Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
AR KHDRBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18273831 20610535
FMR1 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
CALCOCO2 ZNF451 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CALCOCO2 FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CDC5L HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUV39H1 CDCA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A CDCA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
CDCA4 ZNF451 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
HTT CREB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD4 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9689110
CREB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
E2F6 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12004135
FAM118A ZNF451 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
ZNF451 FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 PCBD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 KHDRBS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
PLEC HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZNF451 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PLEC KHDRBS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KHDRBS1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD4 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PRPF40A PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PLEC ZNF451 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PRMT1 ZNF451 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
ZNF451 PRMT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
UBE2I PRPF40A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD4 PRPF40A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ZNF451 PRPF40A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RAP1GDS1 ZNF451 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ZNF451 RNF40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UBC SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8308197 22045334
SMAD4 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8308197 22045334
UBE2I SNIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SNIP1 ZNF451 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SUMO1 TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20016603 25114211
ZNF451 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
UBE2I TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
ZNF451 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UBE2I ZNF451 â—¼   PHYSICAL_INTERACTION 809.0 0.8 STRING 36370105
MYC CDC5L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
UBE2I SMAD4 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217094 15231748
CDC5L SUMO1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19596686 20467437
TP53BP1 UBC â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
SNIP1 SMAD4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10887155 16189514
KDM1A CDC5L â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17043677 31413325 20467437
MYC KDM1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 23455924 32296183 29467282
MYC UBC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 16996503 19131971
CALCOCO2 UBC â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
PRMT1 PRMT8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PIAS2 MYC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17418410 16352593 18923429 17471507 11283613 30415952 20426839 19786833
MYC PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17146439 21150319 32592588 30415952 15735755
FMR1 FXR2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
AR PIAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 18656483 10628744
AR KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 16079795 22052438
AR SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24119295 21796528 17932034
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
MYC BIN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21447800 10380878 18348166
SMAD2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9689110
E2F6 ZNF451 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12909625
SMAD2 MYC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28205554 11804592 28628118
MYC ZNF451 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
PIAS2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14514699
SUMO1 PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15017387 15561718 28851805 16501610 19217413 22155184 22875967 24654937 31879127 21779164 20188669 9885291 9452416 17081986 21098080 22406621 18625722 21305000 17344210 17027752 11160742 19380586 23604351 23830076 17081985 9427741 11080164 16189514 23028697 21057547 19015637 20972456 8806687 20826694 24190887 25497731 17036045 11948183 9756909 18474224
PML UBE2I â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PML SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15356634
SNIP1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10887155
CDC5L EIF4A3 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
PIAS1 SUMO1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CDC5L SNIP1 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
BIN1 MYC â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
PIAS2 UBE2I â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
PIAS1 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
FXR2 FMR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 21653829 32296183 24981860 7489725 29395067 8668200 10567518 30217970 24778252 24722188 16713569 25416956 26949739
PML SUMO1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PIAS2 SUMO1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMAD2 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
AR UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17409431 20610535 17721441
KDM1A AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17277772 16079795
UBE2I AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
PIAS2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11117529 9920921 12177000 16713569 11477070 12764129
AR UBE2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
PRMT1 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10748127 12529443 16713569 15782174
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
MYC PIAS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21811581 22053792 12545156 17471507
MYC SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
PIAS1 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16524884 22578841 19217413 18806873 14609633 11583632
PIAS1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14514699 21988832 23331499 15028714 15231748
PIAS2 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16204249 21988832 25416956 19217413 16189514 14609633 16524884 12764129
SUMO1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22875967 9756909 25497731 17036045 21057547 18931695 19217413 8806687 16189514 17081985 11080164 11948183 9885291 19380586 17344210
SMAD4 SMAD2 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
SMAD2 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16052471 11376804 11456453 9812998
SMAD2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 15613484 17145710 25609649 15817471 20211142 21532621 24584437 18729074 23788427 12419246 16916642 9288972 9892009 21454478 17510063 10531362 15231748 11027280 12167862 21988832 9389648 23331499 12543979 18568018 21071413 19135894 18511908 15467747 12808092 11927552 25514493 15350224 18988627 12732634 10878024 9111321 9311995 9346908 10199400 11264182 12957874 11114293 15761153 11274206 12621041 17272273 24157709 26555259 12374795 22442258 10781087 15922743 11102446 17591701 18783722 16751102 19139564 19917253 9346966 21297662 17283070 12794086
SUMO1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14514699 23331499 21071413 12813045 12740389
SNIP1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 10887155
UBE2I SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 21988832 31515488 16189514 15637079 16713569 12621041 29892012 15231748
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368