Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ADRB2 DCLRE1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
BRCA1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR BRCA1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 23422745
ATR DCLRE1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15456891
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
U2SURP DCLRE1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KTN1 DCLRE1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DCLRE1A ERVH48-1 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
DCLRE1A ANXA1 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
DCLRE1A DPP7 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
DCLRE1A DND1 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
ERCC6 MMADHC â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
DCLRE1A PPCDC â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
DCLRE1A PGM1 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
TP53BP1 UBC â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ERCC6 UBC â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
DCLRE1A CERS1 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
PCNA UBC â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
DCLRE1A GALNT3 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
ATR TP53BP1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
DCLRE1A B2M â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
ATM BRCA1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ATR BRCA1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PCNA TP53BP1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
DCLRE1A MT1G â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
UBC UBE2G2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
DCLRE1A SLC16A3 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
DCLRE1A RBM4 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
ATM ATR â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ERCC6 SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
DCLRE1A FEZ2 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
PCNA ATR â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA BRCA1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA ATR â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA BRCA1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM BRCA1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATR ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15510216 10608806 17478428 17124492
ATM DCLRE1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15456891 18848520
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
ATM BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 26927092 17303408 15159397 24746700 12024016 10866324 30197789 12919958 11114888 26745677 26383678 34301763 12427729 11313470 16163361 28035057 20068231 25939603 26320175 17570479 19683496 22743550 10608806 23802008 23847781 21203981 15964794 12183412 12607003 17525332 19996295 15459660 11278964 19651622 21706030 11877377 20952512 10373534 19622773 10550055 27170701 15212693 23704879
ATR BRCA1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 26927092 17478428 24746700 15159397 17531442 10866324 18677104 19622404 15798197 19793801 20860841 16713569 11114888 23422745 20936109 16322207 19282663 20068231 17116885 17582221 25879655 10608806 17384638 23346553 12773400 12183412 17525332 15459660 11278964 17296725 11877377 17102137 10550055 16522651
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
DCLRE1A UBE2G2 â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
DCLRE1A CADPS â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
DCLRE1A SDCBP â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
DCLRE1A MMADHC â—¼   KO_DOWN_REGULATES ✅ - -1.2 1.19 PKG 28854368
TP53BP1 ANXA1 â—¼   KO_UP_REGULATES ✅ + 1.21 1.21 PKG 28854368
DCLRE1A MPP1 â—¼   KO_UP_REGULATES ✅ + 1.22 1.22 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
DCLRE1A TBC1D15 â—¼   KO_DOWN_REGULATES ✅ - -1.57 1.56 PKG 28854368
ATM SLC16A3 â—¼   KO_UP_REGULATES ✅ + 1.73 1.73 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
DCLRE1A GSTT2B â—¼   KO_UP_REGULATES ✅ + 2.26 2.26 PKG 28854368
ERCC6 ANXA1 â—¼   KO_UP_REGULATES ✅ + 3.36 3.36 PKG 28854368
ATM ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -4.02 4.01 PKG 28854368
ATM MT1G â—¼   KO_DOWN_REGULATES ✅ - -5.86 5.85 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368