Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
LPP SHPRH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H3C2 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
INS CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28601906 25748795
NES EBF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FBXW7 SHPRH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FDFT1 SHPRH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPIB FLNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UBE2N HLTF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18719106 0805685105
HLTF UBE2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18316726 0800563105
UBE2A HSPA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA9 SHPRH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UBTF POLR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21289084 17878937
PPIB SHPRH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SHPRH UBE2V2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17108083
SHPRH TPM2 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
RAD18 CAV1 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
RAD18 PGM1 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
H31 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 24981860
SHPRH HLTF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21396873 18719106
RAD18 HSPA2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
SHPRH MSL3P1 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
UBE2A UBE2B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 25582440
CDC6 FBXW7 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
SHPRH NES â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
H31 PCNA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33029857 26527279
H4 SHPRH â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 31434570
SHPRH HSPA2 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
HIST1H3A HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
SHPRH RBMS2 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
HIST1H3A HIST1H4A â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
MLH1 PCNA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28439008 32814904 15225546
RAD18 PCNA â—¼   UBIQUITINATION ✅ + 0.86 0.86 Signor 19706603
H31 SHPRH â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 34079125 31434570 25281560 28400511
CAV1 INSR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31217420 10598578
SHPRH NRP2 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
H31 RBBP7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 25330109 29263092 20080577 19410544 29568061 26527279 16622419
HLTF RAD18 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
SHPRH P4HA2 â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
RAD18 PCNA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21967848 28924044 21227930 20675655 32701997 21858012 20064529 28831681 33508099 17108083 18363965 23345618 26170230 17720710 24958773 15359278 31873223 18245774 30700555 31887036 30563767 20600238 22904075 31160570 27377895
HLTF UBE2V2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
SHPRH SDC1 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
RAD18 DTL â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
SHPRH RBM3 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
PCNA HLTF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
PCNA DTL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16861906 25154416 21725088 30301766 30623174 29424068 20129063
HLTF PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18719106 26350214
H4 RBBP7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9427644 18571423 30804502 20953179 19862764 28514442 29104064
ANXA1 UBE2D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UBE2B HLTF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
SHPRH RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
UBE2N RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2V2 RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2N SHPRH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
UBE2B SHPRH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
UBE2N UBE2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2B UBE2V2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
RAD18 SDC1 â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
SHPRH EPHA1 â—¼   KO_DOWN_REGULATES ✅ - -0.92 0.91 PKG 28854368
SHPRH INA â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
SHPRH KNSTRN â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
SHPRH NODAL â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
HLTF UBE2N â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
SHPRH GPC4 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
RAD18 MT1E â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
SHPRH SLC16A3 â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
HLTF PCNA â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
DTL PCNA â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
INS INSR â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SHPRH CDC6 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
PCNA RAD18 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RAD18 USP1 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
RAD18 UBE2A â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RAD18 NRK â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
H31 H4 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 18571423 19498464 14578449 30804502 16622419 19766566 20498094 20739937 25533843 20080577 26527279 8598932 22828868 27248496 28514442 25416956 21724829 34079125 29568061 14718166 23319141 19410544
RAD18 UBE2B â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PCNA MLH1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20154325 22118461 11274057 23840062
PCNA POLK â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11900249 12466554 12648680 12930902 14624239 14657033 14726013 15189446 15189466 15459660 15703371 16697054 17035102 17116885 17296725 17582221 17652783 17884153 18087292 18157158 18196958 18584027 18677104 18809224 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22266823 22743550 23065650 23414611 24050180 8264637 8978692
PCNA POLK â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11900249 12466554 12648680 12930902 14624239 14657033 14726013 15189446 15189466 15459660 15703371 16697054 17035102 17116885 17296725 17582221 17652783 17884153 18087292 18157158 18196958 18584027 18677104 18809224 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22266823 22743550 23065650 23414611 24050180 8264637 8978692
UBE2N PCNA â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10880451 16224103 16518696 17652783 18157158 18196958 18525240 18647995 19217833 19258535 19851286 20675655
USP1 PCNA â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
RAD18 PCNA â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10884424 15280666 15688063 16611994 16824193 17652783 18157158 18196958 18363965 18498753 19013543 19258535 19396164 20129063 20675655
UBE2N PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 18772547 12820959 18525240 19459846 19258535 19440234 17652783 15147722 10880451 15169778 19851286 10722742 18647995 18006823 18157158 16224103 20675655 16518696 18196958 15340381 10721693
RAD18 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18363965 19706603 17652783 18196958 18498753 20129063 21227930 10884424 19013543 18157158 15280666 19258535 16611994 19396164 20675655
SHPRH PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 19706603 17652783 18196958 19851286 16789823 18719106 18525240 18647995 18157158 10880451 19258535 16224103 20675655 16518696
UBE2A PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18363965 10884424 12820959 19459846 19258535 19440234 17652783 15147722 15169778 19706603 18498753 12226657 20129063 10722742 18006823 18157158 16611994 20675655 18196958 15340381 19013543 15280666 19396164 10721693
USP1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 19264559 35324534 19686080 18082604 23589330 20353596 19622404 19075014 16531995 18082605 19217432 18931676 33619839
H3C2 AGO2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16936726 22722852 25313066 16373483 21589992 24086155 17085592 22445173 18227514 18852463 21427083 22961379 24388755 22064859
INSR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9756945 10598578 12036959 17699617
INS INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8393875 21743783 21317886 24296476 26374090 29069585 26245346 16956584 19902173 20332342 23363978 23331499 18988627 23302862 22832498 2550426 15870194 11278498 19752148 29512653 23304064 24633815 17227660 22521887 23223021 30197476
SHPRH EBF2 â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
RAD18 UBE2N â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
SHPRH ESYT2 â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
RAD18 EPHA1 â—¼   KO_DOWN_REGULATES ✅ - -1.03 1.02 PKG 28854368
RAD18 FDFT1 â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
SHPRH FLNC â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
SHPRH NEXN â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
SHPRH PGM1 â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
SHPRH CYP27A1 â—¼   KO_UP_REGULATES ✅ + 1.07 1.07 PKG 28854368
SHPRH INSR â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
SHPRH IGFBP2 â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
SHPRH VIM â—¼   KO_DOWN_REGULATES ✅ - -1.12 1.11 PKG 28854368
RAD18 ESYT2 â—¼   KO_UP_REGULATES ✅ + 1.13 1.13 PKG 28854368
RAD18 FLNC â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
SHPRH ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
RAD18 IGFBP2 â—¼   KO_UP_REGULATES ✅ + 1.2 1.2 PKG 28854368
SHPRH MT1F â—¼   KO_DOWN_REGULATES ✅ - -1.23 1.22 PKG 28854368
SHPRH GALC â—¼   KO_UP_REGULATES ✅ + 1.23 1.23 PKG 28854368
RAD18 INA â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
SHPRH NRK â—¼   KO_DOWN_REGULATES ✅ - -1.31 1.31 PKG 28854368
RAD18 SLC16A3 â—¼   KO_UP_REGULATES ✅ + 1.31 1.31 PKG 28854368
RAD18 TAGLN â—¼   KO_DOWN_REGULATES ✅ - -1.33 1.32 PKG 28854368
SHPRH FN1 â—¼   KO_UP_REGULATES ✅ + 1.34 1.34 PKG 28854368
SHPRH TCEAL8 â—¼   KO_DOWN_REGULATES ✅ - -1.37 1.36 PKG 28854368
SHPRH CAV1 â—¼   KO_DOWN_REGULATES ✅ - -1.43 1.42 PKG 28854368
SHPRH MT1G â—¼   KO_DOWN_REGULATES ✅ - -1.5 1.49 PKG 28854368
RAD18 GPC4 â—¼   KO_DOWN_REGULATES ✅ - -1.57 1.56 PKG 28854368
RAD18 MT1F â—¼   KO_UP_REGULATES ✅ + 1.59 1.59 PKG 28854368
SHPRH PGK2 â—¼   KO_UP_REGULATES ✅ + 1.62 1.62 PKG 28854368
SHPRH LHPP â—¼   KO_UP_REGULATES ✅ + 1.74 1.74 PKG 28854368
SHPRH MT1H â—¼   KO_DOWN_REGULATES ✅ - -1.89 1.88 PKG 28854368
RAD18 VIM â—¼   KO_DOWN_REGULATES ✅ - -1.95 1.94 PKG 28854368
SHPRH ANXA3 â—¼   KO_DOWN_REGULATES ✅ - -2.13 2.12 PKG 28854368
RAD18 NES â—¼   KO_DOWN_REGULATES ✅ - -2.16 2.15 PKG 28854368
RAD18 LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -2.21 2.2 PKG 28854368
RAD18 CDC6 â—¼   KO_DOWN_REGULATES ✅ - -2.52 2.51 PKG 28854368
SHPRH LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -2.54 2.53 PKG 28854368
SHPRH MT1E â—¼   KO_DOWN_REGULATES ✅ - -2.59 2.58 PKG 28854368
SHPRH TAGLN â—¼   KO_DOWN_REGULATES ✅ - -2.6 2.59 PKG 28854368
RAD18 ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -3.21 3.2 PKG 28854368
SHPRH INS â—¼   KO_DOWN_REGULATES ✅ - -3.7 3.69 PKG 28854368
SHPRH SHPRH â—¼   KO_DOWN_REGULATES ✅ - -4.0 3.99 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368