Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FLNA CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK GP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ETS1 SPRY2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14644509
KLF1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12556498 18523154
KLF1 FLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12556498
FLI1 KLF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12556498
GP1BA FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11700320 3155520
VWF FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11700320 3155520
GP1BB FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11700320 3155520
GP9 FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11700320 3155520
FLNA YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
FLNA PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FLNA GP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11700320 3155520
GATA1 GP1BA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17725493 12724402
YWHAZ GP1BA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19558434 8009025
VWF GP1BA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215664 12183630
VWF GP1BB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1939645 2010539
VWF GP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1939645 2010539
VWF GP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1939645 2010539
HOXA1 VWF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
YWHAZ PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10887121 8009576
GP1BA GP9 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HOXA1 SPRY2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CRK PIK3R1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
GP1BA YWHAZ â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
VWF CRK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
ETS1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11991951 19829305
ETS1 VWF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9444957
F9 F11 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
F9 GP1BA â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
F9 GP9 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
F9 GP1BB â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
F9 GP5 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 29223926 22961984 11342438
GATA1 FLI1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10364157 12556498 12724402 16189514
GATA1 GP1BB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11418466 8703016
GATA1 KLF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20564185 8195185 18487511
ZBTB16 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
F2 GP1BA â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
FLNA GP1BA â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
GP1BA VWF â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CRK PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
PIK3R1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
CRK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
ETS1 GP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15466856 11504709 10194443
F11 GP1BB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12391017 3017409 11696542 1730602
F11 GP1BA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12391017 3017409 11696542 1730602
F2 F11 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F11 GP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12391017 3017409 11696542 1730602
F12 F11 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
F11 GP9 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12391017 3017409 11696542 1730602
F12 GP1BB â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
F12 GP9 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
F12 GP1BA â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
F12 GP5 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 1998667 588558 893417 10781579
F2 GP5 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 GP1BB â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 GP9 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 GP1BA â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 VWF â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 19240027 8052958 2104766 15705787 1851341 2109644 1973901
F2 GP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 2207326
FLI1 GP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15466856 12556498 10194443 12724402
FLI1 GATA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8510925 20110178 21205096 12724402
FLI1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12556498 12724402 16189514 10364157
VWF GP1BA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17145710 19286885 15039442 6336654 12087105 7690774 12183630 2690940
GP5 YWHAZ â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8034572 9425086 10627461 8631758
GP9 YWHAZ â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8034572 9425086 10627461 8631758
VWF YWHAZ â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8034572 9425086 10627461 8631758