Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PLD1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP3K20 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11836244
VIM NEFL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
NEFL KRT19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
C2ORF15 PKN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AR MBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 7657701
H3C2 SNAI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7903691 20389281
H3C2 KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
EGFR H3C2 â—¼   COLOCALIZATION 2.0 0.8 intact 5216105 12577067
NCOA2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
H4C6 KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
NCOA2 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
H3C14 KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
THAP3 PKN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H3-3B KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
AKAP9 GOLGA2 â—¼   COLOCALIZATION 2.0 0.8 intact 7234073 19242490
MAPT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0709180105 18292230
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
PKN1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1218925110 23223530
CASP3 AKT1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
RHOA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15884057 11748077
RHOA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PDK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK12 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA1A APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEFH APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PGAM1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PKN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AR APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16987234
HSP90AB1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21730179 1105160108
NCOA2 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12588987 5216126
AR YWHAH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19996220 8009645
AR KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
AR KDM4C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23698634 20610535
AR RHOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 23209612
AR TNFRSF1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7476976 20610535
AR SMYD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 24174655
KDM4C AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17277772 29207681
ARHGEF2 RHOB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16917499 18287519
VIM BECN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1225967 23112296
BECN1 PKN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BLZF1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
FOXO1 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19050291 15565601
CEP70 CCDC85B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CCDC85B PKN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CCNJL PKN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK1 PKN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 31981797
COG6 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DYDC1 USHBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EEF1G PKN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF3F FBXO32 â—¼   COLOCALIZATION 2.0 0.8 intact 6613251 18354498
TRAF1 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
IKZF3 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GOLGA2 IKZF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PKN1 HOMER3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
HSP90AB1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KCTD17 PKN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KRT19 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
ZNF581 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A STX11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A SSX2IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SNAI1 KDM1A â—¼   COLOCALIZATION 2.0 0.8 intact 7903691 20389281
PKN1 KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
USHBP1 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRT19 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
USHBP1 KRT19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MAP2K3 MAPK11 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8622669 7535770
MAP2K3 MAPK14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8622669 7535770
MAPK14 MAP2K6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255949 5219578
MAP2K6 MAPK14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8622669 7535770
MAP2K6 MAPK11 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8622669 7535770
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
MAPK14 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20626350 15632108
PDPK1 RHOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12783890 10753910
PDPK1 RHOB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12783890 10753910
PDPK1 RHOC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12783890 10753910
PDPK1 YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12177059
ZNF581 PKN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZNF232 PKN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PKN1 PPP1R14A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12563012 10924361
TRAF2 RUVBL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
USHBP1 SERTAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SERTAD3 USHBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TUBB TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VIM TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EGFR TUBA1A â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ASH2L HIST2H3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
HIST2H3C RBBP5 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
RHOB PLD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
TRI27 PKN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 33251042
VIME BECN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31272261 23112296
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HAUS1 COG6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
COG6 SPAG5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
COG6 PKN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB FARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
HIST2H3C KMT2A â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CA186 PLD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
UPAR ARSA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
UPAR PKN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CA186 PKN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MAGAA NCOA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 26496610
MAGAA PKN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AKT1 MAPK14 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
RHOC RHOA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 31871319 31980649
ARHGAP5 RHOA â—¼   GTPASE_REACTION ✅ - 0.83 0.83 Signor 32203420
CDK1 CDC25C â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 8119945
CDC25C CDK1 â—¼   DEPHOSPHORYLATION ✅ + 0.83 0.83 Signor 19574738
HIST2H3C WDR5 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
TUBA1A TUBB â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
PARK2 TRAF2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
PKN1 VIME â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25416956 9175763 16189514 16713569
RHOB PKN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 34079125 31871319 34187934
AKT1 FOXO1 â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 21798082
AKT1 FOXO1 â—¼   RELOCALIZATION ✅ - 0.85 0.85 Signor 18423396
PKN1 TRAF2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14741690 32296183
PKN1 CC85B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16189514 16713569
AKT1 AR â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
KDM1A SNAI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
WDR5 PDPK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 27705803
HSP90AB1 MAPT â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDC25C YWHAH â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PKN1 NFL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32296183 16713569 8621664
PKN1 ACTN1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11802708 16189514 9030526 16713569
BECN1 AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 29669822 23112296
AKT1 PDK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 34278744 27505672 27166089
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
TNFRSF1B TRAF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
RAF1 YWHAH â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AKT1 FOXO1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
KRT34 MKRN3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
PNMA1 ZNF581 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
PKN1 AKAP9 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32296183 10358086
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
EGFR HSP90AB1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PDPK1 PKN1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10792047 10764742 16189514 10753910
SPRR2D PKN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PKN1 ZNF282 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
VIME NFL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 15383276 31944090 16713569 28514442 34079125
KDM4C H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 29207681 18022353
MAPK14 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278789 10806218 12917630
PDPK1 AKT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11438723 11313365 23397142 11278835 14500673 26264872 32876514 27563096 26256536 9368760 12149249 11445557 31467278 11825911 10226025 21775285 10698680 22569334 16189514
AKT1 EEF1G â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AR MID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24913494 20610535
AR KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 16079795 22052438
AR CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22038727 20610535 23554843
PKN1 ARHGEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14970201
EGFR CDK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18271526 15657067 24658140 31980649 23956138 25402006
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
PKN1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21749319
PKN1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12560069
SNAI1 KDM1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20389281 21300290 26186194 20562920 23011797 25639869
PKN1 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11238375 17145710 12761180
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PKN1 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 17251915 12761180
PKN1 PGAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12189148
PKN1 PGM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15378030
PKN1 PPP1R14A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17301291 10924361 15003508
PKN1 SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15833848
PKN1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9175763 16713569
SNAI1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12632084 19538137 17273560
NEFH VIM â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
KRT34 ZNF581 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
ZNF581 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PKN1 RHOA â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
YWHAH RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8005785 11697890
MAP2K6 MAPK14 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
MAP2K3 MAPK14 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
AKT1 PDPK1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
AKAP13 RHOA â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
WDR5 KMT2A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
AR NCOA2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ASH2L KMT2A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A WDR5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A RBBP5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
APBB1 APP â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
TRAF1 TRAF2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RBBP5 WDR5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RHOA PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11102529 12593858 9565577 11311142
MAP3K20 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 11836244 14697338 11042189
KDM1A H3C2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
MAPK14 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20626350 11278789
KDM1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16223729 20210320 18343668 20228790 15620353
KMT2A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12453419 20210320 24680668 29897600 31485071 20541251 24235145 20452361
KDM1A H4C6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
KDM1A H3C14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
KDM1A H3-3B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
AKT1 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12588998 12529330
AKAP13 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19696020 11696353 12423633 32203420
PDPK1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11687500 11747822 12670391 15802604 17680028 18802401 19109239 19122654
AKT1 FOXO1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
AR AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20589722 11278645 17896924 18687691 22740037 12621049 12063252 22970326
PDK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 12176337 15743829 12682057 11445557 15899889 12149249 10833263 15718470 11278835 10226025 11087733 14500673 16341064 19897009 9368760 24012393 11825911 9512493 9736715 11313365 9868760 15364915
PDPK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 156.0 1.0 Omnipath 15505410 12538620 12176337 19951971 24352480 11752451 19401591 11369519 10698680 10601311 15718470 24950409 20481595 24169049 10570282 16798838 14993273 11500365 9368760 19844585 17680028 7637810 9169478 26256536 7722458 9094314 12750173 11438723 18802401 9252186 23331499 18456494 9104825 10592173 16189514 20361045 18988627 11278835 20163786 20333297 20041157 12808134 19602588 8630736 10207050 11241670 10438924 9868760 25912234 20153221 25582703 11445557 21775285 12149249 14666721 18596232 9512493 23397142 11809791 12167717 21798082 16033886 10679787 16787925 29562639 15550174 21071413 8978681 10833263 19203586 10226025 26937223 14500673 20161206 11136732 11825911 11042193 9642236 22569334 18662999 9736715 12242303 11313365 11598012 11134526
PPP2R5D AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18039929 19216069 10026142 10995457 18042541 20452955 18559511 18588945 16680151 16406523
CASP3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17544405 12124386 10579725
AKT1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20856200
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
AKT1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 90.0 1.0 Omnipath 21440011 10358014 11756412 10358076 31308176 20452955 21798082 11410590 20398329 11311120 11544290 28279977 10217147 15132996 23331499 19216069 11237865 20214616 11463845 16076959 11030146 12228231 9829964 18951090 23180781 17570479 10102273 18593906 17646672 16680151 12456685 18423396 18985696 18988627 17962350 30728292 16670091 18786403 14664696 25241761 16341064 11980723 10358075 2984676 13679577 12560069 10377430 11251083 17680028 2987962 17254970 11864996 20041807
AKT1 YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17470458 18349820 29861848 16210317 21601007 17570479 11404460 22155408 12621049 14555644 11156376
AKT1 EIF4B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18836482 17570479 25749412
AR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15305378 19318561 21613411 19258514 15650253 17242169 18692155 15288768 11556855 20610535
NCOA2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9717843 12588987 15684378 14593076 24239470 15563469 18780293 12810069 16713569 10601285 14966121 10935543 10454556
MAPK14 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 30644418 24424504 21820033 16282370
CASP3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8626669 9535906 16713569 9208847
KDM1A AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17277772 16079795
CDK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 26573794 12569365 22275373 25704883 17043241 23321516 9725910 24480624 21799006 24424504 28062857 21820033 25950519 28415597 27450452 25691442 21782001
PA2G4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 15583694 9565586 12165860
AR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18358509 12534934 22260327 15288768 18951974
AR FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18391971 17202144 16713569 12482965
ARHGAP5 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 32203420 9407060 10592173 8537347 12842009
ARHGEF2 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9789025 22072711 32203420 9113980 9641915 10592173 9857026 20810787 16189514 24525234 11149925
ASH2L WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MAPK14 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 14970175 33176141 29414778
CASP3 EIF4B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11274152 10672017
CASP3 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11423904 10469173 11514563
CASP3 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12888622 16606369 22535953 11162250
CDK1 CDC25C â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 1075565 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17568790 17596790 17660363 18073536 18414028 18543256 18590585 18786381 18995830 19652693 19686080 7575488 9892021
CDK1 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17349584 17110335 17303408 18073536 1075565 11836499 15279786 8348613 7575488 20668692 24710276 9733650 12036951 20068231 8440392 12742231 32075732 16189514 9141461 16123593 18669648 19652693 18590585 9585407 12814430 10864927 10373560 18691976 11313986 12124778 18786381 17660363 18272572 8119945 15917306 27038604 9268380 17596790 28396830 17568790 19350548 16964243 10037602 18212344 12478465 12766774
MAPK14 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 15150265 10744722 9836640 9543386 12941695 20068231 9278512 10681541 16189514 15791647 11551930 9278511 11333986 15629715 10557092
CDK1 GOLGA2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 15678101 7737117 11238451 11306556 18167358 1902553 9150144 10679020 9753325 11285137
CDK1 GOLGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 19007248 19691289 18691976 9753325 20068231 10769027 16964243 18669648
CDK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 31980649 8360196 23956138 15901825 28150246 18271526 15657067 24658140 25402006 15302935
CDK1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 82.0 1.0 Omnipath 19007248 16565220 17081983 22120848 18767875 9168797 19690332 27603133 15766329 12761892 19413330 21465480 19664995 16260496 19415658 25960391 18578522 20068231 15713670 17570479 24073199 18491316 18669648 18691976 17287340 15345747 20068230 19651622 20058876 19691289 17924679 16542212 19369195 25184044 18707149 7983050 19584300 16964243 21422740 18212344
CDK1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 18408765 18356527 27035875 19473886 24948874 25590687 23029264 19124971 22280365
PKN1 CDR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9637778 32296183 25416956
MAPK14 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15187187 18039929 19138820 7535770 12738796 17139251 16932740 23397142 16785992 11274345
MAPK11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15187187 18039929 12738796 16932740 11274345
FOXO1 FBXO32 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21798082 20079455 15109499 17540700 15125842
HESX1 NPPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16909307 12023302 20874724 15081310 11847222 9295358 19799869 16166646
TRAF2 MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
TNFRSF1B MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
TRAF2 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
MAP2K3 MAPK12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 11242034 11062067 21614932 12738796 11274345 11238375 19413330 18083107 18855897
MAP2K3 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 12589052 11279118 17081983 20213747 7914033 18767875 17322306 23602568 8622669 18855897 19690332 23904011 9162092 11426938 15592455 18083107 7997261 12384504 15735649 18291705 23331499 17389395 7535770 19534553 7839144 21071413 16083285 21614932 20068231 12738796 16189514 17255949 18669648 16153436 14970210 26186194 16407200 11242034 18691976 18088087 11304531 15972258 10781613 17192257 18586681 10734320 19651622 7592586 16157584 19369195 9582275 15674326 9528766 7693711 9841871 12758252 11309380 7750576 15212693 15659558 11274345 15735648
MAP2K3 MAPK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18291705 11704645 23331499 11242034 19369195 21614932 14724572 12738796 11274345 18083107 18855897
TRAF2 MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
TNFRSF1B MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
TRAF2 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
PKN1 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238375 17145710 12761180
MAP2K6 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 96.0 1.0 Omnipath 10480932 19901323 17081983 7914033 9362518 18767875 17322306 8622669 18855897 16342939 16497976 15592455 8974401 7997261 15735649 18291705 23331499 8626699 21071413 16083285 21614932 18452278 12738796 20068231 9808624 11727828 16189514 18988627 17255949 9790884 16153436 18669648 26538579 14970210 16282370 11242034 18691976 18088087 11304531 15972258 10781613 17192257 18586681 10734320 20551513 19651622 15212693 7592586 16157584 21402774 9582275 15674326 9528766 7693711 12758252 11309380 7750576 17255097 17016520 15659558 11274345 15735648
MAP2K6 MAPK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18291705 23331499 9362518 11242034 8622669 9430721 21614932 12738796 11274345 11727828 9790884 18855897 8621675
MAP2K6 MAPK12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 23331499 10848581 11010976 11242034 11062067 21614932 12738796 11274345 11238375 19230643 19413330 18083107 18988627 9790884 18855897
MAPK12 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 76.0 1.0 Omnipath 9832145 19562805 12387894 9546672 19413330 15632108 1330687 19415658 15302935 9353289 9202310 20068231 9565682 11181841 7566346 12435421 17287340 9771888 17078951 19651622 9735171 10620503 11104762 12226093 9199504 18510355
PKN1 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 9565682 11181841 9614189 9832145 11104762 12387894 12226093 19562805 12714590 19857203 12435421 9546672 9771888 19413330 9199504 8999860
PKN1 MARCKS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 44.0 1.0 Omnipath 17081983 20166139 18767875 17322306 11162562 19413330 19664995 18578522 91317794 20068231 11930178 16116087 18669648 17114649 8557118 17287340 14963034 19651622 20058876 18707149 18212344 15708490
PDPK1 PKN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 10753910 10467162 10792047 16189514 26296974 10764742 18669648
RHOC PKN1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14514689 21351730 10619026 9988689 18006505 24128008
RHOA PKN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8571127 12773565 16189514 9446575 10619026 9535835
PKN1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15849194 11733498
YWHAH RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12801936 11697890 8702721 17979178
WDR5 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
TRAF2 TNFRSF1B â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23070005 23850759 24378531 9379049 9582321
TRAF2 TNFRSF1B â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23070005 23850759 24378531 9379049 9582321
TNFRSF1B TRAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18429822 9168896 8548810 9162022 16713569 7859281 8069916
TNFRSF1B TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 8702708 10206649 16713569 8069916 7544915 18161752 14743216 9162022 15572357 18671942 9461607 8855313 11907088 8710854 11112773 15485837 9168896 8548810 7639698
TRAF2 TRAF1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   ENZYMATIC_REACTION ✅ 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
TRAF1 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372