Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GMCL1 NTAQ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
NTAQ1 RBBP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NTAQ1 TRIP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NTAQ1 THAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
ACTB HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APEX1 ACTB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16431169 11082319
CREB1 APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20573957 17938202
SP1 APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18208837 7534297
TDG APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11864601
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
AR PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 20610535
TDG AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129768
AR NKX3-1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8943214
RHOXF2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL12 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SQSTM1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
NR4A1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
UBE2V1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2E3 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TRAF2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ZC3H10 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TRIM38 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 ZC3H10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
FUS BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18471544
ESR1 BLM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17268063
BTBD1 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
C18ORF25 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ESR1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20404154 17932106
TRAF2 CDKN1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MYC CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24704206 26701207
HTT CREB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CREB1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10775268
CREB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
MECP2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
UBC DAXX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218776 16810318
DAXX HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DAXX TRIM54 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
HTT DDX39A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TDG DDX39B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14667819 5216829
HTT DES â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 TRPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23031797 18414489
NCOA1 ESR1 â—¼   PROXIMITY 2.0 0.8 intact 5222291 17627277
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
ESR1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24641954 20623181
FADD IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16227629 23131831
FAM9A TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FAM9A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FAM9A TRIM54 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
TARDBP FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TBP FUS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19841068
UBE2I GMCL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GMCL1 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
UBQLN1 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HGS UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HNF4A TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19805548
TARDBP HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TARDBP HNRNPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HNRNPH1 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KLHL12 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2H HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MECP2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LCE1B HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TFG HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT UBA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14651848 16906147
PARP1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRIM28 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC IKBKG â—¼   COLOCALIZATION 2.0 0.8 intact 20970423 8045055
SQSTM1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16874300
SUMO1 MDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
UBE2I MDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SP1 MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18173747
MECP2 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TARDBP MYC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC NFYA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11282029
NFATC2IP RNF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17762865 6169000
NFYC NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12857858 22969033
PARP1 NMNAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0609211104 17360427
SP1 NR4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8961265
RPS6KA2 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11883936
PARP1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
PARP1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PARP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
SUMO1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19622798
PATZ1 RNF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11719514 10713105
PIAS1 PGR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17053081 0603002103
PGR SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14500579 16175636
TDG PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129768
UBE2I PHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PIAS1 SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PRMT5 TRIM54 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
TRPS1 RNF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12885770 5216574
RNF4 SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF4 TRPS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12885770
RPA1 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24782567 20705237
RPA1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24782567 20705237
UBE2I SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TDG SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TOP2A SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18394993 25114211
TDG SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218717 16763556
UBE2N SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
UBE2V1 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I TOP2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12832072 10862613
TRAF4 UBA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18082607
UBE2E3 TRIM54 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
UBE2I TRIM54 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
TRIP13 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
UBE2I TRPS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17391059 23772552
UBC UBE2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 5211616 10388568
UBE2A UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2N UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
ZCCHC17 UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBC9 TIF1B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 18082607 21940674 31427381 18488044 24018422 26055329
SUMO1 TIF1B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24654937 18082607 21642969 21098080 19596686
HNF4A SP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 15651981 16713569 19115260
SUMO2 MDC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 32786267 19471022 22661230 19394292
UBC SQSTM1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5216530 12857745
UBE2N UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ARID3C C14ORF119 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
TRAF2 TRAF3 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
HIST2H3C UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
FAM9A PRR20D â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
FAM9A LCE1E â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
DNMT1 UBC â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
UBE2D3 UHRF1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
RNF4 HNRPK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 29180619
MYC HNRPK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
SUMO1 ANDR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12177000 21242980
NFYA UB2D2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
APEX1 HNRPC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28986522 34079125
RNF4 B2CL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 29180619
BTBD1 NTAQ1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32296183
NTAQ1 TRAF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RNF4 ZN696 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 29180619
RNF4 ZN275 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 29180619
RNF4 ZN319 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 29180619
ESR1 APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
APEX1 DNMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28986522 34079125
MECP2 BLM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BLM PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24239288 34079125
RNF4 DAXX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 29695423
MYC DNMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
SP1 MECP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15109260 20385708
MYC UBA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC TDG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 26496610
MYC TOP2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
PARP1 TOP2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16794079 34079125
RNF4 STX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 29180619
ESR1 PGR â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
HIST2H3C UBC â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
LCE1D LCE2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
RNF4 UBE2N â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
LCE1B LCE2D â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
HNRPK UBC9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22825850 32296183 16189514 16713569
TRPS1 UBC9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23772552 17391059
UBC9 RNF4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19549727 20936779 32296183 29180619
SUMO1 HNRPC â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24654937 25416956 32296183 21110914
RNF4 HNRPC â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32521226 32296183 29180619
THAP1 NTAQ1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 8153045 21516116
RNF4 ACTB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32521226 32296183 29180619
ESR1 SRPK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 31527615 21182205
TRPS1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23772552 17391059
UBE2A UBE2B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 25582440
HNF4A NCOA1 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
UBA1 UBE2E2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PARP1 UBE2I â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
UBC9 ATF2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9488727 16713569
UBC9 TRAF3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24260396 32296183
MYC ACTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29467282 11839798
SUMO2 BLM â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19471022 16524884 16620772 21693764
ESR1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15961505 31527615
ESR1 NCOA1 â—¼   PROXIMITY ✅ 0.84 0.84 mint 17627277 5222291
UBC HGS â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 12750381 5216384
HGS UBA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19019082 25260751
HNF4A SUMO2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 35140242 22505616
TRAF2 TAB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19150425 17384642 14633987 10882101
TAB3 TRAF2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 14633987 16713569
HTT SQSTM1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
LCE2B LCE2D â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
RNF4 UBE2D3 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
TRAF2 TRAIP â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
PARP1 UHRF1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31964471 24782312 34079125
UHRF1 UB2D3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 30392931 27595565 26299963
SUMO1 HNRPK â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15161980 23092970 19596686
PIAS1 ANDR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11117529 31752909 25552417 11877418 12177000
ANDR TCF20 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33640491 21935435 28611094
TOP2B UBC9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15561718 10862613
RNF4 TIF1B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24907272 29180619 21252943
UB2D1 RNF4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24714598 23504328 27678051 18408734 23560854 26950370 19549727 24969970 33188014 24882209 32733036 19690564 21857666 24656128
FANCA BLM â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22705371 12973351 23509288 22343915 12724401
BLM MYC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 30415952 29467282 23750012
FADD MYD88 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10880445 16189514 11828002 21988832
NCOA1 TBP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8754792 16713569
SUMO2 PARP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19471022 25027693 32786267 19779455 21252943 21693764
TBP RNF4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11696545 9710597
TRAF5 TRAF2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 32296183 9718306 21903422
LCE1F LCE2D â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
TAB2 TRAF2 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
LXN TRAIP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
UBA1 UBE2D4 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
UBC UBQLN2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
LCE1B LCE1F â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
PARP1 UBC9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15561718 23871147 9197546 19596686
RNF4 UB2D2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23530056 31048496 25960396 27678051 23560854 19549727 19690564 31087003
UB2D3 RNF4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23530056 27678051 23560854 19549727 33723063 32360601 19690564
MYC TBP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15723054 16713569 8755740
SUMO1 PARP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19779455 15561718 23871147 15576338 19596686
PARP1 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20085707 34079125
RNF4 SP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10617653 21983342 26511642 34550526
SUMO2 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19471022 25027693 19394292 18381449 32786267 21252943 20797634 21693764
SUMO2 TOP2B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19471022 25027693 19394292 21252943 21693764
LCE1B LCE2B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
MDC1 UBE2E2 â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
DAXX DNMT1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
UBA1 UBE2W â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
TOP1 HNRPC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15848144 22939629
SRPK2 HNRPC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23602568 26167880
MYC TIF1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 17353931
RNF4 UB2E1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19549727 30282802 25960396
ESR1 ACTB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20308691 19805454 21182205 21182203 31527615 20348541
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PIAS1 ESR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31527615 11117529 15666801
ESR1 TRPS1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23403292 31527615 26153859
MYC UBC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 16996503 19131971
MYC TOP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 17314511 29467282 20195357
SUMO2 PML â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25027693 21148299 23543742 17000644 20797634 22155184 21779164 19553342 9452416 17081986 16713569 24637324 21693764 19471022 21252943 15940266 16189514 22578841 20826694 24190887 28851805
TAB3 TAB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 14633987 34012913 21903422
LCE1B LCE5A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
LCE1F LCE5A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
LCE2B LCE5A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
DAXX UBE2I â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PRR20D ZC3H10 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
MAP3K7 TRAF2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TRAF3 TRAF5 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
UCHL1 UBC â—¼   CLEAVAGE ✅ + 0.87 0.87 Signor 9521656
RNF4 UBE2D2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
DDX39A DDX39B â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
PIAS1 SUMO2 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
SP1 ANDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15661808 10809237 9535906 17984071 23369005
UBC9 ANDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19692572 8798622 10383460
UBC9 TOP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10759568 16713569
CFL2 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8153045 21516116
BTBD1 TOP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11818025 21092135
DNMT1 PARP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27728808 23708667 34079125
NCOA1 NR4A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12082103 16713569 16002533
TBP NFYB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9153318 16713569
PML RNF4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
TCF20 RNF4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10849425 29180619
SP1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18239466 18572193
TAB3 UBC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
UBA1 UBE2A â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
LCE1F LCE2B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
RNF4 UBE2D1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
PIAS1 UBC9 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12356736 11867732 22661230 14609633 19965618 19692572 11583632 20936779 15561718 30217970 12177000 16713569 25557546 16148010
UBC9 PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30935967 32001251 12641448 9885291 15809060 29535160 17081986 27030546 29773808 27903803 15561718 18691969 30292834 21988832 29599493 22155184
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
SUMO2 DAXX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22578841 19471022 19394292 32786267 16475184 17081986 21252943 21693764 28851805 21383010
TBP ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11595744 31527615 16713569 9259327
TDG ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12874288 16282588
NFYC MYC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10446203 11282029
MYC PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17146439 21150319 32592588 30415952 15735755
NR4A1 PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12032831 16713569 16189514
PATZ1 RNF4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10713105 11719514
RNF4 PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18708055 29180619 24907272 19380586 18408734 15707587 21252943 22388745 24637324 23028697
UBC UBE2D3 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
DAXX SUMO2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
TRAF2 UBE2N â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RHOXF2 VENTX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
UBA1 UBE2D3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NCOA1 PGR â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
AR NCOA1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
ZBTB26 ZBTB34 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
UBC UCHL5 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
UHRF1 DNMT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22064703 21268065 26065575 33170271 28803780 19800870 31322780 29691401 27045799 33465813 24782312 27049577 20613874 24368767 21045206 17934516 19943104 21745816 17673620 29268763 19798101
NCOA1 ANDR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10567563 12163482 23975195 33640491 15256534 12612084 10731636 16713569 17353003
ANDR DAXX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27671201 15350595 32694250 15572661
UBC9 DAXX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12150977 21474068 11112409 17081986 18691969 16713569 23395904 15087395
MYC HNRPC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21150319 30415952 29467282 17353931
ACTB BCL2L1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NFYA ACTB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1762920
NFYB ACTB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1762920
APEX1 TDG â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11889051 15823533 18805789
AR PIAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 18656483 10628744
AR TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 9238003
AR CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 17522055 18687691
AR BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21310825 20610535 18196538
AR SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24119295 21796528 17932034
SP1 ATF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2145272 12760745
UBE2E1 ATXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18439907 25641559
CREB1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11450946 16205321 18830594
BLM TERF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12181313 19329795 15229185
ESR1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17163418 17681750
CTNNB1 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 21362399 21986938
CTNNB1 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12944908 25241761
NCOA1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9259327 10409727 23874500 11014206 15604093 12554772 16282588 9427757 11113179 18451880 9121466 10598586 16713569 11165056 14715875 11376110 9774463 10760302 20608937 9192892 11003650 26487511 11867769 10454579 12574227 17363140 9773983 10731636 11358671 11250900 11682626 23975195 17627277 16606617 12630920 12714702 9192902 12738788 16957778 15140878
MECP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21655924 23242655 15870696
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
TDG ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12874288 17129768
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
TAB2 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21988832 23986494 17626013
PARP1 KDM5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20832725 33859667
ZNF746 MAP3K7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UBE2N MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17965022 17079228 10702308
MYC SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
NFYB NFYA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14681455 15243141 15831478 32296183 26344197 12857729 26496610 17098936 23332751 16959611 8051128 25416956
SUMO2 NR5A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15192092 15192080 21467194
SUMO1 NR5A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15192092 15192080 21467194
UBE2I NR5A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15192092 15192080 21467194
TOP1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15247263 15848144 34079125
PGR SUMO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19211567 17717077 17020914
PGR UBE2I â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19211567 17717077 17020914
SUMO2 PIAS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22578841 19471022 19394292 20016603 16524884 21252943 18806873 19217413 21693764
SUMO1 PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15017387 15561718 28851805 16501610 19217413 22155184 22875967 24654937 31879127 21779164 20188669 9885291 9452416 17081986 21098080 22406621 18625722 21305000 17344210 17027752 11160742 19380586 23604351 23830076 17081985 9427741 11080164 16189514 23028697 21057547 19015637 20972456 8806687 20826694 24190887 25497731 17036045 11948183 9756909 18474224
TDG PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15569683 16189514 17060459
SP1 PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24728382 21360626 16713569 9819401
PML UBE2I â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
RPA1 RBBP8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
SUMO1 RNF4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24844634 23086935 29180619 32296183 15707587 24151981 24907272
RNF4 SUMO1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SP1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22412893 23995788
TRAIP TRAF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25716317 17544371 30127245 16713569 9104814
UBE2N TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18981220 14713952
UBE2N UBE2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
ZBTB26 ZBTB6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
MDC1 BCL2L1 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
TOP1 TOP2B â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ACTB CFL2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
PRR20D VENTX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
UBE2N UBA1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 27173435 14517261 29537486 18678647 30097011 27182664 25527291 33619271 31638574
UBA1 UBE2E1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
PIAS1 SUMO1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PRR20D RHOXF2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
TOP1 TOP2A â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
UBA1 UBE2N â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
RNF4 SUMO2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
DESI1 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
LCE1D LCE2D â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
LCE1E LCE2B â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
LCE1E LCE5A â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
HNRNPCL1 HNRNPCL2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
DAXX PML â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
SQSTM1 UBC â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
SP1 NFYA â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 10446910 10393239 30392062 15647279
IKBKG UBC â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
LCE1B LCE1E â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
LCE1F LCE3B â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
UBA1 UBE2B â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
LCE1B LCE2C â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
SUMO1 TOP1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 24654937 11709553 12439742 15576338 12149243 19596686
TOP2B TOP2A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 22939629 8710863
LCE1D LCE1F â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
UBA1 UBE2D1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
LCE2B LCE2C â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
UBA1 UBE2D2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
LCE1B LCE1D â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
LCE1B LCE3B â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
SUMO2 TDG â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
TDG UHRF1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
LCE1D LCE2C â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
LCE1E LCE1F â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
LCE1E LCE3B â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
LCE1F LCE2C â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
LCE2C LCE5A â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
UBC UBQLN1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
LCE1D LCE1E â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
LCE1D LCE3B â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
LCE1E LCE2C â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
LCE2C LCE3B â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
RNF4 ANDR â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10617653 16713569 11719514 9710597
UBC9 SUMO2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 25027693 26496610 23871147 24969970 20797634 26344197 30574775 16524884 17938407 16713569 31056421 21693764 19471022 30201799 32786267 12924945 28514442 16189514 21949651 17491593 16620772 22578841 11451954 28784659
SUMO1 TOP2A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 12832072 10862613 19596686 18381449
HGS UBC â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PIAS1 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
UBC UBE2D1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
SUMO1 DAXX â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22578841 31879127 12150977 18583933 20972456 21816224 21474068 11112409 16475184 17081986 30958586 20927612 25409927 19465479 11948183 28851805 23395904 21383010
NFYC NFYA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14681455 33961781 35140242 15243141 32296183 26344197 12857729 23332751 20936779 26186194 28514442
NFYC NFYB â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 35140242 32296183 26344197 26496610 12401788 20936779 21988832 28514442 9388234
SUMO1 TOP2B â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15161980 21110914 10862613 15561718 19596686
SUMO1 TDG â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
UBC UBE2D2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
PML SUMO1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
BLM RPA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
DAXX SUMO1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
TAB2 UBC â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
UBC UCHL1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ESR1 NCOA1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
UBA1 UBC â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
UBC9 SUMO1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 16494873 16732283 18359863 25502805 10961991 26496610 23871147 26264872 15931224 26344197 9497385 16524884 17938407 9920803 18691969 16713569 9353268 11735126 19684601 21518904 32296183 17353931 8921390 17956732 14673145 19785004 21212807 12924945 22411991 20501649 25416956 16189514 17491593 21949651 21174150 24352468 18264111 18211895
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SUMO2 UBE2I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DNMT1 UHRF1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
MAP3K7 TAB2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NFYA NFYC â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NFYA NFYB â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NFYB NFYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
UBC UBE2N â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
UHRF1 TOP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10646863 12530060
UHRF1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19798101 22064703 20210320 17673620 24368767 19800870 27049577 20613874 21268065 24782312 26065575 17934516 21045206 21745816 19308066 27045799
PARP1 APEX1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 17548475 11440997 12727891 15135726 10364231 11340072 9804757
RPA1 APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
MYC APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14519204 11983916 12695333 11085504
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
NKX3-1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18360715 20363913 23492366 17202838 16697957
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
NCOA1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15514032 12163482 23145053 11673464
NFE2L2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24466341 17640564 18588981 15655294 22951256
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
AR TRPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535 15613454
AR UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17409431 20610535 17721441
AR UBE2D3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
UBE2I AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
DAXX AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 27671201 17145710 15350595 15572661
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
AR NR5A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 11518799
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
AR UBE2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
NKX3-1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22869582 19439449 23677993 21354697 11450946 16316993 16214938
MYC BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14517295 18802399 16316993 17331788
BLM FANCA â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCA â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM TERF2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 23253856 24089143 24095737
TERF2 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 15229185 19329795 12181313
MYD88 CCL2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
SP1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10792620 10644332 17255531 8630731 10636866 16847329 10657660 23349788 12787135 12488502 12682245 25108845 8051410
SP1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9349726 12907235 18355800 10072762 19145069 21131823 22415074 15064717 15951157 16105842 23184467 15899840 12773549 12907249 10542271 16518840 11231912 19433067
CREB1 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11160957 11698596 12842905 9770464
RPS6KA2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 9829964 11698596 11018520 11160957 11969286 12235136 7958915 9687510 11909979 8688081
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
FADD DAXX â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866
TRAF2 DAXX â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
FADD DAXX â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866
TRAF2 DAXX â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
FADD DAXX â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866
SQSTM1 DAXX â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 12702723 15340068 16252010 16498403 20531300 21981924 23069999 25002027 26587781 28574505 9184224
DNMT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21655924 20946668 17172825 15746193 22975348 12789259 19001520 24058781 23242655 22558281
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 ESRRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12960079 18174157 20211987
ESR1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 12829318 12554765 12446585 11000528 15019994 8043503 23027806 9058379 9717846 18414489 12706304 10835496 16293641 18784357 12761896 8145766 22543272 15743834 8530508 10894148
PIAS1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15666801 11117529
PGR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 22396492 16168121 12612073 11000528 18988627 26153859
NCOA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 18451880 9192892 16957778 11014206 16713569 17627277 23975195 15140878 15604093 12738788 17363140 11003650 10454579 16606617 26487511 11165056 10760302 10731636 12630920 14715875 9773983 9427757 9121466 20608937 12714702 9259327 9192902 11358671 10598586 12574227 11113179 12554772 11682626 9774463
TRAF2 FADD â—¼   PHYSICAL_INTERACTION 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
TRAF2 FADD â—¼   SHARES_COMPLEX 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
TRAF2 FADD â—¼   ENZYMATIC_REACTION ✅ 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
SQSTM1 FADD â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 12702723 15340068 16252010 16498403 20531300 21981924 23069999 25002027 26587781 28574505 9184224
FADD IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
FADD MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
FADD TAB3 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
FADD TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
MYD88 FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21988832 10880445 17785432 16189514 11828002
FADD MYD88 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21988832 10880445 17785432 16189514 11828002
SP1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19540905 15651981 23307400
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
TAB2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TRAF2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
MAP3K7 IKBKG â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TAB3 IKBKG â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TRAF2 IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
MAP3K7 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 24911653 11477091 17301840 18180283 19909372 15125833 24699077 17363905 16356855 18641653 24403530 18079694 18223652 14514672 17496917 19531477 20300203 11325957 21133840 21232017 18264787 9744859 10391247 16799562 15836773 10702308 23109003 12620219 14633987 17363973 19161412 22941947 23681101 17047224 29145629 11280761 16301747 15082531 26192618 14660645 20038579 24958845 15327770 20164171 11460167 16603398 21041997
TAB2 MAP3K7 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
MAP3K7 TAB3 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TAB2 MAP3K7 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
MAP3K7 TAB3 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TRAF2 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 12547194 20038579 14633987 14743216 17384642
TAB3 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 21903422 14633987 14743216 17158449 17384642 14670075 22081109
TAB2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 112.0 1.0 Omnipath 17145710 11477091 17301840 18180283 10838074 24912525 16251197 10882101 19556242 15125833 19955178 31250519 36130827 17363905 17158449 11259596 19026643 24699077 14670075 18641653 24061540 24403530 23331499 22158122 12372426 21903422 27426733 21071413 23180781 14743216 18021073 21133840 20200282 26432169 21232017 18264787 20194509 10391247 18988627 22081109 8638164 16799562 11809792 19232515 12620219 14633987 19161412 20538596 22941947 23681101 20932475 15590691 12609980 16845370 27468689 12242293 11280761 15082531 26192618 14660645 24958845 17172402 15327770 25642820 22167179 20164171 16603398 17384642 11460167 21041997
PGR MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8701093 9408078 22396492 9305935 22892083 10651641
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
TBP MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20886042 7880838 9797456 15876353 14506152
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
MYC PAICS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333
MYC NFYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11282029 10446203
NCOA1 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12529333 7481822 10757795 19706513 21273440 16352595 16728408 10722692
NFE2L2 SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23382044 19762340 17189831 20452972 24416372
SP1 NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19564345 12153142 10748033 16442295 23160377 12502798 10542271 9516473 22154511 12697323
NFYA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10393239 12427542 10446910
SP1 NFYB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18654640 9748295 9604010 18559965
SP1 NFYC â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18654640 9748295 9604010 18559965
PARP1 RBBP8 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
SP1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9428683 9493965 17003407 17961220 11278663 12657578 15777284
PARP1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 20875401 15911331 15848144 14699148 15247263
PATZ1 RNF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11719514 10713105
SP1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12554796 12706304 15019994 20087433 10894148
PIAS1 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16524884 22578841 19217413 18806873 14609633 11583632
SUMO1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22875967 9756909 25497731 17036045 21057547 18931695 19217413 8806687 16189514 17081985 11080164 11948183 9885291 19380586 17344210
RNF4 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23028697 18708055 15707587 24907272 18408734 21252943 22388745 24637324 19380586
RPA1 UBE2B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
SP1 SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9762895 12736330 17012241
SP1 UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19733223 17409431 11872750
TOP1 SUMO1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12149243 11709553 25114211 10759568
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
SUMO1 TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 16763556 15959518 17060459 21284855 20504299 16189514 16524884 11889051 10961991
TOP2A SUMO2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24782567 17183683 18381449 25114211
TAB2 TAB3 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TAB2 TAB3 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TRAF2 TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TAB3 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 34012913 14633987 21903422
TRAF2 TAB3 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
UBE2I TDG â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15823533 18691969 21284855 15959518 11889051
UBE2I TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18512959 24753249 18691969
UBE2I TRIM28 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17942393 17079232 25114211 18488044 17298944 18082607
UCHL1 UBC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23801757 22284438 20622874 16169070 20439756 9521656 2532544 27066941
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215
MDC1 TERF2 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368