Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
LETM1 PPL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PBX4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NMES1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TGM1 CASP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDH1 EPCAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKD1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15695390
TUBB CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VIM DES â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
HTT DES â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DES VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32296183 27107012
VIM ESRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT EZR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19164283
HNRNPM PPL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TRAF2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PICK1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KNSTRN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKD1 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26580203 22357621
VIM KRT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KRT8 PPL â—¼   COLOCALIZATION 2.0 0.8 intact 8388011 22841549
SP1 MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18173747
PICK1 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PPHLN1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
PPL USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PPL SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SP1 PPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19583808
S100A16 S100A14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VIM SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 TGM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10886517 21248772
TUBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EPCAM LSR â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PBX4 PPL â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
LAD1 PKP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CDH1 PKP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
C6orf132 PKP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ESRP1 GRHL2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PKP3 ST14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EPCAM PKP3 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ACTR5 PPL â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
GALNT3 SPINT1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PPL ZNF165 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
PKP3 SPINT1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
LAD1 ST14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
KRT25 PPL â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
EPCAM LAD1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CDH1 ESRP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
FCF1 PKP3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ACAD9 EVPL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FRMD1 EVPL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FCF1 EVPL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FRMD1 SCEL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DES PPL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
ESRP1 SPINT1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EPCAM ESRP1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RBM24 PKP3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RBM24 EVPL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TRIM27 USP7 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
KCTD21 PPL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
PPL ZNF263 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
PPL ZBTB26 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
ZNF165 ZNF263 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
EVPL PPL â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CDH1 EPCAM â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
RAD18 TRIM27 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
EPCAM ST14 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EPCAM SPINT1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
KRT39 PPL â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
EZR MISP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
SPINT1 ST14 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CDH1 SPINT1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
SPINT1 ST14 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
DSG2 DSC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11853539 21220045
ESRP1 ST14 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
DES NEFH â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
BAIAP2 KIAA1522 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AKT1 CHUK â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDH1 ST14 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CHUK TRAF2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
LAMB3 LAMC2 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
DES VIM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
SP1 CDH3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19882246 9328434
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
LAMB3 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12867433 8143784 32196115
SP1 SIGIRR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21077278 24821721
NEFH VIM â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
DES VIM â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
EXO1 PPL â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
S100A14 S100A16 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
MDC1 FTH1 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
SP1 IVL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15191537 16374477 17882273 15025563 9512462 9895295
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
AKT1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20856200
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 15710601 12048203 25241761 19442713 11278366 10485711 15800029 19609947 17570479 17660512 18515365 19088076 10485710
DNM2 AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 AP1M2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
CASP6 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11423904 10469173 11514563
TRAF2 CHUK â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26587781
TRAF2 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15725726 12547194 11359906 25241761 20449947 9244310 16713569 23007157 10795740 24323043 19150425
SP1 EZR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21628504 19164283
ROCK2 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8522586 20737283 9456324 9287351 10970850 12778124 12045227 12802084 7579708 10047517 8527459
LAMC2 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12867433 10842354 8143784
PRKD1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19651622 8885868 20068231 1370476
SP1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17663720 22227038 3419902 10777586 12771217
RAD18 PPL â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
MDC1 PPL â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
XPA PPL â—¼   KO_DOWN_REGULATES ✅ - -1.87 1.86 PKG 28854368
RAD18 VIM â—¼   KO_DOWN_REGULATES ✅ - -1.95 1.94 PKG 28854368
MDC1 VIM â—¼   KO_UP_REGULATES ✅ + 2.11 2.11 PKG 28854368
MDC1 CDA â—¼   KO_DOWN_REGULATES ✅ - -2.82 2.81 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368