Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MBD3 POU5F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
OTX1 MDFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MYC CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21925595 23722468
H3F3A H3F3B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
H3F3B H3F3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3C HIST2H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3A HIST2H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3D HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3G HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3H HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3F HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3I HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3J â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3G HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3F HIST1H3H â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3H HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3D HIST1H3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H3C HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3E HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3G HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3F HIST1H3I â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3F HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3C HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3G â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3B HIST1H3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H3A HIST1H3B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
WFS1 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RRP8 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H3C2 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11242053 5213683
EED H3C2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 SUZ12 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
MYC H2BC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
RRP8 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
PRMT5 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1209814109 23071334
SUV39H1 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H4C6 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16628214 5218530
H4C6 DNMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
H4C6 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
H4C6 CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EED H4C6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4C6 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4C6 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4C6 SUZ12 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4C6 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4C6 PRMT5 â—¼   METHYLATION ✅ 2.0 0.8 intact 1209814109 23071334
HDAC1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10220385
GFAP H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUV39H1 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
RRP8 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
RBBP4 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
RBBP7 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EZH2 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EED H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
SUZ12 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
DNMT1 ASCL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15390277 16371653
EZH2 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23624935 21406404
MYC CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDH1 CCND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0913813107 20439707
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
POU5F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25128069 23433354
CREM CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22488648 17185632
EZH2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132185 21697275
EHMT1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19010785
RASSF1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12024041
CDC73 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18987311
CDH1 EPCAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DNMT3A CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16887905 18974268
SPI1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22472882 19423615
RB1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671466 14527674
STAT5A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15003515 21038417
TRIM28 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942393
SMARCA4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414052
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
RARB CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11786399 21868513
EZH2 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20574448
EZH2 CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20574448
FOXP3 CREM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20554955 17372992
USP7 DAXX â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 6799761 18566590
RASSF1 DAXX â—¼   COLOCALIZATION 2.0 0.8 intact 18566590 6799761
SUV39H1 DCAF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
DCAF8 MDFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DNMT1 RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21868513 14528273
DNMT1 RRP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17172825 18049164
DNMT1 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17172825 17584191
WFS1 DNMT3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DNMT3B DNMT3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20426865 15362956
STAT5A DNMT3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26059451
DNMT3A POU5F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21608077 22867868
DNMT3A DPP6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23409053
DNMT3A DNMT3L â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18544626 17965599
MYC DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15616584 19786833
TDG DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17175537
DNMT3A TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17175537
UBE2I DNMT3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18762900 11735126
DNMT3B RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20426865 18798999
DNMT3B JUP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16887905 17998942
DNMT3B SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16371653 17584191
DNMT3B WIF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23939044 16501252
DNMT3B DPP6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23409053
DNMT3B EHMT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16371653 17584191
ESR1 WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9259323 8625613
ESR1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
EZH2 HOXA9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20565746
EZH2 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18980680 17584191
STAT5A FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17182565 24298014
WFS1 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PDLIM7 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
H3F3A H3F3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HDAC1 MYCN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
RB1 HDAC1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
HIST2H3A HIST2H3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MYC HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17881904 18544564
HOXA9 RASSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17029216 17968314
PRMT5 HOXA9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22269951
SETDB1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MBD4 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
WFS1 KEAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF4 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20629177 22723415
MBD4 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
WT1 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23042785 18829110
STAT4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10702306
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
MYC TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9988278
WT1 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10470095
MYOG SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17194702 23609547
SUMO1 NRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18211901
PAF1 SUV39H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19906718
PDLIM7 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PIAS1 WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUV39H1 RASSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
RASSF1 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8009708 20069457
SPI1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14559995 12588990
RB1 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8434021
SPI1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17967894 7988559
TDG SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218717 16763556
WFS1 TDG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TFAP2A TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19701232 18754863
TET2 WT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25601757
TFAP2A TIMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8810321
UBE2I TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18082607
WT1 UBE2I â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8798754
DNMT3L HIST1H3J â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3H â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3D â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3E â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3I â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3F â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3G â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3B â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L H3F3A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST2H3A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST2H3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST1H3A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L H3F3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DNMT3L HIST3H3 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EED SUZ12 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HIST1H3J HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3H HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3D HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3E HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3I HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3F HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3G HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3C HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3B HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
SUMO1 CBX4 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24654937 33961781 20098713 22467880
DDB1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24249678 26679995 25189618 34026424
SP100 SUMO1 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
H3F3C UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST1H3E UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST2H3C UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST1H3B UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
H3F3B UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST1H3G UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST1H3C UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST2H3A UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
H3F3A UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST2H3PS2 UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST1H3I UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST1H3H UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST1H3D UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST1H3F UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST1H3A HIST1H3F â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
DNMT3A DNMT3B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
DDB1 MBD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 34026424
MBD3 MYC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24048479 30415952
BRCA1 KDM1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22990118 26831064
MYC CBX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CBX1 RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX1 EHMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
DNMT1 CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12867029 17470536
DAXX CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 24981860
CBX5 EHMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20562864 24981860
CBX5 SUZ12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27634302 20562864
CDC73 MYC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 26687678
CUL4B RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23238014 34026424
ESR2 DDB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 29509190
EED DDB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23238014 17041588
MYC DNMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
EZH2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27634302 26496610
ESR1 SUZ12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 26389696
ESR1 KLF4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
MYCN HDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18003922 31856871
MYC RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC TDG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 26496610
H3F3B SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST2H3D SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DDB1 HIST1H3J â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST1H3J SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DDB1 HIST1H3H â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST1H3H SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DDB1 HIST1H3D â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST1H3D SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST2H3PS2 SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DDB1 HIST1H3E â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST1H3E SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DDB1 HIST1H3I â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST1H3I SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DDB1 HIST1H3F â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST1H3F SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DDB1 HIST1H3G â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST1H3G SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DDB1 HIST1H3C â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST1H3C SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DDB1 HIST1H3B â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST1H3B SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DAXX H3F3A â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
H3F3A SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
H3F3C SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST1H3A SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST2H3A SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST2H3C SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST3H3 SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DNMT3A H3F3A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
DNMT3A H3F3C â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
DNMT3A HIST1H3H â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3D â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3E â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3I â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3F â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3G â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3C â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST1H3B â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DNMT3A HIST3H3 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
H3F3B SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3H SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3D SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3PS2 SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3E SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3I SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3F SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3G SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3C SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3B SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
H3F3A SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
H3F3C SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3A SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3C SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
CBX1 EHMT2 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
DNMT3B HIST1H3J â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3H â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3D â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3E â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3I â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3F â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3G â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3C â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST1H3B â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
DNMT3B HIST3H3 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CBX1 H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16415788 5218238
H3C2 CBX1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16415788 5218238
CBX5 EHMT2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HDAC1 EHMT1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
ESR1 KDM1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17289570 23403292 31527615
KDM1A EZH2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31130994 23455924
PIAS2 STAT4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12716907 16189514
CBX5 HIST1H3H â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST1H3D â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST1H3E â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST1H3I â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST1H3F â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST1H3G â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST1H3C â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 H3F3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 H3F3C â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST2H3C â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST2H3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
DNMT3B HIST2H3D â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3A HIST2H3D â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3B HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3A HIST2H3A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3A HIST2H3C â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3B HIST2H3A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3B HIST2H3C â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
HDAC1 UHRF1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CBX5 DNMT3B â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
PTGES3 TERT â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DDB1 HIST1H3A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CBX1 SUV39H1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
BRCA1 EZH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23624935 25531315
EZH2 DDB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27634302 23238014
SUZ12 DDB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27634302 23238014
DNMT3B EZH2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ESR1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21984853 31527615
ESR1 EZH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
ESR1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15961505 31527615
EZH2 MYCN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23362253 27728805
MYC TERT â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28205554 28628118 32140074
H3F3B MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H3D MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3H MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3D MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H3PS2 MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3E MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3I MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3F MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3G MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3C MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3B MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
H3F3A MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
H3F3C MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H3A MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H3C MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST3H3 MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CBX1 HIST2H3D â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 HIST1H3H â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 HIST1H3D â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 HIST1H3E â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 HIST1H3I â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 HIST1H3F â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 HIST1H3G â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 HIST1H3C â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 H3F3C â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 HIST2H3A â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 HIST2H3C â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 H3F3A â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
DAXX HDAC1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
H3F3A SMARCA4 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
HIST1H3J UHRF1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
HIST1H3B HIST1H3J â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
DNMT3L HIST2H3D â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
DNMT1 EZH2 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
CBX5 H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 16415788 5218238
H3C2 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 20871592 8087215
H3C2 CBX5 â—¼   PROXIMITY ✅ 0.85 0.85 mint 25281560
EHMT2 CBX1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24981860 17962312 19706462 15200951 27705803
CCND1 CDKN2A â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
CUL4B HDAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25189618 34026424
ESR1 RBBP7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23403292 31527615 18577416 21182205
CDH1 EPCAM â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
H3F3B HIST1H3I â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3F â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3C â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3J â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3H â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3J â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3J â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3H â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3H â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3I â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3I â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3F â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3F â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3C â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3C â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HIST1H3A PRMT5 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
H3F3B HIST1H3A â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
HIST1H3J SETDB1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
HIST3H3 SETDB1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
EZH2 RBX1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23238014 26496610
HIST1H3B HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3J HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3J HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3J HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3PS2 HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3C HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
DAXX DNMT1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
EHMT1 EHMT2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
ESR1 PTGES3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CCND1 ESR1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
HIST2H3D SETDB1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
DNMT3B HIST1H3A â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
KDM1A MBD3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21937684 23455924 19703393
CUL4B SUZ12 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 27634302 23238014
RBBP7 EED â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 12435631 26496610 26186194 27705803 28514442
HDAC1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16287849 26496610 23752268 28514442 26028330
EHMT2 KDM1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26751641 26028330
PIAS1 ESR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31527615 11117529 15666801
SUZ12 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26344197 22439931 24457600
MYC KDM1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 23455924 32296183 29467282
SUZ12 RBBP7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27634302 24981860 20075857 12435631 35016035 26186194 31281901 24457600 27705803 28514442
DNMT3A HIST1H3J â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CBX5 HIST1H3B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
DAXX UBE2I â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
H3F3B SMARCA4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RB1 SMARCA4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HIST2H3D HIST3H3 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HIST1H3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BRCA1 MLH1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
KEAP1 RBX1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
EHMT2 HIST2H3D â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
DNMT1 DNMT3B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HIST1H3J HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CBX5 SP100 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
UHRF1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15361834 22411829 31782885 17934516 19800870 20037778
HIST1H3J MPHOSPH8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CBX1 HIST1H3B â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CDKN2A MYC â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DCAF8 CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 33288900 21145461 16949367 28514442 31155351 31973889
DNMT1 EED â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16357870 22094255
ESR2 NRIP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21182203 15604093 11500849
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MDFI MYOG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16713569 8797820
SP100 UBE2I â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DAXX RASSF1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MYC ZBTB17 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ESR1 NRIP1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DNMT3L H3F3B â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
EHMT1 EHMT2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
RB1 RBBP7 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
RBBP4 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10220405 26831064 16713569
CCND1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9244350 16713569 17334399
HDAC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10220405 21102443 16713569
BRCA1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26831064 18025037 20016594
SP100 CBX5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9636146 27107012 11313457 32296183 21516116 15882967 31753913 25416956 16189514
CBX5 SUV39H1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CUL4B EZH2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27634302 23238014 24292684
DCAF8 DDB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 33288900 16964240 19966799 31391242 32235678 24500646 16949367 32703400 31257023 28514442 19295130 31155351
EHMT2 EHMT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 21258344 28698370 21430779 27705803 34588438 26028330
TDG ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12874288 16282588
HDAC1 SPI1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11593411 16331260 14647463
MBD4 MLH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10097147 32296183 25358258 16189514
MYC MLH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29467282 12584560
PIAS2 MYC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17418410 16352593 18923429 17471507 11283613 30415952 20426839 19786833
SUMO1 SP100 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24654937 11313457 32296183 15017387 10212234 24637324 16524884 9412458 25416956 21880768 16189514 17491593
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
HIST1H3A KDM1A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CBX1 TRIM28 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CBX1 H3F3B â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
MYC MEIS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MBD3 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 17827154 24048479 26344197 21258344 16428440 12354758 28514442 27068747 19041848 10444591 25123934 12124384 23752268
WT1 INHA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23326390 8701090 8544844
H3C2 UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
H4C6 UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
H3C14 UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
UHRF1 DNMT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22064703 21268065 26065575 33170271 28803780 19800870 31322780 29691401 27045799 33465813 24782312 27049577 20613874 24368767 21045206 17934516 19943104 21745816 17673620 29268763 19798101
DNMT3A H3F3B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TFAP2A H3C14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11835395 9776742 11018030
MYC AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19149881 24299953
MYC BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11916966 9788437 20215511 30415952 16713569 12646176 14612409
RBBP7 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11394910 10220405 11746496 16713569
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11493692 27977889 10334989 11782371 16713569 17505062 15674350 19887647 20060929 11244506 16860316 17392432 31527615 16061635 16260778 12400015 1244506 25499220 29367421
MLH1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16786532 29656893 21240188 17148452 25184681 10783165
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DNMT1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19943104 22197621 20631324
EZH2 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19079346 20574448
MYC CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
UHRF2 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21952639
DNMT3B CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20375073 16887905 18974268
WT1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23298185 23945386 10753894
CDKN1A RBBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A SETDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYOG CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25211658 16351709
RBX1 CUL4B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28446751 34026424 29499938 22038470 19250909 26496610 31973889 12481031 30349055 24292684 30945288 33969670 27113764 32140073 33504946 12609982 25189618 23238014
POU5F1 DNMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22795133 30140294
DNMT1 DNMT3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24423239 16481298 20155458
DNMT1 MT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16329111 22905112 12417732
WT1 DNMT3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23042785
DNMT3B RASSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19854132 12879017 18006804
SUZ12 EED â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
NRIP1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9115274 26153859 8887632 16439465 26166704 9192902 21182203 23403292 33731348 7641693
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
TFAP2A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10497269 19458056 9850080
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
TDG ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12874288 17129768
ESR2 TDG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HDAC1 TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18381204 21669397
SMARCA4 HIC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19015639
IRF9 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8864350 22252317 9218597
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
TFAP2A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9632747 8276360 7555706
STAT5A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17927978 12048235 12967477
WT1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15286719 17634147 20842112
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC SFRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17485441 20697356
MYC RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12695333 11085504
ZBTB17 PIAS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25043018 14704274 22053792
STAT5A TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22402124 21356308 17525530
H3F3B HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3B HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3B HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3D â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3D â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
HIST1H3A UHRF1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CBX5 HIST2H3D â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
HIST1H3A SETDB1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
CBX5 TRIM28 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
EZH2 EED â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
EED HDAC1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
H3F3B HIST2H3D â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
MBD3 RBBP7 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HIST1H3A RBBP4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PIAS1 SUMO1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MBD3 RBBP4 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
RB1 RBBP4 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
HIST1H3J RBBP4 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
EED RBBP7 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
HDAC1 RB1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
DNMT3A MPHOSPH8 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CBX5 H3F3B â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MDFI OTX1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
DNMT1 UHRF2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
EZH2 RBBP7 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
DNMT3A HIST1H3A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
CBX1 HIST3H3 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
CCND1 RB1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
EZH2 RBBP4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
RBBP7 SUZ12 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
SUV39H1 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
RB1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 6550000 10779361
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
TDG UHRF1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
CBX5 HIST1H3A â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
DNMT3B DNMT3L â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
PAF1 CDC73 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
CBX5 HIST1H3J â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
CBX1 HIST1H3J â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
PIAS2 UBE2I â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
PIAS1 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CBX1 HIST1H3A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
SUMO1 DAXX â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22578841 31879127 12150977 18583933 20972456 21816224 21474068 11112409 16475184 17081986 30958586 20927612 25409927 19465479 11948183 28851805 23395904 21383010
HDAC1 DNMT1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22274925 10888886 15870198 21670149 17707923 10615135 26794444 17967891 20613874 12473678 17934516 23708667 27593931
RBBP4 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 34518534 11302704 11102443 27705803 17827154 10734134 10220385 9885572 10471499 26344197 21258344 12091390 9150133 16713569 11602581 12920132 20127688 9790534 17643391 11470869 19686092 12943729 9150135 28514442 16189514 27068747 10444591 19703393 11171972 15451426 23752268 20585571 9520398 11118440 31435636
RBBP7 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 17255935 22939629 26496610 11102443 27705803 9885572 10471499 26344197 21258344 12920132 9790534 19686092 9150135 28514442 25885317 10444591 19703393 15451426 26186194 23752268
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
SUZ12 RBBP4 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 27634302 24981860 20075857 22939629 35016035 15225548 24457600 27705803 31281901 28514442
EED RBBP4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
UHRF1 USP7 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SUMO1 TDG â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HIST3H3 UHRF1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
HIST2H3D UHRF1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CDH1 JUP â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HDAC1 MBD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
DNMT1 USP7 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CBX5 HIST3H3 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DDB1 RBX1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DNMT1 RB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
KDM1A RCOR3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DAXX SUMO1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CUL4B RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PIAS2 SUMO1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CCND1 CDKN1A â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
DNMT3A DNMT3L â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RBBP4 SUZ12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DNMT1 UHRF1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DAXX H3F3B â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC73 PAF1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EED SUZ12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EED EZH2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
HOXA9 MEIS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10082572 15161102 9343407
UHRF1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19798101 22064703 20210320 17673620 24368767 19800870 27049577 20613874 21268065 24782312 26065575 17934516 21045206 21745816 19308066 27045799
ESR1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15208657 16029657 19440537 14991571 18669446 17932106
DNMT1 H3C2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
KDM1A H3C2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
H3C2 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C2 DNMT3L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19834512 21979949 16829525 15861382 17687327
H3C2 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
SUV39H1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16409643 19442252 11242053 10949293
PRMT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22231400 20084102 15670829
SETDB1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21243721 11791185 11252719 11959841
EHMT2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19690169 17194708 22387026
EHMT1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20084102 19010785 20118233
CBX1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 15136563 11882902 16622419 20871592 11242053 19111658 15960974 16415788 26527279
CBX5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16687578 16622419 20871592 20011120 25281560 26527279 19111658 16415788 19498464
KDM1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16223729 20210320 18343668 20228790 15620353
EZH2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18022353 15196462
KDM1A H4C6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
DNMT1 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H4C6 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H4C6 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H4C6 DNMT3L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19834512 21979949 16829525 15861382 17687327
MYC H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 12695333
PRMT5 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19234465 29227283 15670829 20951943 23071334
KDM1A H3C14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
DNMT1 H3C14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C14 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C14 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C14 DNMT3L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19834512 21979949 16829525 15861382 17687327
HDAC1 AXIN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
BRCA1 RB1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
BRCA1 RB1 â—¼   SHARES_COMPLEX 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
BRCA1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9926942 11394910 10196224 18025037 21245169 16735508 12647291
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
RB1 CCND1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
ESR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11477579 12554765 12808053 17166846 22892083 21505052 18414489 9832502 23864650 22396492 22266855 11358796 23891847 22948256 11986316 15282324 15496458 22521644 14764652 15178330 23108396 11410592 15026472 17998543 17681750 18245487 20821348 16860316 11844790 19858209 12929585 15808510 18997820 15217513 16809759 10500157 16980581 17914104
KLF4 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23884787 11005769 23861801 19737957 10908361 21132436 21224073
STAT5A CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16155412 18927468 21719533 20372799 23223023 15885880 10064602 23504816 14645506 18024957 19426693
ESR2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15313930 14764652 18607069 23891847 11986316 18223478 14729654
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
CDKN1A CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 26203195 23443559 17145710 25416956 7478582 9837900 21988832 21516116 7777546 15232106 16082198 27107012 15695403 8657154 8242751 23007395 9106657 12383116 17556661 8756624 8662825 31515488
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
ESR1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8649771 11073968 16061635 9039267
CCND1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 10498883 9315635 17303408 16236519 11520855 15279786 9190208 7575488 10385618 9736735 8490963 26225123 19237565 7736585 19075565 18590585 27507850 26121043 20068082 9425340 18786381 17660363 10778858 9380698 27430527
CCND1 SUV39H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10385618 9736735 12006580 10498883
CDH1 IFNG â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
EZH2 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18377425 22130667 21685935 21770894
TFAP2A CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9328434 17224907 12391156 10523846 9632747 21377456 12903198
MYC CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9632747 19176757 23364919 10523846
KLF4 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21746878 20356845 22854048 23451207 23376074 22407433
HDAC1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20580679 19182791 21685935 21184735 24424621 18794357
ESR1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12726856 14500345 17893710 19383788 19593637 20101232
EZH2 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 15169839 17615296 22796940 20818389 21685935 20519943 12508111 11309385 17018611 22514743 19597490 20574448 14673164
RB1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
DNMT1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21229291 21572997 19056828 16276353 9588214 21868513 23658227
KLF4 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10749849 23884787 18483411 21652709 23861801 19737957 21132436 21224073 22750490 21763782 18645021
TFAP2A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21084835 9473523 16867219 16288208 11420667 18955504 20805990 8988173 17875680 12226108
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
DNMT3A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20473858 15616584 16131836 24957603
EZH2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21572997 21546904 24074410 21629038 22956625
WT1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10224085 18202757 17160023
RBX1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11278750 15340381 12820959 15688063 18381890 19440234
ZBTB17 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9618481 12545156 17550342 17828269 10454538 15155580 11283613 11283614
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
CDKN1A RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10498883 9315635 17303408 10486249 16236519 11520855 15279786 9190208 7575488 10385618 9736735 7736585 19075565 18590585 20068082 9425340 18786381 17660363 10778858 17556661
MYC CDKN2A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
EZH2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19954516 21572997 23289480 23826727
DNMT3A CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 26350239 19786833 20620135 17490527
MYC CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15361884 11593429 11507042 20023701 23342141 16537449 23277542 10914736 9212167 12835716 24177224 11062467 15199070 18762810 19786833 20551174 11360201 23722468
DNMT3B CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23397112 18006804 22461910 17149367 21757290
MYC CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15361884 9308237 10373560 17936558 12209154 12738781 17873522 11283613 21406394 9312026 15095404 17558397 20551172 19901969 19815509 10504341
MYC CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12244100 22610535 11804592 12565816 19164764 12835716 11283613 14519204 24618291 19201832 23722468
ZBTB17 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12244100 19419955 19164764 11283613 24618291 15095404 22000024
ZBTB17 CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 10454538 9308237 17936558 11283613 9312026 15095404 19901969 19815509 11283614
MYC CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10454538 10373560 9308237 17936558 12738781 17873522 11283613 21406394 9312026 15095404 10504341 17558397 20551172 19901969 19815509 11283614
MYC CDKN2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 9308237 10373560 17936558 12738781 17873522 11283613 21406394 9312026 17093053 15095404 17558397 20551172 19901969 19815509 10504341
RBX1 DDB1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
RBX1 DDB1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DNMT1 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19454658 32905139 23687305 19109157
DNMT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21655924 20946668 17172825 15746193 22975348 12789259 19001520 24058781 23242655 22558281
SUZ12 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
RBBP4 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
RBBP7 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT3L DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11934864 25383530 15105426 12777184 15861382 17687327
EHMT2 DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19308066
RBBP7 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
RBBP4 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
SUZ12 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
EHMT2 DNMT3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19308066
KDM1A ESR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
STAT5A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11731618 22201800 11682624 11682625
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21411498 12122114 21693539 18519947 16690106 10805720 19360348 23409030 18754863
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 NRIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20200160 10379892 16391242 22071320 18414489
ESR1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16267616 12400015 17272396 18252963 18497067 10866309 19420388 19398483 16249470 14647449 15774498 12208749 10995484
NRIP1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9192902 23331499 8887632 9115274 7641693 26166704 12554755 26153859 21182203 16439465
PIAS1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15666801 11117529
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
ESR2 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12122114 10805720
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
EZH2 RRP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 24737471 19502792 21546904 22563434
EZH2 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22563434 21674483 17911618 21624129
IFNG FOXP3 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
FOXP3 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20554955 17028180 23543754 19877017 17377532 20308632
STAT5A GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10674400 7744007 8732682 11092411 12683938 18388193 22698918 19819986 22166977 11564677 14532269 17412814 12970402 10373481 15677453 10803577
UBE2I HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
SUMO1 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
UBE2I HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12820959 15340381 11960997
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
UBE2I HIC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 23417673 27935866 20547755 17283066
SUMO1 HIC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 23417673 27935866 20547755 17283066
STAT4 IFNG â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10807786 10961885 11449378 12372421 8683106 8700208 9715265
STAT4 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12759422 12902482 14734615 19359411 23761633 15251440 20620946 11449378 12594853 12893768 10097133 20574006 25589075 19710469 11801649 26123499 15522880 9558063 9642277 16717115 24415943 17110450 16301617
SPI1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15345588 19502584 12130529 7814871 9545284 20585034
STAT5A IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12759422 7875295 7796811 15528362 9831114
RBX1 KEAP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
RBX1 KEAP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
MLH1 MBD4 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10545939 12417741 12584560 14614141 15242590 15375219 15377654 15485915 15703371 15814658 16612326 16697054 16713580 16818604 17855402 18157157 18406444 18543256 18995830 19686080 19847258 20478261
MDFI MYOG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8797820 16713569
MYC VEGFA â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 76.0 1.0 Omnipath 16287840 15655249 12821782 16880523 21807113 19047367 14744757 16489011 12941894 10786671 14519204 19360348 10723141 12970752 15595642 18365874 15665468 22207128 14611815 10022128 15226182 11274400 10491298 11606399 17070091 19787269 19806010 20454512 19762557 21132266 21553143 18818322 10914736 17934056 19148473 11435602 12695333 12802280 21995449 11287602 12044867 21627565 23860446 17942561 19649288 23759068 10606235 12807729 15958520 17141225 20723213 16402390 16785237 18093727 21855630 24705139 18367227 14563552 16205635 19003324 9988278 17706770 17967894 18226852 18754863 10637317 18586674 14612409 19912441 15371341 11916966 12646176 11279234 18158869
MYC VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19738061 19147754 17785433 22002305 18809243 19398483 12368264 23028984
MYC PIAS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21811581 22053792 12545156 17471507
MYC TGFB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9196027 12695333
MYC ZBTB17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 17145710 26766587 18923429 29137325 20426839 11283613 17418410 9312026 20697356 19786833 16352593
PIAS1 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16524884 22578841 19217413 18806873 14609633 11583632
PIAS2 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16204249 21988832 25416956 19217413 16189514 14609633 16524884 12764129
PIAS2 STAT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 12716907 16189514
TFAP2A RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11835395 9632747 21850486 9776742
TRIM28 SETDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11959841
SMARCA4 TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19571879 24550003
TFAP2A SUMO1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12072434 24835590 25114211 21375726
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
SUMO1 TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 16763556 15959518 17060459 21284855 20504299 16189514 16524884 11889051 10961991
UBE2I TDG â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15823533 18691969 21284855 15959518 11889051
UBE2I TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18512959 24753249 18691969
WT1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12807729 22654424 20842112 10601322 18754863
TFAP2A VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11191053 16790435 11731421 9049304 12570801 14744778 8466753 11007955 23506169
UBE2I TRIM28 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17942393 17079232 25114211 18488044 17298944 18082607
TDG TWSG1 â—¼   KO_UP_REGULATES ✅ + 1.18 1.18 PKG 28854368
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
MGMT MGMT â—¼   KO_DOWN_REGULATES ✅ - -4.42 4.41 PKG 28854368