Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PPL SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
VIM SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PICK1 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PPL USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
VIM DES â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
HTT DES â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DES VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32296183 27107012
PBX4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LETM1 PPL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPM PPL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 PPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19583808
KRT8 PPL â—¼   COLOCALIZATION 2.0 0.8 intact 8388011 22841549
PPHLN1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
VIM KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HTT EZR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19164283
TRAF2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 TGM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10886517 21248772
HTT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KNSTRN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PICK1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TGM1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PBX4 PPL â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
ACTR5 PPL â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
PPL ZNF165 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
KRT25 PPL â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
ACAD9 EVPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FCF1 EVPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FRMD1 EVPL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DES PPL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
RBM24 EVPL â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TRIM27 USP7 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
KCTD21 PPL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
PPL ZNF263 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
PPL ZBTB26 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
ZNF165 ZNF263 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
KRT39 PPL â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
DES VIM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
SP1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17663720 22227038 3419902 10777586 12771217
CASP6 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11423904 10469173 11514563
AKT1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20856200
SP1 EZR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21628504 19164283
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
SP1 IVL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15191537 16374477 17882273 15025563 9512462 9895295
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893