Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216887 14744935
GSK3B FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20154735
GSK3B NBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24879152
TP53 RECQL4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15674334
ERG28 TFG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBE2D1 GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNB2 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LEG1 ANXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ACTA1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 11027608
CAV1 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17502619 0611416104
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
BCAR1 ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 6174726 18164686
PRKCA ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15590896 10592173
ACTG1 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ACTG1 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ACTG1 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ACTG1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PTPN6 ACTG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12646642
YWHAZ ANXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
EGFR ANXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217387 15581623
ZHX1-C8ORF76 ANXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EVA1B ANXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ANXA1 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EGFR ANXA1 â—¼   COLOCALIZATION 2.0 0.8 intact 5217387 15581623
YWHAZ ANXA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSPB1 ANXA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 ATF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
NR3C1 ATF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17016446
ATF2 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20086235 10037779
UBE2I ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
ATM YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ATM CCAR2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 22465953 22735644
HMGA2 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21339738
ATM HMGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21339738
FN1 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16581250 8649368
BMX TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217965 16186805
BMX EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
PTPN11 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
CAV1 PTPN6 â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
CAV1 MMP14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15466865
DYSF CAV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11532985 19380584
TP53 CCAR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20160719 20074560
YWHAZ CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CD44 ITGA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21257905 1018064108
MMP14 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11381077 21385940
RELA CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114294
CHUK NFKBIA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12799363 23430059
RIPK1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18949366 24323043
TNF CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21887257 19287455
CYLD RIPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19131965 23010170
CYLD IKBKG â—¼   DEUBIQUITINATION ✅ 2.0 0.8 Reactome 12917691 15620648
CYLD RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17981138 19131965
DAB2 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPI1 DAB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11823414
DCTN1 HDAC6 â—¼   COLOCALIZATION 2.0 0.8 intact 5215415 12024216
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
DYSF TRIM72 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11532985 19380584
YWHAZ EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217069 15225635
EGFR YWHAZ â—¼   COLOCALIZATION 2.0 0.8 intact 5217069 15225635
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
UBE2D1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
EGFR PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 1845983
TP53 EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
RIPK1 FLOT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
NR3C1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16303956 3611064
HMGA2 FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9690519 9311991
YWHAZ GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PRKCA HDAC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8307255 21952047
SRC HGF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17574028 20802513
HGF PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10871282 10648629
TP53 HGF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
HMGA2 PIAS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11390395
TP53 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPB1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 TDG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14651848 16906147
RPLP0 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS14 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RIPK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10880512 5212735
YWHAZ IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SQSTM1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16874300
PTPN11 JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 8766559
KMT2B TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
TP53 KRT8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8615594
TP53 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
UBE2I MDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RELA MMP14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19303700 21627988
NBN UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SOD1 NBR1 â—¼   COLOCALIZATION 2.0 0.8 intact 8141566 21252941
TP53 NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10698490 12700242
NHEJ1 XRCC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TDG NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129768
OTUB1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PABPN1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PRKCA PIAS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAC1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9148763 10592173
PIK3CA RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9148763 10592173
PRKCA PLA2G4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16963226
YWHAZ PPIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
RAC1 PRKCA â—¼   COLOCALIZATION 2.0 0.8 intact 5218533 16628218
PRKCA YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11950841 16713569
TP53 PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10614633 9895308
PTPN11 SRC â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
PTPN6 TFG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217351 15557341
SPI1 PTPN6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15870198 17218319
UBE2I RELA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25218447 22649547
RELA TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8910340 8524315
YWHAZ RPLP0 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
XRCC6 RPS6KA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SQSTM1 SOD1 â—¼   COLOCALIZATION 2.0 0.8 intact 8141566 21252941
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
UBE2I TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
YWHAZ TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
UNC119 TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UNC119 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YWHAZ WTAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
XRCC6 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MGMT ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
DDX17 DHX15 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
CAV2 EGFR â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
PWWP3A U2AF2 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
ACTA1 ACTB â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
DCLRE1A ANXA1 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
PWWP3A ANXA1 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
ITGA4 YWHAZ â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
UBE2D1 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8379996 22124327
RAD18 CAV1 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
CFTR YWHAZ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
OTUB1 UBE2D1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
RAD18 TP53BP1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
DD19B ANXA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
DD19B LEG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
GBB2 ANXA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LEG1 RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
CD44 LEG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VCAM1 K2C8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CYLD K2C8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27591049 34079125
RUSD3 ANXA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EGFR ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
AGR2 PPIA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
AGR2 ANXA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
AGR2 ANXA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
FRMD1 ANXA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VCAM1 ANXA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ANXA1 XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21900206 30585729
VCAM1 ANXA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
APBB1 SETX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ATF2 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BMI1 RBM14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
CFTR CAV1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CAV3 CAV1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD44 PARP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CFTR DAB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20351096 17110338
CFTR DCTN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
VCAM1 DDX17 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
U2AF2 DDX17 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22365833 26641092
VCAM1 DHX15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
EGFR PTRF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18776048 23956138
VCAM1 HSPB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
XRCC6 PARP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VCAM1 PPIA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RAD18 PTRF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 27377895
PTRF ZBTB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VCAM1 RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 RBM14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 RBMX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
U2AF2 XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26641092 30585729
VCAM1 XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RECQL5 CAV1 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
DDB2 FLOT2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
ATM MDC1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 12607003
RAD18 MMP14 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
TDG RIPK1 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
KI2S2 ANXA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VCAM1 LEG1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 22623428 19738201
ANXA1 K2C8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 9459484
ACTB CAV1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17502619 28734243
EGFR ANXA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25136068 26320552
ATF2 FOSL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 23661758
CAV1 BMX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11751885 16189514
CAV3 PTRF â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19726876
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
CFTR UBE3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19233847 17110338
CTBP1 RBM14 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 30217970 31041561
RIPK1 CYLD â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33654169 22848449 28900035 17981138 21408173
EGFR EPHA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15657067 24797263
ARAF YWHAZ â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CAV1 CAV2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
ATM NBN â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 10802669
DDX17 RBM14 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
NR3C1 RELA â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SRC BMX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 10688651
EGFR CD44 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23265944 12093135 16565089 15597342 11606076
CFTR FLOT2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29924966 17110338
CYLD RIPK1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HMGA2 XRCC6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 18850631
NFKBIA IKBKG â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 8209688 16126728 506093200
IKBKG NFKBIA â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 8209688 16126728 506093200
TNF RIPK1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 23815148 8432069
ATM ANXA2 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
EGFR GAPDH â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
HSPB1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CFTR HSPB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29924966 23155000 26618866 17110338 26627832
DAB2 FGR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12473651 16713569
TP53 UBE2D1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CHUK RELA â—¼   PHOSPHORYLATION ✅ + 0.85 0.85 Signor 10521409
DDB2 RPS14 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
STK4 ANXA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23386615 24366813
ISG15 PPM1B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16884686 16872604
NHEJ1 TDG â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
GSK3B TP53 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
RAD18 DDX17 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
IKBKG RELA â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 15489227
ANXA1 RIPK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 29021293 21383699
COPS6 DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HDAC6 CYLD â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20593489 19893491
XPA ERCC6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20541997 8999876
GABARAPL1 SQSTM1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CAV1 RAC1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EGFR YWHAZ â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HDAC6 SQSTM1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MDC1 ITGA3 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
CHUK RELA â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
GSK3B NBR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29568061 24879152
YWHAZ ARAF â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8009399 19933840
EGFR HSPB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23397142 15657067 24189400
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CYLD IKBKG â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CAV1 PTRF â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
S10AB ANXA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8557678 12645011 16189514 17932043
ANXA1 EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24189400 31980649 15581623 20029029
MDC1 ATM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29656893 26734725 12607005 14519663 18006705 28943310
SRC CAV1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8632005 8910575 8621645 29720121
CAV1 FLOT2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10212252 16189514 34079125
CD44 SRC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21701559 11084024 9519902
DAB2 SRC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12473651 16713569 16189514
EGFR FGR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
STK4 MAP1S â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23455922 24255178 24366813
IKBKG TNF â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
METTL3 WTAP â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CAV1 CAV2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PARP2 ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
GSK3B UBE2D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B ERG28 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B GNB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCH GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19836308
PRKCA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19836308
ERG28 ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CZIB ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
XRCC6 ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KMT2B ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
COPS6 ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FAF1 ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CCT7 ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GAPDH ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DYSF ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
APBB1 ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA1 ANXA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
ANXA1 CAV3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
ANXA1 LRIF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA1 ANXA6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
ANXA1 KLHL23 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA1 OTUB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA1 TRIM72 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
ANXA1 UBE2D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA1 UNC119 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCG ANXA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24103589
PRKCH ANXA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24103589
DYSF ANXA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
ANXA2 ANXA6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
ANXA2 TRIM72 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
ANXA2 CAV3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
DYSF ANXA6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
ANXA6 TRIM72 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
ANXA6 CAV3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
ATM METTL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 32615088 17525332
EGFR BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17145710 17570479 15951569
CAV2 CAV1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9361015 31980649 18081315 12414992 24013648 10212252 16189514
EGFR CAV1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19446582 15657067 24658140 31980649 22411794 34079125 16407214 12354760 25402006 10781609 9374534 12388423 16799092 15273741
EGFR CAV2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 25402006 16799092 15273741
PRKCB CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12070292
RELA COL1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10541434 11277268
UBE2I CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20176810 20098713 12679040
UBE2I DDX17 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22713328 19995069 25114211
RELA EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15964798 21912613 23383347
RELA EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17881446 23379415
FN1 SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FN1 ITGA4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 20644254 22067905 24202395
FN1 ITGA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9733622
FOSL1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19687301 20386569 11028561
HGF PTPN11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17881575 10871282 11323411
SPI1 HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22472882 9315634 9223667
TP53 HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17216187 18431400 9023107
IKBKG RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15489227
NR3C1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18174358 24500711 27371733
SPI1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16263717
NR3C1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15956716 15289446 16557033
NR3C1 PLA2G4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17901074
NR3C1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12734399 9261164 9442377
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
TP53 PIAS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24584189 11877452
PTPN11 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10386953 7522233
RELA PLAUR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12244126 19020743
SHPRH RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
TP53BP2 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 21513714 8152471
UBE3A YWHAZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UBE2D1 UBE3A â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
NBR1 SQSTM1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
DDB2 SQSTM1 â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
BCAR1 SRC â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
ATM NBN â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
MDC1 NBN â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
TP53 UBE3A â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
IKBKG RIPK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
RAC1 CAV1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 24625804 31871319 27250250 15976327 22614015 20460433
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
MDC1 EPHA2 â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
RECQL4 ITGA3 â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
PWWP3A FN1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
SRC BCAR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10085298 21034468 10487518 11514617 10542110 15020686 16849545 12397603 12615911 17038317 10739664 12972425 17129785
EGFR EGF â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 25453753 30083275 21822280 12620237 19531499 25080504 12093292 22729867 23597562 18427122 26280537 18271526 10970856 15620700 11684674 21439278 8663535 28988771 2790960 10788520 10085134 16274239 25241761 17697999 9135143 12297050
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
NBN MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20224574 7891431
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
ATM ALDH1A3 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
NBN ANXA1 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
TP53 TP53BP2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RAD18 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
GSK3B YWHAZ â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
EGF EGFR â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
TP53 TP53BP1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
DDB2 ANXA2 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
XPA ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
CHUK NFKBIA â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
IKBKG NFKBIA â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPLP0 RPS14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CHUK IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFKBIA RELA â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GSK3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23840442 12064478 11709713 9372954 11483158 16552184 17570479 14744935 16713569 21929745 12048243 21900206
GSK3B RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 18201972 15465828 15280197 22761446 20537194 21194439 19345186 21660967 19997086 16407239 25629551 17183360
GSK3B NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 30250038 18838540
TP53 MGMT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17564708 19846904 19056673 9780001 18555750 8616846 21957016 17234766 12503076 20525765 19531487
RAC1 ACTG1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 18391171 16262445 11231582 9600938 15040784 12743368
TRPM7 ANXA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 20932259 20180991 20068231 24465463 24103589 26218331 15485879 21280599
EGFR ANXA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 15581623 31980649 3020049 24782913 2457390 24189400 9223619 17081983 20029029 16052208 22792315 24103589
PRKCA ANXA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 2457390 27634935 19428336 19625660 32133417 24103589 11482905 88309771 15212693
SRC ANXA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24103589 17570479 2457390
PRKCB ANXA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24103589 17570479
ANXA1 FPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 22610094 16278303 10882119 21042851 23230437 12560218 15187149 12368905
ANXA1 FPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10882119 23230437 12560218 15187149 16189514
ANXA1 FPR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15187149
SRC ANXA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 30081903 15302870 24239898 23594883 18083107 2415974 26716413 17389395 27821486 11106497 88296872 16189514 25574848 25303710 2456953 24727000 17287340 2143014 15212693
YWHAZ ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19933840 20936779 25852190 20052757
SRC ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9020159
ATF2 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21479385 8335091 10471826 8703044 9151819
ATF2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 20068037 15356147 11490006 10748079 12509451 10688670 10318823 10913190 10954918 16888805 15546613 20018859 9826775 8816436 8552071
PRKCA ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1661585 9436983 19176525 92095966
ATM ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 24357804 25545367 15916964 28212892 25689427
XRCC6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
ATM MDC1 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM MDC1 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM PARP2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM MDC1 â—¼   ENZYMATIC_REACTION ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM MDC1 â—¼   REGULATES ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM HMGA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17570479 20123066 17525332 21339738 18783938
ATM NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 12433983 12861053 17485521 23146902 10839545 19413330 15302935 27602502 17429352 19523210 24360018 20068231 17507690 17570479 10608806 12598907 18669648 25088203 18003706 11252893 17431132 23097684 10766245 12814430 10802669 21664921 26512707 10839544 11927276 21130714 17525332 12447395 14707289 15733840 15279770 25119968 18644472 28822740
ATM DCLRE1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15456891 18848520
ATM MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 28193847 21705321 22234877 12607003 12607005 22234878 17525332 18006705
ATM IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 27486774 21490922 20932476 20188669 18583959 22435563 28626800 24957606 16497931 21872579 20932475 19917246 16965765 23063077
ATM CCAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26158765 23357756 26194823 27503537 22735644 24567900 17525332
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
SRC BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 19901323 24962474 11514617 8670206 15316024 20927395 8070403 17389395 12480533 22710723 30422386 25976166 17570479 21963850 12972425 20103658 17129785 10487518 15817476 21301050 10739664 17038317 21765460 17016520 12397603 15212693 15020686 10542110 23457577 10085298 12615911 15272013 21034468 11604500
SRC BMX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 27601470 17570479 16189514 10688651
CAV1 SRC â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
TP53 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10684646 20610713 17014845 11076533
SRC CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 20201820 23469926 24755228 24525631 15592455 27259249 17979878 19409422 11075810 17389395 14992595 18578522 11094059 11451957 24244013 8632005 24131997 12921535 21324536 16332692 8621645 18815812 27170175 17517963 12531427 24632723 23091071 19625610 18789131 24502576 17016520 20107068 21382479 24364863 25937636 19604397 23280667 16713182 22596063 26169283 8910575 17190831 18707149 25097454 12036959 18176934 15212693 18400052
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
SRC CAV2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 23826261 15212693 15504032 20455999 17081983 12091389 20068231 22819829 18081315 18669648
FN1 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1730778
COL1A1 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1730778 16189514
PRKCA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 92316961 15212693 26888287 1377674
IKBKG CHUK â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
CHUK RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
TP53 CHUK â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15469934 11557753 17434128
IKBKG CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17145710 17485448 16938294 11865184 11877453 16970925 22435554 17244613 17568778 17363905 16818229 15084594 15485931 24369075 20300203 21217011 12799363 23180781 14743216 16319058 21703539 19666608 20098747 12612076 16126728 15218526 23430059 9751060 20138012 18716620 20368414 10837071 25355947 15836773 23109003 20531300 17702576 17363973 15214841 12459277 17561400 21640763 16285893 28462531 12709429 10968790 15199157 26192618 12133805 16497931 11864612 17693255 17072322 11340079
SRC CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 12707358
PEBP1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11585904
CHUK NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 113.0 1.0 Omnipath 17145710 15922746 11087742 18074035 12626540 11527961 9244310 11809792 15836773 16177806 9721103 18501560 11923072 17706453 9509763 10723801 11858955 10421793 25133483 10398585 9346484 9346241 21765415 8657102 16737960 9315679 9252186 21490922 16219905 14743216 20484017 10329646 18922877 10882136 16153868 10195894 14751757 16007147 7796813 17053167 9632633 15856023 17965022 10783893 10602462 23602409 27682876 10469655 16965765 15084594 16493072 11095741 12138192 10723127 15210742 10329681 7878466 26930276 9914500 9520446 12514169 12403772 10527519 15145317 16493424 9135156 16023083 12637324 10593898 14636585 9214631 7862124 10074115 15389589 12486103 9891086 8601309 10880512 7739562 16286467 17379600 23109003 9689078 15371334 10733566 29145629 11042193 23970940 10085062 17468758
CHUK RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17145710 15611276 22110409 19609947 10521409 20863851 20051109 20363318 12767944 26999213 12842894 21903422 19110719 15858576 16382138 22155370 23894194 16046471 15128824 21569639 16846590 8246997 15485852 25341660 15494311 11983155 15980040 15489227 15849198 14636585 23343355
CHUK CYLD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19481526 24614225
CYLD IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 21988832 15341735 15870263 22990857 12917689 12917691 16627981 20932475 26802121 12917690
PRKCG DAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10542228 11812785
XPA DDB2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
EGF EGFR â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 15003992 15175028 15466195 15958574 18423981 19631971 20430953 21098712 8101258
EGF SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23349873 19481075 15845350 22927910 27462789
EGF EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 131.0 1.0 Omnipath 17145710 17081983 21822280 20813200 23613900 9135143 25453753 21303971 10209155 26821125 12297050 27387652 25241761 30083275 12093292 30197274 21649524 19531499 18762250 16729043 26921391 17697999 17575160 21722395 12620237 19129184 10788520 23331499 3494473 15620700 14568001 15958209 24096486 18253097 16843263 18320059 21532939 10085134 22260327 15708576 26280537 23912460 21858221 11116185 10970856 27462018 18427122 25080504 20953304 19135477 11684674 8639530 27564112 18270696 2790960 17971399 23185569 19895983 28988771 29617357 23597562 19531623 23950932 21071413 8663535 6289330 16274239 17563729 21439278 20458382 22216880 18271526 12771140 21311755 24709886 25366117 12648462 21107857
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
PRKCB EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 7805884 17570479 12040186 19568798 15567848 14585353
PRKCA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 11447289 8321321 11313945 25402006 12040186 20888375 15302935 6321473 1860884 12878187 6090944 19568798 14585353 17496910 21386996 24658140 2984676 11940581 31980649 15212693 85012702 19615955 2987962 12845332 3379075 7805884 10816576 15567848 16488589
PRKCG EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
FGR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 31980649 24658140 11160627 25402006
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
RIPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11116146
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
PTPN6 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 9038217 9287352 7673163 7518460 9733788
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
TP53 EPHA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11641774 21394211 17050670 23518503
PRKCA EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 32413552 12040186 19568798 15567848 14585353
SRC EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24457997 28957431 26788993
ERCC6 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16713569 10882116 19221478 18784753
RIPK1 FAF1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
RIPK1 FAF1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
SQSTM1 FAF1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 12702723 15340068 16252010 16498403 20531300 21981924 23069999 25002027 26587781 28574505 9184224
RELA FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10649441 18064631 10867646 22223884 12372417
HGF FN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8780385 25241761 15717924
FN1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9117345 9842903 19738201 11010812
FOSL1 PLAUR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11234878 16893520 8798512 10471035 17510314
NBR1 GABARAPL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20562859 21620860 19250911 23022382
GABARAPL1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17580304 20562859 23022382 21691068 25416956 31053714 16189514 32296183 21617041 19250911
HLA-B PTPN11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
HLA-B PTPN6 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
HMGA1 HMGA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
HSPB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25241761 16169070 16713569 17184779
HSPB1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 12897149 9047237 16439988 19324872 18266962 14761954 9169414 10694513 19011223
TP53 IFI16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15728246 11146555 12925527 18974396
IFI16 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11146555 21397192 16713569
TNF IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
RELA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
RIPK1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
NFKBIA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
IKBKG NFKBIA â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG RELA â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
TNF IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
IKBKG IL6 â—¼   DOWN_REGULATES ✅ - 38.0 1.0 ACSN 10542212 10754326 10952726 11875494 12133805 12907458 14660645 15199157 15465827 15485931 15536066 15644117 15749903 16243976 16413922 16818229 16878026 16970925 17237376 17254973 17363905 17404308 17485448 17693255 18716620 20138012 20300203 21217011 21807870 22435554 23086447 23390297 23422957 23430059 2649237 28462531 7594497 9743347
RIPK1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10880512 21383699 21458669 14653779 10980203 17702576 9927690 16603398 16547522 16965765 10755617
IKBKG NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 17145710 7862124 11087742 10602462 16818647 8657102 16965765 22435544 11064457 24369075 10880512 7739562 14743216 16319058 7878466 16126728 10329646 15836773 16177806 21217772 16153868 10195894 12514169 18617513 15371334 16493424 17706453 15145317 10723801 15870263 7796813 17468758 16603398 17965022 11830587
PTPN11 IL1B â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 1238444 12393695 12421919 12707331 15169881 15240681 15699106 15713798 16204085 17307799 19406987 19479342 19833085 20363967 20435894 21469115 22483603 22683124 22955274 27557510 9751747
SPI1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10801783 11359842 7799967 18173740 18566416 9376596 11823535 19423615 10328874 17283046 10453013 16439360 17386941 7609733 12061786 9360994 10490619
RELA IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 26596471 27338466 11114294 8413223 20975042 17707233 23383347 11058167 12686724 16433741 23667107 15382119 19122653 24009751 27211851 18566416 15292915 20617571 23056550 12517972 18285351 19843519 22267743 15812237 25161822 22388040 8021507 9878621 14960579 10963848 23195252 11395507 27534992 9058643 15543947 19846753 20696864 8679226 24908318 28389361 27371733 15972680 20336759 10080875 17082635
IL1B RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25606026 26999213 22240205 23666959 19197368 25306394 24009751
PTPN11 IL6 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 1238444 12393695 12421919 12707331 15169881 15240681 15699106 15713798 16204085 17307799 19406987 19479342 19833085 20363967 20435894 21469115 22483603 22683124 22955274 27557510 9751747
IL6 TNF â—¼   DOWN_REGULATES ✅ - 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
RELA IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 114.0 1.0 Omnipath 26596471 19124729 10373597 9523851 23595969 28270510 21537341 17982049 15226358 18243142 12200447 20371366 24664372 23874122 14532843 18942706 10975857 21278793 10469356 22547075 17490702 11459775 23335080 10569191 19707556 19687301 7499267 8290595 23857586 24676671 18061164 11058167 12887736 15013753 15158360 22661093 20935672 20511231 17350185 10903137 16112536 27413250 21810609 16984731 16166627 18469854 12881425 24012417 23386688 22105366 8752656 12176740 27371733 22578249 18057724 20351184 10329846 19164127 10542237 11564778 20221401 15517885 19122653 20534538 7876168 27211851 9516466 18996370 8824277 18310089 21104991 25888873 12359431 11327783 20066113 20100571 19703987 19469019 21106671 16960103 18502099 16043358 21996739 20650996 22021035 11120852 12672795 12058956 18483242 22189669 14976218 17495236 11007957 21131967 11975924 27337441 9182853 10963848 17040605 11504280 15756023 10823821 17932106 19966855 20696864 12177065 8679226 9199307 17196927 20457835 21098092 17532054
NR3C1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19436110 8175711 27371733 11459775 8290595 21474440 2233715 1871124
SPI1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15013752 23509362 18680724 19502584 25567680
ITGA3 SRC â—¼   ENZYMATIC_REACTION ✅ 56.0 1.0 ACSN 10671552 11133108 11348595 11476890 11955436 11967263 12051714 12426320 14557817 15001769 15279786 15548370 16039586 16099633 16371504 16474430 16919435 17143292 17303408 17496910 17517963 17660363 17928543 17934056 17936032 18037882 18590585 19010789 19029934 19109155 19171760 19619488 19734908 19920116 20519943 20644162 20705860 21278795 21666923 21900405 22007144 22174153 22203675 22370635 22674073 22703233 23343194 24023259 25572304 25730849 26552706 27216177 7542250 7575488 7594497 8666229
VCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22623428 19738201 11751331
THBS2 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14699013
PTPN6 JAK3 â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 18097461 15317731 16825495 19459784 16871283
PTPN6 JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9520455 18988627 11021818
XRCC6 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
MDC1 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 15201865 20460517 23115235 14519663 18001824 18678890 19804756 18583988 19230643 12607003 12607005 20224574
NBN XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
NBR1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20562859 29343546 16861740 20808283 15802564 24879152 25007327 19250911 12813044 21935636
NR3C1 NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11694573 12361720 7569975 15879558
RELA NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18204072 17876798 24083678 15499023 25759022 23422506 12859951 7775482 11744993 22723832 23450368 11060311 12885753 18981184 9250151
SRC NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 24216290 12432072 24637265 12429743 25671697 14991073 8797825 24101387 9792645
RELA NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 134.0 1.0 Omnipath 17145710 15657065 11801607 25609694 15226358 17003112 9057089 26496610 19219072 23850221 7831327 12927781 16683270 17301240 17561400 9566883 10391945 8887633 16209943 21719482 10066434 8657102 10581242 29734393 21988832 12419806 14743216 16105840 15671248 9751059 9990853 25759022 10498867 8246997 7878004 11020244 9426183 15845455 26476452 23563313 16951195 25520503 9694722 11287411 10329681 15799966 17612295 24457201 10085161 10837071 10969074 11571291 9573251 15214841 16846590 20065107 7479976 24248593 8887627 15145317 16493424 9135156 24634218 7479848 15024091 14636585 26463447 7862124 1340770 22081069 8139561 27923823 16970925 9738011 9865693 9572494 11231305 14685242 20797629 11313474 16226509 14690596 22022389 21217772 26186194 30213788 15371334 8978697 20980497 7739549 7628694
TNF NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19053972 24083678 25215581 29088783 24386331 25888769 20460401 16866128 19934328 9363938 24349153
XRCC6 NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
RELA NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
NR3C1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
PRKCG PEBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20068231 20166139 12551925 14654844
PRKCA PEBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17170028 20166139 20068231 12551925 14654844 19096942
SRC PIK3CA â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 12682286 15314172 20861220 18657504 11689445 12431978 25587652 11044445 22266855 11029403 11029009
SRC PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12750372 10592173 17275257 10830300
PRKCA RAC1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10679481 10871288 16492141 18851840 20027184 21474067
PRKCA PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15269224 11781100 25876760
PRKCA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18812399 9935181 15659650 9315650 19933256 16713569 9571186 1454855
PRKCA PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16055440 11781100
PRKCA RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16628218 20027184 11284700 18851840 21474067
PRKCA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 17496910 11940581 21386996 10527887 2996780 11447289 19615955 16488589 6321473 8321321 12845332 11313945 2136766 17570479 12040186 19568798 15567848 14585353
PRKCB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCG SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCH SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 8621384 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PTPN11 PTPN6 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283
PTPN11 PTPN6 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283
PTPN11 TNF â—¼   DOWN_REGULATES ✅ - 26.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 1238444 12393695 12421919 12707331 15169881 15240681 15699106 15713798 16204085 17307799 19406987 19479342 19833085 20363967 20435894 21469115 22483603 22683124 22955274 27557510 9751747
PTPN11 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18757826 18482983 10698938 17974954 14687660 24632723 20308328
SRC PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 8692915 17675340 14551136 25535246 14699166 12468540 10574931 16649996 8647855 7512963 9261115 34010642 14757045 12468645 8114715 15212693 10488096 21900501
SRC RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22163037 17991704 21798346 26816343 29036929
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
RELA VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10833420 20966071 16317091 7536741 16627481 16385502 10946302 19422386 22708120 23042817 19281832 10553096 10329958 11359843 7692229 16249517 10496926 7537851 16453001
RELA TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 136.0 1.0 Omnipath 26596471 17707233 20817730 12686724 27075886 21765477 21537341 19530226 17390058 18077329 15064230 20617556 8805669 17351769 23335080 21573233 17292554 16285952 9916895 11749970 7895918 17496784 12628924 23857586 12657243 15857826 12471036 11259437 16433741 9831247 20237317 15465827 26023919 22661093 10748079 15013838 17350185 10754326 15470505 11827962 20139176 26408955 22901690 18772140 21108432 22742857 23195252 18362169 24012417 11312646 17442180 9281604 10079106 11297551 15081318 22718766 24908318 8219230 26004152 11094063 11490006 9916692 16483936 18057724 16569682 22138107 18467438 20547752 22723832 19846753 17407192 20221401 19854828 20534538 7876168 16707469 12117498 20544543 23178569 15812247 21138578 12610112 25888873 16916598 16040075 28039105 14749357 20066113 19285436 25161822 22388040 14960579 20195282 16199883 15543947 23971673 10551799 11290773 22798670 22021035 20722069 20221720 27338466 19385047 12058956 26997758 25690886 7624137 20686703 26114754 14976218 10485496 17607667 8622636 11007957 18285351 10837498 11739517 18719026 17268554 17085785 17142966 10963848 9742085 23042817 27534992 10553096 26516703 20696864 10201927 16850160 8679226 21098092 20097764 9129150 17082635
TNF RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 15192014 27329558 22240205 15833743 19351843 28187781 15841081 28107185 28373828 26999213 24386331 24957606 26179215 21572963 18258304 28317833 29441018 10722927 19596989 28423685 12881425 25118327 24036851 28089769 21904602 24141032 10938077 30201812 20691659 24166907 19789307 19393267 22768286 26310932 19411070 23789107 28790310 29708974 20507904
RPS6KA4 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17183360 12628924 19933278
RELA TP53BP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18448430 16713569 10498867
RIPK1 TNF â—¼   PHYSICAL_INTERACTION 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
RIPK1 TNF â—¼   SHARES_COMPLEX 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
SQSTM1 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 12702723 15340068 16252010 16498403 20531300 21981924 23069999 25002027 26587781 28574505 9184224
SQSTM1 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26416459 10356400 19850933
SPI1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18802049 10748079 19646961 8998076 18408586 18357389 25567680
UBE2I TDG â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15823533 18691969 21284855 15959518 11889051
UBE2I TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18512959 24753249 18691969
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
UBE2D1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
UBE3A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 23040663 7724550 9450543 16713569 16493710 15001357 17131388 9143503 19364824 31971989 11027293 9688277 9369221 1661671 7708685 12620801 8090726 8380895 26789255
TP53BP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25579814 12110597 25837623 16713569 14978302 22653443 26022179 27546791 8016121 12351827 15611139 15364958 14985081 19433796 17805299 25651062 11877378 17634560 22084066 20307547
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
TP53BP2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 14985081 16139958 8875926 25502805 8016121 21513714 31515488 16713569 8668206 18275817 11839776
XRCC6 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
UBE2I UBE3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15340381 12820959 18997815 15668399 18298802
MDC1 BCAR1 â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
MDC1 ANXA2 â—¼   KO_UP_REGULATES ✅ + 1.09 1.09 PKG 28854368
DDB2 ZBTB1 â—¼   KO_DOWN_REGULATES ✅ - -1.11 1.1 PKG 28854368
MGMT DAB2 â—¼   KO_UP_REGULATES ✅ + 1.15 1.15 PKG 28854368
MDC1 ALDH1A3 â—¼   KO_UP_REGULATES ✅ + 1.18 1.18 PKG 28854368
SHPRH ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
TP53BP1 ANXA1 â—¼   KO_UP_REGULATES ✅ + 1.21 1.21 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
TREX1 CAV1 â—¼   KO_UP_REGULATES ✅ + 1.24 1.24 PKG 28854368
MUS81 CAV1 â—¼   KO_UP_REGULATES ✅ + 1.25 1.25 PKG 28854368
SETX CAV1 â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
TP53 ALDH1A3 â—¼   KO_DOWN_REGULATES ✅ - -1.28 1.27 PKG 28854368
TP53BP1 CAV1 â—¼   KO_UP_REGULATES ✅ + 1.29 1.29 PKG 28854368
RAD18 ERG28 â—¼   KO_DOWN_REGULATES ✅ - -1.32 1.31 PKG 28854368
ERCC6 CAV1 â—¼   KO_UP_REGULATES ✅ + 1.33 1.33 PKG 28854368
SHPRH FN1 â—¼   KO_UP_REGULATES ✅ + 1.34 1.34 PKG 28854368
TDG CAV1 â—¼   KO_UP_REGULATES ✅ + 1.37 1.37 PKG 28854368
MUS81 ANXA1 â—¼   KO_UP_REGULATES ✅ + 1.4 1.4 PKG 28854368
GEN1 ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -1.42 1.41 PKG 28854368
SHPRH CAV1 â—¼   KO_DOWN_REGULATES ✅ - -1.43 1.42 PKG 28854368
RECQL4 CAV1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368
RECQL5 ANXA1 â—¼   KO_UP_REGULATES ✅ + 1.6 1.6 PKG 28854368
TDP2 CAV1 â—¼   KO_DOWN_REGULATES ✅ - -1.7 1.69 PKG 28854368
RECQL4 FN1 â—¼   KO_UP_REGULATES ✅ + 1.74 1.74 PKG 28854368
SETX ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -1.87 1.86 PKG 28854368
RECQL4 ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -1.92 1.91 PKG 28854368
ATM CAV1 â—¼   KO_DOWN_REGULATES ✅ - -1.92 1.91 PKG 28854368
TDP2 TDP2 â—¼   KO_DOWN_REGULATES ✅ - -2.0 1.99 PKG 28854368
TDG ANXA1 â—¼   KO_UP_REGULATES ✅ + 2.01 2.01 PKG 28854368
MDC1 CAV1 â—¼   KO_UP_REGULATES ✅ + 2.03 2.03 PKG 28854368
DDB2 CAV1 â—¼   KO_DOWN_REGULATES ✅ - -2.05 2.04 PKG 28854368
TREX1 ANXA1 â—¼   KO_UP_REGULATES ✅ + 2.09 2.09 PKG 28854368
NHEJ1 ANXA1 â—¼   KO_UP_REGULATES ✅ + 2.18 2.18 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
TP53 FN1 â—¼   KO_UP_REGULATES ✅ + 2.36 2.36 PKG 28854368
DDB2 ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -2.39 2.38 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
TDP2 ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -2.81 2.8 PKG 28854368
RAD18 ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -3.21 3.2 PKG 28854368
ERCC6 ANXA1 â—¼   KO_UP_REGULATES ✅ + 3.36 3.36 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
TP53 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -3.51 3.5 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
MDC1 ANXA1 â—¼   KO_UP_REGULATES ✅ + 3.97 3.97 PKG 28854368
SHPRH SHPRH â—¼   KO_DOWN_REGULATES ✅ - -4.0 3.99 PKG 28854368
ATM ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -4.02 4.01 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
MGMT MGMT â—¼   KO_DOWN_REGULATES ✅ - -4.42 4.41 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
NBN NBN â—¼   KO_DOWN_REGULATES ✅ - -6.31 6.3 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368
RECQL5 RECQL5 â—¼   KO_DOWN_REGULATES ✅ - -7.08 7.07 PKG 28854368
SETX SETX â—¼   KO_DOWN_REGULATES ✅ - -8.56 8.55 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368