Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
USP7 UVSSA â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ERCC3 KPNA3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
UVSSA EFHD2 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
ERCC6 ERCC8 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ERCC8 DDB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12732143 22232169 26826127 29531219 17392787 16751180 16949367 31970402 28416769 22902626
ERCC6 DDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
ERCC2 POLR2A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC6 POLR2A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
GTF2H1 POLR2A â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
UVSSA LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
UVSSA MAN1C1 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
ERCC3 POLR2A â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ERCC3 ERCC2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15220921 27193682 16669699 33381997 22939629 26340423 8152490 8652557 9118947 22678362 19934020
DDB1 ERCC8 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CDK7 POLR2A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDK7 ERCC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ERCC3 GTF2H1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDK7 GTF2H1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDK7 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ERCC2 GTF2H1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ERCC2 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDK7 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18079403 27197304 26799765 10886368 14662762 16327805 24662513 26748711 25561469 21331744 19667075 18079404 22137580 9130709 20457598 19901026 19450536 20932174
GTF2H1 ERCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9130708 8652557 10734072
ERCC2 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10734072 8652557 10024882 16669699
GTF2H1 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10403766 10734072 9173976 8194528 15220921 9118947 9130708 8652557 11259578 26340423 17643375
ERCC8 ERCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22902626 16751180 7664335 20541997 16916636 26826127 22032989
UVSSA USP7 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
UVSSA NODAL â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
UVSSA RHBDF1 â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
UVSSA CYR61 â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
UVSSA MT1E â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
UVSSA EBF2 â—¼   KO_DOWN_REGULATES ✅ - -1.06 1.05 PKG 28854368
UVSSA UAP1L1 â—¼   KO_DOWN_REGULATES ✅ - -1.2 1.19 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
UVSSA INS â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
UVSSA SERPINB9 â—¼   KO_DOWN_REGULATES ✅ - -1.36 1.35 PKG 28854368
UVSSA RPL22L1 â—¼   KO_DOWN_REGULATES ✅ - -1.39 1.38 PKG 28854368
UVSSA RPS4Y1 â—¼   KO_DOWN_REGULATES ✅ - -4.53 4.52 PKG 28854368