Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
PIAS1 SUMO1P1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
UBE2I SATB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SATB1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000296 20126258
CHD3 XRCC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16478998
H2BC21 ZMYM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 PPARGC1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PIAS4 ZHX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ZHX1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ZHX1 CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ZHX1 WDR33 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HNRNPC FSBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KAT5 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10364196 5211544
NCOA2 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12588987 5216126
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
MYB AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12096342 18945670
AR RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12069693 20610535
AR TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21303954 20610535
AR RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24119295 20610535
RXRA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15650026
AR RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15650026
AR CASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16007156
HIF1A ARC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22475487 24344197
ARID5B PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17962384 19913508
HIPK3 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ARRB2 MDM2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5214648 11588219
SMAD4 ATF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10480932 23331499
MAPK8 ATF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25301550 26538579
RHOXF2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAD54L2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
CENPV ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TRAF2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 CDK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN3 TDP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN3 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GOLGA2 BCL6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
BCL6 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TP53 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16249378
BCL6 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15577913
BLM PLK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16864798 0601828103
CREB1 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9926942 6548521
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
PIAS4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21113239
BRCA1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15574597
C18ORF25 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CANX TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAPN2 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VHL CARD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17936701
TP53 CASP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21859926 16177095
CASP2 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15590671
PPARA CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
CDH1 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDH1 PRAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP63 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22777354 23837456
MITF CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1999537 11818451
DNMT3A CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16887905 18974268
TP73 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11309270 22842668
CDKN2A CDK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
NR3C1 CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9154817
CREB1 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
PPARA CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16239970 18818403
CDKN2A KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16915296
CENPV SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CENPV KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KPNB1 CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
CHD3 CREB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHD3 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
CREB1 PKM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20577053 16308421
SMAD4 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9689110
CREB1 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
CREB1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10775268
NCOA2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12588987 5216126
XPO1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19940019 18573912
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
CTNNB1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 VHL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16983094 0606850103
RARA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10607566 23331499
CTNNB1 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17000761 15729346
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
HIF1A CYGB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15178412 19203999
TP53 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
DNMT3B DNMT3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20426865 15362956
UBE2I DNMT3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18762900 11735126
DTX2 RHOXF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EPAS1 EGLN3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20061373 15156561
EGLN3 HIF1A â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 5217229 15474027
NPM1 EIF2AK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219054 16957780
TP53 EIF2AK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19416861 10082513
NPM1 EIF2AK2 â—¼   COLOCALIZATION 2.0 0.8 intact 5219054 16957780
NPM1 EIF2AK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12882984 16957780
ING2 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218757 16782091
TCF4 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219834 17410209
EP300 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
HIPK2 EP300 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16917507 5218981
TP73 EP300 â—¼   ACETYLATION ✅ 2.0 0.8 intact 11804596 5215037
FAM120C TFCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PPARG FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20416398 15644454
TP73 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19788416
TP63 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15944736
TP53 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9841917
FOXM1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23635401 18345025
GATA4 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18974883 24204964
TRAF4 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TRAF5 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TDP2 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GOLGA2 TDP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
NPM1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219698 17318229
SMAD4 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
ZBTB16 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
PPARG HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21151932 16431920
ING2 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20574448
MITF HERC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22234890
HGS UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VHL HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
THRB HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16862226 18239067
HIF1A MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12606552 15385570
HIF1A PPP1R10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020
HIF1A PKM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020
HIF1A NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15699159
HIF1A PKM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15379897 8089148
TP53 HIPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217735 15896780
HIPK2 SUMO1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 5217735 15896780
MDM2 HIPK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16212962 5217983
HIPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10961991 23602568
UBE2I HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HNRNPC TCF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 HNRNPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18296503 21317560
TRAF2 IFIH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
ING2 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20621832 7894216
ING2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16782091
UIMC1 INO80B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBE2I KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUMO1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
TFAP2B KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 TCF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 SOX10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 ZMYM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIAS4 KPNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
MAPK1IP1L UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UBE2I MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12393906 20972456
SUMO1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12393906 11384992
UIMC1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19433585
MTOR TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYB PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9371644 7838532
RXRA NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17673910 5223765
NCOA1 NRIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10612426 23547260
NCOA1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16186500 14551261
PPARG NCOR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17011499 8970730
PGR NCOR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17347654 5219745
NCOR2 NRIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9556573 10612426
ZCCHC7 NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UBC NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6541703 18259216
NPM1 SYT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NR1H4 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21279417 15973435
TP53 NR2C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10811662 8663350
NR3C1 RXRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10860926 12573484
RXRA NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12573484 23331499
TRIM28 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9742105
NR3C1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12573484 23331499
NR3C2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20438710 18036328
NR3C2 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15044365 16960100
RXRA NRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11790787 17684114
NRIP1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NRIP1 RORA â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SUMO1 NRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18211901
NUP153 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12917407 23331499
PIAS1 PGR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17053081 0603002103
PGR SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14500579 16175636
SMAD4 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SNCA PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIAS1 PPARG â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16127449 20711444
UBE2I PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
PLAGL1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22001409 11360197
PLK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 7266226 19833129
PPARA RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPARA PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17275789 22033933
THRB PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16260719
PPARG PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18309368
SUMO1 PSIP1 â—¼   COLOCALIZATION 2.0 0.8 intact 8384636 22748127
UBE2A RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAN SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO1 RANGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
UBE3A RARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
UBE2I RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RNF168 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO1 RORA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19041634
RPS3 TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
THRB RXRA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220566 7746322
SAE1 TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 15327968 5217177
SMAD4 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8308197 22045334
TP53 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11420669 21187340
SUMO1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19788416
SUMO1 UIMC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17698038
TP63 TCF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22232078
TDP2 UBC â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TDP2 UBB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TFAP2B TFAP2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2010091 1998122
UBE2I TFCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
THRA THRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1782215 17761769
UBB TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53 WDR33 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ZBTB16 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24821728 24821727
TP53 TRAF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12788948 16969126
XPO1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17268548 17891139
TP53 TRAF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12788948
YAP1 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213829 11278685
TP73 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19815500 0905867106
UBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 ZBTB16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRAF4 UBA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18082607
UBE2I TRPS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17391059 23772552
ZBED1 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ZNF451 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UBE2I XPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17693435 16030353
ZBTB16 WDR33 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RAN UBE2I â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
UBE2I ZNF451 â—¼   PHYSICAL_INTERACTION 809.0 0.8 STRING 36370105
SUMO1 CBX4 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24654937 33961781 20098713 22467880
MDM2 CDKN2A â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 7989562 20713054
PIAS4 VHL â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20300531 24002598 20844582
TP53 UBE2A â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
DNMT1 UBC â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
PLK1 BUB1B â—¼   PHOSPHORYLATION ✅ + 0.81 0.81 Signor 23079597
MUL1 TP53 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
DNMT3A DNMT3B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
HGS ARRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23208550 20505072
DNMT1 CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12867029 17470536
HDAC6 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15102857 19344692 12718889 22778253 23133622
EPAS1 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23275444 22807441 15261140 25689462
EPAS1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20026589 20661221
YAP1 FAS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24366813 31501420
RWDD3 HIF1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25500545 17956732
IFIH1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21156324 33727702
SUMO1 MITF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22012259 16189514 16029420 10694430
PPARG RARA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 32929351
SOX2 SUMO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25416956 17097055
SUMO1 ZBTB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24654937 32296183
UBB UBE3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25416956 22645313
UBB ZRANB1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
TNFRSF1A TRAF2 â—¼   UP_REGULATES ✅ + 0.82 0.82 Signor 10795740
UBB UBE2L6 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
UBC UBE2L6 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
PLK1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31730000 25483079 29656893 24067368
HDAC1 RREB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610 23752268
HDAC1 ZBTB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26496610 23752268 28514442 33301849
HDAC1 ZMYM3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28242625 26496610 23752268 28514442
TRAF2 MTOR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25241761 14743216
SOX2 NCOR2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 28794006 21532573
UBE2I SMAD4 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217094 15231748
TRPS1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23772552 17391059
HIPK2 UBE2I â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
UBA1 UBE2E2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CHD3 TRIM28 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
PIAS2 TP53 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
CBX5 DNMT3B â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EP300 VHL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KAT5 MDM2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MDM2 NPM1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
UBA1 UBE2G2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
NCOA1 NCOA2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
NCOA2 NR1H4 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRCA1 UBE2E2 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CTNNB1 PPARG â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MDM2 TP63 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
EP300 RAN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33742100 12649209
EP300 ING2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16782091 16024799
UBC HGS â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 12750381 5216384
HGS UBA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19019082 25260751
PIAS2 TRAF2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32296183 22184250
SUMO1 PIAS4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20016603 15831457 16524884
SUMO1 PSIP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 22748127 21110914
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
PARK2 TRAF2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
HDAC6 UBB â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
RNF168 UBB â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
RWDD3 UBE2I â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
NUP153 RAN â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
PIAS1 SATB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20351170 18408014
AXIN1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18632848 26871637 22509369
UBC MDM2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18566590 19166840 17290220 19098711
RARA NCOA2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12503607 9192892 12612084 20543827 9430642 16713569
RARA UBE3A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33995501 9891052 16713569
TRAF5 TRAF2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 32296183 9718306 21903422
MDM2 UBB â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PARK2 UBE2G1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
PARK2 UBE2E2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
TP53 XPO1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
NRIP1 THRA â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
UBB UIMC1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
SATB1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15561718 20351170 18408014
YAP1 AXIN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24976009 29789528
SOX2 CHD3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23667531 28794006
EPAS1 EGLN3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15474027 17353276 17684156 23275444
SMAD4 EP300 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18215124 25514493 10887155 22033265 9679056 14612423 9843571
HDAC1 NR3C1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
NRIP1 RXRA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 8887632 12549917 16189514
SOX2 PIAS1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
RARA SUMO1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24819975 15171703
ATXN3 UBB â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
NR1H4 PPARGC1A â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
BRCA1 MRE11A â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GATA4 EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18252717 27208796 11481322
HDAC1 VHL â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 11641274
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SUMO1 MDM2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18583933 20972456 15876874 21316347 11384992 12393906 12297306 12917636 22411991 15876864 17000718
MDM2 UBE2A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22083959 12640129
KAT5 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
PARK2 SNCA â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BLM TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PIAS1 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RXRA THRA â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HIF1A MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HIPK2 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MAP3K5 TRAF2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PTGS2 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 TP73 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
NPM1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SUMO1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
DNMT1 DNMT3B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
FAF1 UBC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
EP300 PPARG â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SATB1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16630892 12374985 16189514 15713622
BRCA1 BLM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25084169 29656893 26831064 10783165
SETX BRCA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25699710 34112789 25184681 29656893
BRCA1 NCOA2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11085509 14578343 16860316
BRCA1 UBA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12438698 26831064 11278247 15184379 12485996 11927591 12887909 14638690
HDAC1 BUB1B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15388328 19407811
YAP1 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 22234184 8383887
HIF1A EGLN3 â—¼   HYDROXYLATION ✅ 0.88 0.88 mint 5217229 15474027
EP300 PPARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18797151 9407140 10336495
EP300 RORA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16713569 9862959
SUMO1 ETV6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24654937 12626745 26871637 11078523
UBE3A HERC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22645313 29426014 21493713 30257870 30279242 25476789
NRIP1 PPARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9626662 10022764 16189514
PIAS4 SMAD4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12740389 12815042 12904571
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
NCOA1 NR3C2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
UBA1 UBE2A â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
UBC UBE2G2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ARRB2 MDM2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
MAPK8 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NCOR2 ZBTB16 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PPARA RXRA â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HERC2 UBE3A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
NRIP1 RARA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
UBC USP25 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CREB1 EP300 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
CTNNB1 YAP1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
CREB1 ATF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25609649 20102225 1655749 8384217
ATF1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16713569 10945975
HDAC1 BCL6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16147992 10611298 9627120 9753732 15454082
HDAC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10220405 21102443 16713569
BRCA1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26831064 18025037 20016594
HDAC1 CHD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28977666 22939629 26496610 9804427 23752268 20585571 11784859 17827154 28514442 27068747 9885572
EP300 PAX6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10506141 35140242
EP300 HIPK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16917507 29170424
ING2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16728974 16387653 23752268 28514442 18193082
HIPK2 MDM2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16212962 23826318 17349959
CDKN2A NPM1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
NCOR2 RARA â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
TP73 YAP1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
AR NCOR2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
NCOA1 THRB â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
NCOA1 THRA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
NCOA1 PGR â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
NR1H4 RXRA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
AR NCOA1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
HIF1A UBC â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
NCOR2 THRB â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CDKN2A TP53 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
INO80B ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
AR MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
UBE2I ZHX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21988832 23686912
SUMO1 CASP8AP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21338522 19615980 23673342
FAS CASP8AP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10235259
UBE2I CASP8AP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21338522 19615980 23673342
AR PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18386814 16317058
AR CASP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16007156
AR PIAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 18656483 10628744
AR CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18794357 20610535
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
AR SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24119295 21796528 17932034
AR CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 15790678
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
TCF4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12799378 16713569
MDM2 ARRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18544533 21389118 21081496 33649538 32828283 17984062 32450252 12538596 21988832 15878855 26545496 12488444 21466165 11588219
TP53 ATF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
NCOR2 BCL6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16147992 15531890 26728228 23911289 10611298 9824158 9765306 14690607 11865059 15454082 9380707 10898795
TP53 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23852341 19427386
EP300 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17828269 12402037
EP300 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10655477 21212407 19887647 22787115 16713569 11782371 21102443
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DNMT1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19943104 22197621 20631324
BRCA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17873885 11320250 14636569
RXRA CASP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HIPK2 CBX4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17018294
DNMT3B CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20375073 16887905 18974268
SMAD4 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22775504 17452626 24625091
TP53 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15383401 20332115 21478913
PPARG CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22472882 20234816 21159608
CREB1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
TFCP2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
PAX6 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20053773 11584062 17157287
PLAGL1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
MITF CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19067971 15623583 1999537
CTNNB1 CHD8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10921920 10944533 18378692
YAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23607968 22234184 23245941
DNMT1 DNMT3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24423239 16481298 20155458
HIF1A EGLN3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24015760 18264140 26972000 23345396 18063574 16511565 16155211 15721254 30067985 18402654 31239290 15474027 25416956 17353276 17069766
EP300 TFAP2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12586840 11694877 11744733
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
EP300 ZBTB16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15964811
FAM118B SHC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR3C1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15802531 15590983 15289452
FAS MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25241761 11495919
FOXM1 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19276163 20379221 23037713
HIF1A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24015760 16511565 21148070 11641274 17273746
HDAC1 TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18381204 21669397
MITF HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15983061 22012259
HIF1A RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15270719 14742449
HIF1A PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18461556 19490906 11879638
RWDD3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17956732
SUMO1 HIPK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16253240 14609633 10535925 21192925 15958389 15896780 24637324 21145359
HIPK2 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16212962
TP53 ING2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17940011 16024799 12859901
MDM2 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11927554 16904321
MAPK8 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11602589 15688026
TP63 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11714701 9405685 12374749
TRIM28 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16107876
MDM2 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20571051
MITF PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23416000 23477830
PAX6 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11350962 16189514 12756174
RARA NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12138096 16456540 9192892 23975195 9121466 10454579 16606617 17475621 21478865 17363140 20543827 17641689 16713569 10082574 10760302 12665583 20338915
NR1H4 NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14698205 11136553 18391212 20338915 14684751
PPARG NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10347167 15604093 15026545 30813326 11877444 19596656 17704298 30595551 9041124 9121466 9744270 23178929 10339548 16713569 15888456 17513608 22070604 17449869 10731636 20717101 10848596 17468099 11027271 17312272 11500849 23975195 17011503 16373399 10944516
NCOA1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16891307 19194461 18511507
RARA NCOR2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11929748 16219912 19377461 9256429 7566127 17475621 9380707 15604093 20543827 16713569 10082574 9415406 25303530
NCOR2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22395773 21846906
TP63 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
PPARG NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
NR3C1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
NRIP1 PPARG â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19596656 11500849 16189514 11877444 9626662
RARA NRIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21310893
PGR SUMO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19211567 17717077 17020914
PGR UBE2I â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19211567 17717077 17020914
PGR TCF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
PIAS2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14514699
TP53 PLAGL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18431400 11360197
SLX4 PLK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25852190 22902628 31495888 25659891 32707033 19596235
SIMC1 PLK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PLK1 RXRA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RXRA PPARA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15888456 12562861 7760852 34081964 10195690 22205725 23711995 16189514
TP63 PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19458633
PPARGC1A PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21775429 10669761
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
RARA ZBTB16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24821728 21949697 11106752
THRA RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
RARA THRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
XPO1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11074002 23331499
SMARCAD1 TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21549307 18675275
VHL SUMO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20844582 24002598 20300531
TP73 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16413471 21436470 18026135
TP73 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11238924 19815500 10373484
TP63 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278685 35044719
UBA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17597759 24816145 21209336
VHL UBE2I â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20844582 24002598 20300531
ZBTB26 ZBTB6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
NUP107 NUP153 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
HDAC1 ING2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
HDAC1 ZBTB16 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
BCL6 NCOR2 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
NUP214 XPO1 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
XRCC4 TRIM5 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
CBX5 TRIM28 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CDKN2A MDM2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PIAS1 SUMO1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
UBA1 UBE2G1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
UBA1 UBE2L3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
TP53 UBE3A â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
PAX6 MITF â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 16189514 11350962
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
UBA1 UBB â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
PIAS4 UBE2I â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
TNFRSF1A TRAF2 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
BUB1B PLK1 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
EGLN3 HIF1A â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
UBE2L3 UBE3A â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
BLM MRE11A â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CTNNB1 TCF4 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
DNMT1 UBB â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CHD3 HDAC1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
PPARA PPARGC1A â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
RANGAP1 SENP2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CTNNB1 AXIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219694 17318191
TCF4 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219694 17318191
HIPK2 MYB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 15082531 16055500
NCOR2 PGR â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
RAN RANGAP1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
SUMO1 HIF1A â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 20661221 24434214 20026589 17938407 15465032 15876874
UBE2I RANGAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17036045 5219211
RXRA RARA â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5212283 10698945
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
NCOA2 PPARG â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
NCOA2 THRB â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
NCOR2 RXRA â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PARK2 UBB â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
RARA NRIP1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 12503607 16189514 8887632 12549917 14581481 17641689 16713569 25416956 10082574 10531331
SUMO1 SAE1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 15660128 12941704 9920803 12924945 19246003 20164921
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
NCOA2 RARA â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
KPNB1 NUP153 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
PIAS2 UBE2I â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
HGS UBC â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PIAS1 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MDM2 UBC â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
HDAC1 DNMT1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22274925 10888886 15870198 21670149 17707923 10615135 26794444 17967891 20613874 12473678 17934516 23708667 27593931
HIF1A EP300 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 18268343 15154850 12914934 19074848 25192544 22789427 20829524 21148070 17502379 26826385 22075993 16543236 19680224 20603618 19589782 11063749 23618863 26135796 27808477 22219185 15155277 11823643 17906695 19666581 21187066 16189267 8917528 23746844 19940151 19071119 26944191 15261140 24421387 20000859 12778114 14691445 12042299 22684029 12588875 17382325 23966271 15342390 22735262 27320910 26751287 24821806 23448368 11959990 15280364 11940656 19696166 20620956 16081065 22908229 18047470 16847340 22807441 23880760
XPO1 RAN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 20026644 26344197 10779340 22939629 27613868 10944119 12070164 9323133 21909257 32585100
SAE1 UBE2I â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
NCOR2 PPARA â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RNF168 UBC â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SMARCAD1 TRIM28 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HDAC6 UBC â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
RXRA THRB â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
AR NCOA2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
NCOR2 PPARG â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
NCOA1 PPARA â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 NR1H4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 NR3C1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
NCOA2 NR3C1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
RANGAP1 SUMO1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CDK6 CDKN2A â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
MDM2 TP73 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PIAS2 SUMO1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PPARG RXRA â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
SENP2 SUMO1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ATXN3 UBC â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NCOA1 RARA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NCOA2 RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RARA RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
SAE1 SUMO1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
UBC UIMC1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NCOA1 PPARG â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
NCOA1 RXRA â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
UBA1 UBC â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
PPARG PPARGC1A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EPAS1 VHL â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PARK2 UBE2L3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PARK2 UBC â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AXIN1 CTNNB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RANGAP1 UBE2I â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
KPNB1 RAN â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NUP107 SEH1L â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAN XPO1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
HIF1A VHL â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
NCOR2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19223455 16373395 21720703 22508987
NCOA1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15514032 12163482 23145053 11673464
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR ZBTB16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15334066 20610535 16637071
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
AR NUP214 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR TRPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535 15613454
AR THRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17409431 20610535 17721441
AR TNFRSF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
NR2C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 16713569 12949936
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
RAN AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10400640 16713569 18565325
KAT5 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11591700 10364196 19150978 11994312 16713569
HIPK3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9725910
NCOA2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9717843 12588987 15684378 14593076 24239470 15563469 18780293 12810069 16713569 10601285 14966121 10935543 10454556
BRCA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11085509 16713569 11016951
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
NRIP1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9368054 16527872
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
UBE2I AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
MDM2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17974989 26411689 27835608 26973243 15640443 12145204
NCOR2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 23331499 11923464 15062576 14593076 17356171 22508987 12441355 12771131 20812024
PIAS2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11117529 9920921 12177000 16713569 11477070 12764129
MAPK8 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24424504 21512132 21820033 16282370
PIAS4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16713569 14981544 11439351
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
AR UBE2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
AXIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 20128690 20531388 16890161 27902311 22509369 18593713 16199882 23331499 9482734 21071413 26496610 19244247 22773187 17318191 10196136 18988627 17208333 19131971 24976009 22682247 10228155 12805222 12000790 10488109 9501208 9601641 18632848 9554852 19166851 23959799 12421363 9734785 11940574
BCKDK DLD â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22956686 15166214 24449431 15576032
NCOR2 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 9380707 15531890 10611298 15454082 23911289 16147992 9824158 10898795 14690607 11865059 9765306
BLM KAT5 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12080066 11399766 22653443 24239288 15806145 11781842 16713569 15364958
BRCA1 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 XPC â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
CREB1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9528858 19882681 18160048 23447579 11704836
UIMC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17525341 17525342 17525340 17621610
PLK1 BUB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 23695676 19228686 17376779 27568981 23079597 26259146 27308323 17785528 19015317 22566210
HDAC1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20580679 19182791 21685935 21184735 24424621 18794357
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
CDKN2A CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 17881001 26186194 23602568 9751050 11739795 11556834 9380698 15232106 16713569 17955473 10491434 16915296 17909018
CDK6 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17208333
EP300 CDKN2A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
DNMT3A CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 26350239 19786833 20620135 17490527
TP63 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9151818 19340300 19554267 21093383 19672307 8995628
TP73 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12766778 18555006 11870517 18829110 11309270 14733783
TP53 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 16103197 22467867 18555006 8631601 11402335 19649205 22020338 21164364 17265068 16764954 15775976 22056554 18275833 21483786 10348346 19216023 12384561 12091906 19901969 11360201 15205322 11818069 21892281 10980602 11739748 11559812 24672805 10097151 17907153 19244234 15361884 10652576 9436028 21447739 20569441 21555589 21637567 10816133 9774662 19240179
DNMT3B CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23397112 18006804 22461910 17149367 21757290
NPM1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16957780 20208519 15289458 16199867 16915296
CDKN2A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15856024 15989956 9724636 19960022 12740913 17158541 12640129 19590512
CDKN2A MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 57.0 1.0 Omnipath 12167711 18541670 23416275 9529249 17426254 12630860 17116689 12085228 15856024 10822382 19166854 12209154 12740913 17158541 16915296 17909018 25809483 9653180 14612427 22120712 16173922 10871849 18418067 24769896 9724636 21133853 10801444 19049976 9529248 16107876 18813780 20713054 18467333 15355988 18583933 20395212 11223036
TRIM28 CHD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18082607 11230151 24018422 16169070 21642969
CHD8 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18378692 15367660 11744694
CREB1 PTGS2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11579131 15187187 15749884 16007092 16713974 17404308 20547845
CREB1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 20954072 21668646 15213229 11092885 18515110 19925797 22919060 17559081 16007171 17505916 17186551 15221958 11668179 11526505 24378735 20032081 17524357 16256955 19797430 16319525 21268077 15289885 17632087 17962194 14645533
CREB1 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19937254 10841026 17083486 22496449 19067970 18039926 21519923 16327152 24267286
CREB1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20359506 17451429 17018277 21156859 11557984 22980225 15653680 19583954
HIPK2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20573984 19690332
NR3C1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20203101 16713569 8449898 7621901
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
CTNNB1 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
PPARG CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12021175 15190077 20303941 14764597 19075513
CTNNB1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11396184 15592796 12154096 17945188
CTNNB1 TCF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12086873 11943708 13679048 15806138
RXRA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12771132 25241761
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
CTNNB1 TCF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 24532795 11713475 18281465 25402006 16724116 12799378 12944908 12727872 23331499 15060161 17412698 22080605 21743491 17875931 12657632 17983804 20126258 17318191 24798214 24876153 29361949 17909039 23449499 22699938 18595660 9308964 16007074 15331612 11713476 15665104 17072306 15525529 17962194
CTNNB1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25721714 16847334 25168821 19495794
HIF1A EGLN3 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A EGLN3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19828020 15156561 20727020 15823097 22555025
EPAS1 EGLN3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 5.0 1.0 Reactome 12615973 12788921 19208626 18337469 18184961
HIF1A EGLN3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 16.0 1.0 Reactome 11292861 15652751 17182618 12615973 12788921 11598268 11292862 21335549 17434750 15474027 15247232 12351678 12912907 15987702 22286099 18337469
EGLN3 EPAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12788921 23275444 17684156 17353276 15474027
EGLN3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 17145710 15652751 26972000 15721254 16391536 16511565 24990963 12351678 31515488 24145445 17353276 15474027
EIF2AK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17451862 16083285 1088347 10082513 10348343 10884347 16552184 9315650 9737981 19413330 16713569 10747897
EP300 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12057991 17395887 17237818 12471036
ING2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16782091 16024799
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 11804596 19407812 15175157 19788416 12660246 19218448 10648616 15454570 16998810 25675294 15893728 18663001
EP300 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15731352 20448036 10490106 9920895
EP300 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15965232
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9660747
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
HIF1A EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20513003 18174278 16924414 19030186
ETV6 SPTBN1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 29025582 28028030 24854988 28751768 19345670 17268528 23168613 27795560 30559310 31066629 17764812 16761019 21705501
FAS FAF1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
TRAF2 FAF1 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
FAS FAF1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
TRAF2 FAF1 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
TRAF2 FAF1 â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
TRAF2 FAS â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
TRAF2 FAS â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
TRAF2 FAS â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
TP53 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10101800 12788915 15580300 16317104 16322229 14719118 16557594 20797428 11103825 19615968 7539102 12447615 12944915 12963547 11313989 16951143 9841917
TP73 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18343378 16741250 15805279 19615968
HIF1A FOXM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22831955 19097132
FOXM1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15817462 16314512 16809346 17173139 15531365 15654331 15689977
PLK1 GOLGA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12839990 20937827 15678101 11447294
UBE2I HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
SUMO1 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
HDAC1 NCOR2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 NCOR2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
NR3C1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15826950 16762839 18762022 18028994
UBE2I HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12820959 15340381 11960997
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
HERC2 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
HERC2 RNF168 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20023648
VHL HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
HIF1A VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12205091 15930297 21887475 22150821 22396654 15962286 23159849 17482131 17140440 16883594
HIF1A TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16896927 17053163 15611046 19211927 21209004 21057546 21055290
HIF1A PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19106818 16397226 21149600 14507857 16818642 23144021
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
MDM2 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 15880652 25535359 12606552 25447306 17234751 19696166 10640274
VHL HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 123.0 1.0 Omnipath 17145710 21332579 24857547 12682018 26496610 11292861 11024059 15060148 16278378 12586829 17353276 12004076 12205091 17339318 10823831 11226425 21602890 16862177 15611064 12351678 16140212 11865071 26037477 16611863 10973499 23401859 25361009 11331613 18305400 25438054 14691445 17047048 12538644 22932900 18985005 26735336 21358672 18323857 10878807 19147576 16511565 17973296 23413029 24316222 11986208 12808024 12464182 23318261 22369643 19940151 15721254 20724477 21335603 16391536 23387829 18694926 26743088 14556007 18264140 10353251 15082527 11358837 11292862 11566883 12050673 19123984 17558023 27281823 15805242 11641274 25500545 34174286 24899725 12606543 32535973 17132228 24015760 12086861 11504942 35589690 26215701 22351759 12925778 18222538 17986458 14600153 10944113 23580587 26611735 18426857 20049704
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
HIPK2 TCF4 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10391247 11925430 12851404 15082531 17349959 18974774 19828042
TP53 HIPK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16343438 19642869 18809579 18483253 19828042 21248071 18336191 11925430 11740489 11532197 17658469
SUMO1 HIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21145359 15896780 10535925 14609633
HIPK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19828042 25210797 20508833 22545114 23814485 19731416 11740489 20171273 11875057 16212962 16729035 23700162 23945296 24101931 27308326 16713569 23536002 28107201 27901482 27019364 19714248 22011578 27308327 15896780 16601678 23316480 24145406 28122345 21192925 17906639 25313037 27689990 20849851 21258400 17203463 19128456 17349959 25364713 11925430 20418953 24829283 22935610 21855806 28893313 23717325 11780126 19946469 21057547 23293771 27787517 26942128 15865933 17210684 17332358 22110707 22889244 23091802 24211575
HIPK2 PAX6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16407227
KAT5 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
KAT5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17188038 15310756 18280244 16601686
RAN KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 10779340 8909533 11024021 9214382 20658144 8576188 26496610 9102465 9135132 10944119 10037787 9045717
NUP153 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 35044719 10749866
TRAF2 MAP3K5 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TNFRSF1A MAP3K5 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TNFRSF1A MAP3K5 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TRAF2 MAP3K5 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TRAF2 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 10688666 18292600 9774977 10523862 16636664 19805025 16713569 17700517 17015619 17724081 15310755
MAP3K5 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 17634293 20348951 15247305 21785467 12194869 12221076 18818208 18029441 19667122 21726807 16760468 21212517 19749799 26147002 25310587 33573023 26375285 16648474 15944157 7839144 12456653 25915038 26853469 21856198 31575661 10521505 25702873 19029119 20156337 16928747 15020250 20452983 15242986 18570871 16845370 20871632 21040800 27203743 19783996 21931634 23608534 21697492 25619840 26964622 12758252 16632641 28881794 17210579 34048499 20921231
TP53 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22607268 23376463 18374905 15958553 10854211 22353755
MAPK8 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12351702 18337589 9482836 9199329 18669648
MAPK8 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16551633 10383391 10938283 16038797
MAPK8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 11108663 12531896 16713569 11283254 10706102 19651615 27147566 9724739 15538975 9732264 10581258 10436023 17570479 9393873 11896587 12514174 15580310 18813780 11078726
MAPK8 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10383391 15657432 21272161
MAPK8 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9030579
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
TP73 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20921405 15734740 20156675 10469568 11245471 10207051
UBE2I MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
PLK1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12383858 19833129 23948487 24265276 26754547
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MDM2 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19805293 22056774 17290220
MDM2 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 18499675 17700533 26025930 25417702 19218448 21088494 10321734 10469568 10435614 20588255 25301064 10207051 11223036 21261729
SOX10 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10973953 10982026 15760336 10938265 16494873 19026785 10942418 16921166
MITF PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9466887 23610061 17277739 15978250
UBE2I MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10673502 16713569 10694430 16029420
SOX10 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10973953 10982026 10942418 10938265
MTOR PPARGC1A â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MTOR PPARGC1A â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MTOR PPARGC1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MYB NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16263717 15044598 22516378
UBE2I MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11779867 16713569 22910413
NCOA2 NCOA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
NCOA1 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11698662 10731636 9626662 12163133 21775429 15888456 9407140
NCOA1 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12529333 7481822 10757795 19706513 21273440 16352595 16728408 10722692
RXRA NCOA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
NCOA2 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12612084 20543827 23331499 9192892 9430642 16713569 12503607
NCOA2 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 11500849 9238002 17513608 21071413 15026545 18988627 18584035 10944516
NCOA2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 12612084 11981034 15657427 23331499 21071413 9430642 10748178 11514567 18988627 11851396 17947383
NCOA2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11266503 29170386 12151000 9920895 9590696
SMAD4 NCOR2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
PPARA NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19955185 11845213
NCOR2 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 10757795 12771131 17347654
NCOR2 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 15175761 16219912 20364085 15604093 17704298 17312272 23703729 9121466 19147680
PLK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19651622 17081983 20068231 27619510 15190079 20352051 19413330
NPM1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 23443559 15144954 16740634 15310764 16376884 12080348
RXRA NR1H4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
RXRA NR1H4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 19883617 7760852 10744760
NR3C1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24811171 27777311 10649448 8754811 11279134
NR3C1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10631313 18945810 10827178 18657608 9918831 19797430 10701683 18650268 16198345
NRIP1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10659697 12773562 11266503 9920921 16189514 10364267
SUMO1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16189514 12193561 12144530
NR3C2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
NR3C1 NR3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
RARA NRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 12403842 17641689 8887632 25416956 14581481 16713569 12503607 10082574 12549917 10531331
NRIP1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 12403842 17641689 8887632 25416956 14581481 16713569 12503607 10082574 12549917 10531331
NRIP1 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23331499 10022764 9626662 16189514 9774688
NUP214 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 12917407
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
UBE3A PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 9891052
PIAS1 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16524884 22578841 19217413 18806873 14609633 11583632
PIAS1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14514699 21988832 23331499 15028714 15231748
PIAS1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 15133049 10380882 20805487 11867732 16713569 11583632 11788578
PIAS2 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16204249 21988832 25416956 19217413 16189514 14609633 16524884 12764129
PIAS4 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
PIAS4 TCF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12727872 20211142 15831457
PIAS4 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 12815042 12740389 12904571
TP53 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17172872 17981789 15024021 22405092 20962589 24076372 23948487 15016801 22184120 19713933 16369493 23474762
PLK1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20805321 16930555
PLK1 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19004816 21849493 28067771 19889641
PLK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22653443 19833129 16753148 23948487
PLK1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18418051 23948487 18174154 22084676
PPARA PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11840453 12388637 11971025 18648741 11578780 11412039 11007963 20022932 21323895
PPARA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12941763 16226723 20706641 17261671 18769491
RXRA PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 10195690 12562861 16189514 11237216 10708554
SMAD4 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 16580992 12524424
PPARG TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 14702344 17625041 31023188 17995524 16321227 18615188 14693716 12711314 16611854 18991162
PPARG PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11278336 16506021 19578162 20234816 10827178 14555539 11412039 19997048 20656057
PPARG PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16513826 32991581 29182484
RXRA PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 12763030 25609649 20211142 11877444 16504037 17579352 16713569 9065481 22205725 23331499 22363753 10854698 19147680 19043829 12591919 9568716 10882139 10935544 17980149 26260846 21478865 14587029 23711995 9121466 18217139 31547433 7838715 19047629 23275339 21833030 12966085 17312272 11237216 15888456
UBE2I PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19692572 15507114 26192107
TP53 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21187340 16713569 11687965 21763744
RANGAP1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7744835 8146159 9219684 16189514 10394366
UBE2I RANGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 23395904 16194093 16713569 18691969 18538659 21988832 21098080 21139563 17036045 11853669 22194619 15931224 26496610 19549727 9497385 16732283 20501649 17353931 20719936 12924945 16820290 14578449 18706886
RARA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 15528208 19345331 16713569 16769902 21988832 23331499 14521715 15604093 21071413 10828175 10698945 18988627 12393611 25303530 16224062 25241761 1310351 21478865 17641689 7760852 9415406 9121466 7705655 9582446 15171703 10882070 1314167 12052862 31700049
RNF168 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RXRA TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18615188 8264664 16611854 18007025
THRA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11018031 23331499 15604093 1331778 1314167 19422879 11117530 16189514
THRB RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9582446 23331499 9368056 15604093 10677278 19211732 9162076 19422879 7746322 9171239 9415406
SUMO1 SENP2 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 16253240 15487983 16738331 12192048 11896061 17591783 14563852
TGFB1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12767520 22710166 19010789 16474430 19920116 22943793 17934056 20519943 12809600 21900405 11133108 14557817 15548370 17673906
SMAD4 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10964912 15647271 10843986 21968601
SUMO1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14514699 23331499 21071413 12813045 12740389
UBE2I SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 21988832 31515488 16189514 15637079 16713569 12621041 29892012 15231748
YAP1 SOX10 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
SUMO1 ZBTB16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17498654 18348865 14527952
TP53 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12732139 10618379 22264233 23706820 14514686 8183578 14761612 16138117 18593586 23063463 8119773
TRAF2 TNFRSF1A â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRAF2 TNFRSF1A â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRAF2 TNFRSF1A â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TNFRSF1A TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 26212014 8565075 8943045 8612133 16713569 16611992 22179575 11821416 7544915 12721308 21741934 10795740 21119000 19150425 27321185 25241761 15115707 18776134 15743837 15485837 20448643 12887920 24735611 20333651 18022363 19815541
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53 XPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12771027 22336944 12242345 23050045 16357511 12967652 15927209
UBE3A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 23040663 7724550 9450543 16713569 16493710 15001357 17131388 9143503 19364824 31971989 11027293 9688277 9369221 1661671 7708685 12620801 8090726 8380895 26789255
TP53 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12771027 9346961 10779360 21340684 19004803 10367887 20066118 12496474 12242345 20457558 20182602 10962562 6396087 9892649 12967652
TP53 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18172499 18695251 24667498 22056774 17290220 17592138 12421820 18413597 20173098 19556538 21857681 17470788 18359851 19805293 19196987 12640129
TP53 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11238924 18431400 21508668 9891077
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
YAP1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 15678106 17110958 35044719 19111660 19788416 21808241 18280240 18640976 25283809 15893728 11278685 17889669 27292796
UBE2I TRIM28 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17942393 17079232 25114211 18488044 17298944 18082607
UBE2I UBE3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15340381 12820959 18997815 15668399 18298802
UBE2I UIMC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19549727 17698038
TDP2 TDP2 â—¼   KO_DOWN_REGULATES ✅ - -2.0 1.99 PKG 28854368
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
XPC TFCP2 â—¼   KO_UP_REGULATES ✅ + 7.57 7.57 PKG 28854368
SETX SETX â—¼   KO_DOWN_REGULATES ✅ - -8.56 8.55 PKG 28854368