Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 BMP8B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CTNNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
ABL1 CTNNA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
ABL1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11753601 9916993
AURKA AJUBA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15630414
DVL2 APC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7890890 20224554
APC YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TP53 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
DVL1 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20224554 10330181
BAG5 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CTCF BBC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20818159
CDH1 CCND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0913813107 20439707
CCND1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16461912 0506281103
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
EZH2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132185 21697275
CTCF CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18625744
RASSF1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12024041
LONP1 CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PPP5C CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
CDC37 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
AURKA CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
HRAS CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDKN1A CCND3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
AR CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10076995
TGFB1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23741479 12058028
CHEK1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20639859 8010047
CHEK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5218401 16511572
CHEK2 MDM2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15862297 5217705
PPP5C CSNK1E â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0604138103 16790549
DVL2 CSNK1E â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CSNK1E YWHAH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7264069 19860830
CSNK1E CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20940130
DNAJA3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DNAJA3 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
DNAJB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DNAJC7 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAE DYRK1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217192 15369779
AR FKBP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15131019
SRC HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16844778 0604705103
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAZ HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSP90AA1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0908908106 19805354
DLG4 LZTS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
RASSF1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18566590
MYC TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
AR NEDD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 18703514
HRAS PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
PRKDC MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PRKDC YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
STUB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STUB1 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
TP53 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18812399 8008642
TP53 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
TP53 BTRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19196987 0812256106
TP53 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
AURKA TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14702041 19121998
TP53 PPP1R13B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15090446 15731768
IKBKB TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19196987 0812256106
TP53 GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216887 14744935
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
PPP1R13B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16139958
XPO1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17268548 17891139
TP53 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16917513
TP53 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17015431
TP53 ID2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16557594
TP53 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
YWHAG YAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
LATS2 YAP1 â—¼   PHOSPHORYLATION ✅ - 0.8 0.8 Signor 22658639
FBXW11 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22017875 21900206
CTNNA1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23949920 23431053
YAP1 TEAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11358867 23431053
YWHAZ CAD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CAD MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CTNNB1 FZD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12095419 15473860
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
ACTG1 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ACTG1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
AR AREG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23415714 20610535
CCND3 AREG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11469683 16713569
YWHAG ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ID1 ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9779825 19896442
CTNNB1 ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11572874 12095419
CDH1 TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TGFBR2 AK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12695509 5216326
FNTA HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24294527 2217184
GSK3B AXIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
FZD5 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10428961 8666229
FZD4 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27096005 19388021
FZD2 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23151663 19388021
FZD3 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22944199 19388021
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
AURKB BIRC5 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19357306 0900833106
BIRC5 AURKA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19357306 0900833106
PRKACA CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
DVL2 PARD6A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23151663 19379695
WNT10B FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19008118 12055200
SRC F2R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
FOXP3 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23201402 20554955
YWHAZ WWTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213315 11118213
TEAD3 WWTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19324876 19324877
CTNNB1 WWTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8383887 22234184
WWTR1 TEAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
WWTR1 LATS2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21205866 18227151
AMOT WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21205866 23431053
GLI2 BMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19103752 16880529
GLI2 BMP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18710724 20934421
BTRC AURKA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17939994 0706493104
IKBKB AURKA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17939994 0706493104
LONP1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
HSP90AB1 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IKBKB MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TNIP3 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SEC16A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DLG4 DLG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
MAP3K2 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
FRMD6 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG HAX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAG MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAE MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP3K2 YWHAE â—¼   COLOCALIZATION 2.0 0.8 intact 9452471 5221876
AR LATS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15131260 20610535
MOB1A LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
MOB1B LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
MOB1A LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
MOB1B LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
STK26 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK25 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2R1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2R1A MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PRKACA AK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSK3B CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
GSK3B APC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10698523
XPO1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19940019 18573912
CTNNB1 CTNNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
CTNNB1 BTRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15473860 10882123
CTNNB1 CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20571031 12200448
ANAPC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8638126 9556553
DVL3 CSNK1D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CSNK1D APC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11818547
YWHAZ HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSP90AB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21730179 1105160108
AHSA1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16696853 20618441
AR YWHAH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19996220 8009645
AR CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20337887 20610535
AR F2R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 15629896
EZH2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 23239736
AR F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15629896
STK25 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK26 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
DLG1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ANAPC2 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC7 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
ANAPC2 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
ANAPC2 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
SUGT1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PIH1D1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAH MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HAX1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAZ MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PLOD1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CPVL MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IQGAP2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STK25 STK26 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
XPO1 EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
PRMT5 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
LMNA YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
BMPR1A BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10712517
ID1 BMP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20970407 21996749
BMP8B BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10504300
XPO1 MTA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
HAX1 XPO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23164465 8401898
XPO1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ GCN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
WDR77 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
WWC2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ WWC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
APC2 CTNNB1 â—¼   RELOCALIZATION ✅ - 0.8 0.8 Signor 10980707
APC BTRC â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HSP90AA1 MAP3K5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HSP90AB1 MAP3K5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
KIF23 YWHAZ â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
YWHAG DYRK1A â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
DYRK1A YWHAG â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 36950384
LATS2 SAV1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
LATS1 YAP1 â—¼   PHOSPHORYLATION ✅ - 0.81 0.81 Signor 22658639
CDH1 SRC â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
DVL1 DVL2 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
DVL1 APC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20224554 11425858
STK4 CDC37 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24366813 23455922
MYC PRKDC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
YAP1 CPVL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26933062 24366813
YAP1 GSK3B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24976009 29789528
AXIN1 AXIN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22682247 20128690
AXIN1 USP9X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22682247 17510365
BIRC3 USP9X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23524849 30948266
YWHAG MAP3K2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5217174 15324660
SAV1 AMOT â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30266805 24255178
STK4 XPO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26673895 23386615
TAZ BMP8B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
HRAS RASSF1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
USP9X YAP1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HSP90AA1 SRC â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
STK3 MOB1B â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 21808241
ABL1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
CDC37 FKBP5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 24981860
CCND3 CDK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16782892 33854235 26496610 9716181 33961781 26186194 23455922
PPP5C HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27880917
ACTB MDM2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24583282 24798327 17373842
SNAI1 MDM2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20385133 22128911 34040386
MYC XPO1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17314511 26673895 32140074 29467282
MYC LMNA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
STK4 RASSF1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
USP9X YAP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 26598551 29449692
DLG4 FZD7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12067714
TAZ BMP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
AXIN1 DVL3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22682247 12805222 20128690
RNF43 DVL2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32103169 25825523 25891077 32965059
WWTR1 AMOT â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20972459 33961781 26186194
AURKA LIMD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
YWHAG FRMD6 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217174 15324660
MOB1B MOB1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 24366813 33961781
TAZ LATS1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24107629 33141042 22078877
LATS1 LIMD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 20303269 24255178 25127217
BMPR2 BMP6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11401330 10504300
BTRC GSK3B â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
AXIN2 CTNNB1 â—¼   DOWN_REGULATES ✅ - 0.83 0.83 Signor 11940574
AXIN1 DVL3 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
HDAC2 SNAI1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
IKBKB SRC â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CTNNB1 SIAH1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
LATS1 STK4 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
AJUBA SNAI1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25314079 18347060
FKBP5 AURKB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25036637
MYC ACTB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11839798 29467282
YWHAZ YAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5217040 15161933
MTA2 HDAC2 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6613464 18451879
HDAC2 FOXP3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19276356 25609649
AURKB SUGT1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 32707033
AR SRC â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
LATS2 CPVL â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 24255178
LATS2 AMOT â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24225952 24101513 24106267 24255178 30266805
AR CCND1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
MOB1B STK3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
GSK3B CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 16293724
AXIN2 APC â—¼   PHYSICAL_INTERACTION ✅ + 0.84 0.84 Signor 10911903
LATS1 LIMD1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
AXIN1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 7025676 19131971
GSK3B CDC37 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23455922 29568061 33961781
LATS2 SNAI1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24157836 21952048
LATS2 USP9X â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 29183995 28720576 24255178
LATS2 LIMD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 20303269 24255178
LATS2 LATS1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 24255178 34079125 32707033 21233212
LATS1 STK4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24012335 15688006 33945069
FKBP5 HSP90AB1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
TP53 XPO1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
LZTS2 APC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 29395067
DVL2 APC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20224554 26496610
CDK2 TP53 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24173284
YAP1 YWHAG â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5217174 15324660
YAP1 AXIN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24976009 29789528
WWTR1 LATS1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20412773 27847303 29787761 26116754 22078877 21555462
AURKA LATS2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21822051 15147269 28628118 28205554
GSK3B TP53 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CCND1 XPO1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21654808 12529437
CCND2 CDK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9840943 28514442 33854235 33961781 26186194 23455922 9178893
MYC MMS19 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 17314511 29467282
MYC HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 22286234 30415952
PPP5C HSP90AB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 27880917
SUZ12 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24457600 26344197 22439931
EZH2 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10581039 24981860 21685935 26344197
HDAC2 SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 24981860 26344197 20075857
TEAD3 WWTR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 16189514 33961781 26186194
SIAH1 SIAH2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 16899216
SIAH2 LATS2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27030211 25438054
YWHAG KIF23 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 5217174 15324660
SAV1 HAX1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22570112 21567072
CHEK2 TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
STK3 MOB1A â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 23431053
STK3 STK4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SIAH1 SIAH2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
LATS2 MOB1B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDKN1A MDM2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AR STUB1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
APC CTNNA1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HDAC1 SNAI1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BTRC SNAI1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
GSK3B SNAI1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
AMOTL2 YAP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BTRC FBXW11 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CDC37 IKBKB â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CHEK1 TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
AURKA TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BTRC WWTR1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
AXIN1 BTRC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
APC DLG1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 30126976 23185543
CDC37 AURKB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25036637 33961781 26186194 31586073 32707033 29568061
CDKN1A LZTS2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
EZH2 SNAI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21685935 24903147 18519590
GSK3B SNAI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 15448698 19411070 28892081 15647282 31311807 20389281
SNAI1 HDAC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21685935 25314079 20534591 14673164 34026424
YAP1 LATS1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 25283809
YAP1 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 22234184 8383887
LATS2 YAP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18640976 21041410 25670202 34404733 30865227 33368671 18413746 18565851 26578655 28205554 28754671 25751139 19797269 30472188 29183995 28628118 21832154 25796446 22863277 26598551 21041411 30266805 19919647
AXIN2 GSK3B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12183362 10966653 33961781 23602568 32707033 23455922 29568061 30824926
BMPR2 BMP7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7644468 7791754
AXIN1 SIAH1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28546513 26871637
YWHAE YWHAG â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
YWHAZ KIF23 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8397056 22580824
YWHAE YWHAH â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
LATS2 MOB1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23886938 29183995 19739119 20624913 33961781 24255178 31941533 26898830
LATS2 MOB1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 19739119 33961781 24255178 32707033 19919647
LATS1 MOB1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16061636 16674920 33141042 19739119 20624913 24255178 31941533
MOB1B LATS1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 16674920 19739119 33961781 24255178 34079125 24366813 18328708
AMOT LATS1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 30266805 32292505 24101513 24255178 34079125 24366813
STK4 MOB1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22863277 24255178
GDF5 BMPR2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19229295 9525338
MAP3K5 YWHAZ â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BMP4 BMPR2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PRKDC TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AMOT YAP1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
BMP2 BMPR1B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
BTRC YAP1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AR KLK3 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CDH1 CTNNA1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
BTRC CTNNB1 â—¼   UBIQUITINATION ✅ - 0.88 0.88 Signor 10228155
CTNNA2 CTNNB1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AJUBA LATS2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20303269 33961781 16413547
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MYC GSK3B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16247449 11877389 14563837 20713710 19131971 21150319 31638140 8247524 29467282 33541412
SNAI1 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21685935 26794444 25314079 20562920 23011797 14673164 34026424
CTNNB1 YAP1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
AMOT YAP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 30266805 23564455 24976009 24225952 25751139 31501420 32292505 29891922 30472188 24106267 24255178 24101513 32755583 24366813 19615732 22385262
YAP1 TEAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27684187 25751139 25796446 26933062 35140242 24255178 24366813 11358867
TGFBR2 TGFB1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8044119 21054789
DVL1 DVL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24643799 28514442 20224554 33961781 26186194 31340145
DVL2 DVL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24643799 31340145 33961781 28514442
KIF23 YWHAG â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
SAV1 LATS2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25670202 34404733 25692647 24255178 30266805
STK3 MOB1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18362890 31941533 24255178 23972470
STK3 MOB1B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24255178 32296183 19919647
LATS1 ZYX â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10831611 16713569
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
BMPR2 BMP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28126904 12045205 7673243 7644468 8702914
STK4 SAV1 â—¼   UP_REGULATES ✅ + 0.89 0.89 Signor 16930133
CTNNB1 FBXW11 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
BMPR1A GDF5 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
EZH2 HDAC2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
LATS1 WWTR1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
SRC ABL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11494128 17474147 12522270 11781820 17318191
ABL1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16702947 25624478 12110584
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
ABL1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26603102 25219501
AXIN1 APC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16199882 22682247 10228155 29045831 18786926 20128690 19131971 26496610 10811618 9734785 29713058 23277359 17510365
SIAH1 APC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11389840 25241761 16713569
AXIN2 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10966653 10911903 9554852
CCND1 CDK2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
GLI2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14691458 12533516
CDC37 SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 33961781 31980649 11085988
HRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
HSP90AA1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
HSP90AB1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
ACTB CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SDF4 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CSNK1E WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24715453
HRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
HSP90AA1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14614132 15894266 15218035
AR MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
HDAC1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15640443 33985974 12426395 30818224
GSK3B MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055726 18505846
PRKDC MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17570479 22444248 10721693
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
MYC ACTG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PRKDC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19149881 24299953
MYC WNT10B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC BMP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC LMNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
AXIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19131971 20399964
SNAI1 GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17587812 23689589 16357176
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
TP53 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15383401 20332115 21478913
MTA2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11099047
YAP1 BTRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YAP1 LATS1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18640976 27325643 32292505 27684187 27886176 21383157 18413746 33141042 26933062 24366813 31619268 28754671 30461308 27847303 25751139 29891922 17889669 30472188 28416659 25283809 24107629 22641346 18158288 25796446 22863277 20841485 24255178 21041411 34079125 30266805
YAP1 LATS2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17974916 21832154 21205866
YAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23607968 22234184 23245941
FZD7 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14636582 22179044 19388021
FOXP3 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27861999 20554955 19797626
FNTB HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15451670 24294527 2217184
AXIN1 DVL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10829020 29659741 23892894 21245303
AXIN1 GSK3B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 17601533 21988832 10228155 24976009 30181396 20128690 12511557 17318191 16293724 23455922 28546513 17318175 19303846 18632848 19131971 16890161 26496610 23892894 23602568 22613765 18593713 29568061 21242974 22682247 19759537 11738041 22270359 24451375 9734785 32707033 21502811 17510365 10481074 16199882 26912724 23959799 29045831 22509369 29789528 19202075 12584189
APC2 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9601641 10980707
ANAPC2 DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19805045
DVL1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10428961 16914735 20837657
MTA2 HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 31980649 19703393 22939629 30737378 20714342 26949739 10444591 21258344 24981860 12493763 19686092 11102443 12920132 18451879 11297506 26344197
AURKB BIRC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11516652 31315909 19951914 20430883 21554500 23945651 19357306 29568061 21051298 32738097 18477699 17681274 17099693 19995937 16291752 27332895 12419797 31586073 24571573
AR CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18794357 20610535
RNF43 FZD4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23847203 20495530 22575959
SRC PPP2R1A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
CSNK1D WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24715453
GLI2 PRKACA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17283082 19056373 16611981
CIT DLG4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9870943 9870942 16202622
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SAV1 STK3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 32296183 21988832 15688006 20920251 20562859 16930133 33961781 24255178 26186194 24981860 17379520 23455922 24366813
MOB1A STK4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23386615 24255178 21516123 31941533
STK4 STK3 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
STK3 STK4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 28628118 20562859 20920251 24981860 23386615 24255178 28205554 24366813 23455922 26344197
GSK3B FZD5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AR GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20127713 20610535 18687691
CSNK1D GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21316585 23331499 11818547
GSK3B AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15361837 15178691 14985354
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CTNNB1 BMP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10601040 12782598 15907834
DVL3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10644691 10806215
AR HIGD1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11867260 20610535
EZH2 SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21135039 21884980 27338022 18931660 28068325 23079660 24469040 19026780 21190999 26496610 26748827 24320048 33849069 35016035 27634302 29669287 18285464 20543829 18453536 31130994 21123648 20123894 24183680 27728805 25470042 12435631 22939629 16224021 23624935 24457600 26344197 20075857 15882624 23684459 31786184 31281901 23238014 26130719 19026781 27705803 22439931 27303043 31631027 24981860 33961781 19734898 31948940 18483221 21378168
BMPR2 BMP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10880444 10712517 25938661 7791754
CTCF SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18662993 21536749 33196849
WNT10B FZD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 11092808 12055200
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BMPR1B GDF5 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ACTB CDC37 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CCND2 CDK2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
HDAC2 SUZ12 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CCND3 CDK2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
NUP214 XPO1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
APC GSK3B â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CCND2 CDKN1A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
STK4 MOB1A â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 21808241
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CTNNA3 CTNNB1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
TEAD3 YAP1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ACTG1 CDC37 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
HSP90AB1 PPP5C â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
LATS2 STK4 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 30865227 24255178 26578655 30266805 26898830
DLG1 DLG3 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 33961781 12351654 26496610
BMP4 BMPR1A â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
MDM2 USP7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
YAP1 YWHAZ â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
AXIN2 GSK3B â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
AXIN1 SIAH1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
LATS2 STK4 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
DLG2 DLG4 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 9182804 21653829
CTNNB1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218183 16376880
CCND3 CDKN1A â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
LATS2 STK3 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
AURKB BIRC5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
RASSF1 STK4 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
RASSF1 STK3 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CTNNB1 AXIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219694 17318191
MTA2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6613464 18451879
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
STK4 SAV1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
LATS2 MOB1A â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
MOB1A STK4 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
APC2 CTNNB1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CHEK1 CHEK2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
CDKN1A CCND2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 16765349 5218735
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
DVL1 DVL3 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32296183 10330181
DLG4 DLG3 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10026200 28973854
STK3 SAV1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
FNTB FNTA â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
LATS1 STK3 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
CDK2 CDKN1A â—¼   PHOSPHORYLATION ✅ - 0.95 0.95 Signor 15964852
HDAC1 MTA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
CTNNB1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 36950384
CCND1 CDK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9840943 28514442 8647086 33854235 8479754 26496610 33854239 33961781 23455922 21654808 9178893
EZH2 HDAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 21685935 15520282 10581039 24771265 31130994 22439931 26344197
AHSA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HSP90AA1 PPP5C â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MOB1A STK3 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
HSP90AB1 SUGT1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
APC GSK3B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11166179 29045831 21118991 8638126 11251183 23602568 29568061
AHSA1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
USP7 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6799761 18566590
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
AXIN2 CTNNB1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
HDAC1 MTA2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 31980649 19703393 10444591 21258344 12374985 17956988 11102443 27068747 26496610 20127688 11171972 11297506 20585571 21670149 11602581 22939629 18451879 23752268 9790534 26949739 16645043 22863883 28179136 27173435 24981860 33961781 19686092 12920132 26344197
SAV1 STK4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 30266805 20562859 20920251 25692647 17517604 16930133 23386615 24255178 26186194 27173435 33961781 24366813 24981860 23455922
CTNNB1 GSK3B â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
BMPR1A BMP2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 19804412 7261592
ANAPC5 ANAPC7 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
SAV1 STK4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
LATS1 MOB1A â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDKN1A CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16765349 5218735
LATS1 MOB1B â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
HDAC2 MTA2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
SAV1 STK3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
GSK3B YWHAZ â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ANAPC5 CDC23 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ANAPC1 ANAPC7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
LATS1 YAP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ANAPC7 CDC23 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CCND1 CDKN1A â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
PRMT5 WDR77 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
AXIN1 DVL2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
BMP2 BMPR1A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
HSP90AA1 SUGT1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MOB4 PPP2R1A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1A STK25 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MOB4 STK25 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
LATS2 YAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CTNNA1 CTNNB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AXIN1 CTNNB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ANAPC1 CDC23 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
FNTA FNTB â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CDK2 CDKN1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
AXIN1 GSK3B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BTRC CTNNB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC1 ANAPC5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 ANAPC5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC1 ANAPC2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 ANAPC7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ABL1 YAP1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10837221 11804596 11971963 12628935 12709442 15459660 18835194 19788416 21051857 21199784 21435002 9168117
SRC ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 19901323 10964922 16497976 20841568 16787943 17570479 17318191 11847100 10500097 12522270 18691976 11494128 11781820 16076903 20168609 12748290 16464493 12445832 19369195 17474147
ABL1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15686624 9109492 9295282 9312071
ABL1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26721416 27618557 24868554 21715626 30903103 22590567
ABL1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 23331499 12110584 20651945 29065514 22352870 16702947 25973395 27626309 21081495 27956626 20841568 14757045 19738896 15212693 28690977
ABL1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 25361080 19788416 21199784 29449692 18955976 21051857 18280240 21435002 18701449 27807512 20841568 21214929 21945154 29179447 15459660
ABL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 16099633 25164010 17618275 24465953 20841568 17318191 20840866
ABL1 AHSA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 26235616 27515256 29127155 26693507
ABL1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 27618557 22590567
APC AXIN1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10421629 10581160 11487578 11955436 11967263 12051714 12554650 15001769 15327768 16039586 16288291 16940750 17143292 17318175 17936032 19619488 19751508 20006983 20705860 22270359 23343194 24023259 25730849 7542250 8638126 8666229
APC CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
APC AXIN1 â—¼   PROTEIN_INTERACTION 26.0 1.0 ACSN 10421629 10581160 11487578 11955436 11967263 12051714 12554650 15001769 15327768 16039586 16288291 16940750 17143292 17318175 17936032 19619488 19751508 20006983 20705860 22270359 23343194 24023259 25730849 7542250 8638126 8666229
MYC APC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22911891 12695333
CSNK1E APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17145710 25241761 11425858 17570479 24722208 15327768 11487578 17218255
PRKACA APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11050185 11166179 15649893 11689703
GSK3B APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 16944320 11166179 16799642 11967263 14663202 8524413 12554650 8638126 17910481 15327768 10581160 11487578 17318175 15465828 10228155 15020233 10421629 10698523 9832503
CSNK1D APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17910481 15327769 15747065 11487578
AXIN1 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16199882 20128690 19131971 11297546 9554852 22682247 10228155 26496610 23277359 10811618 9734785
APC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 10545404 11166179 8259519 7890674 22083140 27902311 8638126 16212417 16798748 19061640 9286858 15327769 9482734 11533658 22056988 19576224 15327768 17318191 26496610 12628243 15355978 9065403 11712088 25241761 26910375 22682247 9065401 12000790 11707392 20219694 9707618 23840886 15525529 11251183 8628279 19631635 11972058 21664290
MYC BBC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12695333 12384701 19815507 20145032 21835778
TP53 BBC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 23916609 14665630 18397889 17390010 22763818 11463391 15988033 16462759 17280505 22948151 16151013 20190809 23678107 17989286 17360476 11756653 20331637 21835778 15790310 17440969 20478995 17047080 12384701 18657356 18755897 15489892 18579560 11463392 11572983 15007388 17610896
TP53 BBC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12574499 11463391 11463392 14634023 14684737
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
ID2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19587095 21194482 22835384 12527902 17559421
TP53 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 24189068 8702807 10669755 22270849 12808109 17942917 19086036 20731879 16061648 20554748 24460719 11798189 10082575 15205322 18769160 19800042
CTNNB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16628468 10318916 12095419 15111320 15735151 18679417 17360646 12782598 10201372 14557550 19778454 20300972 19662654 12589056 11943708 10915780 17693601 15592430 17109766
GSK3B CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 87.0 1.0 Omnipath 26907733 16944320 27546592 11967263 14663202 8524413 16504004 29969496 19767775 21347341 25142862 11311237 30736789 14597415 25591548 19645770 10385618 20548028 10766840 10929713 23565238 16039586 17570479 18818515 18167338 12615961 12413951 17046823 19071090 18598945 15465828 19374252 26121043 26432751 18319725 12969793 23733133 22922870 24134204 10486203 12459251 15020233 18769147 10910956 11152665 21317297 20537194 22099186 18328826 11124803 17070615 19757160 22470469 23552696 16732330 27695879 29554905 16103118 15075324 14536078 9832503 28090171
DYRK1A CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 16504004 33521925 19412162 27285583 19767775 20951943 21241249 20548028 10766840 17046823 26008897 15735756 16601140 16153639 11751903 33854232 18650423 24431113 16732330 16103118 33854239 17081987 24119401
HDAC2 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799 15713663
CDKN1A CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 26203195 23443559 17145710 25416956 7478582 9837900 21988832 21516116 7777546 15232106 16082198 27107012 15695403 8657154 8242751 23007395 9106657 12383116 17556661 8756624 8662825 31515488
CTNNB1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 11836555 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 17208333 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
PPP5C CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21360678 18922470
MYC CDK2 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
MYC CDK2 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
CDK2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8386367 27653698 17081983 19966300 18669648 29896817 17570479 20713526 17558397 15103331 22348395 20445224
CDK2 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20935635 25800736 29576612 23241245 32368395 29556394 17570479 27863310 26279746
CDK2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 94.0 1.0 Omnipath 23443559 23455922 10878006 20100570 23602568 15964852 20839231 25416956 23737759 9840943 18850315 11302688 20519948 24358021 19440234 15557281 9472014 9658399 16962592 9736735 12949733 8641969 10022118 15890360 12839982 16765349 17418410 15647383 10874474 15232106 17570479 17698606 12361598 26496610 9632134 24419005 12417722 16189514 26186194 20587660 25241761 8622677 9660939 25483090 12800980 20102411 10918595 12058028 12144826 8242751 9464540 9858587 29899857 23007395 11477082 9218599 12383116 25463440 12730199 8756624 9284049 9380407 9546435 24218572 16964243 15212693 13678583
CDK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 24173284 9315650 19413330 19664995 16083285 1088347 16552184 10884347 17570479 10747897 25241761 7624134 11687964 17287340 92065884 12064478 19556892 14640983 10348343 14702041
CDK2 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21765472 21965652 21907702 18983824 24242917
CDK2 ID2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 28122577 9029153 14733935 26110849
CDK2 DLG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19066288
ID2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17639499 16557594 21900881 16428453 11706002
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
AR CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16281084 10076995 11606392 10606230 20610535 10809237
EZH2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21572997 21546904 24074410 21629038 22956625
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
ID1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20388787 17639499 10728702 20191379 23342268 20484992 19217708 9315646 22564737 18092003
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
MDM2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17373842 25241761 20086099 14633995 14761977 20308078
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
MAP3K5 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17325029 12820963
GSK3B CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 22154077 28916781 12058028 11779850 17570479 20519948 15212693 17283049 19440234
CDKN1A CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23443559 26186194 25241761 27107012 8756624 15169570 25416956 16765349 31515488 16189514 32296183
CDKN1A CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 21988832 23443559 26186194 25241761 27107012 8756624 25416956 16328436 31515488 16189514 15232106 32296183 23880157 26496610 9716181
TP53 CHEK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21546904 11158294 20190799 19435816 18632613 15016801 19395378 11152453 18753293
CHEK2 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26516160 24804719 26437226 29555944
CHEK1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23321637 22024163 17276342
CHEK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 20950777 18778462 25545885 18677104 20860841 15798197 19793801 22891162 16511572 23852422 16713569 15865930 11551930 19923893 15467443 11709713 21748595 17116885 15659650 17582221 26384650 10673501 17384638 23966620 23892398 17118344 9765199 15140942 19788416 10801407 18319725 12781359 12897801 25823026 15459660 23296650 15024084 17296725 17102137 11896572 17339337 19933256 20526329 28140789
CHEK2 TP53 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10710310 10673501 10570149 10673500
TP53 CHEK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15326376 19435816 10531348 19395378 15044452
PRKDC CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 77.0 1.0 Omnipath 31959038 12607004 22669845 18948271 16794575 24492479 15829965 23684611 12805407 20406977 26929199 21482692 27818175 20660628 33870196 11668173 21731742 33879618 15618221 11901158 24421316 21099343 12386164 15096610 24415760 12447382 12855706 15213307 16150728 20599567 16024600 17570479 12447371 28750002 34244606 33901880 15367709 26505995 16940182 33747205 11025670 12024051 24844881 15668230 10973490 20713355 33961649 19151762 16936775 16798742 12607003 30001349 18644861 25361978 20305300 11390408 20501833 15361851 16982735 23380594 15674326 17237275 20160490 20498628 33851958 15282313 25550082 31609975 15975956 11085506 12493754
CHEK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 18778462 25545885 16893723 15254178 18833288 23892398 12052256 18319725 25372714 15459660 20514219 25174607 28140789 17339337 22420423 18566216 20950777 20651945 15810020 15700044 22891162 17157788 11551930 18725978 10724175 15467443 23351141 20096447 11063934 11709713 15659650 12242661 10656682 15140942 20041275 11728459 18614044 12781359 22649771 18812180 11173129 10570149 15279785 20081365 20860841 11875057 22778557 19923893 24553354 22797063 26384650 23316480 15489221 19788416 10801407 21187893 9843217 9733514 10710310 24358900 21526939 23843721 29805302 9733515 25404613 12548019 21625617 10673501 11447225 17118344 26610585 19544417 28038466 12810724 25823026 15024084 17464182 15862297 19933256 20526329 12111733 20183804 23144912
CHEK2 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15862297 10710310
DVL1 CSNK1E â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12556519 21285348 11818547 11425858 10535959 16965538 10517632
DVL2 CSNK1E â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12556519 21285348 11818547 11425858 10535959 16965538 10517632
CSNK1E DVL3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 12556519 21285348 11818547 11425858 10535959 16965538 10517632
CSNK1E CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 9312064 7641885 15265686 19718039 21602792 14966280 210606194 8655584 19705439 11818547 19029934 20093472 17430994 21606194 17884187 11955436 9482734 14747478 17570479 12176352 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 12000790 12114015 16547521 10488109 19020754 20940130 12417018 21640127 21087212 17127310 21796133 10023673
CSNK1E TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10606744 11709713 10951572 10734067 16713569 11551930 10747897 10673501 11883897
CSNK1E AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 10535959 22682247 11884395 26496610 11487578 12000790
CSNK1E DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 32888647 31515488 22609948 16189514 16713569 10517632
CSNK1E YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24715453 23431053
CSNK1E DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 11425858 20006983 14966280 20215527 16965538 21285348 11487578 11818547
CSNK1E GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 21233202 7641885 16611981 21536646 19797085 18455992 16371461
DNAJC7 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19875381 20661446 12853476 15189447
DYRK1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20696760 24901999
AR FKBP5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15821585 19433513 20048054 21809344 11867260 16210365 20610535 17142810
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
AHSA1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 25036637 16696853 17145710 19875381 12604615 24462205 26693507 26804907 22315411 12504007 20226818 20159553 22504172
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
HSP90AA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1525041 19805354 20048054 15861399 17974989 26342197 17353003 26196320 16713569 27903893 1540595 21157430 19706771
HSP90AA1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1310678 16844778 16189514 18266962
HSP90AA1 PPP5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10400612 16531226 21360678 15577939 15383005
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
USP7 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 17936559 26460617 15916963 24462112 22056774 18566590 20816748 16402859 20713061 16943424 17380154 29236775 16082221 26238070 34799561 16845383 16474402 28406480 27452404 28196907
CSNK1D MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 26294215 11850850 12167711 16055726 15610030 15688025 15703839 20708156 28049764 33618712 15024078 19630168 26636645 19008219 27617579
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MDM2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17974989 26411689 27835608 26973243 15640443 12145204
MYC AXIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC AXIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC TGFB1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
MYC CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7739536 10931841 11673469 10657901 12177005 14519204 9111322 9811896 10567564 17706770 24771621 11983916
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
MYC CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9632747 19176757 23364919 10523846
MYC CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7526316 11511535 10508165 9339900 15988028 20857481 11060032 14519204 14660677 10956386 21790895 11264343
MYC ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12447693 12695333 12824180 18437010 18483244 12545167
MYC AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20890087 20519624 14744757 20682043
MYC BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17170079 19287963 20508797 19602047
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
GSK3B MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 73.0 1.0 Omnipath 17081983 18463697 21646472 30037819 26751215 25647305 2663470 20080742 19797085 30003124 16855632 12040186 18679417 11018017 23331499 29229669 16611981 21071413 24265759 20068231 10671551 16039586 17570479 16023596 29258530 12615961 18669648 21113395 22461507 19131971 8247524 16247449 20604938 19575820 15150404 22481935 23668310 19651622 17444818 23964270 20537194 22893788 27684546 24662831 25333250 20399964 11877389 14563837 18408012 17052453 18455992 15212693 16371461 11274345
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
DVL3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
MYC CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8425218 15121849 11602341 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
MYC GCN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20936779 17353931 17314511 17093053
PPP5C MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17456047 11689443
PPP5C PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14734805
PRKDC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 15355354 19398950 15254178 9372954 11483158 7862459 16713569 11875057 11551930 11883897 12548019 25168287 8502477 11709713 10446957 28145533 22726545 24886358 16552184 12242661 17570479 10196661 10747897 9885574 10673501 12091386 22355272 9765199 15489221 9561848 10801407 22504299 22444248 15177184 11042698 10358069 10470151 10606744 9744860 16397295 12959929 12064478 27130668 10951572 12111733 25937999 15381073 28102346 9363941 19918261
TP53 RASSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23779024 23038753 21364923
AURKA RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22438769 17563743 19276349
AURKB RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19887622 19276349
HRAS RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16810318 17145710 18596699 32814053 10998413
RASSF1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17379520 24366813 26186194 14729613 22195963 24255178 20920251 21808241 21199877 19962312 20086174 32296183 17598981 29063833 18347058 17889669 23455922
RASSF1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 20562859 17145710 24366813 26186194 14729613 26578655 24255178 20920251 22683405 15109305 23386615 17598981 21808241 23455922
SNAI1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 ID1 â—¼   UP_REGULATES ✅ + 66.0 1.0 ACSN 10048576 11283614 11708773 12490555 12545156 12668723 14623871 14673164 15111329 15151915 15155580 15181457 15448698 15459715 16001073 16079281 16232121 16510505 16556862 16617148 16716598 16831886 17018611 17055429 17093497 17403902 17490644 17537911 17550342 17563753 17615296 17671186 18172008 18297062 18832382 19208835 19412634 19564415 19597490 19935649 20027199 20702634 20706219 20713526 20731704 21041997 21051859 21159887 21199805 21317430 21577210 21685935 21883379 2191300 22006115 22286765 22406545 22439866 22514743 22796940 22945800 23140366 23869868 8844971 9157999 9618481
SNAI1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 71.0 1.0 Omnipath 16502042 16424022 18347060 19874710 23054398 11912130 12668723 21081648 24168186 20455091 16617148 19635798 24424621 15300012 22775504 12508111 25025961 23637992 20576520 24228088 18701475 20562920 22562246 23424071 21685935 15026811 24504364 18801366 19055748 18321996 17060462 23295740 22128911 23752226 24293287 16273209 19893985 18385519 23671646 17724139 24305977 20801642 10655587 15492833 19789323 21846773 19784072 17082242 17671186 22911555 14673164 16804902 17490644 23658826 18519590 12579345 22158034 17655524 24095903 18565826 20053763 15311212 15448698 19179606 12161443 22614005 18773488 21796367 24448241 16322400
LATS2 SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 34335956 27840647 26831822 21952048 24168186
GSK3B SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 16944320 11967263 14663202 8524413 23449453 15459715 22745173 16189514 15121840 19131971 15465828 29147673 20305697 19366350 15020233 16511445 19923321 15448698 19004823 9832503 15647282
SNAI1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 15169839 17615296 22796940 20818389 21685935 20519943 12508111 11309385 17018611 22514743 19597490 14673164
TP53 PPP1R13B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11684014 18676979 14729977 18275817
TP53 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 19363521 19470765 19067706 17124180 11714700 16432013 18698017 21443519 12235242 20236666 22266808 16595680 15361831 23838170 17916908 15087401 15377848 19018856 19439469 22503977 17699779 11965534 15657147 18022393 18027854
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
TP53 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17530187 19861536
TP53 HRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21552926 9662334 11127813 21552928
TP53 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12732139 10618379 22264233 23706820 14514686 8183578 14761612 16138117 18593586 23063463 8119773
TP53 KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15540784 11791186 11504717
TP53 AFP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11572852 14522900 11798803 11891535 18212064 15743813 16203738 18573881 15657445 9891062
TP53 SIAH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20181957 20421190 14985507 11852084
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
CSNK1D TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 10606744 16870621 17101137 9349507 25241761 11709713 10930428 10951572 17570479 19345189 11551930 10747897 10734067 10673501 11883897 16713569 18246126
GSK3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23840442 12064478 11709713 9372954 11483158 16552184 17570479 14744935 16713569 21929745 12048243 21900206
AURKA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 24173284 22864622 25217103 24089029 16713569 19413330 25848977 17999753 23565200 25333414 23201157 16552184 10884347 1956339 26186194 29455673 15469940 15749021 18974145 21502403 17287340 28043820 22396649 92065884 12198151 27933271 22852086 12064478 30266789 25398437 17259342 22350019 25634113 14702041
AURKB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 20959462 27933271 20847049 15469940 32873634 22611192 27496712
TP53 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19211844 11965534 11714700
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
TP53 SIAH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12077306 12438652 14985507 15326481
YAP1 WWTR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338
YAP1 WWTR1 â—¼   PROTEIN_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338
LATS2 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 36.0 1.0 Omnipath 22863277 20048001 18413746 24525530 15302935 19797269 17974916 18640976 18369314 29179447 18669648 25670202 26578655 29680477 18565851 21233212 21041410 18158288 19919647 18220336 21832154 22658639 21041411 24976283 26598551
BTRC YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20048001 23431053 24976009 21900206
AMOT YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 32755583 21205866 26269582 21808241
CSNK1D YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24715453 23431053
LATS1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 22863277 24366813 35044719 20048001 18413746 17889669 15302935 21383157 23752589 17974916 18640976 22641346 23027127 20841485 18369314 29179447 18669648 24255178 18565851 21909427 21170084 25283809 29487715 18158288 29496737 18220336 22658639 35210364 27325643 19141641 21041411 25180175 27322327 27847303
PRKACA CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 37.0 1.0 Omnipath 19651622 17081983 1359877 18767875 17322306 18691976 4092695 19664994 20068231 18707149 23429703 11986331 17206380 14991569 19664995 18669648 33771897
DVL2 FZD7 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23821037 15936275 10698942 9716412 17130287 9674432 17627283 11358862 11101902 12015986 14636582
CTNNB1 AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24447505 15473860 11809809 22615875 11809808 12711682 11940574
HDAC1 AXIN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
CTNNB1 AXIN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10966653 19751508 7542250 8666229 17143292 11955436 11967263 23343194 22270359 9554852 22699938 16039586 16940750 9566905 19619488 15766563 12051714
AXIN2 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15611123 10966653 10911903 888800000547 9554852 22745173 9566905 22322943
BMP7 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15621726 106311828605097 8605097 10631182
BMP7 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18342887 16446785 7791754 7644468
BMP7 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16189514 7791754 12297674 8605097
ACTB IQGAP2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9368021 17244649 8756646 21730051 9199170
CCN2 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12736251
ACTG1 IQGAP2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9368021 17244649 8756646 21730051 9199170
TGFB1 ID2 â—¼   DOWN_REGULATES ✅ - 27.0 1.0 ACSN 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 7594497 9157999 9335507
CTNNB1 ID2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15252039 19751508 7542250 17615296 8666229 11708773 11967263 11955436 22270359 16940750 12051714 15181457
TGFB1 TGFBR2 â—¼   PHYSICAL_INTERACTION 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFBR2 PARD6A â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 11133108 14557817 15265520 15548370 15761148 15761153 16474430 17934056 19010789 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22315516 22703233 22949611 24132110 24336330 7594497
TGFB1 TGFBR2 â—¼   SHARES_COMPLEX 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFBR2 PARD6A â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 11133108 14557817 15265520 15548370 15761148 15761153 16474430 17934056 19010789 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22315516 22703233 22949611 24132110 24336330 7594497
TGFB1 TGFBR2 â—¼   ENZYMATIC_REACTION ✅ 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFBR2 PARD6A â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11133108 14557817 15265520 15548370 15761148 15761153 16474430 17934056 19010789 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22315516 22703233 22949611 24132110 24336330 7594497
TGFB1 TGFBR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 122.0 1.0 Omnipath 1310899 22874531 8047140 11279127 22710166 7878020 16424049 17673906 24132110 18922473 22943793 12729750 16446785 20519943 7706250 15761153 7594497 15548370 15761148 15265520 19010789 26194464 7852346 12717440 17768418 19050695 11133108 14557817 11278410 19920116 22949611 22703233 23331499 23070005 20060931 17070508 21614932 1333888 10716993 16572188 20860622 11323414 21900405 12724770 8106553 23034983 26192618 2871107 12809600 11382746 21372296 20538542 16200688 11792802 26201938 24403530 15099563 11013220 17979848 21054789 23784029 15003992 20644162 8515656 7935686 11157754 20856203 18382895 15282297 18855897 9865696 21441952 10678166 16127449 21041659 10026191 22315516 12767520 17404308 19732719 20616810 21071413 17934056 12738796 18423981 21098712 19747910 9311995 15034927 11274345 12154066 18758450 24336330 21278795 26966341 9261125 16474430 15653932 18490733 8242742 19038247 19109155
TGFBR2 PARD6A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15761148 25756394 24231509 23249950 19114990
TGFB1 PARD6A â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 11133108 14557817 15265520 15548370 15761148 15761153 16474430 17934056 19010789 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22315516 22703233 22949611 24132110 24336330 7594497
TGFB1 PARD6A â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 11133108 14557817 15265520 15548370 15761148 15761153 16474430 17934056 19010789 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22315516 22703233 22949611 24132110 24336330 7594497
TGFB1 SRC â—¼   ENZYMATIC_REACTION ✅ 56.0 1.0 ACSN 10671552 11133108 11348595 11476890 11955436 11967263 12051714 12426320 14557817 15001769 15279786 15548370 16039586 16099633 16371504 16474430 16919435 17143292 17303408 17496910 17517963 17660363 17928543 17934056 17936032 18037882 18590585 19010789 19029934 19109155 19171760 19619488 19734908 19920116 20519943 20644162 20705860 21278795 21666923 21900405 22007144 22174153 22203675 22370635 22674073 22703233 23343194 24023259 25572304 25730849 26552706 27216177 7542250 7575488 7594497 8666229
TGFB1 PARD6A â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11133108 14557817 15265520 15548370 15761148 15761153 16474430 17934056 19010789 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22315516 22703233 22949611 24132110 24336330 7594497
SRC HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12695509 9626657 9020108 25157176 33413561
DVL1 AXIN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
AXIN1 FZD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
AXIN1 FZD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
AXIN1 WNT8B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
AXIN1 DVL1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 10428961 16288291 16940750 19751508 22270359 8666229
AXIN1 DVL1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 10428961 16288291 16940750 19751508 22270359 8666229
DVL2 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10329628 10829020 21245303 23892894 16713569 17529994
GSK3B AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 102.0 1.0 Omnipath 20128690 16944320 11738041 20043192 12511557 11967263 16890161 22613765 14663202 23602568 8524413 24451375 19303846 12554650 8638126 22509369 18593713 16199882 21988832 23331499 19759537 10428961 9482734 22270359 19202075 17570479 16293724 15327768 10581160 17318191 11487578 22773187 26496610 16568235 17318175 19131971 15465828 26912724 25241761 24976009 21242974 22682247 10228155 23579495 12584189 23959799 15020233 10421629 10488109 11278246 9501208 18632848 10481074 10535959 10318824 9554852 17601533 9832503 21502811 9734785 23455922
CSNK1D AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21316585 12000790
DVL1 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 12556519 11278246 10862053 10330403 10330181 10428961 9482734 10196136 11027605 18339531
AXIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 20128690 20531388 16890161 27902311 22509369 18593713 16199882 23331499 9482734 21071413 26496610 19244247 22773187 17318191 10196136 18988627 17208333 19131971 24976009 22682247 10228155 12805222 12000790 10488109 9501208 9601641 18632848 9554852 19166851 23959799 12421363 9734785 11940574
DVL1 FZD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL1 FZD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL1 WNT8B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL1 GSK3B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
CSNK1D DVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21316585 23331499 11818547
DVL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 25241761 10806215 20006983 15735151
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20580679 19182791 21685935 21184735 24424621 18794357
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
HDAC1 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20081843 21234400
HDAC2 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15169839 17615296 25241761 22796940 20818389 21685935 15388328 20519943 12508111 11309385 17018611 22514743 19597490 14673164
BIRC5 AURKB â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
BIRC5 AURKB â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB KIF23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15630414 30728176 16461284 25512391 19203582 15854913 20451386
AURKB BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17145710 23955284 21554500 16291752 18477699 12419797 27332895 19357306 14610074 20807437 17457057 29371939 17099693 11516652 24571573 17681274 21051298 19995937 16769825 20430883
CTNNB1 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19778454 17005722 19662654 11517919 16288908
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ID1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 23555842 16007183 17639499 17202424
EZH2 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18377425 22130667 21685935 21770894
EZH2 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 15169839 17615296 22796940 20818389 21685935 20519943 12508111 11309385 17018611 22514743 19597490 20574448 14673164
GSK3B CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16944320 11348595 11967263 14663202 8524413 20080742 19797085 12040186 16611981 10671551 16039586 12615961 15465828 17928543 24063632 10671552 15020233 19575820 17444818 20537194 17052453 9832503 18455992 16371461 11274345
CDH1 CTNNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17145710 7542250 19016843 25468996 9326449 16212417 11960376 11801604 8227214 10381631 16219695 9700170 24336504 22750944 9233779 11226248
CDH1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17496910 19029934 22370635 16099633 23343194 19734908 10744074 16039586 22203675 19171760 22007144 19619488 17143292
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
DVL2 FZD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL2 FZD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL2 GSK3B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
DVL2 WNT8B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
FZD4 DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12958364 27096005 23331499
CSNK1D DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21316585 22609948 29426949 31579410
WNT8B FZD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
DVL3 FZD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
GSK3B FZD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
FZD1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
AR SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19305643 10454563 18687691 17108144 17079466
PRKACA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19651622 17081983 20166139 2474754 18088087 15546918 19664994 11804588
SRC AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 28144231 15062576 20570899 25133482 21318111 11032808 25950519 21512132 17525795 12933816 20383201 24728074 24948875 24868554 25547388 19117998 21956655 17045208 15027889 24859991 15466214 26829214 21886458
SRC HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17855507
SRC IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 12645577 12707358 15456896
SRC DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24981431 16990796 14529711 18721130
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
LATS1 WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23026745 22078877 20412773 22658639 33086783 24550007 21808241 29787761 34022224 20594350
LATS2 WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22658639 18227151 21808241
WWTR1 TEAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 31515488 16189514 23431053
SKI GLI2 â—¼   DOWN_REGULATES ✅ - 16.0 1.0 ACSN 11001584 12435627 15087129 16054035 16169709 16396903 16406505 16413481 16880536 17000779 19032343 19114989 19809516 20107231 20562908 9216996
BTRC GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 17053147 15340381 16611981 18813803 16651270 12820959 19797085 15071497 15688063 16371461
GSK3B GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17444818 16611981 20537194 10671551 20080742 19797085 16039586 19575820 12040186 17052453 12615961 18455992 16371461 11274345
FBXW11 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17053147 15340381 16611981 18813803 16651270 12820959 19797085 15071497 15688063 16371461
PRKACA GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16611981 20027184 16885213 17419683 19056373 19996099
CSNK1D GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 21233202 7641885 16611981 21536646 19797085 18455992 16371461
PRKACA AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 23861900 16222244 16246726 33744274 29764989 26165940 11039908 17545617 27242098 26481147 28869606 26134678 33988677 26831064 33760847 16083426 17895985
AURKA LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 21118956 21788394 25482410 15147269 10673337 21822051
MAP3K3 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15218148 17145710 9819420 15572679 11429546 15214841 14743216 15371334 16267042 14636585 16737960 17197697 9346241
LATS2 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21118956 25086053
YWHAE YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAG YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAH YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
SAV1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 20562859 21988832 17379520 24366813 16930133 26186194 17145710 24255178 20920251 21084559 15688006 32296183 29063833 23455922
SAV1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20562859 17145710 24366813 16930133 26186194 24255178 20920251 21084559 23386615 25692647 17517604 23455922
STK4 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 26898830 26578655 24255178 23431053 21808241
STK3 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26898830 21832154 15688006 23431053 21808241
STK4 MOB1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24255178 23386615 23431053 21808241 18328708
STK3 MOB1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23972470 18362890 23431053 21808241 32513747 30038061
STK3 MOB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19878874 32296183 23431053 21808241 18328708 19919647
STK3 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22195963 29970086 19962312 15688006 30038061
STK4 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15688006
LATS1 ZYX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10831611 16713569
AR PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12933667 10075669 9886819 15691881
PRKACA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 33914026 16199882 22173096 21303971 33815677 22094462 17287208 26068882 26884171 33605402 21506126 24117889 12297048 21822311 16476742
PRKACA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 16543730 15845746 18691976 19836308 8524413 12054501 16039586 12147701 16522636 11035810 18669648
PRKACA YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 29109150 11956222 12861023 16376338 19451227
CTNNB1 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
GSK3B CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17486076 11152665 20537194 10385618 11124803 12969793 19757160 16732330 10486203 16039586 14536078 18167338 12459251 12615961
GSK3B CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 11152665 20537194 10385618 15252116 11124803 16331257 12969793 19757160 16732330 10486203 16039586 14536078 18167338 15326477 12459251 12615961 17092340 15212693
CTNNB1 CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
GSK3B DVL3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
GSK3B WNT8B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
GSK3B FZD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
GSK3B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 183.0 1.0 Omnipath 22415718 11967263 27158593 29455668 19303846 19797085 8638126 19293931 23056571 22662165 25352148 16611981 27068260 28337019 10671551 21743491 20688898 16293724 23721711 23552738 18687691 28977889 19622173 12051714 25241761 27683053 28549350 22699938 19565571 23076981 21562161 19575820 20219694 20537194 10330181 21986938 29183346 27773936 11251183 19711366 21035499 19675674 7542250 23151663 24451375 14663202 23804296 8524413 25639486 23770025 18070361 26892600 30143633 9233789 19667122 27507058 19061640 19223551 29387014 23331499 16199882 11533658 18644116 24501426 24913829 11835406 17318191 26014148 25366337 28183999 22640743 26910375 12000790 12114015 18387957 19107203 9832503 16371461 29805709 27462866 20137080 27902311 12040186 19576224 25644994 12615961 19060929 25897075 12851486 15465828 17053159 18952601 10228155 15020233 17444818 20140245 26453498 17052453 16944320 24015932 23602568 24975844 24931005 28948000 20080742 23209942 30271168 28220106 16520547 28430641 11818547 25546293 27672271 11955436 11154277 26373837 16039586 23778311 28697793 20302655 25136145 26905812 22216350 8666229 12957350 23109003 10074433 28529629 20215423 21329734 11254732 9501208 27098453 27281614 30279527 19631635 25482131 18455992 24403311 11274345
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
BTRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 23514615 17053147 22912335 17145710 27001857 20531388 18851830 12820959 24451375 18805092 25900982 11818547 16798748 19061640 19956254 23331499 24912152 19150432 22017875 24501426 28018973 16376880 21466614 27316454 19053519 26506240 14516475 25149538 10023660 22682247 10228155 9461217 24464578 18354482 26091241 10074433 12114015 9990852 14706645 18650423 25873176 19966869 25515538 20851351 22730322 24469040
CTNNA3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25241761 23136403 23718855 11590244 21598020
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
FBXW11 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23331499 9784611 22682247 10074433
FZD5 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
SIAH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 28481365 11389840 32671611
CSNK1D CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10488109 9312064 23331499 11955436 9482734 14966280 10023673 12000790 11818547 12114015
APC2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 23840886 10021369 8638126 16510875 10980707 10074433 9823329
STK4 MOB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18328708 22863277 23431053 21808241
AR NUP214 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17433535 8626436 11059779 15640443 7686046 11006269 12111703 15368351 24307657 9316650 9719026 11867260 12376473 14767470 16275987 11994312 17075604 20181722 9211894 16342680 12917209 18092350 12648523 17011549 11238180 20069563 10547578 16140973 22245379 12539223 20568894 20103546 18758709 21981678 21541973 12463425 12958311 11894840 19389135 17534890 23662037 15923603 16434977 14517289 22695118 10075669 11377978 16137620 11299734 15131260 21780100 16508948 16425097 22473899 14715080 10625666 18640093 21885566 12670590 14729601 16452400 16081584 10898343 11571582 9044850 15833875 16914734 23884959 15640095 15543614 7514587 12376534 12114445 15557561 18780293 23667504 18829551 12782640 16724108 17426252 11504717 19274665 11034093 17566103 12651911 22179832 21308712 16373397 19013180 22155408 9052414 11532861 17094454 17653089 20709811 22654108 22597536 15514031
AR KLK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1712248 19345326 25241761
FNTB FNTA â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 28514442 32296183 16189514 15451670 11687658 12825937 15170324 12036349 33961781 24981860 26186194 15248757
ANAPC2 CDC23 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
BMP4 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7811286 8702914 11282024 8006002
GDF5 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8702914 15890363 9525338 11282024 16127465 15569154 19229295
BMPR2 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 16446785 18756288 10712517 7791754
BMP6 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11401330 10504300
BMP2 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7811286 12700180 9872992 10712517 15064755 19229295
BMP4 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 8702914 23331499 21071413 16446785 12045205 8006002 7673243 7644468
BMP4 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 8702914 26330344 20860622 21054789 11241215 8006002 16189514 7644468
BMP2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 51.0 1.0 Omnipath 17145710 17483092 10880444 10712517 26330344 21054789 16672363 10881198 11263668 20860622 15064755 18937504 25938661 15621726 12700180 10692589 19804412
BMP2 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10880440 23331499 11263668 23180781 18342887 16446785 10880444 10712517 7791754 17295905 25938661 24337809
BMP5 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11580864 16189514
BMPR2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18756288 7791754 10712517
BMP6 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11401330 12297674 10504300
GDF6 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9525338 160490149525338 16049014
GDF7 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16049014
GDF5 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 21543859 9525338 11282024 16127465 19229295
GDF5 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8702914 23331499 9525338 23180781 18342887 16446785 19229295 87029149525338
BMP6 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 16446785 11401330 10504300
GDF7 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16049014
GDF6 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 9525338 16446785 18988627 160490149525338 16049014
FZD2 DVL3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL3 WNT8B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
FZD2 WNT8B â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946