Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CLU APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
F7 F10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29880919 11560488
TFPI F10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 3422166 12787023
F10 F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25769543 35114109
FGG ITGB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10438935 16239428
FGB ITGB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10438935 16239428
FGA ITGB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10438935 16239428
CFB C3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 809512 279011
C3 CD55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6238120 8786315
CFD C3 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 809512 279011
C3 CPB2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 11939578 4098172
APP PLAU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
F2 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10996659 8428004
PLAU PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7721771 16189514
VTN SERPINE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216470 12808446
SERPINE1 PLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11113116 16713569
PLG PLAT â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2318848 7199524
PLG PLAT â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 2496749 2962641
PLG PLAUR â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 3023326 2935528
PLAT PLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11928826 1447176
SERPINB2 PLAUR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 3090045 2166055
PROS1 F8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 7620160
APP F12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP F2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CFB CFH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1067618 301546
VWF GP1BA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215664 12183630
AIRE F11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22883565 22203960
FGA ITGAX â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10543983 17339034
F8 F2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0801735105 18492805
F2 PROC â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 468991 2538457
F2 PROCR â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 468991 2538457
SERPINA5 F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12878585 18362344
FGB ITGAX â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10543983 17339034
F9 F3 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 2040636 2248955
F9 F7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 2040636 2248955
SERPINC1 F9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 31030036 20080729
F7 F9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29880919 2248955
F9 F7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2248955 12524220
VWF F8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0801735105 18492805
A2M KLKB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2579948 6203908
F12 KLKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28966616 3521732
SERPING1 MASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10946292 28742139
MASP2 C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11907111 11527969
MASP2 C4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17204478 22949645
C5 CPB2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 11939578 4098172
C6 C7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17900710 10696521
SERPINA5 PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 2551064 16189514
FGG ITGAX â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10543983 17339034
CFD CFB â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 809512 279011
VDAC1 F11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CFI C4BPB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 293746 702059
C4BPA CFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 293746 702059
CFI CR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6214588 1386357
F2RL2 F2R â—¼   PROXIMITY 2.0 0.8 intact 17376866 0700763104
KRT8 F11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
C4A CD46 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12055245 2481448
CFI CD46 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6214588 1386357
VWF GP1BB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1939645 2010539
CD55 C4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6238120 8786315
CFI C4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 293746 702059
VWF GP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1939645 2010539
VWF GP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1939645 2010539
C8B C8G â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
F2 FGB â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
F2 FGG â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
F10 SERPINC1 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
C8B C9 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
MBL2 CR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23460739 29563915
C3 CFD â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
CR1 MASP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23460739 29563915
C1R C1QA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 2372546 10878362
CR2 CR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 1708808 7690834
C3 CFHR4 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
C3 CR2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
C3 ITGAM â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
F2 PROC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CFHR1 C3 â—¼   PHYSICAL_INTERACTION ✅ + 0.83 0.83 Signor 27814381
C1QC C1QB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21054788 16189514 12960167 28325905
APP F11 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
C8A C8B â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
C8A C8G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
GP1BA GP1BB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18674540 12693941 18789323 9325245
MASP1 MASP2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23785123 10878362
F8 VWF â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
APP CLU â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CFH CFI â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MASP2 MBL2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SERPINC1 F10 â—¼   CLEAVAGE ✅ - 0.87 0.87 Signor 31030036
MASP1 MBL2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
GP1BA GP9 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
KLKB1 KNG1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PROC PROCR â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
C1QB C1QA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14681455 21054788 12960167
KLKB1 KNG1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 291905 10464316 500690 17598838 7686159 7944388
F2 F5 â—¼   UP_REGULATES ✅ + 0.89 0.89 Signor 29880919
F10 F3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 3527261 3275472 6980899
F8 F10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9759621 10521497 12426309
C1R C1QA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QC C1QA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14681455 21054788 12960167 28325905
C1QA C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1QA C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
VTN C8G â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2465906 7542572 2466593
MASP1 MBL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11290788 32041782 20956340 27104295 10878362 21035894 19939495 22854970 18177377 25579818
MBL2 MASP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11290788 32041782 27104295 10878362 15117939 18177377 29209066
C4A MBL2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C2 MBL2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C3 CFI â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6607952 21788512 2971659
C1R C1QC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QC C1S â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QC C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1QC C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1R C1QB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QB C1S â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10904115 15388251 761607
C1QB C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1QB C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
KLKB1 HGF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10962009 12372819
F11 HGF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10962009 12372819
SERPINE1 PLAU â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11021826 20027185 25502501
PLG PLAU â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 2521625 2935528 1829461
PLAU PLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 3920216 2829380 4226004
SERPINE1 PLG â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11021826 20027185 25502501
C5 VTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2465906 7542572 2466593
C9 VTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2465906 7542572 2466593
VTN C8B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2465906 7542572 2466593
VTN C8A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2465906 7542572 2466593
VTN C7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2465906 7542572 2466593
VTN C6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2465906 7542572 2466593
FGG VTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16189514 2243140 11744726
PROS1 PROC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 1615482 2461936
C1S C1R â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31749804 10092586 2387866 9477945 33961781 10878362 2372546 12788922 17996945
C1S C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C1R C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1R C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
CFH CFI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26806831 9291131 1401896
GP1BA VWF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12183630 6336654 15039442 7690774 12087105 2690940
F9 GP1BA â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
C2 MASP1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C4A MASP1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
MASP1 C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11907111 10946292 11527969
F2RL2 F2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 873923 8615752 10079109
F2RL2 F2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 9618465 9087410 1672265
F2 F2RL3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 9618465 9087410 1672265
F2 F13A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9546612
F2 F8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18492805 10350471
F9 F11 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
F9 GP1BB â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
F9 GP5 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
F9 GP9 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
PROC F8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 1939075 1761551 16189514
KLKB1 SERPING1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 3756141 2579948 4178758
MASP2 C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
MASP2 C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
C5 C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1387399 2808363
C8A C9 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
C8A C9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10346902 3624872 4063341
SERPINA5 PROC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11123896 16189514
C4A CR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10531307 11694537 293688
CFI CR1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6607952 21788512 2971659
F12 SERPING1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 3756141 4703226 2578463
SERPINC1 F9 â—¼   CLEAVAGE ✅ - 0.9 0.9 Signor 31030036
C1QB C1QC â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
C3 VSIG4 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
PLAUR VTN â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CFH CFHR1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
F2 F2R â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
F2 GP1BA â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
F9 SERPINC1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
PLAT SERPINE1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
F2 SERPIND1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
F2 SERPINA5 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
F2 SERPINC1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
SERPINC1 F2 â—¼   CLEAVAGE ✅ - 0.94 0.94 Signor 31030036
C6 C8G â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C8B â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C9 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C8A â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
C6 C7 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
F2 F2RL2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
F2 F2RL3 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
C3 CR1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
C5 C8G â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
C1QA C1QC â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
F2 FGA â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
C5 C8A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
C5 C9 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
F2 THBD â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
FGB FGG â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
C1QA C1QB â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
SERPINE1 VTN â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
C1R C1S â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
C3 CFHR1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
C5 C6 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
C3 CD46 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
C5 C7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
C3 CFI â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
PLAU SERPINE1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
GP1BA VWF â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ITGAX ITGB2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
C3 CFB â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
C5 C8B â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
F3 F7 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
C3 CFH â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
FGA FGB â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
FGA FGG â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
F8 F10 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 2105717 1958666 2303434 7803238 1346975 26023895 3965513
F9 F10 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 2105717 1958666 2303434 7803238 1346975 26023895 3965513
FGA ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 4062888
C3 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 4062888 26293614
C9 C8G â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C8G CD59 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
MBL2 MASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22607836 9087411 20956340 22854970 10878362 21035894 25579818 27104295 19939495 32041782
MBL2 MASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11290788 9087411 15117939 10878362 27104295 22607836
CFI C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16023208 1401896 26806831 9291131 8648130 2141838
CFH C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 16023208 19050261 11367533 21979047 21317894 9988761 16612335
C3 C3AR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8702752 11342658 8765043 20527893 9476119
C3 CR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10382758 2551147 9988761 2141838
C3 ITGAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 4062888 16857732 7512600 7679388 12554829
C3 ITGAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 4062888 11073102 26293614
PLAU PLAUR â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
PLAU PLAUR â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
PLAU PLG â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 18633355 20027185 22470492 27216177
SERPINE1 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22449964 2544876 2161846 21199867 3090045 9184208
SERPINA5 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9365930 2752144 16189514
SERPINB2 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 2161846 2166055 8388810 16189514
PLAU PLAUR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 3031025 16879932 3023326 11501527 18376415 16189514 19017363 16456079
VTN SERPINE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11113116 12808446 11796824 8830783 16713569 9065424
SERPINE1 PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 2110366 16713569 8607113 3090045
SERPINF2 PLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 3334852 134998 158022 2437112
PLG F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10978167
PROS1 F5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10593904 8428962
SERPING1 C1S â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9882449 17488724 3756141 28742139 6604523
CFHR1 CFH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8663389 16189514 27814381 19528535
F11 GP1BA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12391017 3017409 11696542 1730602
F2 GP1BA â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F12 GP1BA â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
VWF GP1BA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17145710 19286885 15039442 6336654 12087105 7690774 12183630 2690940
F2 FGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25241761 2133223 2742826 1587268
FGA PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 3088041 11170397
FGA ITGAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 4062888 7679388
F8 F2 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 19240027 8052958 2104766 15705787 1851341 2109644 1973901
F2 GP1BB â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 F11 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 VWF â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 19240027 8052958 2104766 15705787 1851341 2109644 1973901
F2 GP9 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 GP5 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
SERPINC1 F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 3800906 2013320 28743742 11927130 31030036 7238875
F2 THBD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 14691232 7615164 2544585 8663147
F2 F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9058715 10978167 15707890 10644723 14652070 11356985 23450633 18250335 12563219 22972936
F2 F2RL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1273221212732210 12732212 22318735
F2 F2RL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11356985 12732212 1135698512732210
F2 GP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 2207326
F2 F5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10026263 9032460 29880919
VWF F8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18492805 9218428 27749002 3134349 23020315
KNG1 KLKB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14996700 12123826 11830581 8344943
F12 KLKB1 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 30394658 30591525 27130860 6604055
KLKB1 KNG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 3650269 500690 7944388 10464316 7686159 27006387 28966616 291905
C5 CD59 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C5 C5AR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 9881961 11773063 9553099 15661745 10602324 1847994
C9 C8B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C8B CD59 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C9 C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C6 CD59 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
C9 C8A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
F7 F3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 25241761 15664864 8940045 9414278 9925787 15522303 8598903 12787023
PROC PROCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 7929370 11099506 10681521 16189514
PROC THBD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12588872 11106601
PROC F5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10026263 1615482 7989361 29880919
KNG1 BDKRB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18127230 3366244 8063797 1314587
KNG1 BDKRB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18127230 3366244 8063797 1314587
F12 KNG1 â—¼   CLEAVAGE ✅ 8.0 1.0 Reactome 3886654 874082 11204562 6604055 11986212 1066663 14691562 7391081
KNG1 BDKRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 9313952 8856107 8735629 9111052 8063797 10422787
KNG1 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9203620 8063797 8302267 28966616
F11 GP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12391017 3017409 11696542 1730602
F11 GP1BB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12391017 3017409 11696542 1730602
F11 GP9 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12391017 3017409 11696542 1730602
F12 F11 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
F12 GP9 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
F12 GP5 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
F12 GP1BB â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
C7 CD59 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145
CD59 C9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 7523406 1377690
C9 C7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145