Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
XPC ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16849332
XPC PARP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DDB2 XPC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
SHPRH RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
POLB MT1E â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
UNG MT1E â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
RAD18 MT1E â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
PARP2 POLB â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
PARP2 POLB â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
ATM SMARCAL1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM PARP2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM SMARCAL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19841479 15964794 11877377 17303408 16163361 23847781 19793861 21558276 12607003 15459660
DDB2 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15882621 22039351 19740755 29604309 23319653
TDG XPC â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 16713580 17129768 17855402 17884153 18199748 18543256 19809470 19847258 20211143
TDG XPC â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 16713580 17129768 17855402 17884153 18199748 18543256 19809470 19847258 20211143
UVSSA MT1E â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
XPC MT1E â—¼   KO_UP_REGULATES ✅ + 1.19 1.19 PKG 28854368
POLE3 MT1E â—¼   KO_UP_REGULATES ✅ + 1.21 1.21 PKG 28854368
PARP2 MT1E â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
RECQL5 MT1E â—¼   KO_UP_REGULATES ✅ + 1.62 1.62 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
MUS81 MT1E â—¼   KO_UP_REGULATES ✅ + 2.44 2.44 PKG 28854368
PAXX MT1E â—¼   KO_DOWN_REGULATES ✅ - -2.54 2.53 PKG 28854368
SMARCAL1 MT1E â—¼   KO_UP_REGULATES ✅ + 2.57 2.57 PKG 28854368
SHPRH MT1E â—¼   KO_DOWN_REGULATES ✅ - -2.59 2.58 PKG 28854368
POLE3 POLE3 â—¼   KO_DOWN_REGULATES ✅ - -2.96 2.95 PKG 28854368
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
TDG MT1E â—¼   KO_UP_REGULATES ✅ + 3.35 3.35 PKG 28854368
ATM MT1E â—¼   KO_DOWN_REGULATES ✅ - -3.51 3.5 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
SHPRH SHPRH â—¼   KO_DOWN_REGULATES ✅ - -4.0 3.99 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
TREX1 MT1E â—¼   KO_UP_REGULATES ✅ + 5.24 5.24 PKG 28854368
UNG UNG â—¼   KO_DOWN_REGULATES ✅ - -5.41 5.4 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
DDB2 MT1E â—¼   KO_DOWN_REGULATES ✅ - -6.27 6.26 PKG 28854368
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368
RECQL5 RECQL5 â—¼   KO_DOWN_REGULATES ✅ - -7.08 7.07 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368
SMARCAL1 SMARCAL1 â—¼   KO_DOWN_REGULATES ✅ - -7.33 7.32 PKG 28854368