Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TDG APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11864601
HTT APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MBD4 CSNK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14667819 5216829
DNMT3B DNMT3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20426865 15362956
TDG DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17175537
DNMT3A TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17175537
UBE2I DNMT3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18762900 11735126
DNMT3B SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16371653 17584191
FADD FAS â—¼   COLOCALIZATION 2.0 0.8 intact 16498403 5218359
UBE2I HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TFG HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MBD4 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
UBE2I MBD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17066076 16757475
MBD1 MBD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12101420 20886097
TRIM27 MBD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MBD4 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PSMD1 MBD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DNMT3A DNMT3B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
MBD4 HD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23275563 32814053
HD FAS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32814053 25959826
ESR1 APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
ESR1 FAS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
ESR1 KDM1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17289570 23403292 31527615
TRIM27 USP7 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HDAC1 UHRF1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 PSMD1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 20348541
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
UHRF1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15361834 22411829 31782885 17934516 19800870 20037778
ESR1 GATA3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26153859 23403292 25303530
GATA3 KDM1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 35140242 26028330 31409898
MBD4 TRI27 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17049487 21516116
TDG ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12874288 16282588
MBD4 FADD â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16189514 12702765
GATA3 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 34026424 29453984 26028330 31409898
MBD4 MLH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10097147 32296183 25358258 16189514
APEX1 TDG â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11889051 15823533 18805789
CDCA2 MBD4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TDG ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12874288 17129768
SIN3A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12724404 24981860 14593184 26496610 11102443 17827154 10220385 14647463 9885572 15695521 12398767 26344197 21258344 9804427 16331260 12091390 9150133 11602581 10640275 12920132 9790534 17643391 12943729 19182791 25314079 12374985 28514442 26949739 10444591 11931768 11171972 17956988 12453419 15451426 23752268 11784859 18059533 20585571 9520398 11118440 17962807
TDG UHRF1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
FAS FADD â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219431 17159907
FAS FADD â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16498403 5218359
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
UHRF1 USP7 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
KDM1A ESR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
GATA3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17616709 20130088 20068169
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26153859 25303530 10096242
FADD FAS â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
FADD FAS â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
FAS FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 22864571 8521815 11717445 21713032 16762833 23606538 8967952 20935634 7538907 21803845 9325248 19118384 12721308 21959933 18328427 16189514 25563855 10196099 17159907 27321185 26186194 25241761 9880544 16498403 21625644 9082980 12107169 15659383 15993755 21382479 7536190 11464215 26942442 11035039 15725726 16410793
UBE2I HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
UBE2I HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12820959 15340381 11960997
MLH1 MBD4 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10545939 12417741 12584560 14614141 15242590 15375219 15377654 15485915 15703371 15814658 16612326 16697054 16713580 16818604 17855402 18157157 18406444 18543256 18995830 19686080 19847258 20478261
UBE2I TDG â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15823533 18691969 21284855 15959518 11889051
UBE2I TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18512959 24753249 18691969
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368