 11560935 9447984 9690470 17084389
HSP90AA1 SHC1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 16187797 15284455 17646646 16969069 17372273 17712310
HSP90AA1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12124224 11988487 11425855 11744239 9580552 12676772
JAK1 IL2 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RG â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RB â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IL2 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RB â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RG â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 15265897 16477002 10807786 19528259 19833085 7521688 17371980 8049354 15563472 18758473 10662798 15289500 23331499 26755705 8683106 23180781 12095053 11418623 6164929 9625766 24829413 1825141 8006584 16799562 7829965 8568232 10820393 7512720 23650441 20856220 7681595 10849428 22224781 1631559 16212621 21840487 26192618 2965306 8260650 23124025
IL2 IL2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 6815536 3095922 15265897 12649439 16477002 15933202 1940342 17032757 15178252 8260650 3116143 8894436 1993646 8580082 8960125
IL2 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 8568232 3095922 15265897 16477002 11035066 3098894 15933202 1940342 15178252 8260650 3116143 22446627 8006584 8049354
JAK1 IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8568232 15265897 11886175 15933202 15178252 1545122 8260650 3116143 8006584
IL2RA IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15933202 15265897 8568232 8260650
JAK1 IL2RB â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
IL2RG IL2RB â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
IL2RG IL2RB â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
JAK1 IL2RB â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
SOCS3 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10373548
JAK3 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 7693677 16189514 10825200 7973659 9553136 7973657
LCK IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10214954 2047859 10602027 18348982 16189514 12200137
JAK1 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 9774657 7973658 8700888 12133952 8643566 10373548 7499411 8041779 7973659 9553136 7973657
IL2RG IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 8568232 15265897 7514277 10903799 11886175 8026467 15933202 7681595 15178252 1545122 8260650 16189514 11851401 8006584
IL2RB SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8294403 8700888 8643566 10602027 16189514 24737791
IL2RB IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 8568232 15265897 7514277 10903799 11886175 8026467 15933202 7681595 15178252 1545122 8260650 16189514 11851401 8006584
IL2RB SOCS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10373548
JAK1 IL2RG â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10358772 10426994 10485906 10807786 10820393 10849428 10856136 11160275 11371360 11867689 11870632 11907067 12095053 12223527 12244150 12401408 12496409 12811837 12818165 14607946 14610620 15289500 15536084 15563472 16081783 16212621 16243976 16413922 16713974 16785506 16799562 16815076 17371980 17398124 17404308 17459805 17485448 18250477 1825141 18758473 19528259 19833085 19913445 20007590 20184663 20406969 20510870 20856220 21307131 21469115 21840487 22224781 23124025 23390297 23650441 24030977 24091328 24751819 24829413 25582338 26755705 27216177 2965306 6164929 7512720 7521688 7523571 8683106 9625766 9834059
JAK1 IL2RG â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10358772 10426994 10485906 10807786 10820393 10849428 10856136 11160275 11371360 11867689 11870632 11907067 12095053 12223527 12244150 12401408 12496409 12811837 12818165 14607946 14610620 15289500 15536084 15563472 16081783 16212621 16243976 16413922 16713974 16785506 16799562 16815076 17371980 17398124 17404308 17459805 17485448 18250477 1825141 18758473 19528259 19833085 19913445 20007590 20184663 20406969 20510870 20856220 21307131 21469115 21840487 22224781 23124025 23390297 23650441 24030977 24091328 24751819 24829413 25582338 26755705 27216177 2965306 6164929 7512720 7521688 7523571 8683106 9625766 9834059
JAK1 IL2RG â—¼   ENZYMATIC_REACTION ✅ 70.0 1.0 ACSN 10358772 10426994 10485906 10807786 10820393 10849428 10856136 11160275 11371360 11867689 11870632 11907067 12095053 12223527 12244150 12401408 12496409 12811837 12818165 14607946 14610620 15289500 15536084 15563472 16081783 16212621 16243976 16413922 16713974 16785506 16799562 16815076 17371980 17398124 17404308 17459805 17485448 18250477 1825141 18758473 19528259 19833085 19913445 20007590 20184663 20406969 20510870 20856220 21307131 21469115 21840487 22224781 23124025 23390297 23650441 24030977 24091328 24751819 24829413 25582338 26755705 27216177 2965306 6164929 7512720 7521688 7523571 8683106 9625766 9834059
IL2RG JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 7973658 7721895 8580378
IL2RG JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 7973658 7973659 18445337 10856136 16189514 10629052 15621723 7973657
JAK3 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11641425 19901323 20135364 17259970 12207328 10825200 11909529 15659558 12559972 9553136
JAK1 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9774657 15021914
JAK1 SOCS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25682267 10950967 16459330 10707961 10373548
JAK3 SOCS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15385932 10373548
XRCC6 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
PTK6 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 10913193 19304789 16179349
MAPK1 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18691976 12478298 19664995 20068231
PRKAA1 KPNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15342649 17919121 27303922
MAPK1 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 8506364 7499846 8618896 15967991 8226850 8626561
MAPK3 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 8506364 8618896 8226850 7597029
LCK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 9446569 17389395 18578522 10921922 10482988 10764799 18452278 20068231 18669648 12522270 9685404 10896916 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
LCK SOCS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12783885 15173187 16352613
LCK PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11526404 15032589 14583609 23109003 8397196 10488096
LCK RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 11389730 1850098
SHC1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10996427 23584453
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 10197981 8816480 9922370 8626428
MAPK1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23597856 26637332 16627622
MAPK3 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 29145629 7478566 23331499 8816480 7739560 17570479 9922370
PRKAA1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10376603 12446767 11729179 16043647 11696579 16126727 12791703 24379783 19131647 18303014
PARP1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 20875401 15911331 15848144 14699148 15247263
RHOA PKN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8571127 12773565 16189514 9446575 10619026 9535835
SOCS3 RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 11331873
SFPQ TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 9756848
SHC1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 9544989 8631299 8621483 8950973 10891441 10783152 9278309 17673906 9344843 8294403 8021500 10025673 7520523 12955078 12577067 9199344 19531499 7760801 10570290 19380743 8235613 10675333 8114695
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368