Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TDG DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17175537
DNMT3A TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17175537
TWSG1 KLK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLK6 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12928483
TDG SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PAXX TWSG1 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
NHEJ1 TDG â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
TWSG1 CHRD â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 11260715 16713569
TWSG1 BMP4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28514442 11260715
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
XRCC4 TWSG1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NHEJ1 TWSG1 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
TDG TWSG1 â—¼   KO_UP_REGULATES ✅ + 1.18 1.18 PKG 28854368
XRCC4 TDG â—¼   KO_UP_REGULATES ✅ + 1.27 1.27 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368