Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NR4A2 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11884409 20533997
TP63 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21930790 17935121
CDK1 CBFB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17171635 16407259
CDK1 RUNX2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17171635 16407259
MAPK1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17205132
ELF1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15131122 24104879
TCF3 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19451188 20191379
FLT3 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28522571
MYC CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24704206 26701207
KMT2A CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16997566
RUNX1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16917507 5218981
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
EP300 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24229708 15138260
EP300 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20339243 21467818
HIPK2 EP300 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16917507 5218981
EP300 H3C14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11509556
EP300 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 20089040
EP300 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11896584
FANCD2 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FOXO3 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18268343 0706790105
FOXO3 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20439537 20467422
FOXO3 ABCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18347152
TP63 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9405685 9032395
SMARCA4 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414052
TP53 HIPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217735 15896780
CBFB HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
RUNX1 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
HIPK2 SUMO1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 5217735 15896780
RUNX1 HIPK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16917507 5218981
MAPK1 IER3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16456541 17200115
MAPK1 IER3 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16456541 5218298
TP53 IER3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
RUNX1 IER3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16368886
KAT6A RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16702405 11742995
KAT6A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
FOS MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
NFATC1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19661463 17239241
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
ELF4 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19454702 20802152
MYOD1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10805738 9988769
MAPK1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8941362
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
NFATC2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23858296 22333584
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
MYC HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20388374 19021144
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
SMAD5 NEDD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RUNX1 NFATC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17377532 16873067
NFATC2 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17377532 16873067
NFATC2 FOXP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17377532 16873067
NFATC2 NFATC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19564342 11786533
NFATC2 CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12453415
FOS NFATC2 â—¼   PROXIMITY 2.0 0.8 intact 18172215 0705181105
TP53 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
SUMO1 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
PML ELF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14976184
PML JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671405 10620019
PTPN11 ANGPT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10521483 9764820
PTPN11 SRC â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
PTPN11 KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26617336
SMARCA2 SMARCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10078207 16713569
MYOD1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17194702 17043109
SMARCA4 SMARCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10078207 16713569
SMARCA4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11950834 33476981
SMARCC1 SMARCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1459453 19785031
CARM1 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24434208
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
STUB1 SMAD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 21454478
STUB1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19940151 25637186
H4C6 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SIN3A SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
SUMO1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25704882 22493095
TP53 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11420669 21187340
SUMO1 CTCF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19029252
SUMO1 ELF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16904644
SUMO1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12769861 12679040
SUMO1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19788416
H3C2 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11242053 5213683
SUV39H1 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
SUV39H1 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
SUV39H1 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
DNMT1 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17172825 17584191
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
HDAC3 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16847267 0510834103
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
TP53 BCR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 CDKN2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21900401
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
TP53 HLA-E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1400626 1652755
TP53 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11807984 16567167
TP53 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TP53 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 ABCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10783169
YAP1 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213829 11278685
TP63 CDKN1C â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19089994 16258268
TP63 WWP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18806757 20951678
TP63 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15713654 15781645
NFATC1 TRAF6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17092936 17239241
YAP1 RUNX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10228168 26364597
YAP1 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18701449 18280240
YAP1 SLC9A3R1 â—¼   COLOCALIZATION 2.0 0.8 intact 10562288 5211984
RUNX1 CDK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17431401 5219852
TCF3 CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21788410
CDK6 CCND3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TLE1 CDKN2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KMT2A CDKN2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16997566
JUN SOCS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18571793 17609438
SOCS3 LIFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17312100
HES1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10066785
MYOD1 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10373569
MYOD1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20980337 20037778
SMAD3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11711431
JUN HBZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24336657 15592508
SRC LCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
TGFB1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21358634 9679059
SMAD2 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD2 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15599395 9812998
SMAD3 RUNX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16135801 10531362
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
SMAD3 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21294585 11042172
SMAD3 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11331591 21612856
SMAD3 FOXP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19701891 15367216
HIF1A PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18340011 19648120
DNMT1 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19339266 21229291
BMI1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 19903340 8291464
PTEN BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19903340
TAL1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
HDAC1 GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
HDAC1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20609221 22422937
HDAC1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20037778 19435809
HDAC1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10220385
TAL1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
HDAC2 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
MYB KIT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9416832 16484593
MYB KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11259163
HDAC3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15292260 18321663
HDAC3 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17694085
RUNX1T1 NCOR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18952841 0802696105
MECOM JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1119229109 22308434
HIF1A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15794924 19828020
JUN VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15930183 17121851
JUN RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11604227
JUN RHD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9795199 9121495
JUN BCR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9746785 15145216
JUN PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17138645
ESR1 HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 19039095
HIF1A HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20010940 28602625
HES1 TLE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19250647 16608701
HES1 FLT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25234168
HES1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9108352 18162173
HES1 TLE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24270405 8687460
FOXP3 HLA-E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20554955 24523508
SPI1 HLA-E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22112519 7814871
SPI1 GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
FOS SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9988737
SPI1 ITGA2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9305885
SPI1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9292515 12027437
SPI1 CSF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
SPI1 ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9689920
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
HIF1A CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17382325 5219810
CREBBP GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
NCOR2 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12589049 10612426
CREBBP VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10406465
CREBBP H3C14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11509556
CREBBP H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
HIF1A SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17848618 19016748
HIF1A TPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18473128 15705785
MECOM ANGPT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15889140
SRC FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17160021 22105363
FOXP3 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16785520 24308961
FOXP3 NFATC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20554955 19564342
ETS1 TRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1409722 9780181
ETS1 CD8A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8413295
FOS ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 8557686
ESR1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19797124 20819530
RUNX2 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16476583 22713854
MECOM FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1119229109 22308434
PRMT5 FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOS MECOM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1119229109 22308434
MECOM FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15156182 7929053
FOS NFATC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15073183 23619911
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
KMT2A BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056311 19208841
CDKN1C CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17145710 9106657
RUNX1 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18316480 26010396
GATA1 RUNX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16628190
RUNX1 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16287839 14747476
RUNX1 MECOM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22689058
KMT2A RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23817177 22012064
RUNX1 ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
SOX5 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19664780 24692107
SMAD1 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17215250 22298955
H4C6 DNMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KMT2A FOXC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16199523
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
ESR1 TRPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23031797 18414489
ESR1 ADA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11357058 18414489
EPOR PIK3CG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
ELF1 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10207087 14970218
CBFB PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18316480 26010396
NCOR2 RUNX1T1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24130502 10688654
NCOR2 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16287852 23331499
GATA1 GP1BA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17725493 12724402
RUNX3 CD8A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23018457 14500656
PRMT5 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1209814109 23071334
COPRS PRMT5 â—¼   COLOCALIZATION 2.0 0.8 intact 6543161 18404153
H4C6 PRMT5 â—¼   METHYLATION ✅ 2.0 0.8 intact 1209814109 23071334
MECOM PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
H4C6 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18079182 11448779
WWP1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD5 SOX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
MYB TAL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1259037 25394790
TAL1 CBFA2T3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
TAL1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22897851
TRPS1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16140555
MECOM GATA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15889140
RUNX3 ITGAL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12855590 16164020
VDR ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18602086 19460946
MECOM GATA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15889140
CTCF LYZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10480923 10940558
ELF4 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14769796 10625494
H4C6 DTX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TCF3 MYOD1 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 1649701
FOXO3 TP53 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
EP300 PAX5 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31941781 21357426
NEDD4 NTRK1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25921289 19953087 16701206 27445338 21332718
VDR SMAD3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10037600 11278756
PTEN WWP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 33470109 21532586 25547115
GATA1 SPI1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10364157 12202480
NCOR1 VDR â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
MYC CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
CDK2 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
CTBP1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21102443 15834423 35016035 16122695
EP300 SMAD5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16516194 16613856
MYC CTBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RUNX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC FHL2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
MYC BCR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 32140074
MYC DNMT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC JUN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
MYC NCOR2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
SMAD1 NEDD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15231748 21308777
BMI1 RBM14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
SUMO1 SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17036045 24654937
ETV6 SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12527908 11439334
SMAD3 RUNX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10531362 15897867
JUN HDAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17056544 25609649
IKZF3 HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12015313 30760870
GATA2 SKP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 25670854
SKP1 ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31527615 23770852
FOS ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
PCGF1 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26687479
ESR1 CTBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
RUNX1 CTBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17635584 30585266
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
UXT TRPS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CREBBP FOXO3 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ESR1 STUB1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
CDK1 CDKN1C â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
KRAS MAPK1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CCND3 CDK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 26496610
CCND3 CDK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16782892 33854235 26496610 9716181 33961781 26186194 23455922
PML SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 15356634
CTBP1 RBM14 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31041561 30217970
TRPS1 SUMO1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17391059 23772552
SMAD3 WWP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 25910212 15221015 15359284
BCR KIT â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 8757502 25241761
RUNX1 CBFB â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 17431401 5219852
DNMT1 RUNX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15735013 28533407
CTBP1 TRPS1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31041561 33961781 35016035 26186194
AES SOX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 35140242
CD69 CLDN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
CCND3 CDK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HIPK2 SIAH1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HDAC1 SMAD2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
FOXO3 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19592618 25609649 11896584
EP300 FOS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19064921 21937452 11287611 24069158
HIPK2 PML â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
MYC HIF1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 15071503 28205554
PML FOS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9671405 16189514
ESR1 SUMO1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 15961505
NTRK1 TRAF6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16246731 18457658 25708205
RUNX1 CDK6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17431401 25241761
NCOR1 ETV6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11001911 11439334
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
HDAC2 FOXP3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19276356 25609649
RUNX2 SMAD1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10531362 10962029 17215250 20851880
HDAC2 PML â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
SMARCA4 TP53 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CREBBP TCF3 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ETS1 RUNX1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HES1 TLE1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
BMI1 CBX2 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
DNMT1 HDAC2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
MYOD1 TCF3 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
JUN PML â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CDKN1B CDK1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 34591612
RUNX1 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14752096 16917507
EP300 SMAD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10205054 20851880 22365546 16613856 10673036
MYC HDAC3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23079660 31155734 22002311 18483244
SMAD2 HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10199400 11226163 31130994 14699069
SMAD2 ESR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20207742 11555647
SMAD3 RUNX3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10531362 27497248 15138260
NCOR2 HDAC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30737378 16481466 11013263
HDAC2 HIF1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25241761 11641274
NCOR2 NCOR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16033423 10944117 11013263
HIF1A JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25879517 19738058 11739718
SPI1 JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12091339 9681824
SRC ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 17284441 6169640
ETS1 SRC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25117710 15788656
CDK6 CDKN1B â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 16160006
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
PTEN TP53 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RUNX2 SMAD1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
KMT2A MYB â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
HDAC1 RUNX1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
SMAD1 SMAD6 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
CARM1 CREBBP â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ETS1 PAX5 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CDK2 TP53 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24173284
EP300 RUNX3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24229708 15138260
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
HIPK2 SIAH1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19043406 19250734 23503458 33591310 18536714
SMAD3 NEDD4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19953087 32296183 15496141 21685363
TRAF6 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10635328 16189514 22447928 29545793
HDAC3 ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31527615 16469706 14722073 26487511 20348541
CREBBP ETS1 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
VDR SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20371703 15919723 12796488 12893883 15604093 16434701 21917910
TAL1 RUNX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21179004 19497860
RUNX1 NCOR2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17560331 16042694
CCND3 VDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16105657 21988832
NCOR2 ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9702189 14715875 20392877 12738788 9171229 23403292
ESR1 FHL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15666801 31527615
SMAD5 RUNX2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10531362 22966907
CREBBP TCF12 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
EP300 RUNX2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
JUN MAPK1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ESR1 FOXO3 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CARM1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16923966 18280497 11997499 21988832 11701890 32140074 28844863 15731352
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
ESR1 FOXO3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18312651 11435445
MYC CDK6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22094256 28628118 28205554
MYC HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 22286234 30415952
TRAF6 FHL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16184196 18768464
MYOD1 NCOR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 10406466
HDAC1 UHRF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27743347 15361834 21952639 27114453
SRC KIT â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24728074 12878163 12444928
HDAC3 GATA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 11567998
HDAC3 HIF1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17273746 11641274
NCOR2 FOS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10777532 20195357
BMI1 CBX2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21282530 34316702 20601937 19636380 27705803 22325352 33961781 24981860 24457600
ESR1 TRPS1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23403292 26153859 31527615
NCOR2 VDR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9878542 12460926
AES TLE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 33961781 22354967
AES TLE3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 33961781 24981860
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
NCOR1 RUNX1T1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HIPK2 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PTGS2 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CDK2 SKP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MAPK1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SUMO1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SMARCA2 SMARCA4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMAD2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMAD2 TRIM33 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMAD3 TRIM33 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PTEN SLC9A3R1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HDAC1 RUNX1T1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
RBM14 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11443112 33742100 16713569
EP300 MYB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20364308 11585920 29954426 15691758 35140242 10656693 25740244
EP300 SMAD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11371641 21988832 10199400 12237408 11264182 15623506
EP300 VDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32603375 15647825 20089040 21988832
NCOR2 PML â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11585900 11430826
MYB PML â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15194430 20802522
PML HDAC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11259576
SUMO1 ETV6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24654937 26871637 12626745 11078523
CDK4 CDK6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23455922 28205554 28628118 33961781
SOCS3 EPOR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10882725 12027890
MYOD1 CDK4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10601020 10022835
SMAD2 SMAD1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9111321 28628118 18729074 28205554
FOS SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21829441 9732876
TAL1 HDAC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16407974 19497860
HDAC3 RUNX2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15292260 18321663
SIN3A TAL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10688671 11118214
JUN ETS1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20195357 8557686
JUN RUNX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11641401 11274169
PCGF1 SKP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16943429 26687479 27505670 32628469 27705803 22325352 33961781 24981860
SRC RET â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 33961781 32062451 10070972
FOS RUNX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11641401 11274169
ELF2 RUNX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10207087 14970218
ESR1 BTF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31527615 18025262
SMAD6 CTBP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14645520 24850914
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CTBP1 CTBP2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CBFB RUNX3 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 MYOD1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PML TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
TAL1 TCF12 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CARM1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
DPF2 SMARCA2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CREBBP SMAD3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HDAC2 SMARCA4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CREBBP JUN â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CREBBP SMAD2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CD44 SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21701559 11084024 9519902
EP300 HIPK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16917507 29170424
SMAD3 FOXO3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15084259 24920680 21532621
MYC PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17146439 15735755 21150319 32592588 30415952
MYC SKP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12963825 21988832 17314511 29467282 30415952
MYC CDK4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22094256 28205554 28628118 21988832
GATA2 PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10938104 16189514
PML JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15626733 9671405 16916642 10620019
PML HDAC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25812002 18073335 11259576 18644863
SMAD1 YAP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19914168 21685363
HDAC1 MYOD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11285237 11684023 16713569 20124407
JUN MYOD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8380166 1310896 16713569
SMAD2 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11371641 20195357 10220381 25609649
HIF1A SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 28471448 11486006 14741200
SMAD3 RUNX2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10531362 10962029 21986102
HDAC1 NCOR2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11739383 16481466 11013263
HDAC1 SPI1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14647463 16331260 11593411
HDAC2 CTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17967884 31041561 16713569 28947780 16036112 10766745 18212045 11022042
HDAC2 DNMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23708667 17967891 21670149 10888872
NCOR2 SIN3A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10944117 10640275 11013263
NCOR1 VDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9878542 19098224 11124027 16252006 12460926 10877839
RUNX2 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11641401 11274169
JUN ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17317669 11477071 16713569 23747343
RUNX2 FOS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11641401 11274169
CTBP2 CTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31041561 16189514 25416956 16713569 21988832 28947780 30585266 26496610 33961781 35016035 26186194 24722188 27107012 9858600 26344197
ELF4 RUNX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10207087 14970218
SMAD6 SMAD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11483516 12857866 9436979 9256479
SMAD5 WWP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 16189514 15221015 15231748
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
FOS NFATC2 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CCND3 CDKN1C â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CDK1 CDKN1B â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CDK6 CDKN1B â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CDK4 CDKN2C â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CDK2 CDKN1C â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
DPF2 SMARCC1 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
TAL1 TCF3 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MYC CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22002305 22911891 19738061
CDK1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17477081 23526763 21840486
UHRF2 CDK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21952639 15178429 33876395
CDK2 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26186194 10330164 23455922
CDK2 SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7553852 26496610 25852190 33961781 9636170 23602568 16979657 23455922
HIF1A CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19342889 20138114 19940121
VDR CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16518840 15064717
ESR1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17163418 17681750
KMT2A CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16169901 19318494 19031738
JUN CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10700231 20566634 19959471
EP300 TAL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11756538 11118214 10490830
EP300 MYOD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20364308 12665587 20037778 17964260 35140242 10944526 9862959 9001254 8621548
EP300 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27956703 21268080 21937452 24069158 11689449 14630807 11980644 10327051 12437352 12471036 24636898
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
EP300 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20851880 22298955 12697832
FOXO3 RUNX3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16373335 16738314 12637528
GATA2 FOXO3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
FOXO3 KLF6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18226221
TLE1 GADD45A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IGHM GADD45A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GADD45A TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SUMO1 HIPK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15958389 16253240 21145359 10535925 15896780 21192925 24637324 14609633
HIPK2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 12874272
MYC IER3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12360408
SPI1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22075620 10727414
MAPK1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15967790
MAPK1 GATA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7876160
SMAD2 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11804592 28628118 28205554
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
SMAD1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 15576399 22290435 22761862
MYC UXT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SFRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17485441 20697356
MYC FPGS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC TCF12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
NEDD4 PTEN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19345329 33712741 31469661 29593330 21986318 31578285 25047839 27295432 18498243 24063548 28437168 24141722 18307411 25547115 30594392
NFATC2 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25126782 16517728 17463169
NFATC2 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12453415 11402342 11030334
HDAC1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 11259576 18644863 25812002 11430826 23563092
SUMO1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11948183 16189514 9885291 19015637 21305000 23028697 28851805 23604351 15017387 22155184 21057547 19380586 24190887 20826694 20972456 23830076 17027752 24654937 25497731 9756909 21779164 31879127 17081986 18625722 8806687 17081985 17344210 19217413 17036045 18474224 9452416 20188669 16501610 22406621 22875967 9427741 15561718 21098080 11080164 11160742
NCOR1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11430826 10882117 16713569
TP53 PML â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14992722 18056437 14715247
PML SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15356634
PTPN11 IL22 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15919823 7512451 20671117
CTCF RAD21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19369356 19826084
SMARCC1 SMARCB1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24421395
SUMO1 CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20176810 20098713 12679040
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
SUMO1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18093978
PAX5 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8521821 22105368 21319196
TP53 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16462763 16651407 18431400
TP53 FHL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18615633 11062252 22796152
TP53 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15469934 14586398
TP53 CDKN2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16169070 16713569
TP63 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19861536
TP63 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278685 35044719
SOCS3 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18055217 16543409
FHL2 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18768464 16184196
TRAF6 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18093978
YAP1 RUNX1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18701449 25283809 10228168 18280240
YAP1 RUNX2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31496812 25751140 32220262 27684187 10228168
YAP1 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14765127 22153608 10228168
ESR1 SOCS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055089 18414489
SOCS3 EPOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10882725 12027890
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SMAD2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27974707 11456453 16284942
HDAC1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10199400
SMAD2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18729074 9111321
SMAD3 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10903323 11306568 10220381 9732876 21829441
SMAD3 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
MECOM SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23858473 9665135
SMAD6 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9892110
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
FOXP3 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27861999 20554955 19797626
HES1 DTX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20161710 20208568 16990763
RUNX1 HDAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
HDAC1 CBFB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
CTBP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 9650586 16189514 23752268 31041561 16713569 28947780 10995736 34147029 18765668 11022042
HIF1A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17273746 11641274 16511565 21148070 24015760
SIN3A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15695521 28514442 9520398 10640275 14647463 12398767 9150133 10444591 14593184 21258344 12943729 12374985 17956988 11102443 9885572 17962807 26496610 12453419 11171972 16331260 20585571 10220385 25314079 12091390 11931768 17643391 11602581 17827154 12724404 11784859 23752268 18059533 9790534 9804427 26949739 24981860 33961781 19182791 11118440 15451426 12920132 26344197
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
HDAC1 RUNX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18430739 22274925 18850007
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
GATA2 KIT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20833840 18243117 26660446
KIT PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17496910 7520444
HDAC3 NCOR2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12205093 21624135 10809664 24449765 16924111 10944117 21258344 11509652 26728228 15837933 12628926 11804585 22230954 14527417 16980585 23752268 29523594 12502735 10860984 11013263 16481466 17126328
HDAC3 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16528103 18241676
CBFB SIN3A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
NCOR1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 24051437 12145334 16469706 17400812 12738788 21182203
SPEN NCOR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12897056 16713569 11331609
JUN NTRK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15870692
JUN ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1945412 8247540
JUN TNFAIP6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8454627 7935377
TLE3 HES1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8649374 8001118 8687460
TLE1 HES1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8649374 8001118 8687460
SPI1 GATA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18250304 10364157 10411939
PAX5 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10688639 11179673 21549805
SPI1 CTSK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19288495 15304486
SPI1 CTSG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16019164
SPI1 TAL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16298389
SRC ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24498420 14766010 15604093 11013076 27420286 29720121 12736255 18451880 15140878 23065768 17043237 17627277 7539106 11032808 17363140 20935677 14963108 11564893 12630920 22328528 15020686 15784253 17921256 24051437 10454579 17400812 17284441 16957778
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
SRC KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30644389 26854235 9096340
ETS1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7848925 8999884
TCF3 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15367695 19734904 11509675
TLE1 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17145710 9751710
ESR1 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28539435 18657504 11029009
NCOR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17591692 23015261 15802375
RUNX2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17350616
ESR1 WNT5A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR1 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21737465 21947652 22878616
ESR1 FOXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25303530 18414489
ESR1 ARID5B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR1 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664452 17556531 12710998
MECOM CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11328817 11313276 16713569
KAT6B RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 11965546
GATA1 NFE2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16648487 20564185
MYB CTSG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16019164
CTCF IL19 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
CTCF TNFRSF18 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22951020
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
NEDD4 PTEN â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
SMARCC1 SMARCC2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CCND3 CDK2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
CCND3 CDKN1B â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
TLE1 HDAC1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 19101520 22439931
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CDKN1B CDK4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5219242 17053782
SMARCC1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
SUMO1 JUN â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 10788439 15469925 11867732
TLE1 HES1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 18611861 24270405 19321451 8687460 33961781 19956621
TAL1 GATA1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 7568177 16407974
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
JUN NFATC2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
NCOR2 RUNX1T1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CDK6 CDKN2C â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
EP300 TCF3 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
DNMT1 UHRF2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
FOXP3 SMAD3 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HIPK2 MYB â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 15082531 16055500
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
FOXP3 NFATC2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RUNX1T1 TCF12 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
SMARCB1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
SUMO1 HIF1A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 20026589 15876874 24434214 20661221 15465032 17938407
NCOR2 HDAC3 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24449765
NCOR1 SIN3A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 17210713 11430826 16713569
CDK2 CDKN1B â—¼   PHOSPHORYLATION ✅ - 0.95 0.95 Signor 17409098
CCND3 CDK6 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
PCGF1 SKP1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
HIF1A EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17382325 5219810
HDAC1 TAL1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10688671 16407974 19497860
CREBBP SUMO1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CDKN1B CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 34591612
HIF1A EP300 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15280364 19589782 16543236 11823643 22807441 19666581 16189267 18047470 15342390 12042299 19680224 22735262 23448368 26135796 23618863 14691445 19696166 11959990 27320910 16847340 24821806 22789427 17906695 8917528 20620956 20000859 15261140 16081065 12778114 22219185 15154850 25192544 22075993 19071119 22908229 19940151 21187066 24421387 23880760 11940656 23966271 26826385 26944191 12588875 23746844 11063749 27808477 19074848 20603618 15155277 18268343 20829524 21148070 12914934 17502379 22684029 17382325 26751287
CDK6 CCND3 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8153045 21516116
CDK6 CCND3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 25416956 33854235 14681455 21516116 32296183 17517622 9716181 11360184 30217970 23602568 15232106 26264872 27107012 32707033 16782892 16713569 8114739 29997244 32814053 33961781 26186194
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
HDAC1 DNMT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22274925 20613874 26794444 10615135 10888886 17707923 17934516 15870198 21670149 27593931 17967891 12473678 23708667
SIN3A HDAC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16254079 12398767 21258344 12943729 9885572 9150134 12453419 12493763 14749338 22493095 12082111 25314079 12091390 17827154 12724404 23752268 18059533 9804427 26949739 24981860 15451426 26344197
HDAC3 NCOR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16917504 11466315 10944117 21258344 11509652 16195251 16469706 14722073 15601853 12628926 11931768 11804585 14527417 16980585 23752268 29523594 16713569 10860984 11013263
SMARCA2 SMARCC2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
DPF2 SMARCC2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SMARCA2 SMARCC1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
PML SUMO1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
SMAD1 YAP1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CREBBP MYB â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
CDK4 CCND3 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 8153045 21516116
DPF2 SMARCA4 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
SMARCA2 SMARCB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CREBBP KMT2A â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DPF2 SMARCB1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CDK4 CDKN1B â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
HDAC3 NCOR2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
CCND3 CDK4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 16189514 25416956 21988832 33854235 9106657 14681455 21516116 23880157 16985050 32296183 10342870 26496610 19237555 9716181 11360184 30217970 15232106 14641107 25910212 27107012 16782892 33961781 26186194 11896535
CBFB RUNX2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
CCND3 CDK4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CREBBP HIF1A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CBFB RUNX1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCA4 SMARCC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMARCA4 SMARCC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMARCA4 SMARCB1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCB1 SMARCC2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCB1 SMARCC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDK2 CDKN1B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SPP1 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 21907263 20549562 20146103 8560266 12377945 16713569 10657301
CDK1 GADD45A â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17660363 18414028 18543256 18590585 18995830 19004803 19652693 19686080 23485469 7575488
CDK1 GADD45A â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17660363 18414028 18543256 18590585 18995830 19004803 19652693 19686080 23485469 7575488
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
TP53 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10825186 11593387 12874009 19472317 10514438 11313928 16807237 8270002 17942917 9275177 20395210 11032828 19861536 12889596 19067706
TP63 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11593387 19861536
GADD45A CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18942077 10362260 10973963 12124778 16189514
CDK1 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 25914884 19386523 21059642 17015473 18003885 16046550
CDK1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23455152 23543736 25032860 21490307 16492801 10931950
CDK1 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16407259
CDK1 HMGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 19664994 10636877 19413330 18707149
CDK1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21902831 10942602 17014844 10082583 10764802 9710583 14749395
CDK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 24173284 12767922 1584757 20661218 26029996 2141171 9467949 17570479 20808790 7862459 11327730 11078726 27726420 8357826 16713569 2156209
CDK1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21565170 27220480
MYC CDK2 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
MYC CDK2 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
CDK2 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10197981 11283614 12193595 14536078 15147722 15241418 15279786 16156666 17055429 17303408 17660363 18590585 18636226 20027199 20713526 2191300 28536364 7575488
CDK2 BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
MAPK1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10962581 12359725
SKP1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 7553852 23602568 16979657 9636170 26496610 25852190
CDK2 UHRF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 33876395 21952639 15178429
CDK2 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21565170
CDK2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8386367 27653698 17081983 19966300 18669648 29896817 17570479 20713526 17558397 15103331 22348395 20445224
CDK2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 10197981 15241418 19218245 25241761 15520018 20068231 17099224 16156666 16189514 19413330 14512875 12193595 15212693 19114991
CDK2 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 25914884 17570479 16046550 17015473
CDK2 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 125.0 1.0 Omnipath 26416244 20519948 19631451 16326706 17409098 15557281 9658399 23029392 22733130 17570479 26496610 23576547 12700233 9388487 10585280 27282251 27175940 15619620 25241761 15735731 9218599 9192873 17254966 15996662 9724724 11940657 18285702 22492278 23409140 18615582 12093740 22721951 15647383 9380407 17418410 16189514 17053782 17698606 25852190 10679394 17602833 9660939 12188931 15122251 10831586 25818643 22028818 21424700 12529437 15011833 12042314 11250701 11223033 23455922 8978686 16780593 21439954 15302935 19648963 14504289 9736735 10198259 16782892 11565035 21423803 16492801 9311993 12417722 17671428 21187893 15355997 28601655 10809788 10393546 15212693 10323868 26450989 23602568 18850315 12482975 9399644 15890360 9632134 17254967 26186194 20810788 20197382 15475007 12800980 17997402 12972555 15980415 24336329 26701207 25605247 26987798
CDK2 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21902831 10942602 25751651 25552934 22179841 17570479 10082583 26825227 10764802 9710583
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
CDK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 24173284 9315650 19413330 19664995 16083285 1088347 16552184 10884347 17570479 10747897 25241761 7624134 11687964 17287340 92065884 12064478 19556892 14640983 10348343 14702041
CDK2 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21602882 18769144
FLT3 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10323868 17254966 28522571 19075005
HES1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22311706 19541765 15870295 19598246 19609448
FOXO3 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 21840777 19244250 19911116 17522055 18312651 21752881 22930444 18393360 10783894 15100294 11094066 18593906 18687691 19168439 21249150 14981546 18787071
TP53 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15145945 15988033 19235838 10516009 21478095 14984207 19427386
MAPK1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12042314 9192873 10831586 10931950 12700233 15212693 15735731
CDK6 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16160006 25241761 18615582 16782892 21439954 11360184
TP53 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21340684 20066118 20457558 20182602 6396087
FOXO3 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 14976264 19564415 18644865 19380174 10783894 16288288 20673124 11094066 15930121 21708191 17646672 15084260 15509806 21613825 17940099 11994454 11154281
SKP1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15340381 15147722 12820959 16209941 11516665 15071497 15688063
HIPK2 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24806449 21715331
SRC CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17145710 29899857 28882106 18627125 28522571 21045138 17254967 20519948
CDKN1B CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 23602568 8978686 23707388 21439954 18850315 16326706 9658399 14597415 18615582 10198259 16782892 9632134 16189514 17053782 11360184 9311993 17092340 20837141 26186194 25241761 15695403 9464540 19470470 9106657 10908655 23543736 11940657 18285702
CDKN1B CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14597415 16189514 10342870 16328436
EP300 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12057991 17395887 17237818 12471036
CARM1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15731352 21988832 11997499 11701890 15616592 16923966 18280497
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
DTX1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11564735
EP300 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15965232
EP300 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10944526 9001254
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 21988832 23331499 9169454 12237408 10199400 11264182 7878020 8047140 12958365 19171760 11371641 16027720 17074756 17469772 21269274 15623506
EP300 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19423655 11689053 16332960
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
EP300 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12419246 14500836 10673036 22298955
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
HES1 FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
HES1 FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
HIF1A FOXO3 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
FOXO3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24062311 16807346 16809346 17575143
FOXO3 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11964479 15721278 12048180 18845647 21835778
MAPK1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18204439 29445193 22128155 10102273
FOXO3 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18644865 10783894 16288288 20673124 11094066 17646672 15509806 11994454 11154281
FOXO3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11435445 15367686 16807346 18312651
FOXO3 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14976264 18644865 10783894 16288288 20673124 11094066 17646672 15509806 11994454 11154281
TP53 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10749144 22801474 11221850 15031557 22262183 10321740 17700520 11420680 10094833 23114628 8892753 23948959 9405685 21394211 9931282 10435630 12007564 15721278 17440969 23576563 9566896 9233781 21836608 21245169 15186775 17063488 9154806 10327059 9191059 17344317 9519881 20797428 18350249 7624148 10566557 17084916 16714289 20840860 15735726 12806965 18225552 16581545
MYC GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15721278 9190899 10913183 15021909 14519204 9811446 21835778
TP53 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16990795 15603758 14627995
TP53 HIPK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16343438 19642869 18809579 18483253 19828042 21248071 18336191 11925430 11740489 11532197 17658469
SIAH1 HIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19043406 19788416 9403064 23503458 18536714 19250734 19607803 20682032 21466614
SUMO1 HIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21145359 15896780 10535925 14609633
HIPK2 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 28532298 14567915 23331499 27689990 19788416 22649776 15708980 22889244 23291169
HIPK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19828042 25210797 20508833 22545114 23814485 19731416 11740489 20171273 11875057 16212962 16729035 23700162 23945296 24101931 27308326 16713569 23536002 28107201 27901482 27019364 19714248 22011578 27308327 15896780 16601678 23316480 24145406 28122345 21192925 17906639 25313037 27689990 20849851 21258400 17203463 19128456 17349959 25364713 11925430 20418953 24829283 22935610 21855806 28893313 23717325 11780126 19946469 21057547 23293771 27787517 26942128 15865933 17210684 17332358 22110707 22889244 23091802 24211575
HIPK2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17081983 27689990 27308327 26539288 19015637
TP53 IER3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11844788 12360408
MAPK1 IER3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12356731 16456541
ETS1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 8552081 10358095 20534573 11782450 15572696
MAPK1 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MAPK1 SKP1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
MAPK1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
RET MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 19901323 11522789 91184134 16156666 16497976 15592455 12571246 19415658 11826406 17389395 18578522 21109534 20068231 18452278 18669648 16153436 11522288 18691976 1378617 15972258 15935618 16094384 12388769 11971971 19651622 21842857 28450419 18707149 17016520 21455180
MAPK1 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21494553 21449613 25241761 16045329 23991633 20361728 11570862 22521293 11948414
MAPK1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 8072547 11313929 15378002 12531896 12853483 23720779 9662434 1496019 17570479 1922387 11278277 11739718 16023596 20086174 25557171 7737130 26755651 8224842 14676207 17920329 25201974 9022811 22327296 18650425 8137421 18443042 12881422 18572021 17001009 33767435 7744008 23616010 26745678 14617628 11432833 16819515 22606284 12040039
MAPK1 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
MAPK1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 23331499 10197981 34504019 18775330 20659902 8226933 9620846 16156666 9604935 18988627 12193595 11027280 8388392 27153775 31995604
MAPK1 LIFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 30851421 7777512
MAPK1 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16046550 17015473
MAPK1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 19218245 18032789 18729074 16156666 19914161 23331499 19914168 24080014 8226933 14512875 15520018 20736297 26497676 12193595 26297431 18988627 8388392 10197981 15241418 18775330 9604935 9380693
MAPK1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16954218 10551817 18519666 18687685 26784107
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
MAPK1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22935031 29416846 23293771 23316480 15093545
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 NR4A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17681692
MAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 14965474 9765199 15116093 21675959 23443559 10781582 25241761 10446957 10958792 11409876 11709713 21147777 10673501 11551930 15867353 11875057 12091386
MAPK1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 12134156 20506250 15547943 8248197 7816602 15084594 12697810 8226933 20068231 18452278 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 21098038 9604935 11274345
MAPK1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17289590 19914168 9335504 19914161
MAPK1 TCF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 14592976 12810726
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC TGFB1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
GATA1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24336126 19522008 12832487
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
GATA2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19522008 22951020
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
MYC H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 12695333
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
MYC CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15208653 12835716 24951594 21384303 14519204 22395148 10688915 17728244 11983916 18414489
MYC CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20682794 22395148 12835716
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
TCF3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
SMARCB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10319872 14559996 14964309 19234532
GSK3A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11018017 17081983 2663470 11877389 14563837 8247524 16023596 15150404
KMT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 16510874
MYC SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
MYC CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 11602341 17093053 22094256
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
NEDD4 PTEN â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 17218260 17218261 17996703 18562292 19652529 22679284
NEDD4 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17218261 23331499 21071413 18307411 17218260 18562292 18498243 19345329 19652529 30594392
NFATC2 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23105117 18006811 21871017
NFATC1 NFATC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19915002 18078995 15657420 18299389 16455648 11402342 11030334
SUMO1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22875967 9756909 25497731 17036045 21057547 18931695 19217413 8806687 16189514 17081985 11080164 11948183 9885291 19380586 17344210
PML SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 15356634 16189514 18988627
PML YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19788416 19111660
HLA-E PTPN11 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 22464172 2731048 8478617 9485206 9486650 9655483
KIT PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24728074 22806893 7523381 9528781
SOCS3 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12403768 17138568 11356008 10777583
PTPN11 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18757826 18482983 10698938 17974954 14687660 24632723 20308328
SMARCB1 SMARCA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 18414052 23540691 20506188 8895581 31759698
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
SMARCA4 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 12917342 23540691 9891079 28420882
STUB1 TAL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19406989 17962192
STUB1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 14701756 22298955 23344957 21454478 15761153 15708501
SUMO1 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
CCND3 SUV39H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10385618 9736735 12006580 10498883
CDK6 SUV39H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10385618 9736735 12006580 10498883
CDK4 SUV39H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10385618 9736735 12006580 10498883
SUV39H1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16409643 19442252 11242053 10949293
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
ETS1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12145208 19022222 8649821 10510472
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
TP53 ADA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19861536 14647469 16410722
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
TP53 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 1346476 18234965 8554604 8898977 10745175 19714248 9988237 10029407 11096091 11172607 11920581 17952118 8679460 9112432 11350951 8502478 11483599 7949467
TP53 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11514734 18555006 10953306 14741382 19107228 20124454 8274455 16061648 10448271
TP53 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17530187 19861536
TP53 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10101800 23810988 15661074 7566179 15713654 18084616 9525742 20003326
TP53 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12732139 10618379 22264233 23706820 14514686 8183578 14761612 16138117 18593586 23063463 8119773
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53 SIAH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20181957 20421190 14985507 11852084
TP53 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22957312 15843377 12917634 21637289 17344317 12839924 11545734 18172008 19173293 20554748 19079342 14984207
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
TP53 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21336307 18431400 18339852 12620407 17409411 18172008 17823410 16713569 21518799 21483453
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
TP53 IGFBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7566179 17409411 18431400
TP53 SIAH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12077306 12438652 14985507 15326481
TP53 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21187340 16713569 11687965 21763744
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
TP63 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16462763 22521434 17716971 19622632
TP63 ADA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19861536 16410722
TGFB1 TRAF6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 24132110 24336330 7594497 9865696
TGFB1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18922473 22710166 19010789 16474430 22943793 17934056 20519943 12809600 21900405 11133108 18758450 14557817 15548370 19920116
YAP1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19914168 35044719 23431053 21685363
CDKN2C CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 25910212 8840966 26186194 17353931 27107012 23602568 25416956 25502805 8891723 12370184 31515488 11124804 18394558 32296183 16713569 16915296 8001816
CCND3 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17517622 8114739 26186194 27107012 23602568 10477583 16782892 21516116 25416956 29997244 31515488 32814053 15232106 32296183 11360184 16713569 9716181
CDK6 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 18261462 20478528 25241761 17023045 16046550 17431401 17015473 21059642 15475366 22531928
CDKN2C CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 25910212 21988832 11900540 23455922 17353931 26186194 27107012 23602568 25416956 8891723 31515488 32296183 16915296 8001816
MYF5 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15367664 20978076 14724123 12500905 10101129 14732408
SRC JUP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8081883 14517306 23911551
JUN MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 2167198 19723510 1313772 8120060 8264634 1310896
MYOD1 CDKN1C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16405903 18513743 25005473 22740650 10523650
CREBBP MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10944526 16713569 11463815 9238849 2176177
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
CDK4 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21902831 10022835 10601020
TCF3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9242638 1649701 10915743 9001211 9184158 9050988
NCOR1 SMAD2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD2 NCOR2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
SMAD3 SMAD2 â—¼   PROTEIN_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
TGFB1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
CREBBP SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16751102 18003620 9679056 15750622 17283070 20403362 17074756 15231748
TGFB1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15548370 19010789 10678166 16474430 9311995 23831640 17934056 20519943 24075003 11792802 11133108 21900405 14557817 11278410 19920116 9865696
TRIM33 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 16751102 19135894 18003620
SMAD6 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9256479 21071413 9892110
WWP1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 15221015 15946939 15359284
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
NCOR1 SMAD3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
TGFB1 SMAD3 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
SMAD3 SPP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 NCOR2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
TGFB1 SMAD3 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
SMAD3 SPP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
TGFB1 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
CDK4 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 10197981 12193595 15241418 16156666
SMAD3 SPP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 ETS1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD3 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26553048 27974707 10708950 19214138
SMAD3 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26365427 22908322 25065622 18157133 23243069 20937549 19701891
TRIM33 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16751102 23331499 18003620
CREBBP SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15849193 10497242 15467747 18003620 9679056 15990875 15750622 19589780 17074756 17283070 9679060
CDK4 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 34003249 10197981 15241418 25241761 19920136 15520018 20068231 17099224 16156666 16189514 19413330 14512875 12193595 33051597 19114991
TGFB1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21557273 24899689 24075003 24485922 28756206 32196115
SMAD3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9732876 10220381 11306568 21829441 10903323
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
SMAD3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21986102 10962029 15084595 11331591 10531362
SRC PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 24830552 22891331 12869565 21532586
SLC9A3R1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23118026 16456542 21990315 24012959
PTEN PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
FOS TGFB1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 15067049 15749884 16243976 16327802 16393692 16394015 16413922 16713974 17404308 17485448 19667062 20547845 21372296 21385848 22634314 23390297 23430059 9064320
TGFB1 SRC â—¼   ENZYMATIC_REACTION ✅ 56.0 1.0 ACSN 10671552 11133108 11348595 11476890 11955436 11967263 12051714 12426320 14557817 15001769 15279786 15548370 16039586 16099633 16371504 16474430 16919435 17143292 17303408 17496910 17517963 17660363 17928543 17934056 17936032 18037882 18590585 19010789 19029934 19109155 19171760 19619488 19734908 19920116 20519943 20644162 20705860 21278795 21666923 21900405 22007144 22174153 22203675 22370635 22674073 22703233 23343194 24023259 25572304 25730849 26552706 27216177 7542250 7575488 7594497 8666229
TGFB1 ETS1 â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 7594497 9157999 9335507
KLF6 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16611854 18615188 9837963 19076057
HIF1A TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16896927 17053163 15611046 19211927 21209004 21057546 21055290
JUN TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8058069 16327802 16730810 23437118 8183578 16365456 22429882 23936544 15546613 10843986 16978906 23762330 7521696 8631909 12794825
TLE3 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 NCOR2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 NCOR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 NCOR2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 NCOR1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
MECOM HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11552981 23858473 16713569 11568182
HDAC3 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC3 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC3 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
GATA1 KIT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27858941 20405120 9345037 16024808
SRC KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12878163 7520444 10523831
HDAC3 NCOR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 NCOR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
NCOR2 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11509652 17694085 11804585 22230954 10944117 16924111 17126328 15837933
NCOR1 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11509652 11013263 16195251 11931768 16469706 21258344 17694085 10860984 16917504 10944117 23752268 16713569 14527417 11466315 11804585 12628926 15601853
HDAC3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19442252 16865259
NCOR1 NCOR2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
NCOR1 NCOR2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
NCOR1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20462215 17400812 12392082 10612426
NCOR1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16469706 12738788 12145334 17400812 16713569 21182203
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   PROTEIN_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
JUN MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1527086 8670250 12475180
JUN PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 11901151 16001969 19783677 15238218 23523690 10668496 16007171 12057991 22472290 18294142 16339564 17556653 9830045 9988750 19825968 15994313 15772294 9620167 9686761 15525691 11356200 16256955 11234900 18097055 11980644 9705326 19522015 11278336 18282182 12086396 10811116 20237399
JUN SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15557322 15790955 20339243 21467818 19880446 14990565 16491116 17360982
JUN SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17283046 10411939 9178763 9988737
JUN SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7499226 16798740 23533633 14736735 18216279
JUN ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17283040 10369069 17452336 18213731 12907627 14612525 23678002
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
RUNX2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11641401 11274169
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
GSK3A JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 1846781 24214991 91332050 1516134 1956339 16023596 92065884 1651323
CREBBP JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8028671 10327051 2138276 9659924 9786917 16713569 17296604 8545107 18443043 16055710
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
JUN ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8557686 20195357
JUN CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
JUN SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12393465 10411939 12091339
HES1 CDKN1C â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19541765 22705236 25005473 16899237
SPI1 GATA1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 10734131 10753833 12803886 16283355 16418395 20510871
SPI1 GATA1 â—¼   PROTEIN_INTERACTION 6.0 1.0 ACSN 10734131 10753833 12803886 16283355 16418395 20510871
SPI1 FLT3 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10734131 11672593 11964313 12032143 12803886 12811837 16283355 16418395 20510871
GATA2 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19620289 16254139 19491391 24583263
RUNX1 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23817177 19339695 20972335 24037986 18316480 19208846 17994017 12576332
SPI1 GATA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14559995 10411939 11023493 11001896 20304827
SPI1 ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9689920 8756629 16247445 9192779 14732495
SPI1 CSF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12130514 12958595 10677505 20864248
GATA2 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10411939 10364157 18250304
GATA1 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10411939 10753833 15676205 10364157 12202480
HIF1A CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12542982 20547241 17452336 15907483 19489936 15342390 15184875
CARM1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15731352 11701890 12374746 17043108
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
CREBBP MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8654374 11073948 12196545 16055500 18585056 16799563 23980173 14761981
HIF1A FOXP3 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824
HIF1A PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19106818 16397226 21149600 14507857 16818642 23144021
HIF1A ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12067980 20099200 17452336 19128456 17433259
HIF1A AQP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21612401 9537326
HIF1A ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17615296 9157999 9278421 11708773 16716598 12080085 10403805 16887934 15181457 7539918 12490555 1823643 12829734 13130303 15451019 9746763 8943284 15111329 9159130 11566883 21041997
ANGPT1 TIE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11172728
SRC OCLN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12547828 25377781 12604349 20152177 15782139 16492141 9278444 9592087 24349408 22315516 19017651
SRC RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11713247 17570479 16189514 10070972
SRC SH3GL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23255596 16054026
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
DNMT1 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19454658 32905139 23687305 19109157
FOXP3 TNFRSF18 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18832697 17028180 20113470 15343196
ETS1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9349499 8262053 1722028
ETS1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11483599 9584201 22206665 20392592
VDR SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20713445 7705332 20227497 23644099 7981122 8119880 16195230
ESR1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18234909 11522780 9869301 10428965 12761896
RUNX2 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18410224 19903460 20713445 14506237 19259985 19915614 21455926 23644099 9794229 11331591 16670084 16195230 19649655
MYB SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21190594 18459127
SMAD1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10625647 21467818 19664780 20965237 14672939 21276840
NFATC1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21515435 16909108 11423565 21871017 19748606
FOS PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15772294 11278336 9620167 17556653 12057991 8906578 17440114
VDR IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14963110 23770368 20855290 18212051
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
TAL1 TCF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 8159721 7568177 19497860 21179004 16407974 9824680 9507011
CCND3 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 11896535 25416956 16985050 34591612 21988832 14597415 17517622 16782892 10342870 21516116 23880157 15232106 16189514 11360184 26496610 25910212 26186194 27107012 10477583 19237555 32296183 14641107 9106657 9508775 31515488 9716181
CDK4 RUNX3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19351720
RUNX3 RUNX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17488194 15688019 19403666
CBFB RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 25678665 11179217 14729951 24522927 23333304 20195544 17431401 14752096 11276260 2845103 15331439 10856244 11742995 26598521 22498736
SMAD1 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10692396 17215250 22219353 22072987
SMAD6 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9256479 9335505 9436979 21071413 18988627 11483516 12857866
ESR1 CARM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14631847 12498683 11010967 14675539
CARM1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15345777 15471871 16497732 11751582
DNMT1 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT1 H3-3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT1 H3C2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT1 H3C14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
DNMT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21655924 20946668 17172825 15746193 22975348 12789259 19001520 24058781 23242655 22558281
KMT2A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12453419 20210320 24680668 29897600 31485071 20541251 24235145 20452361
NCOR2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12738788 14715875 9171229 9702189 20392877
KRAS PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9727023 16189514 10542052 21779497
NCOR2 SPEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11331609 15604093 24268649 16713569
PRMT5 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19234465 29227283 15670829 20951943 23071334
PRMT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22231400 20084102 15670829
NFATC1 CTSK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19563866 15304486 19576893 20831919 16680826
SMAD5 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10692396 16436528 22219353
MYB ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8756629 16247445 10233885 9192779 14732495
GATA1 TAL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9786909 1396592 7632958 7678994 8058326
GATA1 GATA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19114560 12432220 20670937 14695898 21853041
TLE1 TLE3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10485845 11934263 9819412 8955148 19460168 15768032 15121853 10831834 11266540 9751710
MYB LYZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7684005 11716756 20524209 17959653 17950008
ELF4 LYZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10400620 15504356 15013761 12151102 14976184 10629860 16904644