Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CDK2 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25558984 22231403
CDKN2A CDK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDKN2A CDK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CTBP2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19798104 23255392
TWIST1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22290439 20818389
CDKN2A KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16915296
CHEK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5218401 16511572
COPS5 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TCF7L2 COPS5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
PARP1 CUL4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
DHX9 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
CREB3 EMD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
EP300 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22000024 19419955
EP300 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828133 24058639
TP73 EP300 â—¼   ACETYLATION ✅ 2.0 0.8 intact 11804596 5215037
EP300 DDX17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20663877
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
CREB3 HMOX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TP53 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24366007 21552291
TP73 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14614455 21245298
KLF12 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 HNRNPF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SIRT1 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20100829
KLF3 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
CDCA5 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
NPM1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219698 17318229
PARP1 RNH1 â—¼   COLOCALIZATION 2.0 0.8 intact 8086497 21276451
CHFR PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18172500 23268447
CSNK2A1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20711232
HSPA8 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19229036 23349863
HSPA1A SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19229036 23349863
SMAD3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
SIRT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27776347 28583374
SIRT1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16998810
SIRT1 PER2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18662546
MYOD1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17194702 17043109
SMARCA4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11950834 33476981
USP29 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8145365 21285945
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
TP53 HSPA1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
TP53 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
TP53 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22103682 8291914
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
YBX1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12835324 16963428
TP53 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21900401
TP53 TWIST1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18504427 20689556
TP53 TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14990988
TP53 YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18504427 22417301
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
HOXA5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19918835
TP53 SERPINE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 SERPINB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
MYOD1 TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10835425 9448005
TP73 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19815500 0905867106
TP63 SERPINB5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15578720 15466179
MYOD1 TP73 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18513743 16007124
TP73 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11309270 18829110
TWIST1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22056872 8313152
USP10 USP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21962518 22216260
USP7 CHFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17442268
SMAD3 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
XRCC6 CDCA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XRCC6 RPLP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XRCC6 SMAD7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
HDAC1 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16464847 24058639
MYB COL1A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9989795
HOXA5 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10875927
CDK6 RBL2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11157749 9144196
C1QBP HNRNPF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CRKL SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
PAX6 CRYBB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9710641 14707122
SMAD7 MYOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
CTNNB1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18948405 15031118
SMAD3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11711431
SMAD7 TGFB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10519551 19758997
SMAD7 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15684397 1568439
SMAD7 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18762808 17438144
TGFB1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21358634 9679059
PPP2R1A SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ZEB2 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD2 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD2 RPS14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD2 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15292219
RPLP0 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
SMAD3 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD3 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15240008 15623506
SMAD3 GLI2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19797115
SMAD3 ACTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20123992 12702545
SMAD3 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15292219
TGFB1 COL2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 10085302
ZEB2 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
HDAC1 GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
KLF8 CTBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17671186 19798104
KLF8 CTBP2 â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 17671186 19798104
KLF3 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18687676
CREBBP GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
TCF7L2 GLI2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19797115
EHMT2 LMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LMO2 DRAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CTNNB1 LMO2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592430 12782598
CBX4 BMI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17332741 5219708
PPP2R1A CDK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
CDK4 CCND2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CDK4 RBL2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11157749 9144196
UCHL3 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21453705 8149649
TUBA4A SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219486 17183365
SMAD1 CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18668566 20522428
SMAD1 SATB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
SMAD1 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12082094 12151083
MRPS35 DAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CREB3 RPS3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CREB3 SLC2A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CREB3 FXYD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
HNRNPM RPL7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCND2 RBL2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11157749 9144196
SSB NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18292223 0712387105
NCL MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10660576
CTNNB1 CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20571031 12200448
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
UBE2O SMAD6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8429180 23455153
UBE2O SMAD6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23455153
SERPINH1 SERBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF12 EHMT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LCOR EHMT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PGR GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19423654 22669741
NFIX ETV5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
ZNF516 CTBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 28947780
CTBP1 ZNF516 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 28947780
MYB PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9371644 7838532
ZNF217 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18625718 22560925
DDX5 SYNCRIP â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
SMAD1 DDX5 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18548003
DDX17 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 17226766 19995069 33742100 20663877
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
EP300 PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18280497 16204234 19622798 12960163 24636898 33742100
TP53 HSPA9 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5219502 17184779
CTBP1 ZEB1 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
E4F1 DDX21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DDX5 DHX9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 26344197
DHX9 XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15723802 30585729
CTBP1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21102443 15834423 35016035 16122695
EP300 KLF8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
SMAD2 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22995475 15009097 11058129 34576109
SMAD3 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22995475 15009097 11058129 15994459
KAT2B KLF8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
KAT5 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27295567 16169070
SOX2 KDM1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30442713 28794006
BMI1 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20668194 34316702
PARP1 ZEB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 34462429
E4F1 C1QBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
C1QBP PTCD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 22904065
BMI1 ILF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
HDAC2 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30737378 26949739
KLF8 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21416054 35140242
BMI1 ILF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 RTCB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 G3BP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 G3BP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
E4F1 UBE2O â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E4F1 PTCD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
REST EHMT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17468742 15200951
SOX2 TEAD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
ATM CHEK1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 20068082
G3BP1 HSPA9 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
TP53 YBX1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
GLI2 SUFU â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
FUS SYNCRIP â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
DHX9 XRCC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15723802 14704337 21679440
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
SOX2 XRCC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21280222 35140242 23667531
BMI1 XRCC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20668194 24457600 34316702
ZEB2 SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15231748 12714599 10400677 16061479
ZEB2 SMAD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22365546 15231748 12714599 10400677
HDAC1 RREB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 33961781 26496610
HDAC1 EHMT1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
CCND2 RBL2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
KLF12 EHMT2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 16189514 35140242
EHMT2 CTBP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 17967884 31041561 16702210 33961781 26186194
EHMT2 KLF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 35140242
CTBP1 KLF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27107012 35140242 24722188
CTBP1 RREB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 17967884 33961781 35016035 26186194
CTBP1 RCOR3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31041561 33961781 26186194
LHX6 SATB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TP53 USP10 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CSNK2A1 HDAC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CTNNB1 SMAD3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
RCOR1 REST â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
HDAC1 SMAD2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
EP300 ILF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20808282 33742100
EP300 XRCC6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15023334 33742100 21988832
PRKDC PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16794079 9398855 21575865 20085707
FUS ILF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27460707 29884807
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
CTBP1 ZEB2 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
EHMT1 CTBP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 31041561 16702210 33961781 26186194 12700765
SMARCA4 TP53 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
KAT2B SMAD3 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CDYL HDAC2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
C1QBP YBX1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CDK2 RBL2 â—¼   PHOSPHORYLATION 0.85 0.85 Signor 11157749
CUL4B HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618
CUL4B HDAC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30737378 34026424 25189618
FUS DHX9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27460707 29884807
ILF2 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
EP300 PRKDC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
EP300 SMAD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10205054 20851880 22365546 16613856 10673036
PARP1 HDAC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 16204234 20596014
CRKL SOS1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9162067 26496610 33961781 32203420 23397142
SMAD2 HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10199400 11226163 31130994 14699069
RBL2 CDK4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22094256 33961781
FUS DDX17 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27460707 29884807 26344197
KLF12 CTBP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25416956 11373277 35140242 24722188 27107012
CRKL USP53 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
RPS3 SERBP1 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CCND2 RBL2 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CSNK2A1 SIRT1 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
SMAD1 SMAD6 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
ATM PRKDC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10608806 10464290
CDK2 TP53 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24173284
CUL4B DHX9 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
CUL4B PRDX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
CUL4B DDX5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
KLF3 KDM1A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 23455924
PPM1G PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 27880917
PARP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 16204234 20596014 19470756
EHMT2 HDAC2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21258344 26028330
HDAC2 RREB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23752268 21258344
FUS HNRNPR â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
SOX2 EHMT2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
FOXL1 SATB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 25609649
E4F1 TP53 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CCND2 CDK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9840943 28514442 33854235 33961781 26186194 23455922 9178893
C1QBP DDX21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 32877691 28565870
DHX9 ILF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22863883 22939629 23986595
CTBP1 KAT2B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15834423 9824164 16122695
KAT2B MYOD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20364308 9659901 27453350 17964260 10944526 10619020 12887892 17468105
EHMT2 KDM1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26028330 26751641
KDM1A RREB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 23752268 16140033
KDM1A CTBP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 17967884 31041561 28947780 20547759 26496610 33961781 26186194 16140033 16079794
PPM1G USP7 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
PPM1G XRCC6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30585729 28330616
RCOR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 17967884 19242095 31041561 28947780 33961781 26186194
XRCC6 ILF3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31536960 30585729 21969602
SMAD7 SMAD6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26555259 9256479
ZEB2 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34026424 18182442 26028330
HDAC1 REST â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18806873 10491605
HDAC1 EHMT2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 26028330 26496610 33961781 16287849
HDAC1 E4F1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12730668 21666599
HDAC1 RCOR3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 26496610 21258344 33961781
G3BP2 G3BP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 26777405 26186194 29395067
DDX17 DDX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SYNCRIP YBX1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
KAT5 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
G3BP1 PABPC1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
G3BP1 G3BP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CBX4 CTBP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EP300 NAP1L1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HSPA9 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
COPS5 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CHFR PARP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CHEK1 TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EP300 TP73 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
KDM1A ZNF217 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
NPM1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CTBP1 ZNF217 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SMAD2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
FUS EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18509338 30110629 33742100
EP300 MYB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20364308 11585920 29954426 15691758 35140242 10656693 25740244
EP300 SMAD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11371641 21988832 10199400 12237408 11264182 15623506
PRKDC ILF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20808282 9442054 21969602
CDK4 CDK6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23455922 28205554 28628118 33961781
MYOD1 CDK4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10601020 10022835
SMAD2 SMAD1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9111321 28628118 18729074 28205554
ZEB2 CTBP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31041561 33961781 12714599 26186194 24722188 16061479 35016035
ZEB2 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34026424 18182442 26028330
CTBP2 LCOR â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CBX4 CTBP2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 16189514 9858600
DDX1 RTCB â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
SMAD6 CTBP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14645520 24850914
RCOR1 ZNF217 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTBP1 CTBP2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 MYOD1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
C14orf166 RTCB â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PRKDC TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
XRCC5 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
NCL NPM1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
HSPA8 HSPH1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CREBBP KAT2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SIRT1 TP53 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CTBP1 KDM1A â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CREBBP SMAD3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HNRNPU SYNCRIP â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HDAC2 SMARCA4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CREBBP SMAD2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CSNK2A1 HDAC2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
SMAD3 DDX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15464984 18548003 19917253
HDAC1 DDX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20663877 20022962 15298701 19995069 17369852
ILF3 DHX9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22751105 12946349 31536960 23986595 22939629
KAT2B EP300 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8684459 12888487 9267036 12419806 21413932 22384255 20870727 33051058
EP300 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 10506141
KAT2B MYOD1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
HDAC1 KDM1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16079794 19703393 21258344 34050636 11102443 27183383 16140033 21937684 12032298 26496610 22143567 19497860 11171972 17634443 12493763 20856864 20585571 31130994 21670149 26344197 23752268 32882276 17687328 33961781 24981860 28667074
ILF2 PRKDC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20808282 17389650 9442054
CDK6 CDKN2B â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
HDAC1 MYOD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11285237 11684023 16713569 20124407
DDX17 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 15298701 19995069 20663877
HDAC2 CTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17967884 31041561 16713569 28947780 16036112 10766745 18212045 11022042
HDAC2 RCOR3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23752268 21258344 24981860 26949739
SUFU GLI2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12068298 35140242 33961781 10564661
CTBP2 LCOR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 25416956 27705803 12535528 33961781
CTBP2 CTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31041561 16189514 25416956 16713569 21988832 28947780 30585266 26496610 33961781 35016035 26186194 24722188 27107012 9858600 26344197
SMAD6 SMAD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11483516 12857866 9436979 9256479
RTCB DDX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24608264 22863883 33961781 27173435 24981860 29395067 22939629 30833792 26344197
ILF3 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27460707 29884807 16713569 11438536
EHMT1 EHMT2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
EHMT2 EHMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21430779 26028330 27705803 21258344 24981860 34588438 28698370
SRF TEAD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11136726 12061776
CTBP1 LCOR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31041561 20211142 12535528 27705803 33961781 35016035 26186194 24722188
CDKN2A NPM1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CDK4 CDKN2B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
ASUN VWA9 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CDK2 RBL2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CDKN2A TP53 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
KAT5 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16141325
RBL2 CDK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9891079 17531812 25852190 9472014 33961781 26186194 23602568 10825149 23455922 9188854
CDK2 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26186194 10330164 23455922
CDK2 PRDX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11986303
NEUROD2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
CREB3 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
PAX6 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20053773 11584062 17157287
DDX5 FUS â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
DDX5 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 33742100 12527917
EP300 DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12527917 20663877
EP300 MYOD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20364308 12665587 20037778 17964260 35140242 10944526 9862959 9001254 8621548
RCOR1 KDM1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19703393 21258344 34050636 11102443 18806873 16140033 12032298 22143567 20389281 11171972 21300290 16885027 21602794 26226427 21142040 21670149 26344197 24217620 32882276 20164337 28667074 17687328 33961781 27173435 24981860 34079125 34031383 16956976 16079794
KDM1A RCOR3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 21258344 23455924 24981860 34079125 26344197
KDM1A HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 32882276 19703393 9804427 12032298 20164337 28667074 26949739 34031383 21258344 26344197 34050636 21670149 24981860 11102443 12493763 16079794 21937684
PARP1 XRCC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24140708 16490787 16794079 14734561 33961781 30585729 34079125 10400681 17283121
PARP1 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24140708 16490787 21575865 16794079 14734561 21679440 34079125 10400681 17283121 20085707
XRCC5 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15941674 10750018 20023628 17308091 15758953 20085707 33005030 10446239 26496610 19303849 20711232 9312071 26446488 15520013 28154079 28345663 16857680 12393188 22404984 21679440 26344197
XRCC6 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20711232 21575865 33005030 28345663 15941674 10064605 26496610 26446488 15520013 10750018 8422676 26175416 22939629 17308091 30585729 19303849 21969602
RCOR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 17939992 19703393 12032298 26496610 17938259 21258344 33961781 15897453 19497860 12192000 11602581 11171972 17956988 18806873 11102443
RCOR1 HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 12032298 30737378 26949739 21258344 33961781 24981860 12192000 11171972 11102443
SMARCA4 TCF7L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19571879 11532957 21654818
TP53 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17003465 24192518 16917063
TP53 HNRNPR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TP53 AIFM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23506862 16729031
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
TP53 EPCAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19141643
TP53 SLC25A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24076372 9671769 12080472
HSPA1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
TP53 HSPA1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
TP73 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16413471 21436470 18026135
TP63 AHCYL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
TP63 KLF12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
TP63 CDC25C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19861536
TP73 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11238924 19815500 10373484
XRCC6 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15910003 19177010 28514442 28035050 14681455 10750018 17159921 25574025 17308091 10984620 11196700 32296183 7699019 33005030 15367688 12145306 19118032 10446239 26496610 19906305 26774286 10207052 21454661 18809223 9488450 26446488 15520013 30021884 22939629 17283121 10219089 10757784 21070772 11493912 21172662 15023334 22863883 22451927 21679440 24981860 10783163 33961781 30585729 26344197
YBX1 SMAD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12917425 12446674 16278212
YBX1 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12446674 12917425 16278212
CDK6 CCND2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 28628118 10022865 28205554 11360184 30217970 33961781 23602568 11358847 9178893
CDK6 PRDX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11986303
SERPINE1 PLAU â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11021826 20027185 25502501
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SMAD2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27974707 11456453 16284942
HDAC1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10199400
SMAD2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18729074 9111321
SMAD3 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055503 24416423
SMAD6 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9892110
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
ZEB1 GRHL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23943797 23814079
CTBP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 9650586 16189514 23752268 31041561 16713569 28947780 10995736 34147029 18765668 11022042
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
CTBP2 KLF8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 35140242 10756197
SUFU GLI2 â—¼   PHYSICAL_INTERACTION ✅ + 0.9 0.9 Signor 20463034
SUFU GLI2 â—¼   RELOCALIZATION ✅ - 0.9 0.9 Signor 16316410
GLI2 PTHLH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16885353 19759178 21868511
MYB LMO2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20686118
CBX4 BMI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282530 22078878 9199346 34316702 18453536 20601937 19636380 26496610 27705803 22325352 27647897 33961781 24981860 17332741 24457600 12829790
CDK4 PRDX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11986303
KLF3 CTBP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9724649 35140242 32296183 12556451
RPS6KA5 SMAD6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CBX4 CTBP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15592428 20098713 33961781 20361981 12679040 26186194 11583618 9858600 12829790
GATA2 LYL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
DDX17 FUS â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CCND2 CDK2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
MRPS27 MRPS35 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
MRPS27 PTCD3 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
DAP3 RPS18 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
KAT2B TP53 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HDAC2 RCOR1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HSPA4 HSPA8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
ILF2 ILF3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CREBBP CTNNB1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
BMI1 CBX4 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
CDK4 CDKN2A â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
HDAC1 RCOR1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
DHX9 PABPC1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
RPS15A SERBP1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
RPL7 SERBP1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CCND2 CDK6 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
RPL3 SERBP1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
MRPS35 PTCD3 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
CTBP2 ZEB1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 9724649 16713569 34462429 25086746 12714599 10567582 19754958 10359772
HDAC1 RBL2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 9858615 9724731 10969803
CCND2 CDK4 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
RPS14 SERBP1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RPL3 RPS3 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
RPL23A SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS16 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS2 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPLP1 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPL7A SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS18 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPL6 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS13 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPLP0 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS9 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS3A SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS4X SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS8 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
DDX17 DDX5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 22365833 15298701 19995069 22863883 33961781 24581491 10837141 22939629
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219440 17159921
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
ILF3 ILF2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 16189514 20808282 23986595 33961781 17389650 26186194 29395067 22939629 26472337 11739746 21969602
CTBP1 ZEB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 17967884 31041561 34462429 25086746 33961781 10567582 26186194 35016035 10359772
HDAC2 KDM1A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
DAP3 MRPS27 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
RPS6 SERBP1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
RPL4 SERBP1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CHEK1 TP53BP1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
RCOR1 REST â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10449787 17939992 15897453 25197063
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
CDKN2B CDK4 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 21900206 2001699 8089645
DAP3 PTCD3 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
TCF7L2 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 11713475 5214798
C14orf166 DDX1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
CDC25C CHEK1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
PLAU SERPINE1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
G3BP2 USP10 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CREBBP MYB â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
AHCYL1 AHCYL2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
G3BP1 USP10 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
KDM1A RCOR3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
RPS18 RPS3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
RPL14 RPLP1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CDK6 CDKN2A â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPL7 RPS3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
TP53 TP53BP1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL3 RPS9 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL3 RPS18 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL6 RPS3 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPL3 RPLP1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPL3 RPS14 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPS16 RPS3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPS14 RPS3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPS15A RPS3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPLP1 RPS3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL23A RPS3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPL4 RPS3 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPLP1 RPS9 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL14 RPS3 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
CCND2 CDK4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 16189514 14681455 32296183 9325318 11360184 30217970 28205554 15169570 10022865 17873913 25910212 27107012 28628118 33961781 26186194 11896535 9178893 11971966
RPL3 RPL4 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RPL14 RPL3 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RPL23A RPL3 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RPL3 RPS2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RPL7A RPS3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL3 RPL7A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL3 RPS6 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL3 RPL6 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL3 RPS8 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL3 RPS16 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL3 RPLP0 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL3 RPS13 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL3 RPS3A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPLP0 RPS3 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RPL3 RPS4X â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RPL3 RPL7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RPS2 RPS3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS13 RPS3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS3 RPS9 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS3 RPS4X â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS3 RPS3A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS3 RPS8 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS3 RPS6 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL3 RPS15A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL7 RPS18 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPLP0 RPS18 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPLP0 RPS9 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPL14 RPS14 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
KDM1A RCOR1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DAP3 MRPS35 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL4 RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL14 RPS9 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL14 RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23A RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPS15A RPS9 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL7 RPLP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL7 RPS9 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL6 RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL4 RPLP0 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL4 RPS15A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL23A RPLP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS16 RPS18 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL6 RPS15A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS15A RPS18 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL7 RPS2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL7 RPS13 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL7 RPS4X â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL7 RPLP0 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL7 RPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS18 RPS2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL6 RPS2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL6 RPLP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP1 RPS18 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP1 RPS14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL7A RPS18 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL6 RPS14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS14 RPS18 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS13 RPS18 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS18 RPS9 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS18 RPS3A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS18 RPS8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS18 RPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL6 RPLP0 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL6 RPS3A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP0 RPS13 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP0 RPS8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP0 RPS4X â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL23A RPL4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS9 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPLP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPL6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL23A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPS15A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS15A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS9 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPLP0 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPL6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPLP0 RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL6 RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7 RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPLP1 RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS16 RPS9 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS16 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS15A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7 RPS15A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPLP0 RPS15A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPLP1 RPS15A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS13 RPS15A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS14 RPS15A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS15A RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS15A RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS15A RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS15A RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL6 RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7 RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7 RPS14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS14 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS2 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS2 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPLP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPLP1 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPLP1 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPLP1 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPLP1 RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS9 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPLP0 RPS14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS14 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS18 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL6 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL6 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL6 RPS9 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL6 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPLP0 RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS3A RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CTNNB1 TCF7L2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS4X RPS9 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL14 RPL4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL4 RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL14 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL14 RPLP0 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL23A RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS15A RPS16 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS14 RPS16 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS16 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS16 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS16 RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS16 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS16 RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS15A RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPLP1 RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPLP0 RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS2 RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS2 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS2 RPS9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPLP0 RPLP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPLP1 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL6 RPL7A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL7A RPS14 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL7A RPLP0 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL7A RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS14 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS14 RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS14 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS14 RPS9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS14 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL6 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPLP0 RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS4X RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS6 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS6 RPS9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS8 RPS9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS3A RPS9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS3A RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS3A RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS4X RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
CDK2 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9781043 16322221 16123081 11292842 10928988
ATM CHEK1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM PARP1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24366874 20023394 18769144
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
ATM SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22588298 23277204
ATM PPM1G â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26324325 17525332
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
ATM CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 69.0 1.0 Omnipath 29774099 20976184 26683224 25663895 12676583 17303408 14657349 29167438 27545311 10859164 19056039 15485915 28808226 12588868 16163361 15650047 12676962 17570479 14988723 14681223 26516160 10608806 26069190 29741650 12676925 23847781 17118344 11252893 20376879 15964794 15149599 18691976 19059218 20068082 15707391 12607003 25450480 17525332 11553781 19646247 15870257 15459660 20798862 19716789 11877377 12660173 11390642 15674326 16782033 28396830 28228262 12446774 15533933 15212693 29555944
CDK2 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10197981 11283614 12193595 14536078 15147722 15241418 15279786 16156666 17055429 17303408 17660363 18590585 18636226 20027199 20713526 2191300 28536364 7575488
CDK2 CDKN2A â—¼   DOWN_REGULATES ✅ - 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
CDK2 BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
CDK2 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 43.0 1.0 Omnipath 8662865 15572662 17717077 26577046 7476977 20116396 24291072 10628747 24333793 11509655 21945472 21447625 29301281 27852068 25252652 22809143 18202149 18088087 15798179 19118566 9171245 10655479 11110801 15601848 28412963 19706513 22697792 12529413 15212693 19904813 24302725
CDK2 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22002055 15985436 12676926
CDK2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 10197981 15241418 19218245 25241761 15520018 20068231 17099224 16156666 16189514 19413330 14512875 12193595 15212693 19114991
CDK2 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 67.0 1.0 Omnipath 32076484 26123729 17081983 27998958 16565220 19007248 19367720 23840880 12058066 19690332 22285574 25922180 21272329 19413330 20333249 24282781 32092641 27553022 19933848 19933706 16083285 18318008 20068231 24998852 23627734 26993766 18165222 17535915 18669648 24290756 17942908 81161106 18691976 11278991 19561638 17287340 16376875 18243139 19651622 17924679 18220336 24282525 19369195 15190079 25531824 18212344
CDK2 RBL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 20857408 17570479 11042701 9188854 11157749 12006580 15212693 10825149
CDK2 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20530684 28396830
CDK2 PTHLH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12504010 10373465
CDK2 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21902831 10942602 25751651 25552934 22179841 17570479 10082583 26825227 10764802 9710583
CDK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 24173284 9315650 19413330 19664995 16083285 1088347 16552184 10884347 17570479 10747897 25241761 7624134 11687964 17287340 92065884 12064478 19556892 14640983 10348343 14702041
CDK2 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21765472 21965652 21907702 18983824 24242917
CDK2 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21602882 18769144
EP300 CDKN2A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
CDKN2A CREBBP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
TWIST1 CDKN2A â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 15640618 17936558 20818389 21383063 21678481 21685941 22796940
BMI1 CDKN2A â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 15640618 17936558 20818389 21383063 21678481 21685941 22796940
TP53 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 16103197 22467867 18555006 8631601 11402335 19649205 22020338 21164364 17265068 16764954 15775976 22056554 18275833 21483786 10348346 19216023 12384561 12091906 19901969 11360201 15205322 11818069 21892281 10980602 11739748 11559812 24672805 10097151 17907153 19244234 15361884 10652576 9436028 21447739 20569441 21555589 21637567 10816133 9774662 19240179
TP73 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12766778 18555006 11870517 18829110 11309270 14733783
TP63 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9151818 19340300 19554267 21093383 19672307 8995628
TWIST1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22796940 20818389 17690110 15640618
NPM1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16957780 20208519 15289458 16199867 16915296
BMI1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 21383063 9308237 21678481 17936558 22796940 20818389 11283613 15640618 19404261 21685941
CDKN2A CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 17881001 26186194 23602568 9751050 11739795 11556834 9380698 15232106 16713569 17955473 10491434 16915296 17909018
CDKN2A CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 37.0 1.0 Omnipath 17145710 11900540 23602568 9529249 11556834 16161044 17881001 17517622 15065884 9228064 15232106 26496610 10585280 17909018 26186194 17353931 10580009 17955473 10491434 12529334 10719365 28042499 8259215 24855949 8891723 23455922
CDKN2A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15856024 15989956 9724636 19960022 12740913 17158541 12640129 19590512
CHEK1 CDC25C â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17384638 17568790 17582221 18677104 19793801 20126263
TP53 CHEK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21546904 11158294 20190799 19435816 18632613 15016801 19395378 11152453 18753293
CHEK1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22084676 18524021 23508805 14585975
CHEK1 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 102.0 1.0 Omnipath 29774099 17145710 10391675 18321553 29425806 10214922 20716119 18677104 20860841 15798197 19793801 11836499 10681541 21152443 12505356 27603133 24505404 11333986 9836640 11551930 17097061 23880065 15736430 26485758 11240139 9889122 20068231 17116885 12742231 28442587 17582221 20126263 14681223 9278511 17384638 15629715 12814430 11313986 11741534 20068082 24079846 26542114 9278512 9659898 15705874 11027648 24525428 9914179 10557092 15459660 10676638 9810229 15150265 10209160 17296725 15296723 25512053 12399544 21035467 9543386 9744884 19490919 28396830 17102137 17568790 16488126 16330544 12478465
CHEK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 20950777 18778462 25545885 18677104 20860841 15798197 19793801 22891162 16511572 23852422 16713569 15865930 11551930 19923893 15467443 11709713 21748595 17116885 15659650 17582221 26384650 10673501 17384638 23966620 23892398 17118344 9765199 15140942 19788416 10801407 18319725 12781359 12897801 25823026 15459660 23296650 15024084 17296725 17102137 11896572 17339337 19933256 20526329 28140789
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
COPS5 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14993265 12374795
DDX5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24219989 15660129 20876186 19626115
DDX5 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15298701 17369852 20022962
LYL1 EP300 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18160048 21486943 15620361 11840323 27128622
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15965232
EP300 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10944526 9001254
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 21988832 23331499 9169454 12237408 10199400 11264182 7878020 8047140 12958365 19171760 11371641 16027720 17074756 17469772 21269274 15623506
EP300 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 11804596 19407812 15175157 19788416 12660246 19218448 10648616 15454570 16998810 25675294 15893728 18663001
EP300 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12419246 14500836 10673036 22298955
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
EP300 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 12408818 10887155 15831498 21269274
GNL3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20664182 12464630 16713569
TP53 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9266967 20094059 15153330 17611664 18945670 14614455 17293853
KAT2B MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 9659901 10944526 10619020
KAT2B SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 34576109 17074756 11058129
KAT2B TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11804596 19407812 19788416 12660246 14614455 18663001
KAT2B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 19680552 11804596 12068014 16537920 9891054 10490106 14614455 20589832 19788416 12660246 12501250 16959611 19407812 9744860 15965232 16678111 17977830 17189186
KAT2B CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9687573 8684459 9687513 9445475 11864601 9267036 17496784
KAT2B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11058129 15994459
XRCC6 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
CTNNB1 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
XRCC5 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
KAT5 TCF7L2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
KAT5 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16603769 16904321
KAT5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17188038 15310756 18280244 16601686
RCOR1 KDM1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 21300290 18806873 24217620 11102443 21258344 20389281 11171972 21142040 21670149 19703393 17537733 21602794 16885027 26226427 12032298 20164337 17218267 16140033 22143567 17687328 16956976 16079794
KDM1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17805299 26334721 19381457
NPM1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 23443559 15144954 16740634 15310764 16376884 12080348
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
PRKDC HNRNPU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27303920 25986610 19351595 25030905 19844162
PRKDC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 15355354 19398950 15254178 9372954 11483158 7862459 16713569 11875057 11551930 11883897 12548019 25168287 8502477 11709713 10446957 28145533 22726545 24886358 16552184 12242661 17570479 10196661 10747897 9885574 10673501 12091386 22355272 9765199 15489221 9561848 10801407 22504299 22444248 15177184 11042698 10358069 10470151 10606744 9744860 16397295 12959929 12064478 27130668 10951572 12111733 25937999 15381073 28102346 9363941 19918261
PRKDC SRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17570479 8407951
RCOR1 REST â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19394292 10449787
SIRT1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21071413 23331499 17098745
SIRT1 XRCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17334224 16189514 15205477
SIRT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18235502 11672523 18235501 15205477 35931247 15989956 17964266 25280219 19047049 16713569 19960022 21245319 12006491 19590512
SMARCA4 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11532957 14964309
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
TP53 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 23665346 23063463 7479001 11470783 20947822
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
TP53 CDC25C â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11396965 16582636 16807237 15574328 19861536 11972334
TP53 SERPINB5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12011991 15578720 17700520 10692390 17204482
TP53 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12732139 10618379 22264233 23706820 14514686 8183578 14761612 16138117 18593586 23063463 8119773
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
E4F1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10644996 16652157 12446718 16713569 17110336
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
TP53BP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25579814 12110597 25837623 16713569 14978302 22653443 26022179 27546791 8016121 12351827 15611139 15364958 14985081 19433796 17805299 25651062 11877378 17634560 22084066 20307547
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
TP53 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18431400 29302370 16753148 16713569 10853038
TP53 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11238924 18431400 21508668 9891077
XRCC5 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
TP73 CDC25C â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19861536 11396965
TP73 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10648616 21245298 11172610 10435630
TWIST1 BMI1 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 11283614 11528470 12490555 13130303 14623871 15140942 15574337 15640618 15980428 16510505 16716598 16831886 17055429 17093497 17332325 17537911 17550342 17936558 17987801 18297062 18832382 19208835 19284610 19336515 20027199 20713526 20731704 20818389 21199805 21317430 21383063 21502402 21678481 21685941 21733352 2191300 21919891 22406545 22796940 22945800 7768934 9278421
TWIST1 BMI1 â—¼   PROTEIN_INTERACTION 42.0 1.0 ACSN 11283614 11528470 12490555 13130303 14623871 15140942 15574337 15640618 15980428 16510505 16716598 16831886 17055429 17093497 17332325 17537911 17550342 17936558 17987801 18297062 18832382 19208835 19284610 19336515 20027199 20713526 20731704 20818389 21199805 21317430 21383063 21502402 21678481 21685941 21733352 2191300 21919891 22406545 22796940 22945800 7768934 9278421
TWIST1 BMI1 â—¼   UP_REGULATES ✅ + 42.0 1.0 ACSN 11283614 11528470 12490555 13130303 14623871 15140942 15574337 15640618 15980428 16510505 16716598 16831886 17055429 17093497 17332325 17537911 17550342 17936558 17987801 18297062 18832382 19208835 19284610 19336515 20027199 20713526 20731704 20818389 21199805 21317430 21383063 21502402 21678481 21685941 21733352 2191300 21919891 22406545 22796940 22945800 7768934 9278421
TWIST1 ZEB1 â—¼   UP_REGULATES ✅ + 37.0 1.0 ACSN 11283614 11528470 12490555 13130303 14623871 15140942 15574337 15640618 15980428 16510505 16716598 16831886 17055429 17093497 17332325 17537911 17550342 17987801 18297062 18832382 19208835 19284610 19336515 20027199 20713526 20731704 20818389 21199805 21317430 21502402 21733352 2191300 21919891 22406545 22945800 7768934 9278421
TWIST1 GJA1 â—¼   UP_REGULATES ✅ + 37.0 1.0 ACSN 11283614 11528470 12490555 13130303 14623871 15140942 15574337 15640618 15980428 16510505 16716598 16831886 17055429 17093497 17332325 17537911 17550342 17987801 18297062 18832382 19208835 19284610 19336515 20027199 20713526 20731704 20818389 21199805 21317430 21502402 21733352 2191300 21919891 22406545 22945800 7768934 9278421
CSNK2A1 TWIST1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21559372
SMAD3 COL1A2 â—¼   UP_REGULATES ✅ + 34.0 1.0 ACSN 10964912 11007770 11013220 11074002 11114293 11279127 11283614 11792802 12545156 12702545 12809600 15001984 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9389648 9618481
SMAD2 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11478938 19397700 9886263 16319104
SMAD7 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14520013 11279127 9886263 19641518 19397700 16126788
SMAD3 COL1A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11074002 9389648 11114293 11013220
CDKN2B CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 26186194 26578655 23602568 25416956 32296183
CCND2 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10477583 17517622 16713569
CDK6 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17208333
CDK6 RBL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 10498883 10385618 9736735 11157749 12006580
PAX7 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18854138 15501225 17548510 18508329
SRF MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17377068 8744946 9658178 23406902
CREBBP MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10944526 16713569 11463815 9238849 2176177
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
CDK4 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21902831 10022835 10601020
SERPINE1 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22449964 2544876 2161846 21199867 3090045 9184208
SMAD3 SMAD7 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD2 SMAD7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD3 SMAD7 â—¼   PROTEIN_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD2 SMAD7 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD3 SMAD7 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
TGFB1 SMAD7 â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 7594497 9157999 9335507
SMAD3 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10823886 15183844 12761881 10887185 10973944 10839991 10753944 10843994 15579469 10559222
SMAD2 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15183844 10887185 10753944 10843994 10559222
SMAD7 CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17657819 19667256 19959709 19397700 20222112
SMAD7 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10887185 15855807 9886263 20631490 22656308 19214138 23633623 14600158 10753944 11912247 11385614 11180003 17928287 19010789 22496417 22841502 17074765 15496141 11448947
SMAD7 ACTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15788410 17475816 20628268 19861282 18065393 18992195
CTNNB1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 15684397 21071413 18988627
TGFB1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19010789 14718519 16474430 17934056 20519943 9335507 21900405 11133108 14557817 15548370 19920116
SMAD7 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 9892009 26555259 9892110
SMAD7 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17438144 21071413 9892009 9892110
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD3 SMAD2 â—¼   PROTEIN_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
TGFB1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
SMAD2 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15198928 23063463 19132220 11879191
SMAD2 ACTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20628268 18631173 18065393 17105765
SMAD2 CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22576977 15883213 19309720 23631855 19397700 11991857
CREBBP SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16751102 18003620 9679056 15750622 17283070 20403362 17074756 15231748
TGFB1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15548370 19010789 10678166 16474430 9311995 23831640 17934056 20519943 24075003 11792802 11133108 21900405 14557817 11278410 19920116 9865696
SMAD6 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9256479 21071413 9892110
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD2 CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9389648 11013220 10454538 9670020 11283613 11074002 11283614
TGFB1 SMAD3 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
TGFB1 SMAD3 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
TGFB1 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
CDK4 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 10197981 12193595 15241418 16156666
SMAD3 GLI2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD3 ZEB1 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 14976548 15265520 16179589 16713975 16831886 18768831 18832382 19208835 19597490 20731704 21042762 21317430 21614932 22331441 8515656 8893010 9389648
SMAD3 PTHLH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24330518 12628005 11473361 11590145
SMAD3 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11278818 11331591
SMAD3 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19643931 15840021 19563779 12551947 24330518 9792626 19132220 19887897 11590145 9765209 19586629 18333754 16169848 15561701 10092624 10557285 20093492 11387330 9606191 17761371 23063463 15198928 9380693
SMAD3 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26553048 27974707 10708950 19214138
SMAD3 CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20222112 21986102 22329991 15987746 19309720 22576977 23249750 11590167 16469114 19570811
SMAD3 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14647420 15326485 23032366 16819512
CREBBP SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15849193 10497242 15467747 18003620 9679056 15990875 15750622 19589780 17074756 17283070 9679060
CDK4 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 34003249 10197981 15241418 25241761 19920136 15520018 20068231 17099224 16156666 16189514 19413330 14512875 12193595 33051597 19114991
TGFB1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21557273 24899689 24075003 24485922 28756206 32196115
SMAD3 CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9389648 11013220 10454538 9670020 11283613 11074002 11283614
ZEB1 LMO2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10048576 11528470 13130303 16556862 16716598 19208835 19839049 20589835 20731704 21081489 21224848 22349261 22439866 225147423 7768934 9278421 9811054
ZEB1 LMO2 â—¼   PROTEIN_INTERACTION 17.0 1.0 ACSN 10048576 11528470 13130303 16556862 16716598 19208835 19839049 20589835 20731704 21081489 21224848 22349261 22439866 225147423 7768934 9278421 9811054
ZEB1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
ZEB1 SOX2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
CTBP1 ZEB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24722188 26186194 12714599 16061479
ZEB2 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24722188 26186194 12714599 12743039 16061479
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 TCF7L2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SERPINB5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18247378 23770133 10709100
CSNK2A1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17287340 19413330 22113938 18669648
HDAC1 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20081843 21234400
CSNK2A1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 19007248 16565220 20166139 17081983 20230923 25609639 19413330 19415658 20388487 20068231 18452278 18669648 18691976 17287340 12176973 19651622 12082111 19691289 24526703 18510355 18212344
KLF8 CTBP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10756197 16713569
CTNNB1 CREBBP â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
CREBBP TCF7L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
CREBBP CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10769018 21751375 11973335 17410209 18347063 16476742 23273993
CREBBP MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8654374 11073948 12196545 16055500 18585056 16799563 23980173 14761981
SUFU GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20463034 10564661 35044719 16316410
MYB CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11287612 8398978 1347906
CDKN2B CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 25910212 23455922 26186194 23602568 7478582 19447967 16169070 31515488 16189514 32296183 26496610 9111314 9042862 9163429 21900206
CCND2 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25910212 17517622 27107012 11896535 10477583 9325318 31515488 16189514 32296183
CDK4 RBL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10498883 10385618 9736735 11157749 12006580
HSPA1A AIFM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11533664 12930708 16713569
SMAD1 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10692396 17215250 22219353 22072987
SMAD6 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9256479 9335505 9436979 21071413 18988627 11483516 12857866
CSNK2A1 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15064744
CSNK2A1 G3BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 27022092 33065005 32302571 32302572 12642610 27083003 23163895 11604510 31171631 27920254
CTNNB1 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
TCF7L2 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
CCND2 RBL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10385618 9736735 12006580 10498883
CSNK2A1 HSPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10772927 12558502
CSNK2A1 SRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 1547771 19778940 1740119 2046671 92191991 18669648
CSNK2A1 SSB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17081983 10715123 16083285 9054510 18257391 15485924 97207017 19039329
CSNK2A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12700239 12432063
CSNK2A1 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11522824 7735324 11313925
CSNK2A1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11711551 18452278
TCF7L2 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24214913 14706452 19347947 24317174
CTNNB1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17145710 9488439 11713475 12446687 17143293 27902311 16569639 22014570 16724116 11955446 16442529 26350900 19202075 17050667 20126258 22056988 16306047 17914096 19443654 18391971 21670201 22155184 10080941 17283121 16230076 22304967 16630820 15684397 11713476 12861022 19304756 20492721 19816403 18772112
SRF ACTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16814806 12450213 19797053 24106278 24802754 18296735 12890560 18496575 9473329 10993896
HSPA1A HSPH1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 8721986 18550409 9873016 7585962 9305631
CTBP1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12711682
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870