RPN1
|
SIGIRR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SIGIRR
|
MYD88
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20364327
15866876
|
SIGIRR
|
ENO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
IL37
|
SIGIRR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25729923
|
TRAF6
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
31594754
30711629
31754475
30806153
|
TIRAP
|
MYD88
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
5220054
17583698
|
IL1R1
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12496252
20064081
18996842
12242293
16286467
12609980
|
MYD88
|
IL1R1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24735611
9374458
9575168
10854325
22904187
12659850
12609980
|
TIRAP
|
IRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33961781
21903422
|
TIRAP
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
TIRAP
|
TLR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
IL1R1
|
IRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24735611
8599092
12242293
22904187
16024789
12609980
|
IL1R1
|
MYD88
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
MYD88
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23831471
28404732
16517750
|
TIRAP
|
MYD88
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
28483816
17258210
11544529
18221795
20048342
24316379
33961781
17583698
21334391
|
TIRAP
|
TLR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11526399
17258210
11544529
18221795
20048342
21829704
21903422
|
IRAK1
|
TLR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9625770
17635639
|
SP1
|
SIGIRR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21077278
24821721
|
IL37
|
IL18R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12096920
25654981
|
TRAF6
|
IRAK1
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
18347055
|
MYD88
|
TLR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
IL1R1
|
IRAK1
|
â—¼ UP_REGULATES
|
✅
|
+
|
0.92
|
0.92
|
Signor
|
14625308
|
MYD88
|
IRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
17567694
11544529
33052227
22011580
11960013
16951688
16024789
12538665
12034707
21903422
17920759
31776466
16461741
10383454
21179087
17276401
11976320
17548806
10854325
|
IRAK1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.96
|
STRING
|
36370105
|
TRAF6
|
IRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
22033459
24735611
11397809
19716405
17197697
30872404
8837778
10346818
17785851
11960013
18234474
16951688
16024789
11287640
12034707
21220427
23381138
19166926
24434549
28882891
18056395
11259596
23244239
12496252
22447928
20043910
12566447
11518704
12242293
10920205
10383454
18347055
9374458
31921110
14625308
|
TLR4
|
MYD88
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
17126326
15107846
10952994
17258210
18221795
20048342
15728506
33052227
12646618
11743586
21911421
21829704
|
IRAK1
|
MYD88
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
MYD88
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11274345
12620219
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
TRAF6
|
IRAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
11274345
12150927
12620219
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
TRAF6
|
IL1R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11274345
12620219
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
MYD88
|
TRAF6
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11274345
12620219
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
TRAF6
|
IRAK1
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
11274345
12150927
12620219
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
TRAF6
|
IL1R1
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11274345
12620219
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
TRAF6
|
IRAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
11274345
12150927
12620219
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
IRAK1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
10346818
17145710
17785851
16024789
14625308
11259596
10383454
18234474
9374458
11287640
23244239
21220427
11518704
19166926
16951367
15894263
10747026
35926385
18056395
12566447
12496252
22447928
12242293
8837778
10920205
11960013
19716405
24735611
20043910
24434549
17785432
11397809
18347055
22033459
12140561
23381138
17197697
|
IL1R1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17145710
12242293
15866876
16286467
16286016
12609980
16354686
|
TIRAP
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15247281
21873236
19592497
24084649
|
MYD88
|
IL1R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
11274345
12620219
12682231
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
IL1R1
|
IRAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
11274345
12620219
12682231
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
MYD88
|
IL1R1
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
11274345
12620219
12682231
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
IL1R1
|
IRAK1
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
11274345
12620219
12682231
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
IL1R1
|
IRAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
11274345
12620219
12682231
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
IL1R1
|
MYD88
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15866876
19940113
9430229
10217414
12659850
16286016
15905496
17507369
12609980
16354686
|
IL1R1
|
IRAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12242293
23331499
15866876
9430229
9374458
16024789
14625308
15905496
16286016
8599092
12609980
|
MYD88
|
TIRAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16267105
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
MYD88
|
IRAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
MYD88
|
IL18R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
MYD88
|
IRAK1
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
MYD88
|
IL18R1
|
â—¼ SHARES_COMPLEX
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
MYD88
|
TIRAP
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16267105
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
MYD88
|
IRAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
TIRAP
|
MYD88
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
22673208
19506249
11544529
20048342
16410796
21334391
17258210
24316379
25948473
24265315
18221795
12888566
16189514
21873236
11526399
28483816
17583698
|
TLR4
|
MYD88
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
22664090
19717524
20048342
21911421
9625770
17228323
17258210
11743586
15107846
15728506
12888566
21829704
18221795
10952994
17635639
17126326
12646618
|
MYD88
|
IRAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
17145710
10383454
16951367
12538665
21903422
9430229
12360211
11976320
17228323
19775907
16024789
17276401
17785432
17567694
10854325
10217414
17920759
16461741
|
TIRAP
|
IRAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
TLR4
|
TIRAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
17145710
22139835
19717524
11544529
20048342
21903422
16410796
17258210
14517278
24265315
21829704
18221795
17635639
21873236
11526399
12646618
|
TLR4
|
IRAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
21606490
11544529
17890055
19679662
20485341
17878161
16024789
19224918
20400509
|
IL18R1
|
IRAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
IL18R1
|
IRAK1
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
IL18R1
|
IRAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|