Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
YWHAQ MEF2D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214226 11433030
MEF2D MYF6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7739551
MEF2D DES â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25653159
MEF2D MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8798771 9858528
LMO4 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11751867 12925972
VIM NEFL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
NEFL DES â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
NEFL SYNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEFL KRT33B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GFAP PKP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPH PIH1D2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIH1D2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATF2 PABPC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18083832 16129666
C1ORF216 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
C1ORF216 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
C1ORF216 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDH1 EPCAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP63 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22777354 23837456
JPH3 CWF19L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VIM DES â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GFAP DES â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT DES â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JPH3 DES â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MEF2C DES â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8062833 8626009
DES VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32296183 27107012
HTT DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EPCAM DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT DLX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VIM ESRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 ESRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JPH3 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPATA22 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VIM GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GFAP KRT33B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GFAP SYNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
S100A1 GFAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 10510252
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KRT33B HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPATA22 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT KRT20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPATA22 JPH3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KRT20 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PRPH KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TFIP11 KRT20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PRPH KRT33B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MEF2C MYF6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7739551
MYF5 MYF6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17948300 7852366
VIM NEB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TRIM63 NEB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18157088 6492033
OCLN SPTAN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SPATA22 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VIM SYNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZEB1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23160379 17615296
DES KRT33B â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
LAD1 PKP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CDH1 PKP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
C6orf132 PKP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
GSTP1 KRT33B â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
ESRP1 GRHL2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PKP3 ST14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EPCAM PKP3 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PKP3 SPINT1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
LAD1 ST14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EPCAM LAD1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
KRT33B LMO4 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
C1ORF216 KRT33B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
CDH1 ESRP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
BMI1 SAP18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 PTBP3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
MEF2A MEF2C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 33961781
DES PPL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
ESRP1 SPINT1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EPCAM ESRP1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DES POLR2G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
CDH1 EPCAM â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EPCAM ST14 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EPCAM SPINT1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CDC73 POLR2G â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
CRTAP LEPRE1 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
DES LBX1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
SPINT1 ST14 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
DES KRT37 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
CDH1 SPINT1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
SPINT1 ST14 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
ESRP1 ST14 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
DES NEFH â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
DDX6 DES â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CDH1 ST14 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
DES LMO4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
BRCA1 MLH1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
DES KRT75 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
DES NEFL â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PML RNF4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
C1ORF216 DES â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CRYAB HSPB1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
KRT20 VIM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT75 LMO4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
DES PRPH â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
DES LENG1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
MEF2D MEF2A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 8798771 25609649 9858528 20590529
RNF4 PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18708055 29180619 24907272 19380586 18408734 15707587 21252943 22388745 24637324 23028697
C1ORF216 KRT75 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
DES KRT20 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRT75 VIM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
DES YES1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
NEFH PRPH â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
DES VIM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
LMO4 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11751867 12925972 16713569
MLH1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16786532 29656893 21240188 17148452 25184681 10783165
MYF6 DES â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8382796 8062833
MYF5 DES â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8382796 8062833
ZEB1 GRHL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23943797 23814079
LBX1 ZEB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19651985 23943797
MYOD1 MEF2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11948187 14550531 7852366
MEF2A MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11948187 16318624 17377068
MEF2A MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8548800 9418854
VIM PRPH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NEFH VIM â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
LMO4 MYOD1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT33B KRT75 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT37 KRT75 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT20 KRT75 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CRTAP LEPRE1 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
DES VIM â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
HSPB1 MAPKAPK2 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
PRPH VIM â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
HSPB1 CRYAB â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 23532854 12601044 20863832 1560006 28919577 26186194 17916631 28514442 11700327 18330356 23188086
NEFL NEFM â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
YWHAQ MEF2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11433030 23331499
LMO4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11751867 16713569 12925972
AURKB VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 14762106 14722118 11895474 17081983 19007248 11420699 15676024 12458200 18669648
AURKB GFAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9099667 7822264 11940606 12177195 2155236 8647894 2114109 12686604
AURKB DES â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15630414 10574968 12686604
ZEB1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
ZEB1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 17997862 16424029 17615296 23890107 23160379 19435871 18411277 23667256 20139075 12508111 12714599 23518002 20207041 16862183 22249256 18321996 18805502 19706487 19839049 22147512 23743934 15674322 19921427 16804902 20332115 10949939 21771732 18487993 17655524 15311212 12161443 21593765
ZEB1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 15169839 9389648 17615296 22796940 19839049 20818389 21224848 20519943 21685935 12508111 11309385 11074002 225147423 19597490 12743038 14673164
MYOD1 DES â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17950683 9497371 8382796 8062833 9502427 8276797 25653159
MYOG DES â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8382796 8062833 9502427 8276797 25653159
ROCK1 DES â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10574968 12686604
PKP2 DSP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25225338 11790773 22781308
ROCK1 GFAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 9099667 7822264 12177195 2155236 2114109 15212693 12686604
MAPKAPK2 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 150.0 1.0 Omnipath 17081983 16565220 11839738 19562805 19166925 19415658 32570757 25257914 20626350 17170118 26887051 11042204 11383510 25241761 21575178 24421331 14499342 19651622 19691289 17924679 25728673 20044836 21423207 18707149 16964243 19007248 15581903 17576778 12096113 11844797 8774846 18669648 12829704 12740362 12377770 18691976 15682460 16840785 8995385 18477563 14612593 19369195 10978313 18720982 18212344 17697330 1332886 18767875 18326031 18187866 19664995 15302935 21245386 15850461 14717697 20068231 25675293 93076920 1730670 21357508 18088087 7799959 10383393 20886841 23950959 12367505 29330367 28460458 20166139 15728188 20230923 21989268 19413330 16840786 14688255 18578522 25048900 15976317 21131586 23112078 18950704 20058876 19597476 16097034 19664994 11274345
MAPKAPK2 KRT20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20724476 16608857
MAPKAPK2 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11895474 17081983 16565220 10852918 2500966 15713670 15766329 7983050 12761892 16964243 9794428 15345747 16140754
MEF2A MYF6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9056635 7852366 7739551
MEF2C MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15743821 9418854
ROCK1 MSN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 8522586 9856983 9287351 10970850 12778124 12045227 15634677 9516463 12802084 7579708 10047517 8527459
MYF5 MYOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11784084 1315706 14724123 1341049 10548518
MYF5 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15367664 20978076 14724123 12500905 10101129 14732408
MYOG MYF6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9056635 9186058 7852366 7739551
MYF6 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20978076 12500905 7852366 2560751
MYOD1 MYOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 21543328 16901893 18676376 12782625 17940050 1581290 12578986 12694204 15870273 1718977 17562853 21892963 22773876 15149596 16858404 20026657 10548518 20466877 11279181 24550007 22710712 17932502 2560751 7852366 11784084 19723804 8119948 15798192 16847330 12101422
RNF4 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23028697 18708055 15707587 24907272 18408734 21252943 22388745 24637324 19380586
ROCK1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 14722118 11895474 19007248 17081983 20166139 9565595 11420699 20068231 12458200 18669648