Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
JUN POLD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10978529
CLSPN UBE2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18451105
UBE2B H2AW â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080676 0910267107
H2AW UBE2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080676 0910267107
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
AR TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12775765 21734264
TAF1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18684994
CHEK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5218401 16511572
RPA2 CHEK1 â—¼   COLOCALIZATION 2.0 0.8 intact 20639859 8010047
UBA52 CRMP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RPA2 CRMP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CRMP1 UBE2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SP1 CRMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18524846
NFKB1 CRMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18782567
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
FOS MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10348347 12173040
FOS NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20188076
UBE2N HLTF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18719106 0805685105
HLTF UBE2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18316726 0800563105
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
UBC JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
RPA2 MED31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MED31 UBE2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 POLD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11375983
POLD1 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 10852724
RAD18 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RPA2 UNC119 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SHPRH UBE2V2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17108083
UBC UBE2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 5211616 10388568
UNC119 UBE2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBR1 UBE2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
BRE1A UBE2A â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 19410543 24837678 28031328 21443952 25582440
HNF4A SP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 15651981 16713569 19115260
UBE2N UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
TP53 UBE2A â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
POLD2 POLD3 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PCNA UBA52 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
CDC73 RNF20 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
UBXN1 BIRC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25681446 18775313
SHPRH HLTF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21396873 18719106
UBR4 UBE2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19549727 25582440
UBR4 UBE2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19549727 25582440
RC3H1 RC3H2 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
RNF4 UBE2N â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
BRE1A CDC73 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27462432 32296183 22021426
UBR3 UBE2A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19549727 21816346 25582440
UBE2A UBE2B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 25582440
UBE2B UBR3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19549727 21816346 25582440
CHEK1 CLSPN â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HERPUD2 UBE2B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
RAD18 RPS27A â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
FOS PIN1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32296183 16123044
HNF4A NR1I2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15331348 16455805
UBE2A UBR2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
UBA52 UBR5 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MDM2 UBA52 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
TAF1 JUN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11316804 16713569
UBC MDM2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18566590 19166840 17290220 19098711
TP53 PIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 12397362 5215850
TP53 UBE2D1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
PFDN6 VBP1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
POLH UBC â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
RAD18 PCNA â—¼   UBIQUITINATION ✅ + 0.86 0.86 Signor 19706603
UBE2B BRE1A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 19410543 27569044 21443952 28514442 25582440
TAF1 FOS â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16713569 8065335
RNF4 SP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10617653 21983342 26511642 34550526
UBR2 UBE2B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20080676 14585983 32366662 25582440
PCNA UBC â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
RPS27A UBR5 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
PFDN5 VBP1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MDM2 UBE2A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22083959 12640129
UBC POLH â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17304240 16763556
UBA52 UBE2V2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
UBA52 UBE2D1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CTR9 WDR61 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CHEK1 TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
POLD2 POLD1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 31449058
RTF1 CDC73 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15923622 20178742 16024656
SP1 NFKB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33572115 7933095 16740634 18083845
UBA1 UBE2A â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
UBE2B UBR1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
POLD1 RPA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PFDN2 VBP1 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
HLTF RAD18 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
RNF4 UBE2D1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
PARK2 UBE2N â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RAD18 PCNA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21967848 28924044 21227930 20675655 32701997 21858012 20064529 28831681 33508099 17108083 18363965 23345618 26170230 17720710 24958773 15359278 31873223 18245774 30700555 31887036 30563767 20600238 22904075 31160570 27377895
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
PIN1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29225075 11432833 16713569
SP1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25879517 16478997 17215518 16713569 33572115 10506225
TAF1 MDM2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9388200 16713569 17237821
HLTF UBE2V2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
PFDN2 PFDN5 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
LEO1 WDR61 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
BIRC2 UBE2D1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
AR MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PCNA HLTF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
HLTF PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18719106 26350214
TP53 POLD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19861536
POLD2 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16000169 10852724 16510448
AR PRKCD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17553165 17178875
AR CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 17522055 18687691
NFKB1 BIRC2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 21725609 23178297 23572150
JUN CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10700231 20566634 19959471
UBE2A CRMP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCD CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 25639486
CTNNB1 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12944908 25241761
LEO1 CTR9 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18469135 20305087 27173435 24981860 22532828 26344197 22939629 26496610 20178742 15632063 16024656
UBE2N HERC5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16112642 16428300 16122702
UBE2B HLTF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
TAF1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9388200 17237821 10891494
TAF1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9388200 17237821 16713569
NBN RPA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
NBN RPA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
SP1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20427719 20538607 9151857
UNC119 PIN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCD PIN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
SHPRH RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
UBE2N RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2V2 RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
RNF20 RNF40 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
UBE2N SHPRH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
UBE2B SHPRH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
SP1 TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9677424 9325332 8955122
UBR1 UBE2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UBE2N UBE2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2B UBE2V2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
PARK2 UBA52 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
RPA2 RPA3 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
RPS27A UBE2V2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PFDN2 PFDN6 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
RNF40 UBE2B â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
UBE2N UBA1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 27173435 14517261 29537486 18678647 30097011 27182664 25527291 33619271 31638574
RNF20 RNF40 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
RPS27A UBE2D1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
PARK2 RPS27A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
POLD2 POLD4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
UBA1 UBE2N â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
RPA3 RPA2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24126761
PFDN5 PFDN6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
POLD3 POLD4 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CTR9 CDC73 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
RNF20 UBE2A â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
UBC UBR5 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
PCNA RPS27A â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
UBA1 UBE2B â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
JUN UBA52 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RNF20 UBE2B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
UBA1 UBE2D1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
HLTF UBE2N â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UBE2B UBR2 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
UBA1 UBA52 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RNF40 UBE2A â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
RPS27A UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBE2N â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
RPS27A UBE2N â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
BIRC2 UBC â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
RPS27A UBA1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
UBC UBE2D1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
MDM2 UBC â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
POLH PCNA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 23761444 21855803 23388460 28831681 22989887 20129057 23042605 26988343 21791603 23345618 11585903 27770570 20159558 16763556 15149598 16189514 30963698 15342632 31796584 24474685 25766642 30563767
CDC73 WDR61 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
HLTF PCNA â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
RPA1 TP53 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MDM2 RPS27A â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
PCNA RAD18 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPA1 RPA3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPS27A TP53 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CDC73 RTF1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RAD18 UBE2A â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
UBC UBE2V2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
UBA1 UBC â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
PCNA RPA1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MDM2 UBE2D1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS27A UBA52 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTR9 RTF1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
LEO1 RTF1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PARK2 UBC â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
POLD1 POLD4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
POLD2 POLD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC73 LEO1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC73 CTR9 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 VBP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD18 UBE2B â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPA1 RPA2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CTR9 LEO1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN5 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN5 PFDN6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN6 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RAD18 UBC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
UBC UBE2N â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPA2 PCNA â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA POLD4 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA POLH â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15703371 16337601 16337602 16697054 17035102 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 22021614 22266823 22562137 23065650 23414611
PCNA POLD2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA CHEK1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA POLD1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA CLSPN â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA POLD3 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
RPA2 PCNA â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA CHEK1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA CLSPN â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA POLD1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA POLD3 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA POLD4 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA POLD2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA POLH â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15703371 16337601 16337602 16697054 17035102 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 22021614 22266823 22562137 23065650 23414611
UBE2N PCNA â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10880451 16224103 16518696 17652783 18157158 18196958 18525240 18647995 19217833 19258535 19851286 20675655
RAD18 PCNA â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10884424 15280666 15688063 16611994 16824193 17652783 18157158 18196958 18363965 18498753 19013543 19258535 19396164 20129063 20675655
PCNA POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
JUN PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22550165 19940138 1352831 15205327 23078099
UBE2N PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 18772547 12820959 18525240 19459846 19258535 19440234 17652783 15147722 10880451 15169778 19851286 10722742 18647995 18006823 18157158 16224103 20675655 16518696 18196958 15340381 10721693
RAD18 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18363965 19706603 17652783 18196958 18498753 20129063 21227930 10884424 19013543 18157158 15280666 19258535 16611994 19396164 20675655
SHPRH PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 19706603 17652783 18196958 19851286 16789823 18719106 18525240 18647995 18157158 10880451 19258535 16224103 20675655 16518696
UBE2A PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18363965 10884424 12820959 19459846 19258535 19440234 17652783 15147722 15169778 19706603 18498753 12226657 20129063 10722742 18006823 18157158 16611994 20675655 18196958 15340381 19013543 15280666 19396164 10721693
PCNA POLH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20129057 20159558 24474685 16357261 16189514 19208623 30963698 15342632 21855803 15149598 23042605 21791603 23761444 23345618 16763556 11585903 23388460 25766642 26988343 27770570
PCNA POLD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24022480 9038370 16510448
POLD4 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD3 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD2 UBE2B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD2 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD1 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD4 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD3 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD2 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD2 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 9286699 12403614 16510448
RPA3 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CHEK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
CLSPN CHEK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
CLSPN CHEK1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
RPA3 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 CLSPN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 18451105 15707391 16123041 21680713 22655267 12766152 16963448
NFKB1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14576180 15517885 20159994 12165860 16619263
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
AR UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17409431 20610535 17721441
MDM2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17974989 26411689 27835608 26973243 15640443 12145204
AR JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11577103 11518798 9211894 8798722 16713569 9591784 17721441
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
NFKB1 BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15050749 17673602 12687011 15756023 9733516 12010810 18566231 16453001 20103608
CDC73 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 16630820 23331499 21726809 18988627 29774127
TP53 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15145945 15988033 19235838 10516009 21478095 14984207 19427386
SP1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9349726 12907235 18355800 10072762 19145069 21131823 22415074 15064717 15951157 16105842 23184467 15899840 12773549 12907249 10542271 16518840 11231912 19433067
TP53 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21340684 20066118 20457558 20182602 6396087
CHEK1 RPA3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TP53 CHEK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21546904 11158294 20190799 19435816 18632613 15016801 19395378 11152453 18753293
CHEK1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22152481 23180782
CHEK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 20950777 18778462 25545885 18677104 20860841 15798197 19793801 22891162 16511572 23852422 16713569 15865930 11551930 19923893 15467443 11709713 21748595 17116885 15659650 17582221 26384650 10673501 17384638 23966620 23892398 17118344 9765199 15140942 19788416 10801407 18319725 12781359 12897801 25823026 15459660 23296650 15024084 17296725 17102137 11896572 17339337 19933256 20526329 28140789
CHEK1 UBE2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158510 20068082
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
CTNNB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20300972 19671687 16007074 9990071
JUN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17146436 18347071 16007074
PIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16713569 11533658
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
SP1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17626239 10082538 9528985
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
TP53 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11818510 16895524
SP1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19540905 15651981 23307400
HNF4A NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12774017 15331348 12601364 18305375
NFKB1 IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15265881 16982926 11877397
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
PIN1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 11432833
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
PEX2 UBE2D1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21554508 19208625 17726030 18359941 10562279
PIN1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12397362 12388558 17906639 12397361 21741598 16713569 24982848 21900206
POLD4 POLD1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD1 POLD3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 UBE2B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD4 POLD1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12403614 16510448
UBE2B POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD4 POLD3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD3 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD4 POLD3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD3 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
UBE2B POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD4 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLH RAD18 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10884424 12466554 14657033 15189446 15688063 16337601 16337602 16611994 16824193 17035102 17652783 18157158 18196958 18363965 18931676 19013543 19217833 19225445 19258535 19396164 19622404 19686080 20129063 20675655 22266823 22562137 23065650
POLH RAD18 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10884424 12466554 14657033 15189446 15688063 16337601 16337602 16611994 16824193 17035102 17652783 18157158 18196958 18363965 18931676 19013543 19217833 19225445 19258535 19396164 19622404 19686080 20129063 20675655 22266823 22562137 23065650
PRKCD TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17906639 16314418 16377624
RPA3 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA2 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA1 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RNF40 RNF20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21362549 16307923 19410543
RNF20 RNF40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21362549 16307923 19410543
RPA2 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 UBE2B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA3 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 UBE2B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA2 RPA3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 UBE2B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
SP1 UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19733223 17409431 11872750
TAF1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 28673515 15053879 20124405 16713569 29556568 24289924
UBE2D1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215
RAD18 UBE2N â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
SHPRH SHPRH â—¼   KO_DOWN_REGULATES ✅ - -4.0 3.99 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
NBN NBN â—¼   KO_DOWN_REGULATES ✅ - -6.31 6.3 PKG 28854368