Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H4C6 CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CBX5 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19834512 7297014
E2F5 CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21374739
E2F4 CBX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
MYC CCT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DDB1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
DDB1 AHR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
RUNX1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16917507 5218981
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20428248
EP300 H3C14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11509556
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
LZTS2 GFI1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RB1 MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218170 16374512
PML MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
MDM2 PML â—¼   COLOCALIZATION 2.0 0.8 intact 5216620 12915590
S100A4 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20591429
AHR MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114727 16091746
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
E2F5 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17132729
NFATC2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23858296 22333584
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
MYC PGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18809243
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
CDC73 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18987311
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
E2F5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12150994 18319725
MYC DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15616584 19786833
RUNX1 NFATC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17377532 16873067
NFATC2 FOXP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17377532 16873067
TAL1 RBBP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
H4C6 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3-3B RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
RBBP7 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C14 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H3C2 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
DVL3 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0911325107 20439735
H3-3B SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H4C6 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H3C2 SIRT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15469825 18485871
H3C14 SIRT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15469825 18485871
H4C6 SIRT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15469825 18485871
H3-3B SIRT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15469825 18485871
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
SMAD3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
SIRT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27776347 28583374
SIRT1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19270680
H3C2 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11242053 5213683
SUV39H1 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
SUV39H1 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
SUV39H1 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
DNMT1 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17172825 17584191
DNMT3B SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16371653 17584191
SUV39H1 BCL11B â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
HDAC3 TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18037959
USP7 DAXX â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 6799761 18566590
H4C6 KMT5A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15964846 21779408
NDUFV2 PPP1R16A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD3 MYOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18753451 20471380
CTNNB1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18948405 15031118
SMAD3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11711431
RB1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21902831 8381715
RARA SCD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11397803
E2F4 MCM3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799066
E2F4 RBL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12789259 18319725
E2F4 MCM6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067 18319725
E2F4 MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
E2F4 RBBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
SMAD3 RUNX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16135801 10531362
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
SMAD3 AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11259615
SMAD3 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11331591 21612856
SMAD3 FOXP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19701891 15367216
TAL1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
BCL11B HDAC1 â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
RB1 HDAC1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
HDAC1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10220385
TAL1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
RB1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211419 10228159
HDAC2 BCL11B â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
HDAC2 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
PGK1 HDAC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1002243 26356530
HDAC3 MECP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23770587 23770565
HDAC3 BCL11B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219549 17245431
HDAC3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15292260 18321663
HDAC3 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17694085
MCM6 MCM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
NDUFV2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NDUFV2 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RUNX1 MECOM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22689058
HDAC5 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 16613856
MECP2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 AHR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
RARA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10607566 23331499
H4C6 DNMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DNMT1 RRP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17172825 18049164
THRA ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11578528 11687272
E2F5 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12789259 18319725
DNMT3B DNMT3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20426865 15362956
TAL1 CHD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
H3-3B RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4C6 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
RBBP4 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
MBD2 MECP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11865062 20886097
TAL1 BCL11B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
TAL1 RB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
H3C14 MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
H3C2 MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
H3-3B MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
H4C6 MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
MBD1 DVL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
RRP8 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
RRP8 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
RRP8 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
RRP8 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
GFI1B TNS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DDB1 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 34026424 25189618 24249678 26679995
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
EP300 CHD4 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 26546801 30110629 32699137 15189737
DAXX H3-3B â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 24981860
CBX1 CBX3 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
H3F3A UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST2H3A UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
MYC CBX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CBX1 RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
UHRF1 CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 28803780
MYC CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MECP2 CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 22615490
DAXX CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 24981860
DNMT1 CBX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17470536 12867029
DAXX CBX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26496610
CBX5 MECP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22615490 17698499
MDM2 CUL4B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28225217 22032989
CUL4B RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23238014 34026424
DDB1 AHR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19651607 17392787
EP300 SMAD5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16516194 16613856
CDC73 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 26687678
MCM3 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RUNX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC MCM6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC DNMT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
HDAC2 ZBTB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26949739 33301849
SMAD3 RUNX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10531362 15897867
ESR1 PGK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DNMT3A DNMT3B â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
MECP2 RRP8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RBL2 RBL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15467457 17531812
GGT7 PIGB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BPNT1 MOCS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DAXX H3F3A â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DNMT3A H3F3A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
H3F3A SIRT5 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
HIST2H3A SIRT5 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
HIST1H3A SIRT5 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CHD4 H3F3A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CHD4 HIST2H3A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
H3F3A SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3A SETDB1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3A KMT2C â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
H3C2 CBX1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16415788 5218238
CBX1 H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16415788 5218238
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
PML SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 15356634
RBBP7 ZBTB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 33301849 26186194
HDAC1 ZBTB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 33301849 26496610 33961781
DNMT1 RUNX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15735013 28533407
ESR1 MBD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20300195 31527615
CHD4 MBD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28977666 24981860 32744500
CBX3 H3F3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX3 HIST2H3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 H3F3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST2H3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
DNMT3A HIST2H3A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
DNMT3B HIST2H3A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
CBX5 DNMT3B â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HDAC1 UHRF1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DDB1 HIST1H3A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CTNNB1 SMAD3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CBX1 SUV39H1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
HDAC2 FOXP3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19276356 25609649
ESR1 HDAC4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19893013 16051668
HDAC4 RUNX3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24229708 15138260
HDAC5 RUNX3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24229708 15138260
ESR1 PA2G4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
HDAC2 PML â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CTNNB1 RUVBL2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CBX1 HIST2H3A â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CBX1 H3F3A â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
HIST1H3A RUVBL2 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
DAXX HDAC1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
DNMT1 HDAC2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
H3C2 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 20871592 8087215
CBX5 H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 16415788 5218238
H3C2 CBX5 â—¼   PROXIMITY ✅ 0.85 0.85 mint 25281560
CUL4B HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618
CUL4B HDAC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30737378 34026424 25189618
RUNX1 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14752096 16917507
EP300 MCM3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
MYC HDAC3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23079660 31155734 22002311 18483244
ESR1 RBBP7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18577416 23403292 21182205 31527615
CDC73 CEP70 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 21900206 2001699 8089645
SMAD3 RUNX3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10531362 27497248 15138260
H3F3A HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HDAC1 RUNX1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MBD2 RBBP7 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
HDAC1 MECP2 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
AHR RB1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
EP300 RUNX3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24229708 15138260
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
HDAC3 ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31527615 16469706 14722073 26487511 20348541
TAL1 RUNX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21179004 19497860
HDAC4 RBBP4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31040226 10220385
ESR1 RARA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9717844 25303530 25604459
RBL2 RBBP4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 33961781 17531812
SMAD5 RUNX2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10531362 22966907
HIST1H3A HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
DAXX DNMT1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
EP300 RUNX2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CBX1 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20850016 27705803 24981860 21888893 28977666
CBX3 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 33961781 21888893 24981860 28977666
CBX5 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32744500 27705803 24981860 15882967 28977666
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
MYC HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 22286234 30415952
MBD2 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 24981860 26186194 11297506
HDAC1 RUVBL2 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
E2F4 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23060449 9858615 9724731 21102443
DAXX HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10669754 12140263
HDAC3 RBBP4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11777905 16189514 11470869
DNMT3B HIST1H3A â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
CBX1 CHD4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CBX3 CBX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MDM2 PML â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AHR ESR1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PML RARA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRINP1 SIRT1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
DNMT1 DNMT3B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
AHR EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10999956 17392787 21988832
PML HDAC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11259576
UHRF1 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15361834 20037778 17934516 22411829 19800870 31782885
SMAD3 RBL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 12150994
HDAC1 CHD4 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 26949739
TAL1 HDAC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16407974 19497860
HDAC5 HDAC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10869435 10220385 11466315 11931768 11804585 21081666
HDAC3 RUNX2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15292260 18321663
PGK2 PGK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
MBD2 DNMT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10947852 27593931
DAXX MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MDM2 RB1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 MYOD1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CBX3 TRIM28 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CBX5 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27705803 24981860 21888893 15306854 15882967 20562864
DDB1 RBX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22118460 20870715 16473935 15448697 16678110 30349055 33504946 16751180
MDM2 DAXX â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6799761 18566590
MDM2 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12897156 11178989 16713569 10766163 17545634 31012223
MYC PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17146439 15735755 21150319 32592588 30415952
MYC CHD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17314511 30415952 29467282
RARA PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11050004 1311253 16189514 16713569 16540467 10882117 17560333 18073335 10610177 12935927 20159610
PML HDAC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25812002 18073335 11259576 18644863
RB1 RBBP7 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
CHD4 RBBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 22939629 9790534 25247294 33961781 26186194 28977666
HDAC1 MYOD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11285237 11684023 16713569 20124407
SMAD3 RUNX2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10531362 10962029 21986102
MECP2 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14647463 12473678 16331260 14593184
HDAC2 DNMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23708667 17967891 21670149 10888872
AHR ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15837795 19460354 12612060 27420286 17392787 10620335 9611253
CHD4 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9790534 28977666 27705803 32744500 33961781 24981860 21670149 22939629 9885572 26344197
MBD2 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27705803 10471499 33961781 24981860 25753662 11297506
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
CBX5 SUV39H1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CBX1 TRIM28 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CBX1 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314413 11336697 16713569 27705803 33961781 21888893 24981860 34079125
CBX5 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314413 11336697 16713569 20850016 27705803 20231385 33961781 21888893 24981860 15306854 34079125 20562864 19498464
MYC CBX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
CBX5 MBD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12697822 12711603 16713569 19498464
MYC CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
CBX5 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19834512 17403666 19111658
ESR1 CCAR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21596782 20074560 17473282
MYC CCT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
RBX1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33969670 24292684 12481031 25189618 12609982 26496610 30349055 27113764 29499938 19250909 22038470 34026424 28446751 31973889 23238014 33961781 33504946 30945288 32140073
CUL4B DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19651607 33969670 33357448 28225217 24292684 25189618 21145461 18593899 26496610 16678110 16964240 33536335 27113764 29499938 30898011 28886238 29738775 17392787 29846670 22939629 22038470 34026424 16949367 31911655 28446751 17041588 23238014 31973889 16861906 33961781 30945288 26344197 32140073
EP300 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15154850 20234175 16713569 11070080 9809062 28196907 15013777
EP300 TAL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11756538 11118214 10490830
EP300 MYOD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20364308 12665587 20037778 17964260 35140242 10944526 9862959 9001254 8621548
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20851880 22298955 12697832
HDAC1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15640443 33985974 12426395 30818224
MDM2 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22869143 16713569 12915590 23169665 14507915 19150978 20972456 15195100 12759344
TRIM28 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16107876
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
GFI1B MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19522008
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
MYC LTA4H â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840 12808131
MYC MBD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC PLA2G4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC MTHFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC ARSB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SRD5A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24951594 12695333
MYC SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
E2F4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11564866 12150994 18319725
NFATC2 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25126782 16517728 17463169
HDAC1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 11259576 18644863 25812002 11430826 23563092
RBBP4 RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17255935 27705803 22863883 33961781 24981860 26186194 15451426 22939629 26344197
SIRT1 WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18203716 20428248
HDAC1 TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18381204 21669397
H3C2 UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
H4C6 UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
H3-3B UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
H3C14 UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
UHRF1 DNMT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20613874 22064703 19798101 33170271 17673620 29691401 19800870 21045206 29268763 33465813 21268065 21745816 24782312 27045799 19943104 17934516 28803780 31322780 27049577 26065575 24368767
TAL1 PADI6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20028976
CEP70 CDC73 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
E2F4 RBL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17671431 21102443 12006580 9858615 17531812 9121766 9343408 17159899 11573202 23108140 22002537 20133863 16600870 12401786
E2F4 RBL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17671431 16360038 12150994 9501179 8657117 7958924 9233764 9858615 8832394 7958925 8643455 9343408 9724731 11573202 12401786
E2F4 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17531812 16738312
E2F4 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17531812 12789259 20946668
RARA SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21310893
MECOM SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23858473 9665135
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
RUNX1 HDAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
MBD2 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 12665568 10471499 10444591 26496610 21258344 33961781 27173435 24981860 27593931 11102443 17634443 11297506 12183469
CHD4 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25247294 32744500 21258344 11102443 28977666 9885572 26496610 20585571 10220385 22075476 21670149 22939629 23752268 27616479 9790534 9804427 26949739 20693977 33961781 24981860 12920132 26344197
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
HDAC1 RUNX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18430739 22274925 18850007
HDAC2 MBD2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 26949739 10471499 10444591 16410616 21258344 24981860 11297506 25753662 12183469 26344197
HDAC2 CHD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 9790534 9804427 11003653 22939629 30737378 28977666 26949739 32744500 21258344 24981860 21670149 12493763 9885572 10545197 26344197
HDAC3 HDAC4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31040226 10220385 10869435 11466315 11804585 17956988 27684187 18558095
CTNNB1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16575901 16043491 24692107
DVL3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10644691 10806215
DNMT1 DNMT3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24423239 16481298 20155458
MECP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21655924 23242655 15870696
RUNX2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17350616
THRA RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
RARA THRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
E2F5 RBL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7760804 11756542 16600870 17531812
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
KRTAP10-7 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
H3F3A HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
HIST1H3A UHRF1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
E2F4 RB1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
HIST1H3A SETDB1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
CBX5 TRIM28 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HIST1H3A RBBP4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
RB1 RBBP4 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
HDAC3 HDAC4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
E2F5 RBL2 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
HDAC3 HDAC5 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
MDM2 USP7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HDAC1 RB1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
EP300 HIST1H3A â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
DAXX PML â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CHD4 HDAC2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
FOXP3 SMAD3 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
DNMT3A HIST1H3A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
FOXP3 NFATC2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CHD4 RBBP7 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CHD4 RBBP4 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CHD4 HDAC1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
COX5A NDUFB6 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
SUV39H1 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
RB1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 6550000 10779361
HDAC1 RBL2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 9858615 9724731 10969803
CBX5 HIST1H3A â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
COX5A NDUFAB1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
DAD1 STT3A â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
HDAC1 TAL1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10688671 16407974 19497860
HDAC1 RBL1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10490602 9724731 16189514
COX5A NDUFV2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CHD4 HIST1H3A â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
E2F5 RBL1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CBX3 HIST1H3A â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
HDAC2 MBD2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CBX1 HIST1H3A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
E2F4 RBL2 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
COX5A NDUFV1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CBX1 CBX5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17314413 11336697 27705803 24981860 21888893 20562864
USP7 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6799761 18566590
DAXX MDM2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 23405218 18566590 18583933 16845383 15364927 20195357 28875283 23038753 21134643
DAXX PML â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30292834 21482821 21474068 10669754 14517282 12529400 20972456 15350595 10545115 21779164 11244500 32545337 17081986 12595526 15710327 21840486 17419608 12150977 24637324 10684855 17360386 10525530 23222847
HDAC2 RBBP7 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 20388487 27705803 21258344 33961781 24981860 26186194 15451426 12493763 9885572 26344197
RBBP7 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19703393 10444591 21258344 11102443 9885572 17255935 10471499 26496610 25885317 22939629 9150135 23752268 9790534 27705803 33961781 26186194 19686092 15451426 12920132 26344197
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
DAXX HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 24550390 12529400 10669754 29084956 32545337
RBBP4 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 9520398 19703393 31435636 9150133 10444591 21258344 12943729 11102443 9885572 27068747 10471499 26496610 34518534 20127688 11171972 10734134 11470869 20585571 10220385 12091390 17643391 21670149 11602581 17827154 22939629 9150135 23752268 16713569 9790534 27705803 19686092 24981860 33961781 11302704 11118440 15451426 12920132 26344197
HDAC1 DNMT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22274925 20613874 26794444 10615135 10888886 17707923 17934516 15870198 21670149 27593931 17967891 12473678 23708667
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
MCM3 MCM6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15232106 28514442 16189514 22939629 12614612 26496610 22863883 27621311 33961781 30108253 17296731 26344197
E2F4 RBL1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
UHRF1 USP7 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MBD2 RBBP4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
DNMT1 USP7 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
DDB1 RBX1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DNMT1 RB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CUL4B RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NDUFAB1 NDUFV2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
NDUFAB1 NDUFB6 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
HDAC2 RBBP4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 31435636 21258344 12943729 9885572 34518534 12493763 12091390 21670149 17827154 22939629 16713569 9804427 20388487 27705803 33961781 24981860 11302704 15451426 26344197
HDAC1 MBD2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT3 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A TCP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DNMT1 UHRF1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCT4 CCT8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT5 CCT6A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT8 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT4 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NDUFV1 NDUFV2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBX1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 15136563 11882902 16622419 20871592 11242053 19111658 15960974 16415788 26527279
CBX3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15136563 20871592 20011120 24576085 19111658 16415788 26527279
E2F4 CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 11799066
CBX5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16687578 16622419 20871592 20011120 25281560 26527279 19111658 16415788 19498464
CCAR2 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18235502 22735644 18235501 33459133
RBX1 CUL4B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
RBX1 DDB1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
RBX1 DDB1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10944526 9001254
EP300 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19423655 11689053 16332960
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
MYC IMPDH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18628958 18677108
HDAC3 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
USP7 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 17936559 26460617 15916963 24462112 22056774 18566590 20816748 16402859 20713061 16943424 17380154 29236775 16082221 26238070 34799561 16845383 16474402 28406480 27452404 28196907
DAXX MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 21134643 16845383 15364927 18566590 23405218 18583933 20195357 23038753
MDM2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16374512 21990374 7791904 28615518 33185004 20871633 10078201
MDM2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15195100 12759344 14507915 16713569 12915590
MYC MAOA â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC GPI â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10823814 11274345 11283613 11283614 11704864 16126909 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
E2F4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24573694 17132729 17699159 11689553 12757710
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7739536 10931841 11673469 10657901 12177005 14519204 9111322 9811896 10567564 17706770 24771621 11983916
MYC H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 12695333
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
DVL3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
PML SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 15356634 16189514 18988627
RBBP7 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
RBBP7 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
RBX1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11359933
SIRT1 SUV39H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18004385 19218236
SUV39H1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16409643 19442252 11242053 10949293
TRIM28 SETDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11959841
UHRF1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19798101 22064703 20210320 17673620 24368767 19800870 27049577 20613874 21268065 24782312 26065575 17934516 21045206 21745816 19308066 27045799
KMT5A H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 18166648 15933070 15933069 18418072 18022353 12121615 21983900 15964846 18512960
ESR1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16675542 12746293
NDUFV2 NDUFAB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFAB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFAB1 NDUFV1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFV2 NDUFAB1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFAB1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFAB1 NDUFV1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
COX5A COX5B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX5B â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
SMAD3 S100A4 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
MYOD1 MYOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 21543328 16901893 18676376 12782625 17940050 1581290 12578986 12694204 15870273 1718977 17562853 21892963 22773876 15149596 16858404 20026657 10548518 20466877 11279181 24550007 22710712 17932502 2560751 7852366 11784084 19723804 8119948 15798192 16847330 12101422
CDC73 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 16630820 23331499 21726809 18988627 29774127
MYOD1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 7970718 10373569 10601020 10801445 16936743 12665587 20053773
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
E2F4 H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 11799066
SMAD3 E2F4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12150994
RBL2 E2F4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 22002537 16600870 17671431 9858615 15838517 9121766 11573202 20133863 8657117 17531812 17159899 9144196 12006580 23108140
E2F4 RBL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 12150994 17671431 9858615 7958925 11573202 7958924 18319725 8657117 9724731 9144196 9501179 8643455 10766737 16135806 16360038
SMAD3 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26365427 22908322 25065622 18157133 23243069 20937549 19701891
MTMR4 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20704570 23331499 20061380
SMAD3 RBL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12150994 16189514
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
SMAD3 E2F5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12150994
SMAD3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21986102 10962029 15084595 11331591 10531362
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
MECOM HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11552981 23858473 16713569 11568182
HDAC3 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19442252 16865259
MCM3 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
NDUFB6 NDUFV1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFV2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFV1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFV2 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFV2 NDUFV1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFV2 NDUFV1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
DNMT1 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19454658 32905139 23687305 19109157
RUNX3 RUNX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17488194 15688019 19403666
HDAC4 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22298955 15537544 16613856
DNMT1 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT1 H3-3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT1 H3C2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT1 H3C14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21655924 20946668 17172825 15746193 22975348 12789259 19001520 24058781 23242655 22558281
ESR1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8300756 8912864 8732679 11038749 15831516 15870697 10076999 9626663 18414489
AHR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12612060 17392787 10620335
ESR1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 17641689 15831516 9717844 9841885
H4C6 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
RBBP4 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C2 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C14 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
RBBP4 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3-3B DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H4C6 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C2 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
H3C14 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
AHR CYP2C8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12646173 19365803 16538170 12369894 11913539
RBL2 E2F5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16600870 17531812 11756542 7760804 15838517
MBD1 SETDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15691849 15327775 17066076
MBD1 SETDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15327775 17066076
SETDB1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21243721 11791185 11252719 11959841