Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HIPK3 ZYX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SNCA ELL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 INHA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12861022 12732619
XIAP NTAQ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
NTAQ1 RBBP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NTAQ1 XIAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
H4C6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H4C6 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SEPTIN4 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SEPTIN4 XIAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21949740 21695558
SEPTIN4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AIMP2 PML â—¼   COLOCALIZATION 2.0 0.8 intact 8145365 21285945
UBE2I ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
ATM RBBP8 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RAD54L2 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SIAH1 ATN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TP53BP2 ATXN7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TRIM27 BCL6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CCNT1 NELFA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
TRIM27 CDC23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
FLT3 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28522571
CTNNB1 PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
CTNNB1 GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RARA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10607566 23331499
DAZAP2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DDX41 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT DNALI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DNALI1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
TRAF4 FAM90A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TXN GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RUNX1 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
RUNX1 HIPK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16917507 5218981
SIAH1 HIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
MAP3K5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPF31 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TMEM43 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 25942483 1002142
HTT SDCBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
JUN TXN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12414792
PML JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671405 10620019
LATS2 YAP1 â—¼   PHOSPHORYLATION ✅ - 0.8 0.8 Signor 22658639
STAT3 MYD88 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7567467 12244150
NPM1 SYT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PEG10 ZNF512B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SNCA PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PML STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12506013 16189514
PSMC6 PSMC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16763564 5218720
SIAH1 PUF60 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
YBX1 RBBP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20596676
UBE2K RNF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA SDCBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SIAH1 SLC9A3R2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12421809 5215881
SKP1 YBX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218767 16797541
YAP1 SLC9A3R2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217948 16166090
TRIM27 UBE2K â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
UBE2N UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
ATM RBBP8 â—¼   PHOSPHORYLATION ✅ - 0.8 0.8 Signor 10910365
UB2D1 SIAH1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 18070888 18298843 11389839 19549727 16713569 20181957 16189514
SIAH1 SYUA â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 18065497 18070888 19224863 27334109
SH3R1 SIAH1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 16230351
ATM COM1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 23468639 22544744 10608806 10910365
AFF1 CCNT1 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
ACK1 SIAH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23208506 21988832
SYUA SKP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31167929 31980649
HCFC1 EF1D â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 26344197
EX3L2 SIAH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SIAH1 STAT3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27871173 21988832
ELL2 AFF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21729782 26496610 24367103
NHRF2 SIAH1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16713569 12421809
SEPT4 SYUA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17893145 32814053 12695511
SIAH1 DLDH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
JSPR1 SIAH1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SIAH1 PRR20 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 25416956 32296183 33961781
HIPK2 UBE2I â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
SKP1 UBE2D2 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
RLIM UBE2D2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
AXIN2 CTNNB1 â—¼   DOWN_REGULATES ✅ - 0.83 0.83 Signor 11940574
HIPK2 SIAH1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CTNNB1 SIAH1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
RLIM UBE2D1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HIPK2 PML â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SIAH1 COM1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 14654780 26387952
KLF10 SIAH1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12072443 25728284
AXIN2 APC â—¼   PHYSICAL_INTERACTION ✅ + 0.84 0.84 Signor 10911903
HIF1AN NOTCH1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
HIF1AN TP53BP2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
JUN PML â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
SIAH1 SNCA â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
EF1D SIAH1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25416956 21988832 21633900
SIAH1 MARE3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19696028 32296183
SIAH1 PHC2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25416956 20471960 21988832 21516116
TP53BP2 TP73 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
PSMC5 RARA â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
XIAP UB2D2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29020630 12525502 27569044 25801170 19549727 21113135 23259674 11724934
SIAH1 UB2D2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19549727 18536714 19224863 33591310 19690564
SNCAP SIAH1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15064394 14506261
AFF4 AFF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21729782 20153263
DISC1 AIMP2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29961565 32296183
BCL6 TRIB3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16147992 32296183
MYD88 SIAH1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32117091 21988832
SIAH1 PEG3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10681424 16713569
CACYBP CTNNB1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
SIAH1 UBE2D3 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
SIAH1 UBE2D1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CTNNB1 TBL1X â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
TRIM8 UBE2D1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
ELL2 AFF4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 32296183 26496610 22483617 21729782 26186194 28514442
PEG10 SIAH1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25416956 12810624
UBE2D1 XIAP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
RLIM UBE2E2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CTNNB1 SKP1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
TRIM8 UBE2D4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PML RARA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RNF2 UBE2D3 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
NHRF2 YAP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 16166090 27173435 25796446 24255178 30472188
RARA BAG1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9642262 16713569 16189514
YAP1 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 22234184 8383887
HCFC1 HCFC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 24981860 15199122
JUN RUNX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11274169 11641401
JUN STAT3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10490649 16713569
MYB PML â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20802522 15194430
SIAH1 PIAS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17533377 27485016
STAT3 PML â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 12506013
TBL1X SIAH1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16713569 11389839
AFF4 ELL2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CACYBP SKP1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
UBE2D2 XIAP â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CDKN1B COPS5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
SEPT4 XIAP â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
TP53BP2 YAP1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CTNNB1 YAP1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
XIAP UB2D1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29678905 15749826 32296183 12525502 22825849 19549727 21113135 24975362 22304967 15300255 17318174
CCNT1 PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28555140 12727882
SIAH1 DCC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31413325 9858595 16713569
PML JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10620019 16916642 9671405 15626733
RARA PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 1311253 10882117 11050004 16189514 16540467 20159610 12935927 16713569 10610177 18073335 17560333
SNCA SNCAIP â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
TP73 YAP1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
PIAS3 STAT3 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
UBE2D2 UBE2K â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
SNCAP SYUA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10319874 16365047 14645218 15894486 25861987 12044636 11742726 16595633 11331421 19762560 15944382
SIAH1 APC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11389840 25241761 16713569
AXIN2 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10966653 10911903 9554852
ATM TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15838517 15494392 15140942
SIAH1 BAG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9582267 16189514 16713569 12421809
CDKN1B TFDP1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
JUN CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10700231 20566634 19959471
STAT3 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20830236
YAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23607968 22234184 23245941
SNCA GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YAP1 LATS2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17974916 21832154 21205866
NUMB SIAH1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21988832 11752454 16713569 16189514
SIAH1 NUMB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11752454 16713569
PML UBE2I â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
YAP1 RUNX1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18701449 18280240 10228168 25283809
SIAH1 SNCAIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16174773 15064394 14506261
UBE2L6 UBE2N â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16112642 16428300 16122702
HIPK2 MYB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 15082531 16055500
TRIM23 UBE2D2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CTNNB1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 36950384
PIAS2 UBE2I â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
PIAS1 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
AXIN2 CTNNB1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
UBE2I UBE2K â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
AFF4 CCNT1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PHC2 RNF2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CACYBP SIAH1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
DCC NTN1 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
LATS2 YAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMC5 PSMC6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
APC CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
H4C6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
SEPTIN4 XIAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15029247 28224479 21869827
APC JUN â—¼   PHYSICAL_INTERACTION 33.0 1.0 ACSN 11274345 11955436 11967263 12051714 12711682 15001769 15327769 15834423 16039586 16510874 16547505 16940750 17143292 17439715 17936032 19216735 19506021 19619488 19623618 19751508 20006983 20705860 20964627 21285352 21681822 22270359 23343194 24023259 25730849 26587781 7542250 8545107 8666229
APC JUN â—¼   SHARES_COMPLEX 33.0 1.0 ACSN 11274345 11955436 11967263 12051714 12711682 15001769 15327769 15834423 16039586 16510874 16547505 16940750 17143292 17439715 17936032 19216735 19506021 19619488 19623618 19751508 20006983 20705860 20964627 21285352 21681822 22270359 23343194 24023259 25730849 26587781 7542250 8545107 8666229
APC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 10545404 11166179 8259519 7890674 22083140 27902311 8638126 16212417 16798748 19061640 9286858 15327769 9482734 11533658 22056988 19576224 15327768 17318191 26496610 12628243 15355978 9065403 11712088 25241761 26910375 22682247 9065401 12000790 11707392 20219694 9707618 23840886 15525529 11251183 8628279 19631635 11972058 21664290
ATM TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16223874 17525332 15314656
ATM HIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19788416 17332358
ATM RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 23468639 23675572 17570479 24837676 10910365 16249056 11689934 10608806 17525332 22743550
ATM SIAH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 27689990 15964794 11877377 17303408 19788416 16163361 27308327 23847781 18536714 12607003 15459660
ATM ZNF148 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17560543
CTNNB1 AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24447505 15473860 11809809 22615875 11809808 12711682 11940574
CTNNB1 AXIN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10966653 19751508 7542250 8666229 17143292 11955436 11967263 23343194 22270359 9554852 22699938 16039586 16940750 9566905 19619488 15766563 12051714
FLT3 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10323868 17254966 28522571 19075005
HIPK2 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24806449 21715331
SKP1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15340381 15147722 12820959 16209941 11516665 15071497 15688063
COPS5 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17145710 22350412 15688030 18926707 24671224 12082530 18202760
COPS5 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25609649 20093369 18926707 10766246 16713569 8837781
CTNNB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20300972 19671687 16007074 9990071
PKD1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11274246 26764245 11113628 22511927
SIAH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 28481365 11389840 32671611
FLT3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17496910 22558232 17851558 12040186 19568798 22126602 14585353
JUN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17146436 18347071 16007074
TBL1X CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11389839 25241761 20181957 33054136 18193033
NTN1 DCC â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11248093 11989976 17613518 17959595 19543238 19931333 20173780 20495383 22920895 26618107 9765224
NTN1 DCC â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11248093 11989976 17613518 17959595 19543238 19931333 20173780 20495383 22920895 26618107 9765224
NTN1 DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19721007 8861902 26190107 9950216 11239160 25881791 10399920 12810718
FLT3 STAT3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10477595 14670306 15253381 16418395 25215878 8920882 9268501
MYD88 FLT3 â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
SIAH1 HIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19043406 19788416 9403064 23503458 18536714 19250734 19607803 20682032 21466614
HIPK2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17081983 27689990 27308327 26539288 19015637
JUN MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1527086 8670250 12475180
UBE2I JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11877416 16713569 16055711 10788439 8733011
LATS2 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 36.0 1.0 Omnipath 22863277 20048001 18413746 24525530 15302935 19797269 17974916 18640976 18369314 29179447 18669648 25670202 26578655 29680477 18565851 21233212 21041410 18158288 19919647 18220336 21832154 22658639 21041411 24976283 26598551
MAP3K5 TXN â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 11274345 12556535 12655147 18792398 20414655
TXN MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 19018770 25098452 12089063 34837535 10843682 17331951 20385180 9564042 23291592 19880523 21771788 19805025 11689443 15696199 12077134 17724081
UBE2I MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11779867 16713569 22910413
NGFR XIAP â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NOTCH1 SKP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11585921 15546612 11461910 18094723
NOTCH1 NUMB â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 23343194 24023259 25730849 7542250 8666229
NOTCH1 NUMB â—¼   DOWN_REGULATES ✅ - 21.0 1.0 ACSN 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 23343194 24023259 25730849 7542250 8666229
NUMB NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12682059 15358736 16713569 8755477
NUMBL NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9169836
NPM1 SKP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22955283 31434245 16009132 12748172
PIAS3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 11709556 21988832 23331499 12804609 9388184 18037959 15138572 11429412 11266437 20516148 9724754 16189514 19569236
PML YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19788416 19111660
RET STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10918587 9305919 8272872 12626508 15592455 24662939 23331499 17209045 12576423 11350938 18498667 11294897 12244095 16189514 25047660 17761947 9083098 25241761 12637586 8626374 15485908 9566874 11940572 11429593 14551213 11536047 11850821 15212693 9582023
XIAP SEPT4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 15029247 17435549 22733138 23070005 26587781
TP73 TP53BP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11684014 18676979 14729977 18275817
YAP1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 15678106 17110958 35044719 19111660 19788416 21808241 18280240 18640976 25283809 15893728 11278685 17889669 27292796
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368