Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
DCLRE1C XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16857680
B2M RAB9A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
OPTN PAXX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PAXX XRCC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1261971 25574025
NHEJ1 XRCC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
OPTN SLC2A13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PAXX BRAT1 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
XRCC4 NDUFA4 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
XRCC4 CDCA7 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
MT-CO2 NDUFA4 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
NHEJ1 SLC2A13 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
PAXX PYGL â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
PAXX POLG2 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
PAXX HYPK â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
PAXX INA â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
XRCC4 PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9430729 15194694 22939629 9259561 15520013
PAXX CDCA7 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
PAXX TWSG1 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
PAXX RPS27L â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
XRCC4 RRM2 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
PRKDC XRCC4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
LIG4 XRCC6 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
LIG4 NHEJ1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
DCLRE1C PRKDC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PAXX CALB2 â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
PAXX CENPE â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
PAXX NCBP2-AS2 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
PAXX RRM2 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
XRCC5 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26496610 22404984 15520013 21679440 26446488 26344197 17308091 15941674 28154079 16857680 20711232 19303849 20023628 15758953 20085707 10750018 10446239 33005030 9312071 28345663 12393188
XRCC6 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8422676 20711232 19303849 26175416 28345663 30585729 17308091 22939629 26496610 10750018 15941674 33005030 21969602 15520013 10064605 21575865 26446488
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 22939629 15367688 26496610 26774286 21172662 11196700 15520013 22863883 21679440 17159921 30021884 14681455 26446488 26344197 10207052 30585729 17308091 11493912 10757784 10219089 10984620 19118032 12145306 32296183 28035050 19177010 18809223 21454661 15910003 10783163 28514442 21070772 25574025 15023334 7699019 10750018 10446239 22451927 33005030 9488450 17283121 19906305
PAXX HDHD5 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
PAXX FBP1 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
PAXX IGFBP2 â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
XRCC4 STX16 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
XRCC4 ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
XRCC5 XRCC6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
NHEJ1 HDHD5 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
NHEJ1 XRCC5 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
PAXX GLUL â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
XRCC4 TWSG1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
PAXX SLC2A13 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
NHEJ1 PYGL â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
PAXX GCAT â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
XRCC4 CRAT â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
XRCC4 PYGL â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PAXX NDUFB9 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
NHEJ1 TWSG1 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PAXX UBE2H â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
PAXX PGK1 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
PAXX CRAT â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
XRCC4 ICAM1 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LIG4 XRCC4 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 11163244 12032095 12471202 15385968 15703371 16439205 16697054 17088286 17638872 18077224 19346677 19473888 19546231 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
LIG4 XRCC4 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 11163244 12032095 12471202 15385968 15703371 16439205 16697054 17088286 17638872 18077224 19346677 19473888 19546231 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
PRKDC LIG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15194694 15941674 17570479
XRCC4 DCLRE1C â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
XRCC5 DCLRE1C â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11955432 16600297 16093244 16914548
XRCC6 DCLRE1C â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11955432 16600297 16093244 16914548
DCLRE1C NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC DCLRE1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17242184 15723659 11955432 16600297 23163657 22529269 16874298 21641068 19423708 15936993 1660029
GLUL PYGL â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
GLUL PYGL â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
GLUL PYGL â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
NDUFB9 NDUFA4 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFA4 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
XRCC5 NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC6 NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
STX16 RAB9A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 18195106 25343031 16885419 19620288 18946081 17488291 8440258
PAXX PPIC â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
NHEJ1 LEFTY1 â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
PAXX ECHDC3 â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
NHEJ1 CD81 â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
PAXX SKP2 â—¼   KO_DOWN_REGULATES ✅ - -1.03 1.02 PKG 28854368
XRCC4 HMOX1 â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
XRCC4 GLUL â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
PAXX SCRN2 â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
PAXX STX16 â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
PAXX METTL25 â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
XRCC4 HMGCS1 â—¼   KO_UP_REGULATES ✅ + 1.05 1.05 PKG 28854368
PAXX HMGCS1 â—¼   KO_DOWN_REGULATES ✅ - -1.07 1.06 PKG 28854368
NHEJ1 NIPSNAP1 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
PAXX RAB9A â—¼   KO_UP_REGULATES ✅ + 1.09 1.09 PKG 28854368
PAXX PDCD4 â—¼   KO_UP_REGULATES ✅ + 1.09 1.09 PKG 28854368
NHEJ1 NDUFA4 â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
NHEJ1 PDCD4 â—¼   KO_DOWN_REGULATES ✅ - -1.11 1.1 PKG 28854368
PAXX CRELD2 â—¼   KO_DOWN_REGULATES ✅ - -1.12 1.11 PKG 28854368
NHEJ1 SCRN2 â—¼   KO_DOWN_REGULATES ✅ - -1.12 1.11 PKG 28854368
PAXX IQGAP3 â—¼   KO_DOWN_REGULATES ✅ - -1.13 1.12 PKG 28854368
PAXX FEZ2 â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
PAXX RPL22L1 â—¼   KO_DOWN_REGULATES ✅ - -1.14 1.13 PKG 28854368
PRKDC RPL22L1 â—¼   KO_UP_REGULATES ✅ + 1.15 1.15 PKG 28854368
PAXX CAT â—¼   KO_DOWN_REGULATES ✅ - -1.17 1.16 PKG 28854368
XRCC4 RPL22L1 â—¼   KO_UP_REGULATES ✅ + 1.17 1.17 PKG 28854368
NHEJ1 ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
NHEJ1 GCAT â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
PAXX CTSB â—¼   KO_UP_REGULATES ✅ + 1.26 1.26 PKG 28854368
PAXX TAGLN â—¼   KO_DOWN_REGULATES ✅ - -1.36 1.35 PKG 28854368
PAXX MT-CO2 â—¼   KO_DOWN_REGULATES ✅ - -1.38 1.37 PKG 28854368
PAXX ICAM1 â—¼   KO_UP_REGULATES ✅ + 1.37 1.37 PKG 28854368
PAXX FAM162A â—¼   KO_UP_REGULATES ✅ + 1.42 1.42 PKG 28854368
PAXX LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -1.44 1.43 PKG 28854368
PAXX SPP1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368
XRCC4 SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.51 1.5 PKG 28854368
XRCC4 LIG4 â—¼   KO_DOWN_REGULATES ✅ - -1.52 1.51 PKG 28854368
PAXX PSMD5 â—¼   KO_DOWN_REGULATES ✅ - -1.56 1.55 PKG 28854368
XRCC4 PDCD4 â—¼   KO_DOWN_REGULATES ✅ - -1.6 1.59 PKG 28854368
NHEJ1 SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.62 1.61 PKG 28854368
PAXX B2M â—¼   KO_UP_REGULATES ✅ + 1.62 1.62 PKG 28854368
NHEJ1 TAGLN â—¼   KO_UP_REGULATES ✅ + 1.62 1.62 PKG 28854368
PAXX NIPSNAP1 â—¼   KO_UP_REGULATES ✅ + 1.82 1.82 PKG 28854368
PAXX HMOX1 â—¼   KO_DOWN_REGULATES ✅ - -1.84 1.83 PKG 28854368
NHEJ1 CALB2 â—¼   KO_DOWN_REGULATES ✅ - -1.86 1.85 PKG 28854368
NHEJ1 HMOX1 â—¼   KO_UP_REGULATES ✅ + 1.85 1.85 PKG 28854368
NHEJ1 SPP1 â—¼   KO_UP_REGULATES ✅ + 2.25 2.25 PKG 28854368
PAXX SLC16A3 â—¼   KO_UP_REGULATES ✅ + 2.28 2.28 PKG 28854368
PAXX MT1X â—¼   KO_DOWN_REGULATES ✅ - -2.31 2.3 PKG 28854368
PAXX MT1E â—¼   KO_DOWN_REGULATES ✅ - -2.54 2.53 PKG 28854368
PAXX NDUFA4 â—¼   KO_DOWN_REGULATES ✅ - -2.58 2.57 PKG 28854368
PAXX MT1G â—¼   KO_DOWN_REGULATES ✅ - -2.92 2.91 PKG 28854368
NHEJ1 CRAT â—¼   KO_DOWN_REGULATES ✅ - -3.19 3.18 PKG 28854368
XRCC4 SPP1 â—¼   KO_UP_REGULATES ✅ + 3.34 3.34 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
PAXX RPS4Y1 â—¼   KO_DOWN_REGULATES ✅ - -7.13 7.12 PKG 28854368