Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FOXA2 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10674400 9685261
SREBF2 HMGCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12177166 23709690
SREBF1 HMGCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9651391
NFYA HMGCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7665553
SREBF2 HNF4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12855700 5216527
MDC1 HMGCS1 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
POLE3 HMGCS1 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
DDB2 SDC1 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
HDAC1 ERCC6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31722399 26496610 26030138
CREBBP TDG â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RAD18 SDC1 â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
TREX1 HMGCS1 â—¼   KO_UP_REGULATES ✅ + 0.99 0.99 PKG 28854368
TDG CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11864601 17129768 24748645
CREBBP SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9651391 16799563 10235267 9765204 8918891
HDAC1 SERPINB5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18247378 23770133 10709100
NFYA SREBF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 12177166 18559965 9748295 18654640 8798690 20450493
NFYA SREBF2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 12177166 18559965 9748295 18654640 8798690 20450493
SREBF1 SREBF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14702347 16282353 9786926 11278785
XRCC4 HMGCS1 â—¼   KO_UP_REGULATES ✅ + 1.05 1.05 PKG 28854368
ERCC6 HMGCS1 â—¼   KO_UP_REGULATES ✅ + 1.05 1.05 PKG 28854368
PAXX HMGCS1 â—¼   KO_DOWN_REGULATES ✅ - -1.07 1.06 PKG 28854368
MUS81 HMGCS1 â—¼   KO_UP_REGULATES ✅ + 1.14 1.14 PKG 28854368
FAN1 HMGCS1 â—¼   KO_DOWN_REGULATES ✅ - -1.17 1.16 PKG 28854368
RECQL4 HMGCS1 â—¼   KO_DOWN_REGULATES ✅ - -1.22 1.22 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
RECQL4 SDC1 â—¼   KO_DOWN_REGULATES ✅ - -1.25 1.24 PKG 28854368
TDG HMGCS1 â—¼   KO_UP_REGULATES ✅ + 1.25 1.25 PKG 28854368
XRCC4 TDG â—¼   KO_UP_REGULATES ✅ + 1.27 1.27 PKG 28854368
DDB2 HMGCS1 â—¼   KO_DOWN_REGULATES ✅ - -1.75 1.75 PKG 28854368
RAD18 HMGCS1 â—¼   KO_DOWN_REGULATES ✅ - -1.84 1.83 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
POLE3 POLE3 â—¼   KO_DOWN_REGULATES ✅ - -2.96 2.95 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368