Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RECQL4 POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19567405
TP53 RECQL4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15674334
ACVR2B ACVR1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16446785
XPC ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16849332
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
TP53 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10749849 16713569
POU5F1 LEFTY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16954384 17068183
ATM EXO1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 20019063
XPC PARP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ATM NBN â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 10802669
TGFB2 TGFB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11157754 33961781 27684187 11483955
XPC XPA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17154534 12486030
NHEJ1 TDG â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
ACVR2B BMP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
DDB2 XPC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ACVR2A ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12682303 9032295 8612709
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
SHPRH RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
EXO1 LEFTY1 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
ATM NBN â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
XPC NODAL â—¼   KO_UP_REGULATES ✅ + 0.93 0.93 PKG 28854368
SHPRH NODAL â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
ACVR2A BMP7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
CBX1 LEFTY1 â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
ATM NODAL â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
ACVR2A BMP2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UVSSA LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
POU5F1 SOX2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
TDG LEFTY1 â—¼   KO_UP_REGULATES ✅ + 0.99 0.99 PKG 28854368
PARP2 POLB â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
PARP2 POLB â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
GDF1 ACVR1B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
ACVR2B ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 23180781 8622651 16446785 12364468 18988627
TDGF1 ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19874624 11909953
NODAL ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19874624 11952836
ACVR1C NODAL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
NODAL ACVR1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12606401 15531507
GDF1 ACVR1C â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
ACVR2A GDF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
BMP2 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17483092 10880444 21702718 17295905 25938661 20959140
BMP6 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10504300
GDF5 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8702914
BMP7 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9748228 7790373 12667445
NODAL ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11952836
TDGF1 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12682303
GDF7 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16049014
GDF1 ACVR2B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
BMP7 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9748228 23331499 16446785
NODAL ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 16446785 11952836
GDF5 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 8702914 16446785
LEFTY2 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11952836
BMP2 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 20385559 16446785 28977600 15064755 18988627 17295905
BMP6 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 21071413 16446785 10504300
ATM PARP2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM EXO1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 12433983 12861053 17485521 23146902 10839545 19413330 15302935 27602502 17429352 19523210 24360018 20068231 17507690 17570479 10608806 12598907 18669648 25088203 18003706 11252893 17431132 23097684 10766245 12814430 10802669 21664921 26512707 10839544 11927276 21130714 17525332 12447395 14707289 15733840 15279770 25119968 18644472 28822740
ATM EXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 15964794 11877377 17303408 18756267 16163361 15867354 23847781 23675572 25956864 26240375 11438669 24705021 12607003 18048416 17525332 20019063 15459660
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
CFC1 GDF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
CFC1 NODAL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
XPA DDB2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
DDB2 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15882621 22039351 19740755 29604309 23319653
NBN EXO1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TDGF1 GDF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
KLF4 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18511453 16244670 17308127 21132436 17659301
TDGF1 NODAL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
POU5F1 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20505756 12136102 17324942 15988017 17068183
POU5F1 TDGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16846370 20549704 21083502 17068183
TDG XPC â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 16713580 17129768 17855402 17884153 18199748 18543256 19809470 19847258 20211143
TDG XPC â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 16713580 17129768 17855402 17884153 18199748 18543256 19809470 19847258 20211143
TP53 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12732139 10618379 22264233 23706820 14514686 8183578 14761612 16138117 18593586 23063463 8119773
TP53 XPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12771027 22336944 12242345 23050045 16357511 12967652 15927209
TP53 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12771027 9346961 10779360 21340684 19004803 10367887 20066118 12496474 12242345 20457558 20182602 10962562 6396087 9892649 12967652
UVSSA NODAL â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
NHEJ1 LEFTY1 â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
RECQL4 GDF3 â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
MUS81 LEFTY1 â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
RECQL5 LEFTY1 â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
NBN LEFTY1 â—¼   KO_UP_REGULATES ✅ + 1.08 1.08 PKG 28854368
XPC LEFTY1 â—¼   KO_UP_REGULATES ✅ + 1.08 1.08 PKG 28854368
NHEJ1 NODAL â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
DDB2 NODAL â—¼   KO_DOWN_REGULATES ✅ - -1.17 1.16 PKG 28854368
DDB2 TCF3 â—¼   KO_DOWN_REGULATES ✅ - -1.29 1.28 PKG 28854368
SETX NODAL â—¼   KO_DOWN_REGULATES ✅ - -1.41 1.4 PKG 28854368
PAXX LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -1.44 1.43 PKG 28854368
TREX1 LEFTY1 â—¼   KO_UP_REGULATES ✅ + 1.48 1.48 PKG 28854368
SETX LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -1.61 1.6 PKG 28854368
TP53 NODAL â—¼   KO_DOWN_REGULATES ✅ - -1.64 1.63 PKG 28854368
RECQL4 NODAL â—¼   KO_DOWN_REGULATES ✅ - -1.64 1.63 PKG 28854368
RECQL4 LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -1.71 1.71 PKG 28854368
POLB LEFTY1 â—¼   KO_UP_REGULATES ✅ + 1.88 1.88 PKG 28854368
XPA LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -1.91 1.9 PKG 28854368
DDB2 LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -1.97 1.96 PKG 28854368
RAD18 LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -2.21 2.2 PKG 28854368
PARP2 LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.24 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
TP53 LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -2.28 2.27 PKG 28854368
SHPRH LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -2.54 2.53 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
ATM LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -2.78 2.77 PKG 28854368
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
TP53 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -3.51 3.5 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
SHPRH SHPRH â—¼   KO_DOWN_REGULATES ✅ - -4.0 3.99 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
NBN NBN â—¼   KO_DOWN_REGULATES ✅ - -6.31 6.3 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368
RECQL5 RECQL5 â—¼   KO_DOWN_REGULATES ✅ - -7.08 7.07 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368
SETX SETX â—¼   KO_DOWN_REGULATES ✅ - -8.56 8.55 PKG 28854368