Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
KRT8 ZNF804B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VIM MEIKIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT18 MEIKIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 MEIKIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 ADAM12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PLEC AHCTF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 AHCTF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VIM AHCTF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT18 AHCTF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 AP3B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KAT7 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212855 10930412
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
AR KRT8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16046619
AR RCHY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16914734
AR CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24218937 20610535
AR MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14619959 20610535
AR HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 21125667
AR KRT18 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17721441
KRT8 ARFGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 ATF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
KMT2A BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056311 19208841
KRT8 C2ORF78 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
PTPN1 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
KRT8 CCDC71 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 CCDC96 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT18 CD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 CD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MAPK1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17205132
KRT8 CUX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 DCDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GRB2 ELK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAPK3 ELK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11042694
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
ESR1 MAPK12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16885352 22399296
ESR1 PRKCD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22430216 18414489
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
ESR1 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6673088 7539106
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
ESR1 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14605097
ETS2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8649821 10510472
ETS2 KRT8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8892757 7510396
KRT8 F11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SEL1L FAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18711132 0805371105
VCP FAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18711132 0805371105
VCP FAF2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
FAF2 VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
KRT8 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FGFR3 KRT33B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 KRT19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 MAPK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KRT8 GDPD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 GPR37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PPP2CB GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB2 ITPR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PLEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 KRT17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 UACA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB2 KRT18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
HSPA5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KAT7 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21221131 15899857
VIM IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KRT18 IRAK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 IRAK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TRAF6 IRAK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10383454 5211610
KRT8 ITPR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YBX1 KPNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20596676
KRT18 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TCHP KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRT19 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRT18 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT18 PLEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT18 PEX5L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAF1 KRT18 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15314064 5217163
RAF1 KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15314064 5217163
NES KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NEUROD2 KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VIM KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PLEC KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYH1 KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TJP1 KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219015 16944923
KRT8 ZNF704 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 LSG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 OVCH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 TTC33 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 ZNF484 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 TTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 PRR22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 LRP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 TRAPPC11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 LCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 ZNF708 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 MTRF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 PEX5L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 NAA10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 UACA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 NLN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 KRT8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8615594
KRT8 PASK â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 21418524 8145255
KRT8 PPL â—¼   COLOCALIZATION 2.0 0.8 intact 8388011 22841549
TP53 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
RAF1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
PRKCE MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11350735
MAPK1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15778365
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
RAF1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
PRKCE MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16810323 16461926
VIM PEX5L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TJP1 PLEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219015 16944923
PRKCE TJP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23967087 24727247
PRKCE RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11350735
YWHAQ RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
RCHY1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 5220017 17568776
SYVN1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 17170702 5219455
TCHP VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
YBX1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12835324 16963428
TP53 YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18504427 22417301
VCP TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VIM UACA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT24 TCHP â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
SYVN1 GPR37 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 18344614 17059562 15572843
SEL1L VCP â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
KRT25 PPL â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
VCAM1 ANXA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
LRRK2 AP3B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24725412 27424887
ESR1 APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
BMI1 PLEC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
CFTR CAV1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
VCAM1 CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ESR1 OTUD4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
VCAM1 GRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
LRRK2 PLEC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20876399 31046837
VCAM1 PLEC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
TP53 YBX1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
FAF2 CAV1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AR RCHY1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
SOX2 CDK1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23667531 30297536
ATF2 MAPK11 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
MAPK1 RAF1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CFTR FAF2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
FGFR3 GRB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9045692 26344197
DERL2 SERPINA1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
KRT16 TCHP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
MAPK1 MAPK14 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MAPK1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
KRT27 PNN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
MAPK14 TP53 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
KRT18 KRT8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
KRT19 TCHP â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
DERL2 FAF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MAPK8 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
BYSL KRT40 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT35 TCHP â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
RCHY1 TP53 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
GRB2 LCP2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
KRT34 TCHP â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
TP53 RCHY1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 17568776 5220017
TP53 RCHY1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 17568776 5220017
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
BYSL VIM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
TP53 APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18208837
AR TJP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18535113 20610535
AR PRKCD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17553165 17178875
AR CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18794357 20610535
AR PTPN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22282656 20610535
ATF2 PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8647095 11179965
CAV1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23634843 11563984 22230296 19595769
ESR1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12138116 18414489
TP53 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15383401 20332115 21478913
PRKCD CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 27203386
ETS2 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7867724 12760745
VCP DERL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21357747 23867461 19002207
SYVN1 DERL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21357747 23867461 19002207
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
PPP2CA IKBKG â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 506986200 8205130 16129692
VIM KAT7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
QRSL1 KRT8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PTP4A3 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19115206
MAPK13 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11788583
MAPK12 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11788583
MAPK11 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11788583
PPP2CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 MAPK14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11437382 15132979 14570892
PPP2CA MAPK3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
PRKCD MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17183360 16483929
RAF1 PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 502464200 8203796 16239230
RAF1 PPP2CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 502464200 8203796 16239230
PPP2CB PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11959144
PTPN1 PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17570831 15133032 11350745
VCP SEL1L â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21357747 23867461 19002207
TP53 SYVN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
RAF1 YWHAQ â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
LRRK2 YWHAQ â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
BYSL ZRANB1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
ATF2 MAPK8 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
ATF2 MAPK14 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
DERL2 SYVN1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
IKBKG TRAF6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
DERL2 SEL1L â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
IRAK3 TRAF6 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10383454 32296183
DERL2 VCP â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
LCP2 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10224278 8695800 32296183 19380743 9565634 11314042 7706237 20936779 12176364 10204582 8995445 25416956 9716598 15929943 17235283
FAF2 VCP â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SEL1L SYVN1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
SYVN1 VCP â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
APEX1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18786561 19180539 9119221 19737086 16713569
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12020745 20610535 14684616 18451309
RCHY1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12200228 16713569 27903893 17721809 16914734
KAT7 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10930412 16713569
MAPK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18511414 9725910 10318905
MAPK14 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 30644418 24424504 21820033 16282370
CASP1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9535906 16713569
CDK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 26573794 12569365 22275373 25704883 17043241 23321516 9725910 24480624 21799006 24424504 28062857 21820033 25950519 28415597 27450452 25691442 21782001
MAPK8 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24424504 21512132 21820033 16282370
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
ATF2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11274345 12738796 18039929 20506250
ATF2 RAF1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11274345 12738796 18039929 20506250
MAPK8 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 11279118 17081983 20506250 12958075 9162092 19255142 8654373 20028971 15105425 17626013 12788955 11566021 15550563 10777545 23331499 7535770 15068801 21071413 17875713 9317150 16393692 15304344 18988627 7737130 26538579 21444723 602896 11896587 12110590 7824938 11274345 12874243 11971971 9399639 19436832 16533805 9670022 9029150 11865055 9207092 12804775 7737129 15212693 9405416
MAPK14 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 17081983 18767875 21098032 20506250 26359454 19690332 11060298 19413330 12788955 10085140 22037767 11566021 17079470 19647037 10581204 10777545 7535770 23331499 7839144 19324872 21071413 21614932 20068231 16393692 15304344 17570479 17380123 18988627 7737130 18669648 15187187 9305639 7737129 15140942 602896 11896587 17548358 12110590 7824938 8663524 33893075 12024021 11078583 11971971 9707433 17258390 10821277 19651622 19436832 11259586 27726305 11781825 9430721 27142525 10909971 12118074 15569672 15212693 9753474 11274345 10903740 26987986
MAPK1 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10777545 17081983 21098032 9430721 12110590 20068231 19690332 15304344 19413330 10878576 15192015 7737129 18669648 19647037
MAPK3 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10777545 12110590 20068231 15304344 15192015 19647037
PRKCE ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24727247 22304920 24357804 25545367 26645581 25728676
MAPK13 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 9207191 10581204 15140942 20506250 21614932 19135240 16393692 12244047 11274345
MAPK11 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 17145710 17081983 20506250 19690332 19413330 17079470 11566021 10085140 17254968 10777545 7535770 7839144 21614932 16393692 15304344 17380123 7737130 15192015 18669648 15187187 15140942 9235954 12110590 17258390 19436832 9155018 9430721 9029150 14734562 11274345
MAPK12 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 15140942 20506250 9029150 21614932 11238375 16393692 10085140 11274345
TP53 CASP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16135520 12459463 15580302 21943362 11278253
ESR1 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11773442 17535799 15033483 22031296 15496458
TP53 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10684646 20610713 17014845 11076533
PTPN1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 16388599 12176037 16189514
ESR1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12726856 14500345 17893710 19383788 19593637 20101232
PTP4A3 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15169839 17615296 22796940 20818389 21685935 20519943 12508111 24376839 11309385 23691193 19597490 14673164
TP53 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10825186 11593387 12874009 19472317 10514438 11313928 16807237 8270002 17942917 9275177 20395210 11032828 19861536 12889596 19067706
CDK1 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 97207326 17570479 11788583 9054461 9524113
CDK1 PLEC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17570479 19709076 8626512
CDK1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 82.0 1.0 Omnipath 19007248 16565220 17081983 22120848 18767875 9168797 19690332 27603133 15766329 12761892 19413330 21465480 19664995 16260496 19415658 25960391 18578522 20068231 15713670 17570479 24073199 18491316 18669648 18691976 17287340 15345747 20068230 19651622 20058876 19691289 17924679 16542212 19369195 25184044 18707149 7983050 19584300 16964243 21422740 18212344
CDK1 KAT7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18250300 19690332 19413330 23955388 16964243 18669648
CDK1 KRT18 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19415658 19007248 10623656 15368451 16083285 20068231 9524113 18669648
CDK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 24173284 12767922 1584757 20661218 26029996 2141171 9467949 17570479 20808790 7862459 11327730 11078726 27726420 8357826 16713569 2156209
CDK1 CUX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11584018 17570479
MAPK14 ELK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11042694 9130707 17570479
MAPK8 ELK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 11042694
ESR1 KRT19 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11026574 18414489
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
ETS2 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 8552081 10358095 20534573 11782450 15572696
ETS2 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 8552081 10358095 20534573 11782450 15572696
FGFR3 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR3 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
GRB2 RAF1 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
GRB2 RAF1 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
GRB2 ITGA4 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
GRB2 LCP2 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
LCP2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 7706237 20936779 10224278 8695800 17235283 15929943 25416956 19380743 9716598 32296183 10204582 11314042 8995445
MAPK3 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24089523
TRAF6 IKBKG â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18180283 18347055 21220427 16547522
TRAF6 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17562858 17728323 17947236 14695475 18180283 15620648 15125833 12867425 11057907
IRAK3 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21098228 17145710 10383454 32296183
IRAK3 TRAF6 â—¼   DOWN_REGULATES ✅ - 4.0 1.0 ACSN 12150927 12620219 14660645 18264787
VCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22623428 19738201 11751331
PTP4A3 KRT8 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 19115206 23691193 24376839 24686170
MAPK14 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19007248 15212693 18691976 11781324 11788583 9211903 15972820
MAPK8 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19007248 18691976 11781324 17570479 11788583 9211903 15972820
PRKCD KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15972820 11781324 9211903 11788583
TP53 LITAF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10321740 21836606 17283168 15197774
RAF1 MAPK1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
PPP2CB MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18039929 16680151 16456541 10995457 18042541 7780739 18588945 2154696
PPP2CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 10592173 7780739 18588945 2154696 20626350
MAPK13 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK14 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15187187 21675959 18039929 12738796 11157753 22521293 17255949 11238443 11274345 12697810
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 17081983 18767875 15849194 19690332 11409918 14654779 23331499 23180781 8226933 20068231 18988627 21917714 18669648 19541618 18691976 16407412 19933846 9922370 15664191 8388392 19651622 10801873 8349614 18775330 9604935
MAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 14965474 9765199 15116093 21675959 23443559 10781582 25241761 10446957 10958792 11409876 11709713 21147777 10673501 11551930 15867353 11875057 12091386
MAPK11 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15187187 17145710 19436832 15140942 10212189 20506250 21614932 16393692 17254968 11274345
MAPK12 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15187187 19436832 15140942 20506250 21614932 16393692 24818748 11274345
MAPK13 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 15140942 10581258 20506250 21614932 16393692 24818748 11274345
MAPK13 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
TRAF6 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10346818 17965022 15692051 17947236
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 21675959 26247731 20213747 17535811 20506250 15657900 9315650 15642743 19413330 11283254 22975381 10581258 16083285 1088347 21614932 16393692 10884347 21050851 16552184 10747897 15187187 17906639 25789565 15140942 11258706 24818748 19436832 10781582 10212189 17172861 10348343 11078726 11274345
RAF1 MAPK3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
PPP2CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 18588945
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MAPK3 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 14654779 23331499 19541618 18691976 16407412 19933846 9446616 9922370 15664191 18988627
TP53 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22607268 23376463 18374905 15958553 10854211 22353755
TRAF6 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10346818 17965022 15692051 17947236
MAPK8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 11108663 12531896 16713569 11283254 10706102 19651615 27147566 9724739 15538975 9732264 10581258 10436023 17570479 9393873 11896587 12514174 15580310 18813780 11078726
PPP2CA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18039929 7604263 16680151 16239230 10995457 18042541 18588945
PPP2CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17245430 14712210 1848668 16713569 12556559
PPP2CA PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11959144
PPP2CB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1848668 17245430 14712210
PRKCD TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17906639 16314418 16377624
YWHAQ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 14688280 7760835 17353931 16041367 11697890
RAF1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 14688280 7760835 17353931 16041367 11697890
RCHY1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 21988832 19483087 17568776 24367557 25116336 21084285 12654245 21791603 20452352 19043414 16713569 31630802 27519799 19918835
SYVN1 SEL1L â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12847084 16186509 18199748 18360008 19509052
SYVN1 SEL1L â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12847084 16186509 18199748 18360008 19509052