OGG1
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11139613
25086253
|
APEX1
|
OGG1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20185827
17203305
|
TDG
|
APEX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11864601
|
FEN1
|
TDP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
POLD1
|
FEN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7876218
8131753
|
PCNA
|
FEN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7876218
8131753
|
FEN1
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7876218
8131753
|
FEN1
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7876218
8131753
|
FEN1
|
POLD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7876218
8131753
|
HMGB1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ESR1
|
HMGB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17922863
18414489
|
MBD4
|
KDM1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
SUV39H1
|
KDM1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
PNKP
|
KDM1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
TRIM27
|
MBD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
PSMD1
|
MBD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
MBD4
|
CSNK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14667819
5216829
|
MBD4
|
SUV39H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
MBD4
|
FADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216332
12702765
|
MBD1
|
MBD4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12101420
20886097
|
XRCC1
|
MPG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18971944
7294748
|
MPG
|
MBD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17129768
|
POLL
|
MUTYH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0907280106
19820168
|
POLB
|
NEIL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16982218
15260972
|
PNKP
|
SUV39H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
POLD1
|
POLD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
10852724
|
POLE2
|
POLE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
32296183
|
POLL
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18971944
7294748
|
DNMT3B
|
SUV39H1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16371653
17584191
|
DNMT3A
|
TDG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17175537
|
TDG
|
DNMT3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17175537
|
XRCC1
|
TDP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19851285
7542621
|
HDAC1
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18691180
9650586
|
FADD
|
FAS
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16498403
5218359
|
HTT
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10823891
5212595
|
UBE2I
|
MBD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17066076
16757475
|
UBE2I
|
DNMT3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18762900
11735126
|
UBE2I
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TFG
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTT
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
DNMT3B
|
DNMT3A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20426865
15362956
|
ESR1
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19805454
31527615
|
MBD4
|
HD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23275563
32814053
|
ESR1
|
FAS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19805454
25604459
|
HD
|
FAS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32814053
25959826
|
DNMT3A
|
DNMT3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.82
|
STRING
|
36370105
|
ESR1
|
KDM1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
23403292
17289570
31527615
|
PCNA
|
UHRF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
30357346
26496610
|
TRIM27
|
USP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
HDAC1
|
UHRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
PARP1
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
FEN1
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
FEN1
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
PCNA
|
POLE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
PARP3
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12640039
20064938
|
PARP1
|
UHRF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
34079125
24782312
31964471
|
ESR1
|
PSMD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25604459
20348541
|
PCNA
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16189514
11601988
10559261
|
MLH1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15225546
32814904
28439008
|
PCNA
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20129057
20302655
12930846
21690293
20303835
|
PARP1
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
16204234
20596014
19470756
|
OGG1
|
XRCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12933815
16713569
|
PCNA
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
FEN1
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
11601988
|
XRCC1
|
APTX
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
15555565
5217319
|
PARP1
|
HMGB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
29721183
28190768
34079125
|
GATA3
|
KDM1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
35140242
26028330
31409898
|
NEIL1
|
XRCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15260972
16713569
33961781
|
PARP2
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19629035
12217960
11948190
|
POLD2
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
31449058
|
UHRF1
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15361834
20037778
17934516
22411829
19800870
31782885
|
ESR1
|
GATA3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
26153859
23403292
25303530
|
PNKP
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
XRCC1
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19934257
28986522
16713569
11707423
|
HDAC1
|
KDM1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16079794
19703393
21258344
34050636
11102443
27183383
16140033
21937684
12032298
26496610
22143567
19497860
11171972
17634443
12493763
20856864
20585571
31130994
21670149
26344197
23752268
32882276
17687328
33961781
24981860
28667074
|
MBD4
|
FADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
12702765
|
MBD4
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
32296183
10097147
16189514
25358258
|
MBD4
|
TRI27
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17049487
21516116
|
MUTYH
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
26377631
11092888
|
POLG2
|
POLG
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
6167829
17762861
|
TDG
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12874288
16282588
|
GATA3
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29453984
34026424
26028330
31409898
|
APTX
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
POLB
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
APEX1
|
TDG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11889051
15823533
18805789
|
MUTYH
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
11092888
24209961
28986522
19820168
|
MUTYH
|
APEX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19820168
16189514
11092888
|
XRCC1
|
APTX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15380105
16713569
15555565
15044383
26496610
16964241
15367657
|
APTX
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15044383
16713569
15555565
|
CDCA2
|
MBD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MPG
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17129768
14761960
|
OGG1
|
NEIL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15260972
11904416
12097317
|
XRCC1
|
NEIL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16982218
15260972
11163244
|
NEIL1
|
PNKP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16982218
15260972
11163244
|
PARP1
|
PARG
|
â—¼ DE_ADP_RIBOSYLATION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17548475
21398629
15607977
|
XRCC1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
15555565
9584196
18971944
24778456
15044383
34111398
14500814
30260704
20302655
12897160
34079125
20303835
|
PNKP
|
XRCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11163244
15385968
16713569
17353931
21637298
26496610
34111398
15367657
19155274
|
POLD2
|
POLD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16000169
10852724
16510448
|
POLE4
|
POLE3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
6693436
10801849
9405441
|
TDG
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12874288
17129768
|
XRCC1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
15107487
34111398
30260704
20227374
|
HDAC1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11929879
16189514
16713569
14988403
|
SIN3A
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15695521
28514442
9520398
10640275
14647463
12398767
9150133
10444591
14593184
21258344
12943729
12374985
17956988
11102443
9885572
17962807
26496610
12453419
11171972
16331260
20585571
10220385
25314079
12091390
11931768
17643391
11602581
17827154
12724404
11784859
23752268
18059533
9790534
9804427
26949739
24981860
33961781
19182791
11118440
15451426
12920132
26344197
|
ESR1
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17312152
31527615
24051437
33731348
14722073
21182205
15557281
18451880
14506733
15140878
|
POLD2
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
POLD3
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
POLE2
|
POLE4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
POLE3
|
POLE4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
RFC2
|
RFC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
22939629
9488738
26344197
24981860
|
PCNA
|
POLL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
FEN1
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
POLE
|
POLE4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
RFC2
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9228079
12171929
24958773
26496610
8093561
|
PCNA
|
RFC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12171929
24958773
12766176
14657243
10051561
9092549
26344197
|
RFC3
|
RFC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
33961781
24981860
22939629
26344197
|
RFC5
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9228079
12171929
16189514
24958773
8999859
|
FAS
|
FADD
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
5219431
17159907
|
FAS
|
FADD
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
16498403
5218359
|
FEN1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
16189514
17115032
7673186
8876181
1477073
14657243
16216273
26030842
31467278
26496610
11430825
12853968
26751069
32900933
22592530
8668533
26264872
11313979
30184152
24958773
24728180
11601988
9545252
9178907
15616578
9305916
18692475
29997244
22556262
15576034
33961781
26186194
22606318
|
PCNA
|
RFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12171929
12192049
22939629
9649448
15225546
24958773
12045192
26496610
10353443
8861969
30301766
9092549
8999859
12400013
26344197
|
RFC1
|
RFC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9488738
14681455
15655353
18245774
22939629
26344197
|
PCNA
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9228079
12171929
16189514
22939629
24958773
26496610
10051561
12400013
|
HDAC1
|
KDM1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
POLG
|
POLG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
UHRF1
|
USP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
POLE2
|
POLE3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
LIG3
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
RFC1
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
28514442
9488738
22939629
14681455
33961781
18245774
9092549
26344197
|
RFC1
|
RFC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
28514442
9488738
14681455
33961781
18245774
22939629
26344197
|
POLE
|
POLE3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
LIG1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
RFC3
|
RFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
9488738
8692848
14681455
18245774
22939629
26344197
|
RFC2
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
9228079
9751713
28514442
9488738
22939629
8692848
15655353
33961781
24981860
16582606
9092549
26344197
|
RFC3
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
32296183
9488738
22939629
8692848
33961781
9092549
26344197
|
POLD1
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
FEN1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
POLD2
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
POLE
|
POLE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RFC1
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RFC2
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RFC3
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
UNG
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9724657
15479784
25086253
9200707
|
PARP1
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
17548475
11440997
12727891
15135726
10364231
11340072
9804757
|
LIG1
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
PCNA
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
APEX1
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
APEX1
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
APEX1
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
APEX1
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
FEN1
|
APEX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11601988
16189514
|
PARP1
|
APTX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15555565
19643912
15044383
16713569
|
PARP1
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
25642960
25789972
11440997
25643323
20483915
25642963
15135726
16012167
11340072
|
POLB
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
21183466
19778542
20573551
11440997
15731342
6278323
15193131
|
PCNA
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
11283614
11756412
12202749
14624239
14726013
15385537
15703371
15871698
16216273
16449207
16697054
17055429
17116323
17965729
18398454
18524993
18558713
18584027
18809224
19068479
19490890
1974050
19847258
20027199
20056333
20064462
20691907
20713526
21376743
2191300
22021614
22657828
22743550
22973052
23082994
23161013
23253856
23414611
24036544
24050180
24709898
|
POLD1
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
FEN1
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
PCNA
|
FEN1
|
â—¼ SHARES_COMPLEX
|
|
|
41.0
|
1.0
|
ACSN
|
11283614
11756412
12202749
14624239
14726013
15385537
15703371
15871698
16216273
16449207
16697054
17055429
17116323
17965729
18398454
18524993
18558713
18584027
18809224
19068479
19490890
1974050
19847258
20027199
20056333
20064462
20691907
20713526
21376743
2191300
22021614
22657828
22743550
22973052
23082994
23161013
23253856
23414611
24036544
24050180
24709898
|
PCNA
|
FEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
28514442
15576034
8668533
3113402
11601988
12853968
31467278
1477073
24958773
7673186
16216273
11313979
15616578
8876181
14657243
11430825
26496610
16189514
9305916
22606318
28073635
19153658
26751069
26186194
9178907
22592530
24728180
17115032
18692475
26030842
16326861
29997244
22556262
9545252
31515488
|
KDM1A
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17277772
24371278
19098913
18187655
|
PARP1
|
LIG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11900249
12648680
14726013
15703371
16697054
17088286
17116881
17884153
18524993
19208614
19362533
19364882
19809470
19847258
20056333
20211143
20227374
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
8264637
8978692
|
XRCC1
|
LIG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11900249
12648680
14726013
15703371
16697054
17088286
17116881
17884153
18524993
19208614
19362533
19364882
19809470
19847258
20056333
20211143
20227374
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
8264637
8978692
|
XRCC1
|
LIG3
|
â—¼ PROTEIN_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11900249
12648680
14726013
15703371
16697054
17088286
17116881
17884153
18524993
19208614
19362533
19364882
19809470
19847258
20056333
20211143
20227374
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
8264637
8978692
|
PARP1
|
LIG3
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11900249
12648680
14726013
15703371
16697054
17088286
17116881
17884153
18524993
19208614
19362533
19364882
19809470
19847258
20056333
20211143
20227374
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
8264637
8978692
|
LIG3
|
XRCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9705932
20227374
17353931
11163244
26496610
16713569
8264637
11352725
9136882
|
MLH1
|
MBD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
10545939
12417741
12584560
14614141
15242590
15375219
15377654
15485915
15703371
15814658
16612326
16697054
16713580
16818604
17855402
18157157
18406444
18543256
18995830
19686080
19847258
20478261
|
MLH1
|
MBD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
10545939
12417741
12584560
14614141
15242590
15375219
15377654
15485915
15703371
15814658
16612326
16697054
16713580
16818604
17855402
18157157
18406444
18543256
18995830
19686080
19847258
20478261
|
PCNA
|
MLH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
20154325
22118461
11274057
23840062
|
PCNA
|
NEIL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18032376
|
PARG
|
PARP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
196269035
22469522
22713970
23110147
24684389
|
PARG
|
PARP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
196269035
22469522
22713970
23110147
24684389
|
PARG
|
PARP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
22469522
22713970
196269035
17276427
|
PCNA
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
15871698
16697054
16731526
17088286
17116881
19208614
19364882
1974050
19847258
20056333
20603072
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
PARP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
14726013
15703371
16697054
17088286
17116881
18077224
19208614
19364882
196269035
19847258
20603072
21211721
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23178593
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
PARP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
18835851
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21037379
21060331
21076181
21270334
21337561
21376743
21818122
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
PARP1
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
70.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11900249
11948190
12032095
12202749
12637553
12648680
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17884153
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19748837
19809470
19847258
20027199
20056333
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
POLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
72.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11756412
11948190
12032095
12202749
12637553
14624239
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18087292
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
1974050
19748837
19772495
19847258
20027199
20064462
20211143
20227374
20478261
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22021614
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23414611
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
PARP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
18835851
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21037379
21060331
21076181
21270334
21337561
21376743
21818122
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
PARP1
|
PARP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
14726013
15703371
16697054
17088286
17116881
18077224
19208614
19364882
196269035
19847258
20603072
21211721
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23178593
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
PARP1
|
â—¼ SHARES_COMPLEX
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
POLB
|
â—¼ SHARES_COMPLEX
|
|
|
72.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11756412
11948190
12032095
12202749
12637553
14624239
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18087292
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
1974050
19748837
19772495
19847258
20027199
20064462
20211143
20227374
20478261
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22021614
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23414611
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
XRCC1
|
â—¼ SHARES_COMPLEX
|
|
|
70.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11900249
11948190
12032095
12202749
12637553
12648680
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17884153
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19748837
19809470
19847258
20027199
20056333
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
LIG1
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
15871698
16697054
16731526
17088286
17116881
19208614
19364882
1974050
19847258
20056333
20603072
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
XRCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
9592149
18971944
15555565
19643912
15044383
14500814
16713569
24778456
12897160
20303835
20302655
9584196
|
XRCC1
|
PARP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
54.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17116323
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
23082994
23161013
23253856
24036544
24050180
24709898
8264637
8978692
|
PARP2
|
POLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
54.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17116323
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
23082994
23161013
23253856
24036544
24050180
24709898
8264637
8978692
|
XRCC1
|
PARP2
|
â—¼ SHARES_COMPLEX
|
|
|
54.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17116323
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
23082994
23161013
23253856
24036544
24050180
24709898
8264637
8978692
|
PARP2
|
POLB
|
â—¼ SHARES_COMPLEX
|
|
|
54.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17116323
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
23082994
23161013
23253856
24036544
24050180
24709898
8264637
8978692
|
XRCC1
|
PNKP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
21637298
17353931
11163244
28821613
19155274
15367657
15385968
26496610
16713569
|
LIG1
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
POLB
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
POLD4
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD1
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD1
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD4
|
POLD1
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD1
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD1
|
POLD3
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD1
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
9286699
12403614
16510448
|
POLD1
|
POLD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
12403614
16510448
|
POLD4
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
LIG1
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
POLB
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
PCNA
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD3
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD3
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD4
|
POLD3
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD3
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD2
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD3
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLB
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
LIG1
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
PCNA
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD4
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD4
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD4
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD2
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
PCNA
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
PCNA
|
POLD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24022480
9038370
16510448
|
PCNA
|
POLL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12368291
11784855
16174846
16189514
12081642
|
PCNA
|
RFC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8999859
12400013
15225546
19285992
10353443
12192049
9649448
26496610
12045192
12171929
24958773
8861969
9092549
|
RFC5
|
RFC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
9228079
9751713
28514442
9488738
8692848
33961781
24981860
22939629
26344197
|
RFC5
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
9228079
9751713
16189514
9488738
25416956
22939629
28514442
29892012
32296183
26264872
8692848
33961781
24981860
30021884
9092549
26344197
|
UBE2I
|
TDG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15823533
18691969
21284855
15959518
11889051
|
UBE2I
|
TDG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
18512959
24753249
18691969
|
PCNA
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
XRCC1
|
POLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
65.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PCNA
|
XRCC1
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
XRCC1
|
POLB
|
â—¼ SHARES_COMPLEX
|
|
|
65.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
XRCC1
|
POLB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
15107487
26186194
8978692
16442856
15520167
11467963
26496610
15367657
25423885
16713569
|
PCNA
|
POLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
40.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
16442856
16697054
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
POLB
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
POLB
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9685411
12200445
19329425
8663274
11554294
|
POLB
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
PCNA
|
POLB
|
â—¼ SHARES_COMPLEX
|
|
|
40.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
16442856
16697054
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
15871698
16697054
16731526
17088286
17116881
19208614
19364882
1974050
19847258
20056333
20603072
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
PCNA
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
PCNA
|
LIG1
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
15871698
16697054
16731526
17088286
17116881
19208614
19364882
1974050
19847258
20056333
20603072
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
POLD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
LIG1
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12171929
9649448
28073635
10559261
|
LIG1
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
FADD
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
52.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9184224
9217161
9488730
9759866
|
FADD
|
FAS
|
â—¼ SHARES_COMPLEX
|
|
|
52.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9184224
9217161
9488730
9759866
|
FAS
|
FADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
62.0
|
1.0
|
Omnipath
|
22864571
8521815
11717445
21713032
16762833
23606538
8967952
20935634
7538907
21803845
9325248
19118384
12721308
21959933
18328427
16189514
25563855
10196099
17159907
27321185
26186194
25241761
9880544
16498403
21625644
9082980
12107169
15659383
15993755
21382479
7536190
11464215
26942442
11035039
15725726
16410793
|
UBE2I
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11960997
12032081
15199155
24068740
|
HDAC1
|
SIN3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
SIN3A
|
â—¼ SHARES_COMPLEX
|
|
|
27.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
SIN3A
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21655924
23242655
18316616
20101232
|
UBE2I
|
HDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12820959
15340381
11960997
|
GATA3
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17616709
20130088
20068169
|
ESR1
|
GATA3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26153859
25303530
10096242
|