Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
UQCRHL RNF40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSP90AA1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0908908106 19805354
HSP90AB1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21730179 1105160108
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
AR HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 21125667
CDK9 NCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
CDK9 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
HSPA5 SUPT6H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RNF20 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZCCHC12 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PSMC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LEO1 SUPT6H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RNF40 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NCBP1 PARN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7898576 20379136
NCBP2 NCBP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
RNF40 PSMC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RB1 TP53BP1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
ZNF451 RNF40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRIM51 RNF40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TERF2 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 21824286 8202878
YY1 TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
TP53 UBE2A â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CDC73 SUPT6H â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CDC73 RNF20 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
ESR1 PARN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
PAF1 SUPT6H â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
UBE2A UBE2B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 25582440
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CDK9 TP53 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CDK9 RB1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
NCBP1 RNF40 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
DUSP29 RNF40 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
EP300 HIST2H2BE â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
CDK9 CDC73 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17643375 26659056
LRRK2 DDB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31046837 24725412
LEO1 PAF1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
NCBP1 RNF20 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
CDK9 PAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21873227 26659056 24837678
IWS1 SUPT5H â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
TERF1 ATM â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15314656 18160036 11375976
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
ATM RNF40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21763684 26184323 17478428
TP53 DDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16357511 19382146
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
ESR1 FOXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25303530 18414489
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
MSL2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19788416 19033443
RNF20 RNF40 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
YY1 RNF40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
UBE2L6 UBE2E1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16112642 16428300 16122702
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
RNF40 UBE2B â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
RNF20 RNF40 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
RNGTT SUPT5H â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
RNF20 UBE2A â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
CDC73 SUPT5H â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
PAF1 LEO1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
RNF20 UBE2B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RNF40 UBE2A â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
PAF1 SUPT5H â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
PAF1 CDC73 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
IWS1 SUPT6H â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
NCBP2 NCBP1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11545740 24981860 9933612 22939629 26496610 26382858 26264872 31448526 26344197 17190602 32814053 12374755 29997244 29101316 31467278 22365833 29395067 19668212 16189514 7478990 23665581 12434151
LEO1 SUPT5H â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
TP53 TP53BP1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
MSL1 MSL2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SUPT5H SUPT6H â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
NCBP1 NCBP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC73 LEO1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC73 PAF1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
LEO1 PAF1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
HSP90AA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1525041 19805354 20048054 15861399 17974989 26342197 17353003 26196320 16713569 27903893 1540595 21157430 19706771
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
ATM TERF1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11331603 11877377 12607003 15140942 15459660 15964794 16163361 17303408 22266654 22634377 23847781
ATM TERF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 17717821 15314656 17570479 23732473 26586433 11375976 22266654
ATM TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16223874 17525332 15314656
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
ATM RNF20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21763684 21362549 26184323 17525332
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
CDK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24173284 9372954 11483158 9315650 19413330 19664995 23603988 24202322 11709713 16083285 1088347 16552184 10884347 24286312 10747897 17942552 16741955 17287340 92065884 12064478 10348343 14702041
CDK9 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8870681 12037672 8170997 9258347
CDK9 SUPT5H â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10757782 16327805 16427012 26399478 11575923 11145967 19941815 25849141
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
YY1 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16452489 15899857 15760841 8972185
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
SUPT5H NCBP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12653964 10757782 9857195 9450929
SUPT5H NCBP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12653964 10757782 9857195 9450929
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
RB1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12588874 11118439
RNF40 RNF20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21362549 16307923 19410543
RNF20 RNF40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21362549 16307923 19410543
YY1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10787423 10634504 8816507 10505791 18391986
TP53BP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25579814 12110597 25837623 16713569 14978302 22653443 26022179 27546791 8016121 12351827 15611139 15364958 14985081 19433796 17805299 25651062 11877378 17634560 22084066 20307547
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368