Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
XRCC4 CSNK2A1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15385968 5217205
CSNK2A1 HIF1A â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17382325 5219810
ENO3 HSPB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 26465331 0133994
LRRK2 FANCM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
PGM1 HSPB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 26465331 0133994
S100B S100A1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TERF2IP TERF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605303103 16880378
PGM1 TPI1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
WRN ENO3 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
RAD18 PGM1 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
LRRK2 LDHA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
XRCC4 PGM1 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
RAD18 ALDH6A1 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
ALDH6A1 TPI1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
DCLRE1A PGM1 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
RAD18 PAK1 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
S10A1 PGM1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 8894274 16189514
S100B PGM1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 8894274 16189514
POT1 TERF2IP â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
TERF2IP TINF2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
POT1 TERF1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
FANCM PGM1 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
POT1 TINF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
S100B S10A1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27107012 32296183 9925766 32814053 26871637 21516116 26264872 25416956 16189514 29997244 10913138
HIF1A GBE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020
S100A1 PGM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8894274 16189514
S100B PGM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8894274 16189514
PKN1 PGM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15378030
SHPRH RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
TERF1 TINF2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
S100A1 S100B â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
HIF1A ARNT â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 12391259 10085255 16954218 7836384 17916562 26496610 8663540 34592152 14764593 20603618 14668441 21512126 11606485 26350169 9079689 24056783 19845609 27684187 11782478 19168635 23363003 26160453 28628118 15850782 17197389 21620138 15833858 23086815 24434214 20458141 18024476 23458834 12810720 28514442 15347669 9704006 27320910 20562859 11829741 15031145 21435239 20049704 15479785 20932347 12393189 11025203 16861921 9159130 10671489 16520375 15615775 17213817 28205554 23796364 15319539 11593383 19251694 20699359
S100B S100A1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8153045 21516116
TINF2 TERF1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10581025 15383534 28514442 21044950 19487455 33961781 15316005 11701125 26496610 16880378 16169070 15133513 26186194 20811636 17589526 25416956 15181449 28216227
ARNT HIF1A â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CSNK2A1 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16129408 18669648
ARNT HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17213817 8816435 17197389 14764593 12393189 12810720 15319539 23363003 9079689 11829741 15479785 26496610 12391259 17916562 24434214 11606485 20562859 9704006 21620138 11782478 20932347 15347669 8927054 21435239 19168635 9159130 14668441 20049704 20603618
CSNK2A1 TERF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18347021
HIF1A TPI1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A LDHA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15794924 19828020 8089148 9632793 9746763 8955077 9748288 16319523
PAK1 PGM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15378030
TINF2 POT1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
TINF2 POT1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
WRN POT1 â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 11283614 12202749 12545156 15155580 15385537 16449207 17055429 17116323 17550342 17965729 18398454 18524993 18558713 18584027 18809224 19490890 20027199 20064462 20691907 20713526 20818389 21376743 21733352 2191300 21919891 22657828 22743550 23082994 23140366 23161013 23253856 23869868 24036544 24050180 24709898 9618481
WRN TINF2 â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 11283614 12202749 12545156 15155580 15385537 16449207 17055429 17116323 17550342 17965729 18398454 18524993 18558713 18584027 18809224 19490890 20027199 20064462 20691907 20713526 20818389 21376743 21733352 2191300 21919891 22657828 22743550 23082994 23140366 23161013 23253856 23869868 24036544 24050180 24709898 9618481
WRN PGM1 â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
SHPRH PGM1 â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
DDB2 ALDH6A1 â—¼   KO_UP_REGULATES ✅ + 1.05 1.05 PKG 28854368
DDB2 PGM1 â—¼   KO_UP_REGULATES ✅ + 1.3 1.3 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
SHPRH SHPRH â—¼   KO_DOWN_REGULATES ✅ - -4.0 3.99 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368