Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H1-2 CNTRL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-2 TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AMOT WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21205866 23431053
FGFR1 AMOTL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21937427
YWHAZ ANXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
BCL2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1R2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1CA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UTP14A APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NAE1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53BP2 ATXN7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
MAPK1 BCL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217079 15225643
MAPK1 BCL2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217079 15225643
NFKB1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704864 11313951
PLEC BECN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22081109 8303868
BECN1 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810452105 19050071
RELA BECN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19289499 19458474
CCDC85B UTP14A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
TP63 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22777354 23837456
TP73 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11309270 22842668
CENPJ YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16516142 8007368
CENPJ CEP135 â—¼   COLOCALIZATION 2.0 0.8 intact 20531387 7994481
CRK TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
TP53 CSNK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CTNNB1 PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
CTNNB1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 WWTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8383887 22234184
GLI1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19329935 19930158
E2F1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14706452 18794899
E2F1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18396012
E2F1 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24076372 18439978
E2F1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9368006
E2F1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19303924
TP53 E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20428827
E2F3 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18439978 16909110
E2F3 TP53BP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592436 15731768
EEF1A1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
EEF1A1 TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 EEF1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP73 EP300 â—¼   ACETYLATION ✅ 2.0 0.8 intact 11804596 5215037
EP300 RELA â—¼   ACETYLATION ✅ 2.0 0.8 intact 5214468 11533489
HIF1AN EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12573436
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
YWHAB FRMD6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
FRMD6 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
NFKB1 HIF1AN â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 17003112 0606877103
HSPA4 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ HSPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TP73 ITCH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15678106 5217499
KIF5A TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MRPL20 TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NINL UTP14A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PARD3 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22653443 8415349
PARD3 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PRKCI PARD6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213720 11257119
YWHAZ PCM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PLEC TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP63 PLEC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28595999
PLK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 7266226 19833129
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PPP1R14A PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15124925
PTN TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RELA RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RASSF8 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18812399 8008642
TP53 TP53I3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15067011
YWHAZ TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
UTP14A TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UNC119 TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
USP4 TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UNC119 TP53I3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YAP1 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213829 11278685
TP73 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19815500 0905867106
YWHAZ WWTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213315 11118213
YWHAG YAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
APC2 CTNNB1 â—¼   RELOCALIZATION ✅ - 0.8 0.8 Signor 10980707
FGFR1 CRK â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 10464310 25241761
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 22013068 12960163 14662860 12471036 23811396 11739381 20065107
PARD6A PARD3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5213720 11257119
PARD3 AMOT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16678097 34079125
YAP1 CPVL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26933062 24366813
RB1 E2F3 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5219804 17380128
RAN RBM39 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28302793 22939629
PPP1CA RB1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
WWTR1 AMOT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26186194 20972459
PCM1 CEP97 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24421332 26638075 34079125
YWHAG FRMD6 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217174 15324660
NIN PCM1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30217970 26638075 28718761 34079125
PPP1R2 PPP1CC â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 8286865 10807923 003082200
CTNNB1 SIAH1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
E2F1 E2F3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 35140242 24981860 20106982
EP300 RAN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33742100 12649209
PCM1 PLK1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23345402 26638075 34079125
YWHAZ YAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5217040 15161933
YWHAB YAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 8008024 17974916 1602907
FRMD6 RASSF8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ITCH TP73 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HIF1AN TP53BP2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
NUP153 RAN â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
MED4 AMOT â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 25416956 32296183 25281560
GLI1 ITCH â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20818436 31278361
TP53BP2 PPP1CC â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 21998301 270751 8217559
TP53BP2 TP73 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
E2F1 EP300 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
BECN1 NEDD4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21936852 29251248 28128446
TP53BP2 PPP1CA â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5217094 15231748
YAP1 YWHAB â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
BCL2 BCL2L1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PCM1 CENPJ â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26496610 26638075 34079125
OFD1 PCM1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24089205 26496610 26638075 34079125
SIAH1 SIAH2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
PARD3 RASSF8 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AMOTL2 YAP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 TP73 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ITCH TP63 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MAPK1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BAX BCL2L2 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
YWHAE YWHAG â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
YWHAE YWHAH â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
AMOT NIN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19615732 34079125
PLK1 CEP97 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32707033 25659891 19596235
YAP1 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 22234184 8383887
MED4 PCM1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26638075 25281560 34079125
PLK1 NINL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26638075 12852856 28718761
PLK1 OFD1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21988832 26638075
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
TP53BP2 YAP1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAE â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
AMOT YAP1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
BCL2 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CTNNB1 YAP1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
TP73 YAP1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
ANXA1 UNC119 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
APP NAE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25568892 16189514 8626687
BECN1 BCL2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32820146 20889974 19347031 31410188 32097085 23822101 29849149 19959994 19180116 23504944 23541952 25891078 25984893 22498477 31696776 28682313 28431397 21543763 23479509 23316280 24879154 17446862 16713569 18641390 22082873 24034250 9765397 20577262 22241963 28128446 29079782 29955058 24599950 21971985 23564079 20711182 16179260 23168911 24141421 23954414 27304906 22622204 21358617 21139567 20622903 20010695 24472739 19050071 33977871
CTNNB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17404573 16288908 12782598
E2F1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11559537 18319725 11704823
PPP1CC BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 17274640 12051739
TP53BP2 BCL2L1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BCL2L1 PTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BCL2L1 PPHLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BCL2L2 TP53BP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 708717200 7216004 18448430
TP53 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15383401 20332115 21478913
CEP135 CENPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23511974 20531387
TP53BP2 CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CSNK2B UTP14A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23607968 22234184 23245941
E2F1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24755270
E2F1 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19303924
E2F1 SIAH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20187294 18627426
EP300 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10753885 15123636 15126619
E2F3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
E2F1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19276347 21625432
E2F3 TP73 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15210709
TP53 EEF1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23799104 9269753 18431400
FGFR1 NEDD4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19953087 21765395 25292214
YWHAE GLI1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8009500 038232 19996099
MAPK1 YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK8IP2 TP53BP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK8IP2 UNC119 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53BP2 NAE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12694406 16713569 8626687
PLK1 TP53BP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PLK1 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 18477460 22641346 22365832
TP53BP2 PPHLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP1R2 PPP1CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8286865 003082200 10807923
PPP1CA TP53BP2 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PPP1CC TP53BP2 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53BP2 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 21513714 8152471
TP73 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16413471 21436470 18026135
TP73 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11238924 19815500 10373484
TP63 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278685 35044719
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
E2F3 RB1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
BCL2L1 BECN1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
RASSF8 TP53BP2 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
BAX BCL2L1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CENPJ CEP152 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
YAP1 YWHAZ â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
EP300 RELA â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
PPP1CB PPP1R2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
RPGRIP1 RPGRIP1L â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
APC2 CTNNB1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
PPP1CA PPP1R2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
BCL2 BECN1 â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 8095158 21139567
PPP1CC YWHAZ â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PPP1CC PPP1R2 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
PPP1CC PPP1R7 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PPP1CB PPP1R7 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PPP1CA PPP1R7 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
PARD3 PARD6A â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
RB1 E2F1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5219804 17380128
PARD3 PARD6B â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PARD6B PRKCI â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PARD6A PRKCI â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
BCL2L1 TP53 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TP53 TP53BP2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
BAX BCL2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
NUTF2 RAN â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PARD3 PRKCI â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
AMOT YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 32755583 21205866 26269582 21808241
APC2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 23840886 10021369 8638126 16510875 10980707 10074433 9823329
BCL2 BAX â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
NFKB1 BAX â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 12676992 15613549 21725609 23178297 23572150 7834749
TP73 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18034190 17346710 18421303 21245298 10559267 18418051 18644986 17521288 19067706 11748232
TP53 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11278953 12203124 16931621 9582019 17693666 11118038 12433990 11395510 8183578 11429705 10400708 15242522 11423991 19067706 24336083 18381427 22732402 15988033 16341121 10935506 10094833 16215989 17280505 10744634 12851404 20673369 15851483 8845569 10559267 12168779 11850816 19505426 8564971 11756653 19054058 15566940 12173040 17690113 8635454 18034190 10510469 10101800 11335718 23100276 9400998 9445173 9582400 24098340 22532570 9122197 11420692 11104574 15679092 11748232 12560513 11928223 20400479 20546728 17145718 20567883 20840522 18172861 10566557 10777477 7834749 12806965 17521288 19242108 9000137 21859835
RELA BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18034190 18158998 20056115
E2F1 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9748148 11095619 12370749 14514686 15255934
BCL2 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 22705850 18981409 9463381 21458670 17097560 17525735 8358790 10620799 26004684 29749471 9388232 21199865 17525161 22262057 21778226 15486085 17289999 9111042 12419244 9194558 15231068 10716992 8183370 14980220 9115213 21671007 16642033 23479509 10677502
BCL2L1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 59.0 1.0 Omnipath 22705850 18981409 21458670 28202514 11283018 17525735 29749471 21567405 9388232 18547146 19074440 16151013 21199865 18178565 26496610 16189514 15486085 26186194 17289999 9111042 12419244 25241761 14963330 12853473 9742125 9153240 19427863 21852238 14766748 21671007 15131699 9670005 8596636 24814347 9824152 9027312
TP53 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14963330 16151013 7834749
BCL2L2 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18981409 17289999 18178565 21199865 17452531
BCL2 BECN1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10604474 11704864 16179260 17106237 17446862 17891140 18612260 22039431 22885520 23064052 23377657 23430059 23850759 27754749 8929532 9765397
BCL2 BECN1 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 10604474 11704864 16179260 17106237 17446862 17891140 18612260 22039431 22885520 23064052 23377657 23430059 23850759 27754749 8929532 9765397
NFKB1 BCL2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11313951 11704864 21725609 23178297 23572150
GLI1 BCL2 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11001584 11960000 12138125 14555646 15087129 15520176 16054035 16158046 16328026 16396903 16406505 16571352 16880536 17000779 17035233 17638910 18754008 18813803 19081070 19190345 19219074 19736394 20107231 21059263 21442356 22354771 23031257
E2F1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17404573 11559537 12679318
TP53 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 17693666 8183578 10037739 16738310 18397889 19521340 18487508 21666495 16294215 21656028 22869582 19714248 10744634 8174112 17592775 11782367 19137013 20428827 18682598 11713302 11313951 20501806 9649502 24814047 15767042 24098340 11193470 10329733 21859835 22266868 10953306 19555669 23638218 14684736 19411072 20530667 24155778 8205530 20840522 9000137 15326476
NFKB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 16254192 11567031 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 12032828 19233129 16022909 18761399 18987666 15934930 21224428 16453001
RELA BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 19233129 16022909 18761399 18191642 21224428 16453001
GLI1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19074837 15520176 19736394 21940310 24739390 21135115 14555646
BCL2L1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18835031 14980220 26186194 11583631
MAPK1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9115213 10567572 12039864 10669763 15225643 11323415 21785723 9738012 11337027 10677502 23272207
TP53 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12667443 19555669 8205530 19007744 11313951
BCL2 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 72.0 1.0 Omnipath 23504944 17643073 23168911 21971985 19273585 16713569 19050071 16179260 23316280 22205736 23115300 18641390 28128446 17446862 23954414 22241963 23541952 29955058 25891078 29849149 24034250 24599950 9765397 25984893 21358617 18570871 16799551 19180116 20889974 20622903 23564079 19959994 20711182 23479509 19347031 20010695 21543763 22622204 24472739 17438366
RELA BCL2L1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15079071 15536066 17550372 19171876 23430059 8383323 9743347
NFKB1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10925251 17673602 12176906 11992002 14978135 15231833 14739605 10585435 20066113 16904634 9439816 18222423 10733571 15756023 15986355 12226754 15856023 16453001 11756417 18223231
TP53 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22869582 9582400 9989972 11713584 18172861 23519249 12705879 9000137 11713302
RELA BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10925251 17673602 14978135 20585448 15231833 14739605 10585435 20066113 16904634 9439816 10733571 15756023 15986355 21722408 12226754 15856023 16453001 18223231 19706766
NFKB1 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10428780 19211554 10435632 10428030 11756417
TP53 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 24814347 12667443 16151013 26556313 14963330 16713569 20837658 24474649 21900206
BCL2L1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 24814347 12667443 16151013 26556313 14963330 16713569 20837658 24474649 21900206
BCL2L1 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 33931087 19180116 19049976 22219388 18628207 18641390 17659302 9765397 16713569 19713971 24443581 17446862 17337444
NFKB1 BECN1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 19289499 21725609 23178297 23572150
CSNK2B CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10837139 20976471 20558317 10671551 17374729 21285348 11972058 21506126 11689703 10747897 16707567
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
CSNK2B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12432063
CSNK2B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10606744 11709713 10214938 10951572 16713569 11551930 10747897 10673501 11883897
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
FGFR1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17496910 25241761 22558232 11401320 12040186 19568798 14585353
SIAH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 28481365 11389840 32671611
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
E2F1 RB1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
E2F1 RB1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
E2F3 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14576826 7958836 12063292
TP53 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21715977 20805247 8557038 11795482 17210690 22952705
E2F1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11533237 16081466 16738312 16188218 15618023 14681231 16230367 15985428 8264596 18583990 16601104 14627987 15016799 11268000 10490838 11818069
E2F1 TP53BP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19610065 15592436 15731768 15706352
E2F1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22241525 8557038 15706352 21441950 12675512 23954287 12625370
E2F1 TP73 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12766778 11101847 11988839 14602923 18660752 19188449 18029729 18521084 15210709 11115495 17980704 19363520 12789260 21310950 22952705
RB1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 90.0 1.0 Omnipath 17145710 23472054 12502741 22078878 8896460 12397079 9315635 20839231 16249186 11839806 8255752 11713253 20871633 15837424 8346196 19249677 16360038 8626527 12096339 15485814 16374512 18391203 9125176 16766265 9468140 8816798 12598654 10393912 9400991 9632788 12947005 19477924 15485920 17380128 10523633 10869426 7828850 18216119 8657117 12963846 25257171 17488475 28074012 15670817 11583618 7739537 10499802 8413249 11090181 8230483 22768064 29521627 10207050 9553123 7958924 11420730 23001041 16496386 9501179 19058874 1388726 9422723
E2F1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22480684 11739724 12625370
E2F1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15210709 11988839 17488475 11937641
NFKB1 E2F3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 14627988 21725609 23178297 23572150
E2F3 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19015245 9711036 24287699 16449662
RB1 E2F3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17380128 8657117 17488475 10779361 7739537 8832394
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
EP300 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19608861 25400040 11567019 12419806 17617622 11533489 20333651 12456660 15152190 16846590 9096323 20064247 16382138 16713569 15171256 16135789
EP300 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 11804596 19407812 15175157 19788416 12660246 19218448 10648616 15454570 16998810 25675294 15893728 18663001
EP300 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15965232
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
FGFR1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
TP53 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22466965 18811981 16557594 24492005
MAPK1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27342992 23405013
ITCH GLI1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10940313 11318614 16469705 16861923 17115028 17312394 18552861 18628966 20818436 20940030 21107885 21383157
ITCH GLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18552861 17115028 20818436 20940030 17312394
ITCH YAP1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10940313 11318614 16469705 16861923 18552861 18628966 21107885 21383157
ITCH TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 16861923 23370280 16908849 25485500 20855944 22935697
ITCH TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15678106 11318614 10940313 17110958 17592138 21107885 19788416 21383157 18628966 16861923 11278685
MAPK1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15073167 16888388 16691505
MAPK1 TP53BP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22028470 24312625
MAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 14965474 9765199 15116093 21675959 23443559 10781582 25241761 10446957 10958792 11409876 11709713 21147777 10673501 11551930 15867353 11875057 12091386
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
PLK1 NINL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12852856 26638075
PRKCI PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 14676191 22579248 27554858
TP53 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17172872 17981789 15024021 22405092 20962589 24076372 23948487 15016801 22184120 19713933 16369493 23474762
PLK1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20805321 16930555
PLK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22653443 19833129 16753148 23948487
PLK1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18418051 23948487 18174154 22084676
PPP1R2 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 22321011 26186194 28330616 20826336 27173435 18250156 10807923
PPP1CA RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 12202491 8380224 17274640 10773440 9315635 17008050 20694007 8384581 16189514 8380637 10889204 12434308
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
YWHAB PPP1CB â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
PPP1CB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16501611 15178317
YWHAB PPP1CC â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
PPP1CC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17274640 15178317 16501611
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
RELA TP53BP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18448430 16713569 10498867
TP53 SIAH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20181957 20421190 14985507 11852084
TP53 SIAH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12077306 12438652 14985507 15326481
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53 TP53I3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10321740 10101800 12851404 14695213 15192123
TP53BP2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 14985081 16139958 8875926 25502805 8016121 21513714 31515488 16713569 8668206 18275817 11839776
TP53 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11238924 18431400 21508668 9891077
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
TP73 TP53BP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11684014 18676979 14729977 18275817
YAP1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 15678106 17110958 35044719 19111660 19788416 21808241 18280240 18640976 25283809 15893728 11278685 17889669 27292796
YAP1 WWTR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338
YWHAE YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAB YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAH YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAG YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAE YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
TP53 BAX â—¼   KO_DOWN_REGULATES ✅ - -1.43 1.42 PKG 28854368