Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SMC1A BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11877377 5215162
CDK9 NCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
PCNA FEN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
E2F4 FEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
RPA1 FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592449
UBE2N HLTF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18719106 0805685105
HLTF UBE2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18316726 0800563105
E2F4 HLTF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 MSH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067 18319725
SHPRH UBE2V2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17108083
UBC UBE2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 5211616 10388568
EWSR1 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
USP7 CHFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17442268
E2F4 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15510213 18319725
E2F4 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12789259 18319725
SP3 TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9677424 9325332
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
ESR1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14695898 18252963
APLF CHD1L â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 1204073 5215931 11244506
SP3 SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15247906 11517158 10825178 16734381 9329821 12414801 12200149 23825960
BRCA1 ETAA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27723720 29656893
CHD1L HLTF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SHPRH HLTF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18719106 21396873
MPPA HLTF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ESR1 PGR â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
CHD1L APLF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 23926104 19661379
H2B1A APLF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
APLF HLTF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
BRCA1 RAD18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29656893 25184681 23901102
BRCA1 CDK9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22990118 28278048
RN146 CHD1L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 21799911 26186194
RN146 HLTF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21799911 26186194 21825151
H2B1A HLTF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
UBE2A UBE2B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 25582440
SPRTN UBC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
BRCA1 UBE2N â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CHD1L RNF146 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HLTF S100A10 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
RAD18 PCNA â—¼   UBIQUITINATION ✅ + 0.86 0.86 Signor 19706603
BRCA1 MSH2 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
PCNA UBC â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
SP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14710355 16713569 12706836 10720440 17766039
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
FEN1 MSH2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 RPA1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
SMC1A BRCA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11877377 25184681 16713569 26831064
BRCA1 UBE2N â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19712108 21965653 17873885
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HLTF RAD18 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
PARK2 UBE2N â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
E2F4 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21102443 16713569 9244350
RAD18 PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21227930 23345618 26170230 31160570 21858012 22904075 32701997 28924044 31887036 17720710 20600238 18363965 20064529 30700555 31873223 17108083 15359278 18245774 33508099 20675655 24958773 27377895 30563767 28831681 21967848
ESR1 SP3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10816575 16651265 31527615
HLTF UBE2V2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
ESR1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 1244506 11782371 15674350 29367421 27977889 17392432 16860316 10334989 16260778 11244506 16061635 12400015 17505062 20060929 25499220 16713569 31527615 11493692
BRCA1 MSH2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11498787 16713569 10783165 15886699 16260778
PCNA DTL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25154416 21725088 16861906 29424068 30301766 30623174 20129063
UBE2B HLTF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
PCNA HLTF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
HLTF UB2V2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18316726 30696947 22904075
PGR HLTF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18174357 12890680
HLTF PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18719106 26350214
SHPRH RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
UBE2N RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2V2 RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2N SHPRH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
UBE2B SHPRH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
UBE2N UBE2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2B UBE2V2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
E2F4 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17671431
E2F4 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17531812 12789259 20946668
SP1 TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9677424 9325332 8955122
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
SP3 UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19733223
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
MSH2 PCNA â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
PCNA MSH2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 15225546 12171929 16189514 8858149
HLTF UBE2N â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
HLTF PCNA â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 18719106 26350214 22904075 30696947 32701997 28924044 18316726 31973093
HLTF UBE2N â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 18719106 18316726 30696947 22904075
HLTF RAD18 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 18719106 23555860 21396873 25023518 18316726
FEN1 PCNA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 17115032 7673186 8876181 1477073 14657243 16216273 26030842 31467278 26496610 11430825 12853968 26751069 32900933 22592530 8668533 26264872 11313979 30184152 24958773 24728180 11601988 9545252 9178907 15616578 9305916 18692475 29997244 22556262 15576034 33961781 26186194 22606318
RAD18 UBE2A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 26170230 21858012 22904075 25023518 31887036 18363965 24672041 15509568 25582440 26496610 18926833 17108083 15359278 10884424 27377895 10908344 22456510 19549727 21967848 24981860
RAD18 UBE2B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 21422291 21858012 17720710 18363965 20064529 31873223 21549715 25582440 15359278 18245774 33508099 27569044 20675655 10884424 24958773 27377895 10908344 30367120 19549727 33961781
HLTF PCNA â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
DTL PCNA â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PCNA SPRTN â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
UBC USP7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
PCNA RAD18 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RAD18 UBE2A â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
UBC UBE2V2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
UBE2N UB2V2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16129784 25909880 14517261 15147900 18678647 11504715 12569095 33619271 12834344 26148049 32659264 16112642 21114314 22939629 11473244 17964296 12847084 16122702 31638574 19549727 11473255 16215985 27173435 33961781 15749714 26344197
PCNA RPA1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PARK2 UBC â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
FEN1 PCNA â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD18 UBE2B â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RAD18 UBC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
UBC UBE2N â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PCNA BRCA1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA BRCA1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
E2F4 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20133863 21701264 17531812 17001309 20818429 17106239 23108140
SP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15252835 17373631 18377656 19466541
E2F4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9244350 18319725 16713569 12909625
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
RPA1 DTL â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA DTL â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA1 FEN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
PCNA FEN1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
PCNA FEN1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
PCNA FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 28514442 15576034 8668533 3113402 11601988 12853968 31467278 1477073 24958773 7673186 16216273 11313979 15616578 8876181 14657243 11430825 26496610 16189514 9305916 22606318 28073635 19153658 26751069 26186194 9178907 22592530 24728180 17115032 18692475 26030842 16326861 29997244 22556262 9545252 31515488
SP1 FMR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10612627 16886907 9328468 15479157 15175277 16500891
PCNA MSH2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20154325 22118461 11274057 23840062
RPA1 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RAD18 PCNA â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10884424 15280666 15688063 16611994 16824193 17652783 18157158 18196958 18363965 18498753 19013543 19258535 19396164 20129063 20675655
RAD18 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18363965 19706603 17652783 18196958 18498753 20129063 21227930 10884424 19013543 18157158 15280666 19258535 16611994 19396164 20675655
RPA1 UBE2B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
SHPRH PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 19706603 17652783 18196958 19851286 16789823 18719106 18525240 18647995 18157158 10880451 19258535 16224103 20675655 16518696
UBE2A PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18363965 10884424 12820959 19459846 19258535 19440234 17652783 15147722 15169778 19706603 18498753 12226657 20129063 10722742 18006823 18157158 16611994 20675655 18196958 15340381 19013543 15280666 19396164 10721693
UBE2N PCNA â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10880451 16224103 16518696 17652783 18157158 18196958 18525240 18647995 19217833 19258535 19851286 20675655
UBE2N PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 18772547 12820959 18525240 19459846 19258535 19440234 17652783 15147722 10880451 15169778 19851286 10722742 18647995 18006823 18157158 16224103 20675655 16518696 18196958 15340381 10721693
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12554796 12706304 15019994 20087433 10894148
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19733223 17409431 11872750
ESR1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 12829318 12554765 12446585 11000528 15019994 8043503 23027806 9058379 9717846 18414489 12706304 10835496 16293641 18784357 12761896 8145766 22543272 15743834 8530508 10894148
PGR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 22396492 16168121 12612073 11000528 18988627 26153859